CYB5R3: A key player in aerobic metabolism and aging?

Aging

Volumn 2, Issue 1, 2010, Pages 63-68

  de Cabo, Rafael ^a   Siendones, Emilio ^b   Minor, Robin ^a   Navas, Plácido ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Lifespan; Nqr1; Respiration

Indexed keywords

CYTOCHROME B5 REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN;

AGING; ANIMAL; ENERGY METABOLISM; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW;

AGING; ANIMALS; CYTOCHROME-B(5) REDUCTASE; ENERGY METABOLISM; HUMANS; NAD; SIRTUINS;

EID: 77953400458     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100112     Document Type: Article

References (41)

1. Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth GS. Dietary restriction and life-span, Science. 2002; 296:2141- 2142.
2. Mattison JA, Roth GS, Lane MA, Ingram DK. Dietary restriction in aging nonhuman primates, Interdiscip Top Gerontol. 2007; 35:137-158.
3. Weindruch R and Sohal RS. Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging, N Engl J Med. 1997; 337:986-994.
4. Canto C and Auwerx J. Caloric restriction, SIRT1 and longevity, Trends Endocrinol Metab. 2009; 20:325-331.
5. Lin SJ, Defossez PA, and Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae, Science. 2000; 289:2126-2128.
6. Rogina B and Helfand SL. Sir2 mediates longevity in the fly through a pathway related to calorie restriction, Proc Natl Acad Sci U S A. 2004; 101:15998-16003
7. Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L. SIRT1 protects against microglia-dependent beta amyloid toxicity through inhibiting NF-kappa B signaling, J Biol Chem. 2005; 280:40364-40374.
8. Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, and Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration, Nature. 2002; 418:344-348.
9. Anderson RM, Bitterman KJ, Wood JG, Medvedik O, and Sinclair DA. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae, Nature. 2003; 423:181-185.
10. Anderson RM, Latorre-Esteves M, Neves AR, Lavu S, Medvedik O, Taylor C, Howitz KT, Santos H, and Sinclair DA. Yeast life-span extension by calorie restriction is independent of NAD fluctuation 1, Science. 2003; 302:2124-2126.
11. Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, and Sinclair DA. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase, Science. 2004; 305:390-392.
12. Bordone L, and Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity, Nat Rev Mol Cell Biol. 2005; 6:298-305.
13. Sung B, Park S, Yu BP, and Chung HY. Modulation of PPAR in aging, inflammation, and calorie restriction, J Gerontol A Biol Sci. 2004; 59A:997-1006.
14. Lane MA, Ingram DK, and Roth GS. Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk. Toxicol Sci. 1999; 52:41-48.
15. Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S, and Carruba MO. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS, Science. 2005; 310:314-317.
16. Lopez-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, Hilmer S, Cascajo MV, Allard J, Ingram DK, Navas P, and de Cabo R. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency, Proc Natl Acad Sci U S A. 2006; 103:1768-1773.
17. Canto C and Auwerx J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure, Curr Opin Lipidol. 2009; 20:98-105.
18. Finkel T, Deng CX, and Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature. 2009; 460:587- 591.
19. Vaquero A and Reinberg D. Calorie restriction and the exercise of chromatin, Genes Dev. 2009; 23:1849-1869.
20. Olgun A. Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging, Biogerontology. 2009; 10:531-534.
21. Jimenez-Hidalgo M, Santos-Ocana C, Padilla S, Villalba JM, Lopez-Lluch G, Martin-Montalvo A, Minor RK, Sinclair DA, de Cabo R, and Navas P. NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast, Aging Cell. 2009; 8:140-151.
22. Villalba JM, Navarro F, Cordoba F, Serrano A, Arroyo A, Crane FL, and Navas P. Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport, Proc Natl Acad Sci U S A. 1995; 92:4887- 4891.
23. P. Navas, J.M. Villalba, R. de Cabo, The importance of plasma membrane coenzyme Q in aging and stress responses, Mitochondrion 7 Suppl. 2007; 7:S34-40.
24. Villalba JM and Navas P. Plasma membrane redox system in the control of stress-induced apoptosis, Antioxid Redox Signal. 2000; 2:213-230.
25. De Cabo R, Cabello R, Rios M, Lopez-Lluch G, Ingram DK, Lane MA, and Navas P. Calorie restriction attenuates age- related alterations in the plasma membrane antioxidant system in rat liver, Exp Gerontol. 2004; 139:297-304.
26. Hyun DH, Emerson SS, Jo DG, Mattson MP, and de Cabo R. Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging, Proc Natl Acad Sci U S A. 2006; 103:19908-19912.
27. Gomez-Diaz C, Villalba JM, Perez-Vicente R, Crane FL, and Navas P. Ascorbate stabilization is stimulated in rho(0)HL-60 cells by CoQ10 increase at the plasma membrane, Biochem Biophys Res Commun. 1997; 234:79-81.
28. Hyun DH, Hunt ND, Emerson SS, Hernandez JO, Mattson MP, and de Cabo R. Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria, J Neurochem. 2007; 100:1364-1374.
29. Navarro F, Navas P, Burgess JR, Bello RI, De Cabo R, Arroyo A, and Villalba JM. Vitamin E and selenium deficiency induces expression of the ubiquinone-dependent antioxidant system at the plasma membrane, FASEB J. 1998; 12:1665-1673.
30. S. Padilla, U.C. Tran, M. Jimenez-Hidalgo, J.M. Lopez-Martin, A. Martin-Montalvo, C.F. Clarke, P. Navas, C. Santos-Ocana, Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis, Cell Mol Life Sci. 2009; 66:173- 186.
31. Bonawitz ND, Chatenay-Lapointe M, Pan Y, and Shadel GS. Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression, Cell Metab. 2007; 5:265-277.
32. Smith DL Jr., McClure JM, Matecic M, and Smith JS. Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins, Aging Cell. 2007; 6:649- 662.
33. Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr NA, Rosenzweig A, de Cabo R, Sauve AA, and Sinclair DA. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival, Cell. 2007; 130:1095-1107.
34. Reddy VV, Kupfer D, and Caspi E. Mechanism of C-5 double bond introduction in the biosynthesis of cholesterol by rat liver microsomes. J Biol Chem. 1977; 252:2797-2801.
35. Keyes SR and Cinti DL. Biochemical properties of cytochrome b5-dependent microsomal fatty acid elongation and identification of products. J Biol Chem. 1980; 255:11357-11364.
36. Passon PG and Hultquist DE. Soluble cytochrome b5 reductase from human erythrocytes., Biochim Biophys Acta. 1972; 275:62-73.
37. Jaffé ER. Methemoglobin pathophysiology, Progress Clin Biol Res. 1981; 51:133-151.
38. Percy MJ and Lappin TR. Recessive congenital methaemoglobinemia: cytochrome b5 reductase deficiency., Br J Haematol. 2008; 141:298-308.
39. Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, Klychnikov O, Li KW, Pham TV, Wang J, Miletic H, Peng Z, Bjerkvig R, Jimenez CR, and Niclou SP. iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross- talk in angiogenic compared with invasive glioblastoma phenotype., Mol Cell Proteomics. 2009; 8:2595-2612.
40. Price JA, Rogers JV, McDougal JN, Shaw MQ, Reid FM, Kiser RC, and Graham JS. Gene expression analysis of bromine- induced burns in porcine skin., Toxicol Lett. 2008; 182:69-78.
41. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, and Mann M. Lysine acetylation targets protein complexes and co-regulates major cellular functions., Science. 2009; 325:834-840.