Cellular mechanisms of bone resorption in breast carcinoma

British Journal of Cancer

Volumn 85, Issue 1, 2001, Pages 78-84

  Hunt, N C A ^a   Fujikawa, Y ^a   Sabokbar, A ^a   Itonaga, I ^a   Harris, A ^a   Athanasou, N A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Bone resorption; Breast cancer; Metastasis; Osteoclast

Indexed keywords

CALCITRIOL; COLONY STIMULATING FACTOR 1; HUMORAL ANTIBODY;

ADULT; AGED; ARTICLE; BONE METASTASIS; BREAST CARCINOMA; CANCER CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; FEMALE; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; HYPERCALCEMIA; MONOCYTE; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; BONE NEOPLASMS; BONE RESORPTION; BREAST NEOPLASMS; CALCITRIOL; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MIDDLE AGED; MONOCYTES; OSTEOCLASTS; PARATHYROID HORMONE-RELATED PROTEIN; PROTEINS;

EID: 0035816314     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.1856     Document Type: Article

References (40)

1. The mouse mammary tumor cell line MMT06562 produces prostaglandin E2 and leukemia inhibitory factor and supports osteoclast formation in vitro via a stromal dependent pathway
2. Osteoclastogenesis inhibitory factor exhibit hypocalcemic effect in normal mice and in hypercalcemic nude mice carrying tumors associated with humoral hypercalcemia of malignangy
3. Acid phosphatases
4. The cellular biology of bone-resorbing cells
5. Immunophenotypic differences between osteoclasts and macrophage polykaryons: Immunohistological distinction and implications for osteoclast ontogeny and function
6. Resorption of dentine by isolated osteoclasts in vitro
7. Macrophage content of spontaneous metastases at different stages of growth
8. Osteoclasts are required for bone tumors to grow and destroy bone
9. Localised tumor-associated osteolysis involves the recruitment and activation of osteoclasts
10. Human breast cancer induces osteoclast activation and increases the number of osteoclasts at sites of tumor osteolysis
11. Malignant bone resorption: Cellular and biochemical mechanisms
12. The human mononuclear osteoclast precursor circulates in the monocyte fraction
13. The effect of macrophage-colony stimulating factor and other humoral factors (Interleuken-1, -3, -6, - 11, tumour necrosis factor-α granulocyte macrophage-colony stimulating factor) on human osteoclast formation from circulating cells
14. Mechanisms of bone destruction in the development of skeletal metastasis
15. The use of monoclonal antibodies in histological diagnosis
16. Breast cancer cell line MDA-231 stimulates osteoclastogenesis and bone resorption in human osteoclasts
17. Monoclonal antibodies to osteoclastomas (giant cell bone tumours): Definition of osteoclast specific cellular antigens
18. Osteoclast formation from circulating precursors in primary and secondary osteoporosis
19. CSF-1 and its receptor in ovarian, endometrial and breast cancer
20. Isolation of murine osteoclast colony-stimulating factor
21. The origin and function of tumour-associated macrophages
22. Mechanisms of osteolytic bone destruction
23. RANK is the essential signalling receptor for osteoclast differentiation factor in osteoclastogenesis
24. Mouse mammary carcinoma cell line (BALB/c-MC) stimulates osteoclast formation from mouse bone marrow cells through cell-to-cell contact
25. Functional properties of hormonal responsive cultured normal and malignant rat osteoblastic cells
26. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice
27. Cellular and hormonal mechanisms associated with malignant bone resorption
28. Cells of the mononuclear phagocyte series differentiate into osteoclastic lacunar bone-resorbing cells
29. Human turnour-associated macrophages differentiate into osteoclastic bone resorbing cells
30. Mechanisms of cancer-induced hypercalcaemia
31. Characterization of osteoclast prescursors in human blood
32. A human cell line from a pleural effusion derived from a breast carcinoma
33. Modulation of cell differentiation, immune response and tumor promotion by vitamin D components
34. Macrophage colony stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors
35. Histomorphometric evidence for osteoclast-mediated bone resorption in metastatic breast cancer
36. Breast cancer cells stimulate osteoblastic osteoclast differentiation factor (ODF) to support osteoclast formation
37. Origin of osteoclasts: Mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone-marrow derived stromal cells
38. Tumor infiltrating cells in human cancer: On the possible role of CD16+ macrophages in antitumor cytotoxicity
39. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and identical to TRANCE/RANKL