메뉴 건너뛰기




Volumn 25, Issue 3, 2010, Pages 431-436

Of mice and (wo)men: Mouse models of breast cancer metastasis to bone

Author keywords

[No Author keywords available]

Indexed keywords

CANCER ANTIBODY; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; PARATHYROID HORMONE RELATED PROTEIN; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN;

EID: 77953366718     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.68     Document Type: Review
Times cited : (21)

References (75)
  • 2
    • 0036899360 scopus 로고    scopus 로고
    • Future directions in the treatment and prevention of bone metastases
    • Coleman RE. Future directions in the treatment and prevention of bone metastases. Am J Clin Oncol. 2002;25:S32-38.
    • (2002) Am J Clin Oncol , vol.25
    • Coleman, R.E.1
  • 3
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2:584-593.
    • (2002) Nat Rev Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 4
    • 0034175025 scopus 로고    scopus 로고
    • Treatment of metastatic bone disease in breast cancer: Bisphosophonates
    • Diel IJ, Solomayer EF, Bastert G. Treatment of metastatic bone disease in breast cancer: bisphosophonates. Clin Breast Cancer. 2000;1: 43-51.
    • (2000) Clin Breast Cancer , vol.1 , pp. 43-51
    • Diel, I.J.1    Solomayer, E.F.2    Bastert, G.3
  • 5
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • Roodman GD. Mechanisms of bone metastasis. N Engl J Med. 2004;350:1655-1664.
    • (2004) N Engl J Med , vol.350 , pp. 1655-1664
    • Roodman, G.D.1
  • 6
    • 0002838430 scopus 로고
    • The nature of metastatic bone disease
    • Rubens RD, Fogelman I, eds. London: Springer-Verlag
    • Rubens RD. The nature of metastatic bone disease. In: Rubens RD, Fogelman I, eds. Bone Metastases: Diagnosis and Treatment. London: Springer-Verlag; 1992: 1-10.
    • (1992) Bone Metastases: Diagnosis and Treatment , pp. 1-10
    • Rubens, R.D.1
  • 7
    • 1842859068 scopus 로고    scopus 로고
    • Shifting paradigms in tumor metastasis: Challenges and opportunities
    • Parsons JT, Zetter B, Mohla S. Shifting paradigms in tumor metastasis: challenges and opportunities. Cancer Biol Ther. 2002;1:582-585.
    • (2002) Cancer Biol Ther , vol.1 , pp. 582-585
    • Parsons, J.T.1    Zetter, B.2    Mohla, S.3
  • 8
    • 0032768313 scopus 로고    scopus 로고
    • A Novel orthotopic model of breast cancer metastasis to bone
    • Lelekakis M, Moseley JM, Martin TJ, et al. A Novel orthotopic model of breast cancer metastasis to bone. Clin Exp Metastasis. 1999;17:163-170.
    • (1999) Clin Exp Metastasis , vol.17 , pp. 163-170
    • Lelekakis, M.1    Moseley, J.M.2    Martin, T.J.3
  • 9
    • 0029101805 scopus 로고
    • Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
    • 51995
    • Sasaki A, Boyce BF, Story B, et al. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Res. 1995;51995;5:3551-3557.
    • (1995) Cancer Res , Issue.5 , pp. 3551-3557
    • Sasaki, A.1    Boyce, B.F.2    Story, B.3
  • 10
    • 0029791878 scopus 로고    scopus 로고
    • E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model
    • Mbalaviel G, Dunsan CR, Sasaki A, William PJ, Mundy GR, Yoneda T. E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in experimental metastasis model. Cancer Res. 1996;56:4063-4070. (Pubitemid 26284761)
    • (1996) Cancer Research , vol.56 , Issue.17 , pp. 4063-4070
    • Mbalaviele, G.1    Dunstan, C.R.2    Sasaki, A.3    Williams, P.J.4    Mundy, G.R.5    Yoneda, T.6
  • 12
    • 0033561535 scopus 로고    scopus 로고
    • Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone
    • Nemeth JA, Harb JF, Barroros U Jr, He Z, Grignon DJ, Cher ML. Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone. Cancer Res. 1999l;59:1987-1993.
    • (1999) Cancer Res , vol.59 , pp. 1987-1993
    • Nemeth, J.A.1    Harb, J.F.2    Barroros Jr., U.3    He, Z.4    Grignon, D.J.5    Cher, M.L.6
  • 13
    • 0029076829 scopus 로고
    • Species-specific metastasis of human tumor cells in the sever combined immunodeficiency mouse engrafted with human tissue
    • Shtivelman E, Namikawa R. Species-specific metastasis of human tumor cells in the sever combined immunodeficiency mouse engrafted with human tissue. Proc Natl Acad Sci USA. 1995;92: 4661-4665.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4661-4665
    • Shtivelman, E.1    Namikawa, R.2
  • 14
    • 0035266413 scopus 로고    scopus 로고
    • Establishment of a novel species- and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/severe combined immunodeficient mice engrafted with human adult lung and bone
    • Yonou H, Yokose T, Kamijo T, et al. Establishment of a novel species-and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/sever combined immunodeficient mice engrafted with human lung and bone. Cancer Res. 2001;61: 2177-2182. (Pubitemid 32692044)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 2177-2182
    • Yonou, H.1    Yokose, T.2    Kamijo, T.3    Kanomata, N.4    Hasebe, T.5    Nagai, K.6    Hatano, T.7    Ogawa, Y.8    Ochiai, A.9
  • 16
    • 0026503190 scopus 로고    scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res. 2002;52:1399-1405.
    • (2002) Cancer Res , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 17
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • DOI 10.1038/nrc865
    • Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer. 2002;2:563-572. (Pubitemid 37328923)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.8 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 18
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The "seed and soil" hypothesis revisited
    • Fidler IJ. The pathogenesis of cancer metastasis: the "seed and soil" hypothesis revisited. Nat Rev Cancer. 2003;3:453-458.
    • (2003) Nat Rev Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 19
    • 42649100970 scopus 로고    scopus 로고
    • Detection, clinical relevance and specific biological properties of disseminating tumour cells
    • DOI 10.1038/nrc2375, PII NRC2375
    • Pantel K, Brakenhoff RH, Brandt B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nature. 2008;8:329-340. (Pubitemid 351596394)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.5 , pp. 329-340
    • Pantel, K.1    Brakenhoff, R.H.2    Brandt, B.3
  • 20
    • 0034056341 scopus 로고    scopus 로고
    • Cellular and molecular basis of preferential metastasis of breast cancer to bone
    • Yoneda T. Cellular and molecular basis of preferential metastasis of breast cancer to bone. J Orthop Sci. 2000;5:75-81. (Pubitemid 30133795)
    • (2000) Journal of Orthopaedic Science , vol.5 , Issue.1 , pp. 75-81
    • Yoneda, T.1
  • 21
    • 0037303435 scopus 로고    scopus 로고
    • The development and function of the skeleton and bone metastases
    • Rodan GA. The development and function of the skeleton and bone metastases. Cancer. 2003;97:726-732.
    • (2003) Cancer , vol.97 , pp. 726-732
    • Rodan, G.A.1
  • 22
    • 13444306377 scopus 로고    scopus 로고
    • Crosstalk between cancer cells and bone microenvironment in bone metastasis
    • Yoneda T, Hiraga T. Crosstalk between cancer cells and bone microenvironment in bone metastasis. Biochem Biophys Res Commun. 2005;328:679-687.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 679-687
    • Yoneda, T.1    Hiraga, T.2
  • 24
    • 0035009069 scopus 로고    scopus 로고
    • Osteolysis and cancer
    • Goltzman D. Osteolysis and cancer. J Clin Invest. 2001;107:1219-1220.
    • (2001) J Clin Invest , vol.107 , pp. 1219-1220
    • Goltzman, D.1
  • 25
    • 17844383523 scopus 로고    scopus 로고
    • Characterization of a rat model with site-specific bone metastasis induced by MDA-MB-231 breast cancer cells and its application to the effects of an antibody against bone sialoprotein
    • Bäuerie T, Adwan H, Kiessling F, Hilbig H, Armbruster FP, Berger MR. Characterization of a rat model with site-specific bone metastasis induced by MDA-MB-231 breast cancer cells and its application to the effects of an antibody against bone sialoprotein. Int J Cancer. 2005;115:177-186.
    • (2005) Int J Cancer , vol.115 , pp. 177-186
    • Bäuerie, T.1    Adwan, H.2    Kiessling, F.3    Hilbig, H.4    Armbruster, F.P.5    Berger, M.R.6
  • 26
    • 0037301981 scopus 로고    scopus 로고
    • Mechanisms of osteolytic bone metastases in breast carcinoma
    • Käkönen SM, Mundy GR. Mechanisms of osteolytic bone metastases in breast carcinoma. Cancer. 2003;97:834-839.
    • (2003) Cancer , vol.97 , pp. 834-839
    • Käkönen, S.M.1    Mundy, G.R.2
  • 27
    • 0036710458 scopus 로고    scopus 로고
    • Genes involved in breast cancer metastasis to bone
    • Sloan EK, Anderson RL. Genes involved in breast cancer metastasis to bone. Cell Mol Life Sci. 2002;59:1491-1502.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1491-1502
    • Sloan, E.K.1    Anderson, R.L.2
  • 28
    • 0034540852 scopus 로고    scopus 로고
    • Adherence to osteopontin via alphavbeta3 suppresses phorbol ester-mediated apoptosis in MCF-7 breast cancer cells that overexpress protein kinase Cα
    • Noti JD. Adherence to osteopontin via alphavbeta3 suppresses phorbol ester-mediated apoptosis in MCF-7 breast cancer cells that overexpress protein kinase Cα. Int J Oncol. 2000;17:1237-1243.
    • (2000) Int J Oncol , vol.17 , pp. 1237-1243
    • Noti, J.D.1
  • 29
    • 0034055420 scopus 로고    scopus 로고
    • Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers
    • Waltregny D, Bellahcéne A, de Leval X, Florkin B, Weidle U, Castronovo V. Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers. J Bone Miner Res. 2000;15:834-843.
    • (2000) J Bone Miner Res , vol.15 , pp. 834-843
    • Waltregny, D.1    Bellahcéne, A.2    De Leval, X.3    Florkin, B.4    Weidle, U.5    Castronovo, V.6
  • 30
    • 0035058961 scopus 로고    scopus 로고
    • Expression of bone sialoprotein and osteopontin in breast cancer bone metastases
    • Ibrahim T, Leong I, Sanchez-Sweatman O, et al. Expression of bone sialoprotein and osteopontin in breast cancer bone metastases. Clin Exp Metastasis. 2000;18:253-260.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 253-260
    • Ibrahim, T.1    Leong, I.2    Sanchez-Sweatman, O.3
  • 31
    • 0031045940 scopus 로고    scopus 로고
    • Expression of bone matrix proteins in human breast cancer: Potential roles in microcalcification formation and in the genesis of bone metastases
    • Bellahcéne A, Castronovo V. Expression of bone matrix proteins in human breast cancer: potential roles in microcalcification formation and in the genesis of bone metastases. Bull Cancer. 1997;84:17-24.
    • (1997) Bull Cancer , vol.84 , pp. 17-24
    • Bellahcéne, A.1    Castronovo, V.2
  • 32
    • 0034730327 scopus 로고    scopus 로고
    • The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
    • Fata JE, Kong YY, Li J, et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell. 2003;103:41-50.
    • (2003) Cell , vol.103 , pp. 41-50
    • Fata, J.E.1    Kong, Y.Y.2    Li, J.3
  • 33
    • 13444306168 scopus 로고    scopus 로고
    • Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo
    • Javed A, Barnes GL, Pratap J, et al. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Scie USA. 2005;102: 1454-1459.
    • (2005) Proc Natl Acad Scie USA , vol.102 , pp. 1454-1459
    • Javed, A.1    Barnes, G.L.2    Pratap, J.3
  • 34
    • 3042825286 scopus 로고    scopus 로고
    • Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastasis-associated osteolytic disease
    • Barnes GL, Hebert KE, Kamal M, et al. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastasis-associated osteolytic disease. Cancer Res. 2004;64:4506-4513.
    • (2004) Cancer Res , vol.64 , pp. 4506-4513
    • Barnes, G.L.1    Hebert, K.E.2    Kamal, M.3
  • 35
    • 27144434594 scopus 로고    scopus 로고
    • A role for Runx2 in normal mammary gland and breast cancer bone metastasis
    • Shore P. A role for Runx2 in normal mammary gland and breast cancer bone metastasis. J Cell Biochem. 2005;96:484-489.
    • (2005) J Cell Biochem , vol.96 , pp. 484-489
    • Shore, P.1
  • 37
    • 0033757999 scopus 로고    scopus 로고
    • Molecular mechanisms of tumor-bone interactions in osteolytic metastases
    • Chirgwin JM, Guise TA. Molecular mechanisms of tumor-bone interactions in osteolytic metastases. Crit Rev Eukaryot Gene Expr. 2000;10:159-178.
    • (2000) Crit Rev Eukaryot Gene Expr , vol.10 , pp. 159-178
    • Chirgwin, J.M.1    Guise, T.A.2
  • 38
    • 0035824687 scopus 로고    scopus 로고
    • Transforming growth factor beta regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergism
    • Lindemann RK, Ballschmieter P, Nordheim A, Dittmer J. Transforming growth factor beta regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergism. J Biol Chem. 2001;276:46661-46670.
    • (2001) J Biol Chem , vol.276 , pp. 46661-46670
    • Lindemann, R.K.1    Ballschmieter, P.2    Nordheim, A.3    Dittmer, J.4
  • 39
    • 0034658725 scopus 로고    scopus 로고
    • Molecular mechanisms of osteolytic bone metastases
    • Guise TA. Molecular mechanisms of osteolytic bone metastases. Cancer. 2000;88:2892-2898.
    • (2000) Cancer , vol.88 , pp. 2892-2898
    • Guise, T.A.1
  • 40
    • 0032888683 scopus 로고    scopus 로고
    • Factors regulating the growth of metastatic cancer in bone
    • Boyce BF, Yoneda T, Guise TA. Factors regulating the growth of metastatic cancer in bone. Endocr Relat Cancer. 1999;6:333-347.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 333-347
    • Boyce, B.F.1    Yoneda, T.2    Guise, T.A.3
  • 41
    • 0034659929 scopus 로고    scopus 로고
    • Molecular basis of the spectrum of skeletal complications of neoplasia
    • Goltzman D, Karaplis AC, Kremer R, Rabbani SA. Molecular basis of the spectrum of skeletal complications of neoplasia. Cancer. 2000;88: 2903-2908.
    • (2000) Cancer , vol.88 , pp. 2903-2908
    • Goltzman, D.1    Karaplis, A.C.2    Kremer, R.3    Rabbani, S.A.4
  • 42
    • 0037304016 scopus 로고    scopus 로고
    • Role of stromal-derived cytokines and growth factors in bone metastasis
    • Roodman GD. Role of stromal-derived cytokines and growth factors in bone metastasis. Cancer. 2003;97:733-738.
    • (2003) Cancer , vol.97 , pp. 733-738
    • Roodman, G.D.1
  • 43
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med. 2004;10:789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 44
    • 0026472124 scopus 로고
    • Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
    • Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci USA. 1992;89:10578-10582.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10578-10582
    • Guy, C.T.1    Webster, M.A.2    Schaller, M.3    Parsons, T.J.4    Cardiff, R.D.5    Muller, W.J.6
  • 45
    • 0142244181 scopus 로고    scopus 로고
    • Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
    • Lin EY, Jones JG, Li P, Zhu L, Whitney KD, Muller WJ, Pollard JW. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol. 2003;163:2113-2126. (Pubitemid 37310040)
    • (2003) American Journal of Pathology , vol.163 , Issue.5 , pp. 2113-2126
    • Lin, E.Y.1    Jones, J.G.2    Li, P.3    Zhu, L.4    Whitney, K.D.5    Muller, W.J.6    Pollard, J.W.7
  • 46
    • 0028116952 scopus 로고
    • Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene
    • Maroulakou IG, Anver M, Garrett L, Green JE. Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci USA. 1994;91:11236-11240.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11236-11240
    • Maroulakou, I.G.1    Anver, M.2    Garrett, L.3    Green, J.E.4
  • 47
    • 0025772550 scopus 로고
    • Histopathology of salivary and mammary gland tumors in transgenic mice expressing a human Ha-ras oncogene
    • Nielsen LL, Discafani CM, Gurnani M, Tyler RD. Histopathology of salivary and mammary gland tumors in transgenic mice expressing a human Ha-ras oncogene. Cancer Res. 1991;51:3762-3767.
    • (1991) Cancer Res , vol.51 , pp. 3762-3767
    • Nielsen, L.L.1    Discafani, C.M.2    Gurnani, M.3    Tyler, R.D.4
  • 48
    • 0023631608 scopus 로고
    • Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
    • DOI 10.1016/0092-8674(87)90449-1
    • Sinn E, Muller W, Pattengale P, Tepler I, Wallace R, Leder P. Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell. 1987;49:465-475. (Pubitemid 18091823)
    • (1987) Cell , vol.49 , Issue.4 , pp. 465-475
    • Sinn, E.1    Muller, W.2    Pattengale, P.3    Tepler, I.4    Wallace, R.5    Leder, P.6
  • 49
    • 58349086939 scopus 로고    scopus 로고
    • The analysis of metastasis in transgenic mouse models
    • Hüsemann Y, Klein CA. The analysis of metastasis in transgenic mouse models. Transgenic Res. 2009;18:1-5.
    • (2009) Transgenic Res , vol.18 , pp. 1-5
    • Hüsemann, Y.1    Klein, C.A.2
  • 50
    • 0035266285 scopus 로고    scopus 로고
    • Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene
    • Yu Y, Okayasu R, Weil MM, et al. Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene. Cancer Res. 2001;61:1820-1824. (Pubitemid 32691991)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1820-1824
    • Yu, Y.1    Okayasu, R.2    Weil, M.M.3    Silver, A.4    McCarthy, M.5    Zabriskie, R.6    Long, S.7    Cox, R.8    Ullrich, R.L.9
  • 51
    • 1542546126 scopus 로고    scopus 로고
    • Preferential induction of mammary tumors in p53 hemizygous BALB/c mice by fractionated irradiation of a sub-lethal dose of X-rays
    • DOI 10.1269/jrr.44.249
    • Mori N, Yamate J, Umesako S, Hong DP, Okumoto M, Nakao R. Preferential induction of mammary tumors in p53 hemizygous BALB/c mice by fractionated irradiation of a sublethal dose of X-rays. J Radiat Res (Tokyo). 2003;44:249-254. (Pubitemid 38738729)
    • (2003) Journal of Radiation Research , vol.44 , Issue.3 , pp. 249-254
    • Mori, N.1    Yamate, J.2    Umesako, S.-I.3    Hong, D.-P.4    Okumoto, M.5    Nakao, R.6
  • 52
    • 0035420037 scopus 로고    scopus 로고
    • Impact of ionizing radiation and genetic background on mammary tumorigenesis in p53-deficient mice
    • Backlund MG, Trasti SL, Backlund DC, Cressman VL, Godfrey V, Koller BH. Impact of ionizing radiation and genetic background on mammary tumorigenesis in p53-deficient mice. Cancer Res. 2001;61:6577-6582. (Pubitemid 32783267)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6577-6582
    • Backlund, M.G.1    Trasti, S.L.2    Backlund, D.C.3    Cressman, V.L.4    Godfrey, V.5    Koller, B.H.6
  • 53
    • 0020614390 scopus 로고
    • Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: Heterogeneity in phenotypic stability
    • Miller FR, Miller BE, Heppner GH. Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability. Invas Metastasis. 1983;3:22-31.
    • (1983) Invas Metastasis , vol.3 , pp. 22-31
    • Miller, F.R.1    Miller, B.E.2    Heppner, G.H.3
  • 54
    • 19944432209 scopus 로고    scopus 로고
    • Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix
    • Eckhardt BL, Parker BS, van Laar RK, et al. Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix. Mol Cancer Res. 2005;3:1-13.
    • (2005) Mol Cancer Res , vol.3 , pp. 1-13
    • Eckhardt, B.L.1    Parker, B.S.2    Van Laar, R.K.3
  • 56
    • 67349168435 scopus 로고    scopus 로고
    • Role of macrophages in tumour progression
    • Siveen KS, Kuttan G. Role of macrophages in tumour progression. Immunol Lett. 2009;123:97-102.
    • (2009) Immunol Lett , vol.123 , pp. 97-102
    • Siveen, K.S.1    Kuttan, G.2
  • 57
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovic D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol. 2004;4:941-952.
    • (2004) Nat Rev Immunol , vol.4 , pp. 941-952
    • Gabrilovic, D.1
  • 58
    • 37849026029 scopus 로고    scopus 로고
    • Regulatory T cells and tumour immunity: Observations in mice and men
    • Gallimore A, Godkin A. Regulatory T cells and tumour immunity: observations in mice and men. Immunology. 2008;123:157-163.
    • (2008) Immunology , vol.123 , pp. 157-163
    • Gallimore, A.1    Godkin, A.2
  • 59
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer - Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • DeNardo DG, Coussens LM. Inflammation and breast cancer - balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res. 2007;9:212.
    • (2007) Breast Cancer Res , vol.9 , pp. 212
    • DeNardo, D.G.1    Coussens, L.M.2
  • 60
    • 52049120831 scopus 로고    scopus 로고
    • ErbB2 transgenic mice: A tool for investigation of the immune prevention and treatment of mammary carcinomas
    • Quaglino E, Mastini C, Forni G, Cavallo F. ErbB2 transgenic mice: a tool for investigation of the immune prevention and treatment of mammary carcinomas. Curr Protcol Immunol. 2008;20:20.9.1-20.9.10.
    • (2008) Curr Protcol Immunol , vol.20
    • Quaglino, E.1    Mastini, C.2    Forni, G.3    Cavallo, F.4
  • 61
    • 0030843743 scopus 로고    scopus 로고
    • A model for osseous metastasis of human breast cancer established by intrafemur injection of the MDA-MB-435 cells in nude mice
    • Wang CY, Chang YW. A model for osseous metastasis of human breast cancer established by intrafemur injection of the MDAMB-435 cells in nude mice. Anticancer Res. 1997;17:2471-2474. (Pubitemid 27352638)
    • (1997) Anticancer Research , vol.17 , Issue.4 A , pp. 2471-2474
    • Wang, C.Y.1    Chang, Y.W.2
  • 62
    • 0142059049 scopus 로고    scopus 로고
    • Site-specific human breast cancer (MDA-MB-231) metastases in nude rats: Model characterisation and in vivo effects of ibandronate on tumour growth
    • DOI 10.1002/ijc.11397
    • Neuder M, Fischer C, Krempien B, Bauss F, Seibel MJ. Site-specific human breast cancer (MDA-MB-231) metastases in nude rats: model characterization and in vivo effects of ibandronate on tumour growth. Int J Cancer. 2003;107:468-477. (Pubitemid 37266469)
    • (2003) International Journal of Cancer , vol.107 , Issue.3 , pp. 468-477
    • Neudert, M.1    Fischer, C.2    Krempien, B.3    Bauss, F.4    Seibel, M.J.5
  • 63
    • 0030927205 scopus 로고    scopus 로고
    • Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2
    • Yoneda T, Sasaki A, Dunstan C, et al. Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2. J Clin Invest. 1997;99:2509-2517. (Pubitemid 27227730)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.10 , pp. 2509-2517
    • Yoneda, T.1    Sasaki, A.2    Dunstan, C.3    Williams, P.J.4    Bauss, F.5    De Clerck, Y.A.6    Mundy, G.R.7
  • 64
    • 0034783467 scopus 로고    scopus 로고
    • Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: Application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions
    • Peyruchaud O, Winding B, Pécheur I, Serre CM, Delmas P, Clézardin P. Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions. J Bone Miner Res. 2001;16:2027-2034. (Pubitemid 32995393)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.11 , pp. 2027-2034
    • Peyruchaud, O.1    Winding, B.2    Pecheur, I.3    Serre, C.-M.4    Delmas, P.5    Clezardin, P.6
  • 65
    • 41149094679 scopus 로고    scopus 로고
    • Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis
    • Canon JR, Roudier M, Bryant R, et al. Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis. Clin Exp Metastasis. 2008;25:119-129.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 119-129
    • Canon, J.R.1    Roudier, M.2    Bryant, R.3
  • 66
    • 68349160814 scopus 로고    scopus 로고
    • Imaging transforming growth factor-b signaling dynamics and therapeutic response in breast cancer bone metastasis
    • Korpal M, Yan J, Lu X, Xu S, Lerit DA, Kang Y. Imaging transforming growth factor-b signaling dynamics and therapeutic response in breast cancer bone metastasis. Nat Med. 2009;15:960-966.
    • (2009) Nat Med , vol.15 , pp. 960-966
    • Korpal, M.1    Yan, J.2    Lu, X.3    Xu, S.4    Lerit, D.A.5    Kang, Y.6
  • 67
    • 0025192243 scopus 로고
    • Tumorigenicity and metastatis of human breast carcinoma cell lines in nude mice
    • Price JE, Polyzos A, Zhang RD, Daniels LM. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res. 1990;50:717-721. (Pubitemid 20054204)
    • (1990) Cancer Research , vol.50 , Issue.3 , pp. 717-721
    • Price, J.E.1    Polyzos, A.2    Zhang, R.D.3    Daniels, L.M.4
  • 68
    • 0036284307 scopus 로고    scopus 로고
    • Optically imageable metastatic mouse model of human breast cancer
    • Li X, Wang J, An Z, et al. Optically imageable metastatic mouse model of human breast cancer. Clin Exp Metastasis. 2002;9:347-350.
    • (2002) Clin Exp Metastasis , vol.9 , pp. 347-350
    • Li, X.1    Wang, J.2    An, Z.3
  • 69
    • 0033500248 scopus 로고    scopus 로고
    • Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: A bridge to the clinic
    • Hoffman RM. Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drug. 1999;17:343-359.
    • (1999) Invest New Drug , vol.17 , pp. 343-359
    • Hoffman, R.M.1
  • 70
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 2007;449: 557-563.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3
  • 72
    • 35948949806 scopus 로고    scopus 로고
    • Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model
    • DOI 10.1158/0008-5472.CAN-07-2483
    • Moreau JE, Anderson K, Mauney JR, Nguyen T, Kaplan DL, Rosenblatt M. Tissue-engineered bone serves as a target for metastasis ofhuman breast cancer in a mouse model. Cancer Res. 2007;67: 10304-10308. (Pubitemid 350070804)
    • (2007) Cancer Research , vol.67 , Issue.21 , pp. 10304-10308
    • Moreau, J.E.1    Anderson, K.2    Mauney, J.R.3    Nguyen, T.4    Kaplan, D.L.5    Rosenblatt, M.6
  • 74
    • 32644479707 scopus 로고    scopus 로고
    • Electrospun silk-BMP-2 scaffolds for bone tissue engineering
    • DOI 10.1016/j.biomaterials.2006.01.022, PII S0142961206000214
    • Li C, Vepari C, Jin HJ, Kim HJ, Kaplan DL. Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials. 2006;27:3115-3124. (Pubitemid 43247585)
    • (2006) Biomaterials , vol.27 , Issue.16 , pp. 3115-3124
    • Li, C.1    Vepari, C.2    Jin, H.-J.3    Kim, H.J.4    Kaplan, D.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.