Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: Application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions

Journal of Bone and Mineral Research

Volumn 16, Issue 11, 2001, Pages 2027-2034

  Peyruchaud, O ^a   Winding, B ^a   Pecheur I ^a   Serre, C M ^a   Delmas, P ^a   Clezardin P ^a  

^a INSERM   (France)

Author keywords

Bisphosphonate; Bone metastasis; Breast cancer; Green fluorescent protein

Indexed keywords

ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; GREEN FLUORESCENT PROTEIN; ZOLEDRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER GROWTH; CELL CLONING; CONTROLLED STUDY; EARLY DIAGNOSIS; EXPRESSION VECTOR; HEART LEFT VENTRICLE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; OSTEOLYSIS;

ANIMALS; BONE NEOPLASMS; BREAST NEOPLASMS; DIPHOSPHONATES; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; IMIDAZOLES; LUMINESCENT PROTEINS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; OSTEOLYSIS; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

EID: 0034783467     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.11.2027     Document Type: Article

References (21)

1. Positron emission tomography analysis of metastatic tumor cell trafficking
2. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
3. Tumor cells with organ-specific metastatic ability show distinctive trafficking in vivo: Analyses by positron emission tomography and bioimaging
4. Validity and usefulness of human tumor models established by intratibial cell inoculation in nude rats
5. The inhibition by aspirin and indomethacin of osteolytic, tumor deposits and hypercalcemia in rats with Walker tumor, and its possible application to human breast cancer
6. A murine model of experimental metastasis to bone and bone marrow
7. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
8. Cancer and bone
9. Actions of bisphosphonates on bone metastasis in animal models of breast carcinoma
10. Applications of green fluorescent protein in cell biology and biotechnology
11. Multi-organ metastatic capability of Chinese hamster ovary cells revealed by green fluorescent protein (GFP) expression
12. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression
13. Genetically fluorescent melanoma bone and organ metastasis models
14. Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases
15. Widespread skeletal metastatic potential of human lung cancer revealed by green fluorescent protein expression
16. A fluorescent orthotopic bone metastasis model of human prostate cancer
17. Human breast cancer cells induce angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis
18. Preclinical pharmacology of CGP 42′446, a new, potent heterocyclic bisphosphonate compound
19. Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2
20. Bisphosphonates induce apoptosis in human breast cancer cell lines