메뉴 건너뛰기




Volumn 4, Issue 3, 2010, Pages 373-385

The physical basis of ventilator-induced lung injury

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Esophageal pressure; Lung strain; Lung stress; Mechanical ventilation; Mechanotransduction; Plateau pressure; Ventilator induced lung injury

Indexed keywords

ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; BIOMECHANICS; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; ELASTOGRAPHY; HUMAN; LUNG ALVEOLUS CELL; LUNG COMPLIANCE; LUNG INFLATION; LUNG PARENCHYMA; MECHANOTRANSDUCTION; NONHUMAN; PATHOPHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; REVIEW; STRESS STRAIN RELATIONSHIP; THERAPY EFFECT; VENTILATOR INDUCED LUNG INJURY;

EID: 77953254293     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.10.28     Document Type: Review
Times cited : (91)

References (145)
  • 3
    • 0343893748 scopus 로고    scopus 로고
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 342(18), 1301-1308 (2000).
    • (2000) N. Engl. J. Med. , vol.342 , Issue.18 , pp. 1301-1308
  • 4
    • 3242703034 scopus 로고    scopus 로고
    • Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome
    • Brower RG, Lanken PN, MacIntyre N et al. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N. Engl. J. Med. 351(4), 327-336 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , Issue.4 , pp. 327-336
    • Brower, R.G.1    Lanken, P.N.2    MacIntyre, N.3
  • 5
    • 33645865234 scopus 로고    scopus 로고
    • Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome
    • Steinberg KP, Hudson LD, Goodman RB et al. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N. Engl. J. Med. 354(16), 1671-1684 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , Issue.16 , pp. 1671-1684
    • Steinberg, K.P.1    Hudson, L.D.2    Goodman, R.B.3
  • 6
    • 61449086443 scopus 로고    scopus 로고
    • Has mortality from acute respiratory distress syndrome decreased over time? A systematic review
    • Phua J, Badia JR, Adhikari NK et al. Has mortality from acute respiratory distress syndrome decreased over time? A systematic review. Am. J. Respir. Crit. Care Med. 179(3), 220-227 (2009).
    • (2009) Am. J. Respir. Crit. Care Med. , vol.179 , Issue.3 , pp. 220-227
    • Phua, J.1    Badia, J.R.2    Adhikari, N.K.3
  • 7
    • 43649105058 scopus 로고    scopus 로고
    • Mortality rates for patients with acute lung injury/ARDS have decreased over time
    • Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 133(5), 1120-1127 (2008).
    • (2008) Chest , vol.133 , Issue.5 , pp. 1120-1127
    • Zambon, M.1    Vincent, J.L.2
  • 8
    • 78651146853 scopus 로고
    • Effect of positive pressure ventilation on surface tension properties of lung extracts
    • Greenfield LJ, Ebert PA, Benson DW. Effect of positive pressure ventilation on surface tension properties of lung extracts. Anesthesiology 25, 312-316 (1964).
    • (1964) Anesthesiology , vol.25 , pp. 312-316
    • Greenfield, L.J.1    Ebert, P.A.2    Benson, D.W.3
  • 10
    • 0037308350 scopus 로고    scopus 로고
    • Response of alveolar cells to mechanical stress
    • Vlahakis NE, Hubmayr RD. Response of alveolar cells to mechanical stress. Curr. Opin. Crit. Care 9(1), 2-8 (2003).
    • (2003) Curr. Opin. Crit. Care , vol.9 , Issue.1 , pp. 2-8
    • Vlahakis, N.E.1    Hubmayr, R.D.2
  • 11
    • 20444392352 scopus 로고    scopus 로고
    • Cellular stress failure in ventilator-injured lungs
    • Vlahakis NE, Hubmayr RD. Cellular stress failure in ventilator-injured lungs. Am. J. Respir. Crit. Care Med. 171(12), 1328-1342 (2005).
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , Issue.12 , pp. 1328-1342
    • Vlahakis, N.E.1    Hubmayr, R.D.2
  • 12
    • 0022741050 scopus 로고
    • Adult respiratory distress syndrome profiles by computed tomography
    • Gattinoni L, Pesenti A, Torresin A et al. Adult respiratory distress syndrome profiles by computed tomography. J. Thorac. Imag. 3, 25-30 (1986).
    • (1986) J. Thorac. Imag. , vol.3 , pp. 25-30
    • Gattinoni, L.1    Pesenti, A.2    Torresin, A.3
  • 14
    • 0002208740 scopus 로고
    • ARDS: The non-homogeneous lung; Facts and hypothesis
    • Gattinoni L, Pesenti A. ARDS: the non-homogeneous lung; facts and hypothesis. Intensive Crit. Care Dig. 6, 1-4 (1987).
    • (1987) Intensive Crit. Care Dig. , vol.6 , pp. 1-4
    • Gattinoni, L.1    Pesenti, A.2
  • 15
  • 16
    • 0023473172 scopus 로고
    • Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study
    • Gattinoni L, Pesenti A, Avalli L, Rossi F, Bombino M. Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study. Am. Rev. Resp. Dis. 136(3), 730-736 (1987).
    • (1987) Am. Rev. Resp. Dis. , vol.136 , Issue.3 , pp. 730-736
    • Gattinoni, L.1    Pesenti, A.2    Avalli, L.3    Rossi, F.4    Bombino, M.5
  • 17
    • 0023937536 scopus 로고
    • High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure
    • Dreyfuss D, Soler P, Basset G, Saumon G. High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am. Rev. Resp. Dis. 137(5), 1159-1164 (1988).
    • (1988) Am. Rev. Resp. Dis. , vol.137 , Issue.5 , pp. 1159-1164
    • Dreyfuss, D.1    Soler, P.2    Basset, G.3    Saumon, G.4
  • 18
    • 0035509119 scopus 로고    scopus 로고
    • What has computed tomography taught us about the acute respiratory distress syndrome?
    • Gattinoni L, Caironi P, Pelosi P, Goodman LR. What has computed tomography taught us about the acute respiratory distress syndrome? Am. J. Respir. Crit. Care Med. 164(9), 1701-1711 (2001).
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.9 , pp. 1701-1711
    • Gattinoni, L.1    Caironi, P.2    Pelosi, P.3    Goodman, L.R.4
  • 19
    • 0027456856 scopus 로고
    • The ARDS lung. New insights from computed tomography
    • Bone RC. The ARDS lung. New insights from computed tomography. JAMA 269(16), 2134-2135 (1993).
    • (1993) JAMA , vol.269 , Issue.16 , pp. 2134-2135
    • Bone, R.C.1
  • 20
    • 0037098049 scopus 로고    scopus 로고
    • Perspective on lung injury and recruitment: A skeptical look at the opening and collapse story
    • Hubmayr RD. Perspective on lung injury and recruitment: a skeptical look at the opening and collapse story. Am. J. Respir. Crit. Care Med. 165(12), 1647-1653 (2002).
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , Issue.12 , pp. 1647-1653
    • Hubmayr, R.D.1
  • 22
    • 0022549667 scopus 로고
    • Surface forces in lungs. I. Alveolar surface tension-lung volume relationships
    • Smith JC, Stamenovic D. Surface forces in lungs. I. Alveolar surface tension-lung volume relationships. J. Appl. Physiol. 60(4), 1341-1350 (1986). (Pubitemid 16028436)
    • (1986) Journal of Applied Physiology , vol.60 , Issue.4 , pp. 1341-1350
    • Smith, J.C.1    Stamenovic, D.2
  • 23
    • 0022552021 scopus 로고
    • Surface forces in lungs. III. Alveolar surface tension and elastic properties of lung parenchyma
    • Stamenovic D, Smith JC. Surface forces in lungs. III. Alveolar surface tension and elastic properties of lung parenchyma. J. Appl. Physiol. 60(4), 1358-1362 (1986).
    • (1986) J. Appl. Physiol. , vol.60 , Issue.4 , pp. 1358-1362
    • Stamenovic, D.1    Smith, J.C.2
  • 24
    • 0022553777 scopus 로고
    • Surface forces in lungs. II. Microstructural mechanics and lung stability
    • Stamenovic D, Smith JC. Surface forces in lungs. II. Microstructural mechanics and lung stability. J. Appl. Physiol. 60(4), 1351-1357 (1986).
    • (1986) J. Appl. Physiol. , vol.60 , Issue.4 , pp. 1351-1357
    • Stamenovic, D.1    Smith, J.C.2
  • 26
    • 69349083011 scopus 로고    scopus 로고
    • Another look at the opening and collapse story
    • Hubmayr RD. Another look at the opening and collapse story. Crit. Care Med. 37(9), 2667-2668 (2009).
    • (2009) Crit. Care Med. , vol.37 , Issue.9 , pp. 2667-2668
    • Hubmayr, R.D.1
  • 27
    • 69349102977 scopus 로고    scopus 로고
    • Alveolar dynamics in acute lung injury: Heterogeneous distension rather than cyclic opening and collapse
    • Mertens M, Tabuchi A, Meissner S et al. Alveolar dynamics in acute lung injury: heterogeneous distension rather than cyclic opening and collapse. Crit. Care Med. 37(9), 2604-2611 (2009).
    • (2009) Crit. Care Med. , vol.37 , Issue.9 , pp. 2604-2611
    • Mertens, M.1    Tabuchi, A.2    Meissner, S.3
  • 28
    • 0007175641 scopus 로고    scopus 로고
    • The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome
    • Artigas A, Bernard GR, Carlet J et al. The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 157(4 Pt 1), 1332-1347 (1998).
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , Issue.4 PART 1 , pp. 1332-1347
    • Artigas, A.1    Bernard, G.R.2    Carlet, J.3
  • 29
    • 0035152627 scopus 로고    scopus 로고
    • Pathology of the surfactant system of the mature lung: Second San Diego conference
    • Spragg RG, Lewis JF. Pathology of the surfactant system of the mature lung: second San Diego conference. Am. J. Respir. Crit. Care Med. 163(1), 280-282 (2001).
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , Issue.1 , pp. 280-282
    • Spragg, R.G.1    Lewis, J.F.2
  • 30
    • 33749723871 scopus 로고
    • Pulmonary mechanics during induced pulmonary edema in anesthetized dogs
    • Cook CD, Mead J, Schreiner GL, Frank NR, Craig JM. Pulmonary mechanics during induced pulmonary edema in anesthetized dogs. J. Appl. Physiol. 14(2), 177-186 (1959).
    • (1959) J. Appl. Physiol. , vol.14 , Issue.2 , pp. 177-186
    • Cook, C.D.1    Mead, J.2    Schreiner, G.L.3    Frank, N.R.4    Craig, J.M.5
  • 31
    • 0018907069 scopus 로고
    • Acute effects on airways mechanics of pulmonary edema induced by intravenous oleic acid in dogs
    • Delaunois L, Sergysels R, Martin RR. Acute effects on airways mechanics of pulmonary edema induced by intravenous oleic acid in dogs. Bull. Eur. Physiopathol. Respir. 16(1), 47-55 (1980).
    • (1980) Bull. Eur. Physiopathol. Respir. , vol.16 , Issue.1 , pp. 47-55
    • Delaunois, L.1    Sergysels, R.2    Martin, R.R.3
  • 32
    • 0018597390 scopus 로고
    • The effect of pulmonary edema on gas trapping in excised rat lungs
    • Frazer DG, Stengel PW, Weber KC. The effect of pulmonary edema on gas trapping in excised rat lungs. Resp. Physiol. 38(3), 325-333 (1979).
    • (1979) Resp. Physiol. , vol.38 , Issue.3 , pp. 325-333
    • Frazer, D.G.1    Stengel, P.W.2    Weber, K.C.3
  • 33
    • 0020536619 scopus 로고
    • Mechanisms of airway narrowing in acute pulmonary oedema in dogs: Influence of the vagus and lung volume
    • Chung KF, Keyes SJ, Morgan BM, Jones PW, Snashall PD. Mechanisms of airway narrowing in acute pulmonary oedema in dogs: influence of the vagus and lung volume. Clin. Sci. (Lond.) 65(3), 289-296 (1983).
    • (1983) Clin. Sci. (Lond.) , vol.65 , Issue.3 , pp. 289-296
    • Chung, K.F.1    Keyes, S.J.2    Morgan, B.M.3    Jones, P.W.4    Snashall, P.D.5
  • 34
    • 0019504328 scopus 로고
    • Gas exchange and respiratory mechanics in moderate and severe pulmonary oedema in dogs
    • Derks CM, D'Hollander AA, Jacobovitz- Derks D. Gas exchange and respiratory mechanics in moderate and severe pulmonary oedema in dogs. Bull. Eur. Physiopathol. Respir. 17(2), 163-177 (1981).
    • (1981) Bull. Eur. Physiopathol. Respir. , vol.17 , Issue.2 , pp. 163-177
    • Derks, C.M.1    D'Hollander, A.A.2    Jacobovitz- Derks, D.3
  • 35
    • 0019914105 scopus 로고
    • Respiratory failure after endotoxin infusion in sheep: Lung mechanics and lung fluid balance
    • Esbenshade AM, Newman JH, Lams PM, Jolles H, Brigham KL. Respiratory failure after endotoxin infusion in sheep: lung mechanics and lung fluid balance. J. Appl. Physiol. 53(4), 967-976 (1982).
    • (1982) J. Appl. Physiol. , vol.53 , Issue.4 , pp. 967-976
    • Esbenshade, A.M.1    Newman, J.H.2    Lams, P.M.3    Jolles, H.4    Brigham, K.L.5
  • 36
    • 0014786734 scopus 로고
    • Stress distribution in lungs: A model of pulmonary elasticity
    • Mead J, Takishima T, Leith D. Stress distribution in lungs: a model of pulmonary elasticity. J. Appl. Physiol. 28(5), 596-608 (1970).
    • (1970) J. Appl. Physiol. , vol.28 , Issue.5 , pp. 596-608
    • Mead, J.1    Takishima, T.2    Leith, D.3
  • 38
    • 0037308661 scopus 로고    scopus 로고
    • Mechanisms of surface-tension-induced epithelial cell damage in a model of pulmonary airway reopening
    • Bilek AM, Dee KC, Gaver DP 3rd. Mechanisms of surface-tension-induced epithelial cell damage in a model of pulmonary airway reopening. J. Appl. Physiol. 94(2), 770-783 (2003).
    • (2003) J. Appl. Physiol. , vol.94 , Issue.2 , pp. 770-783
    • Bilek, A.M.1    Dee, K.C.2    Gaver III, D.P.3
  • 39
    • 0031874223 scopus 로고    scopus 로고
    • A theoretical model study of the influence of fluid stresses on a cell adhering to a microchannel wall
    • Gaver DP 3rd, Kute SM. A theoretical model study of the influence of fluid stresses on a cell adhering to a microchannel wall. Biophys. J. 75(2), 721-733 (1998).
    • (1998) Biophys. J. , vol.75 , Issue.2 , pp. 721-733
    • Gaver III, D.P.1    Kute, S.M.2
  • 40
    • 37649009647 scopus 로고    scopus 로고
    • Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems
    • Huh D, Fujioka H, Tung YC et al. Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems. Proc. Natl Acad. Sci. USA 104(48), 18886-18891 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.48 , pp. 18886-18891
    • Huh, D.1    Fujioka, H.2    Tung, Y.C.3
  • 42
    • 0021860979 scopus 로고
    • Regional lung strain in dogs during deflation from total lung capacity
    • Rodarte JR, Hubmayr RD, Stamenovic D, Walters BJ. Regional lung strain in dogs during deflation from total lung capacity. J. Appl. Physiol. 58(1), 164-172 (1985).
    • (1985) J. Appl. Physiol. , vol.58 , Issue.1 , pp. 164-172
    • Rodarte, J.R.1    Hubmayr, R.D.2    Stamenovic, D.3    Walters, B.J.4
  • 43
    • 48949099318 scopus 로고    scopus 로고
    • Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome
    • Chiumello D, Carlesso E, Cadringher P et al. Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 178(4), 346-355 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , Issue.4 , pp. 346-355
    • Chiumello, D.1    Carlesso, E.2    Cadringher, P.3
  • 45
    • 0001704121 scopus 로고
    • Mechanics of the pleural space
    • Geiger S (Ed.). American Physiological Society, MD, USA
    • Agostoni E. Mechanics of the pleural space. In: Handbook of Physiology. Geiger S (Ed.). American Physiological Society, MD, USA, 531-559 (1986).
    • (1986) Handbook of Physiology , pp. 531-559
    • Agostoni, E.1
  • 46
    • 0015041106 scopus 로고
    • Partition of factors contributing to the vertical gradient of transpulmonary pressure
    • D'Angelo E, Michelini S, Agostoni E. Partition of factors contributing to the vertical gradient of transpulmonary pressure. Respir. Physiol. 12(1), 90-101 (1971).
    • (1971) Respir. Physiol. , vol.12 , Issue.1 , pp. 90-101
    • D'Angelo, E.1    Michelini, S.2    Agostoni, E.3
  • 47
    • 4244207061 scopus 로고
    • Distribution of stresses within the lung
    • Fishman A (Ed.). Williams and Wilkins Co., MD, USA
    • Rodarte J, Fung Y. Distribution of stresses within the lung. In: Handbook of Physiology. Section 3: Respiratory System. Fishman A (Ed.). Williams and Wilkins Co., MD, USA, 233-246 (1986).
    • (1986) Handbook of Physiology. Section 3: Respiratory System , pp. 233-246
    • Rodarte, J.1    Fung, Y.2
  • 49
    • 0034027855 scopus 로고    scopus 로고
    • The prone position eliminates compression of the lungs by the heart
    • Albert RK, Hubmayr RD. The prone position eliminates compression of the lungs by the heart. Am. J. Respir. Crit. Care Med. 161(5), 1660-1665 (2000).
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.5 , pp. 1660-1665
    • Albert, R.K.1    Hubmayr, R.D.2
  • 50
    • 0022506054 scopus 로고
    • Effect of heart weight on distribution of lung surface pressures in vertical dogs
    • Bar-Yishay E, Hyatt RE, Rodarte JR. Effect of heart weight on distribution of lung surface pressures in vertical dogs. J. Appl. Physiol. 61(2), 712-718 (1986).
    • (1986) J. Appl. Physiol. , vol.61 , Issue.2 , pp. 712-718
    • Bar-Yishay, E.1    Hyatt, R.E.2    Rodarte, J.R.3
  • 51
    • 0014748137 scopus 로고
    • The effect of the abdomen on the vertical gradient of pleural surface pressure
    • Agostoni E, D'Angelo E, Bonanni MV. The effect of the abdomen on the vertical gradient of pleural surface pressure. Respir. Physiol. 8(3), 332-346 (1970).
    • (1970) Respir. Physiol. , vol.8 , Issue.3 , pp. 332-346
    • Agostoni, E.1    D'Angelo, E.2    Bonanni, M.V.3
  • 52
    • 0036092905 scopus 로고    scopus 로고
    • Spatial distribution of ventilation and perfusion in anesthetized dogs in lateral postures
    • Chang H, Lai-Fook SJ, Domino KB et al. Spatial distribution of ventilation and perfusion in anesthetized dogs in lateral postures. J. Appl. Physiol. 92(2), 745-762 (2002).
    • (2002) J. Appl. Physiol. , vol.92 , Issue.2 , pp. 745-762
    • Chang, H.1    Lai-Fook, S.J.2    Domino, K.B.3
  • 53
    • 0023574785 scopus 로고
    • Regional ventilation during spontaneous breathing and mechanical ventilation in dogs
    • Hubmayr RD, Rodarte JR, Walters BJ, Tonelli FM. Regional ventilation during spontaneous breathing and mechanical ventilation in dogs. J. Appl. Physiol. 63(6), 2467-2475 (1987).
    • (1987) J. Appl. Physiol. , vol.63 , Issue.6 , pp. 2467-2475
    • Hubmayr, R.D.1    Rodarte, J.R.2    Walters, B.J.3    Tonelli, F.M.4
  • 54
    • 0013514321 scopus 로고
    • Structure-function relationships at the alveolar level
    • West JB (Ed.). Dekker, NY, USA
    • Weibel ER, Gil J. Structure-function relationships at the alveolar level. In: Bioengineering Aspects of the Lung. West JB (Ed.). Dekker, NY, USA, 1-81 (1977).
    • (1977) Bioengineering Aspects of the Lung , pp. 1-81
    • Weibel, E.R.1    Gil, J.2
  • 55
    • 0019951291 scopus 로고
    • A model for mechanical structure of the alveolar duct
    • Wilson TA, Bachofen H. A model for mechanical structure of the alveolar duct. J. Appl. Physiol. 52(4), 1064-1070 (1982).
    • (1982) J. Appl. Physiol. , vol.52 , Issue.4 , pp. 1064-1070
    • Wilson, T.A.1    Bachofen, H.2
  • 56
    • 17644421823 scopus 로고    scopus 로고
    • Biomechanics of the lung parenchyma: Critical roles of collagen and mechanical forces
    • Suki B, Ito S, Stamenovic D, Lutchen KR, Ingenito EP. Biomechanics of the lung parenchyma: critical roles of collagen and mechanical forces. J. Appl. Physiol. 98(5), 1892-1899 (2005).
    • (2005) J. Appl. Physiol. , vol.98 , Issue.5 , pp. 1892-1899
    • Suki, B.1    Ito, S.2    Stamenovic, D.3    Lutchen, K.R.4    Ingenito, E.P.5
  • 57
    • 0026245524 scopus 로고
    • Integrins as mechanochemical transducers
    • Ingber D. Integrins as mechanochemical transducers. Curr. Opin. Cell Biol. 3(5), 841-848 (1991).
    • (1991) Curr. Opin. Cell Biol. , vol.3 , Issue.5 , pp. 841-848
    • Ingber, D.1
  • 58
    • 0031041821 scopus 로고    scopus 로고
    • A new molecular model for collagen elasticity based on synchrotron X-ray scattering evidence
    • Misof K, Rapp G, Fratzl P. A new molecular model for collagen elasticity based on synchrotron X-ray scattering evidence. Biophys. J. 72(3), 1376-1381 (1997).
    • (1997) Biophys. J. , vol.72 , Issue.3 , pp. 1376-1381
    • Misof, K.1    Rapp, G.2    Fratzl, P.3
  • 59
    • 0141617173 scopus 로고    scopus 로고
    • Alveolar surface forces and lung architecture
    • Bachofen H, Schurch S. Alveolar surface forces and lung architecture. Comp. Biochem. Physiol. 129(1), 183-193 (2001).
    • (2001) Comp. Biochem. Physiol. , vol.129 , Issue.1 , pp. 183-193
    • Bachofen, H.1    Schurch, S.2
  • 60
    • 0033061238 scopus 로고    scopus 로고
    • Alveolar epithelial surface area-volume relationship in isolated rat lungs
    • Tschumperlin DJ, Margulies SS. Alveolar epithelial surface area-volume relationship in isolated rat lungs. J. Appl. Physiol. 86(6), 2026-2033 (1999).
    • (1999) J. Appl. Physiol. , vol.86 , Issue.6 , pp. 2026-2033
    • Tschumperlin, D.J.1    Margulies, S.S.2
  • 61
    • 0033852416 scopus 로고    scopus 로고
    • Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology
    • CT Scan ARDS Study Group
    • Puybasset L, Cluzel P, Gusman P et al. Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology. CT Scan ARDS Study Group. Intensive Care Med. 26(7), 857-869 (2000).
    • (2000) Intensive Care Med. , vol.26 , Issue.7 , pp. 857-869
    • Puybasset, L.1    Cluzel, P.2    Gusman, P.3
  • 62
    • 0033803030 scopus 로고    scopus 로고
    • Regional distribution of gas and tissue in acute respiratory distress syndrome. III. Consequences for the effects of positive end-expiratory pressure
    • CT Scan ARDS Study Group. Adult Respiratory Distress Syndrome
    • Puybasset L, Gusman P, Muller JC et al. Regional distribution of gas and tissue in acute respiratory distress syndrome. III. Consequences for the effects of positive end-expiratory pressure. CT Scan ARDS Study Group. Adult Respiratory Distress Syndrome. Intensive Care Med. 26(9), 1215-1227 (2000).
    • (2000) Intensive Care Med. , vol.26 , Issue.9 , pp. 1215-1227
    • Puybasset, L.1    Gusman, P.2    Muller, J.C.3
  • 63
    • 77749316982 scopus 로고    scopus 로고
    • Lung opening and closing during ventilation of acute respiratory distress syndrome
    • Caironi P, Cressoni M, Chiumello D et al. Lung opening and closing during ventilation of acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 181, 578-586, (2010).
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , pp. 578-586
    • Caironi, P.1    Cressoni, M.2    Chiumello, D.3
  • 64
    • 33646115657 scopus 로고    scopus 로고
    • Lung recruitment in patients with the acute respiratory distress syndrome
    • Gattinoni L, Caironi P, Cressoni M et al. Lung recruitment in patients with the acute respiratory distress syndrome. N. Engl. J. Med. 354(17), 1775-1786 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , Issue.17 , pp. 1775-1786
    • Gattinoni, L.1    Caironi, P.2    Cressoni, M.3
  • 65
    • 3142668883 scopus 로고    scopus 로고
    • Incidence and regional distribution of lung overinflation during mechanical ventilation with positive end-expiratory pressure
    • Nieszkowska A, Lu Q, Vieira S et al. Incidence and regional distribution of lung overinflation during mechanical ventilation with positive end-expiratory pressure. Crit. Care Med. 32(7), 1496-1503 (2004).
    • (2004) Crit. Care Med. , vol.32 , Issue.7 , pp. 1496-1503
    • Nieszkowska, A.1    Lu, Q.2    Vieira, S.3
  • 67
    • 74049139857 scopus 로고    scopus 로고
    • Ultrasound assessment of antibiotic-induced pulmonary reaeration in ventilator-associated pneumonia
    • Bouhemad B, Liu ZH, Arbelot C et al. Ultrasound assessment of antibiotic-induced pulmonary reaeration in ventilator-associated pneumonia. Crit. Care Med. 38(1), 84-92 (2010).
    • (2010) Crit. Care Med. , vol.38 , Issue.1 , pp. 84-92
    • Bouhemad, B.1    Liu, Z.H.2    Arbelot, C.3
  • 68
    • 18344372086 scopus 로고    scopus 로고
    • Mechanical ventilation in ARDS: One size does not fit all
    • Deans KJ, Minneci PC, Cui X et al. Mechanical ventilation in ARDS: one size does not fit all. Crit. Care Med. 33(5), 1141-1143 (2005).
    • (2005) Crit. Care Med. , vol.33 , Issue.5 , pp. 1141-1143
    • Deans, K.J.1    Minneci, P.C.2    Cui, X.3
  • 69
    • 0001049878 scopus 로고    scopus 로고
    • Respiratory pressure-volume curves
    • Tobin M (Ed.). McGraw-Hill, NY, USA
    • Brochard L. Respiratory pressure-volume curves. In: Principles and Practice of Intensive Care Monitoring. Tobin M (Ed.). McGraw-Hill, NY, USA, 597-616 (1997).
    • (1997) Principles and Practice of Intensive Care Monitoring , pp. 597-616
    • Brochard, L.1
  • 72
    • 0027737785 scopus 로고
    • Mechanical ventilation. American College of Chest Physicians' Consensus Conference
    • Slutsky AS. Mechanical ventilation. American College of Chest Physicians' Consensus Conference. Chest 104(6), 1833-1859 (1993).
    • (1993) Chest , vol.104 , Issue.6 , pp. 1833-1859
    • Slutsky, A.S.1
  • 73
    • 7944227688 scopus 로고    scopus 로고
    • Bench-to-bedside review: Chest wall elastance in acute lung injury/acute respiratory distress syndrome patients
    • Gattinoni L, Chiumello D, Carlesso E, Valenza F. Bench-to-bedside review: chest wall elastance in acute lung injury/acute respiratory distress syndrome patients. Crit. Care 8(5), 350-355 (2004).
    • (2004) Crit. Care , vol.8 , Issue.5 , pp. 350-355
    • Gattinoni, L.1    Chiumello, D.2    Carlesso, E.3    Valenza, F.4
  • 74
    • 38149128093 scopus 로고    scopus 로고
    • The chest wall in acute lung injury/acute respiratory distress syndrome
    • Hess DR, Bigatello LM. The chest wall in acute lung injury/acute respiratory distress syndrome. Curr. Opin. Crit. Care 14(1), 94-102 (2008).
    • (2008) Curr. Opin. Crit. Care , vol.14 , Issue.1 , pp. 94-102
    • Hess, D.R.1    Bigatello, L.M.2
  • 75
    • 33646586991 scopus 로고    scopus 로고
    • Esophageal and transpulmonary pressures in acute respiratory failure
    • Talmor D, Sarge T, O'Donnell CR et al. Esophageal and transpulmonary pressures in acute respiratory failure. Crit. Care Med. 34(5), 1389-1394 (2006).
    • (2006) Crit. Care Med. , vol.34 , Issue.5 , pp. 1389-1394
    • Talmor, D.1    Sarge, T.2    O'Donnell, C.R.3
  • 76
    • 77949646745 scopus 로고    scopus 로고
    • Esophageal pressures in acute lung injury-do they represent artifact or useful information about transpulmonary pressure, chest wall mechanics, and lung stress?
    • Loring SH, O'Donnell CR, Behazin N et al. Esophageal pressures in acute lung injury-do they represent artifact or useful information about transpulmonary pressure, chest wall mechanics, and lung stress? J. Appl. Physiol. 108(3), 515-522 (2010).
    • (2010) J. Appl. Physiol. , vol.108 , Issue.3 , pp. 515-522
    • Loring, S.H.1    O'Donnell, C.R.2    Behazin, N.3
  • 77
    • 56249128276 scopus 로고    scopus 로고
    • Mechanical ventilation guided by esophageal pressure in acute lung injury
    • Talmor D, Sarge T, Malhotra A et al. Mechanical ventilation guided by esophageal pressure in acute lung injury. N. Engl. J. Med. 359(20), 2095-2104 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.20 , pp. 2095-2104
    • Talmor, D.1    Sarge, T.2    Malhotra, A.3
  • 78
    • 28944445502 scopus 로고    scopus 로고
    • Tidal volume reduction in patients with acute lung injury when plateau pressures are not high
    • Hager DN, Krishnan JA, Hayden DL, Brower RG. Tidal volume reduction in patients with acute lung injury when plateau pressures are not high. Am. J. Respir. Crit. Care Med. 172(10), 1241-1245 (2005).
    • (2005) Am. J. Respir. Crit. Care Med. , vol.172 , Issue.10 , pp. 1241-1245
    • Hager, D.N.1    Krishnan, J.A.2    Hayden, D.L.3    Brower, R.G.4
  • 79
    • 48949102231 scopus 로고    scopus 로고
    • Lung stress and strain in acute respiratory distress syndrome: Good ideas for clinical management?
    • Brower RG, Hubmayr RD, Slutsky AS. Lung stress and strain in acute respiratory distress syndrome: good ideas for clinical management? Am. J. Respir. Crit. Care Med. 178(4), 323-324 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , Issue.4 , pp. 323-324
    • Brower, R.G.1    Hubmayr, R.D.2    Slutsky, A.S.3
  • 80
    • 34247562400 scopus 로고    scopus 로고
    • Determination of functional residual capacity by oxygen washin-washout: A validation study
    • Maisch S, Boehm SH, Weismann D et al. Determination of functional residual capacity by oxygen washin-washout: a validation study. Intensive Care Med. 33(5), 912-916 (2007).
    • (2007) Intensive Care Med. , vol.33 , Issue.5 , pp. 912-916
    • Maisch, S.1    Boehm, S.H.2    Weismann, D.3
  • 81
    • 76349084039 scopus 로고    scopus 로고
    • Validation and clinical feasibility of nitrogen washin/ washout functional residual capacity measurements in children
    • Olegard C, Sondergaard S, Palsson J, Lundin S, Stenqvist O. Validation and clinical feasibility of nitrogen washin/ washout functional residual capacity measurements in children. Acta Anaesthesiol. Scand. 54(3), 370-376 (2010).
    • (2010) Acta Anaesthesiol. Scand. , vol.54 , Issue.3 , pp. 370-376
    • Olegard, C.1    Sondergaard, S.2    Palsson, J.3    Lundin, S.4    Stenqvist, O.5
  • 82
    • 0016282065 scopus 로고
    • Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure
    • Webb HH, Tierney DF. Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am. Rev. Resp. Dis. 110(5), 556-565 (1974).
    • (1974) Am. Rev. Resp. Dis. , vol.110 , Issue.5 , pp. 556-565
    • Webb, H.H.1    Tierney, D.F.2
  • 83
    • 0017109414 scopus 로고
    • Lung distensibility. The static pressure-volume curve of the lungs and its use in clinical assessment
    • Gibson GJ, Pride NB. Lung distensibility. The static pressure-volume curve of the lungs and its use in clinical assessment. Br. J. Dis. Chest 70(3), 143-184 (1976).
    • (1976) Br. J. Dis. Chest , vol.70 , Issue.3 , pp. 143-184
    • Gibson, G.J.1    Pride, N.B.2
  • 84
    • 33646546653 scopus 로고    scopus 로고
    • Customizing lung-protective mechanical ventilation strategies
    • Hager DN, Brower RG. Customizing lung-protective mechanical ventilation strategies. Crit. Care Med. 34(5), 1554-1555 (2006).
    • (2006) Crit. Care Med. , vol.34 , Issue.5 , pp. 1554-1555
    • Hager, D.N.1    Brower, R.G.2
  • 85
    • 0000973961 scopus 로고
    • Topography of esophageal pressure as a function of posture in man
    • Milic-Emili J, Mead J, Turner JM. Topography of esophageal pressure as a function of posture in man. J. Appl. Physiol. 19, 212-216 (1964).
    • (1964) J. Appl. Physiol. , vol.19 , pp. 212-216
    • Milic-Emili, J.1    Mead, J.2    Turner, J.M.3
  • 86
    • 33644485934 scopus 로고
    • Improved technique for estimating pleural pressure from esophageal balloons
    • Milic-Emili J, Mead J, Turner JM, Glauser EM. Improved technique for estimating pleural pressure from esophageal balloons. J. Appl. Physiol. 19, 207-211 (1964).
    • (1964) J. Appl. Physiol. , vol.19 , pp. 207-211
    • Milic-Emili, J.1    Mead, J.2    Turner, J.M.3    Glauser, E.M.4
  • 87
    • 33645801991 scopus 로고    scopus 로고
    • Volume-related and volume-independent effects of posture on esophageal and transpulmonary pressures in healthy subjects
    • Washko GR, O'Donnell CR, Loring SH. Volume-related and volume-independent effects of posture on esophageal and transpulmonary pressures in healthy subjects. J. Appl. Physiol. 100(3), 753-758 (2006).
    • (2006) J. Appl. Physiol. , vol.100 , Issue.3 , pp. 753-758
    • Washko, G.R.1    O'Donnell, C.R.2    Loring, S.H.3
  • 88
    • 77949628652 scopus 로고    scopus 로고
    • Is there a place for esophageal manometry in the care of patients with injured lungs?
    • Hubmayr RD. Is there a place for esophageal manometry in the care of patients with injured lungs? J. Appl. Physiol. 108, 481-482 (2010).
    • (2010) J. Appl. Physiol. , vol.108 , pp. 481-482
    • Hubmayr, R.D.1
  • 89
    • 67650152648 scopus 로고    scopus 로고
    • Targeting transpulmonary pressure to prevent ventilator induced lung injury
    • Sarge T, Talmor D. Targeting transpulmonary pressure to prevent ventilator induced lung injury. Minerva Anestesiol. 75(5), 293-299 (2009).
    • (2009) Minerva Anestesiol. , vol.75 , Issue.5 , pp. 293-299
    • Sarge, T.1    Talmor, D.2
  • 90
    • 65249123181 scopus 로고    scopus 로고
    • Feasibility of quantifying the mechanical properties of lung parenchyma in a small-animal model using 1H magnetic resonance elastography (MRE)
    • McGee KP, Hubmayr RD, Levin D, Ehman RL. Feasibility of quantifying the mechanical properties of lung parenchyma in a small-animal model using 1H magnetic resonance elastography (MRE). J. Magn. Reson. Imaging 29(4), 838-845 (2009).
    • (2009) J. Magn. Reson. Imaging , vol.29 , Issue.4 , pp. 838-845
    • McGee, K.P.1    Hubmayr, R.D.2    Levin, D.3    Ehman, R.L.4
  • 91
    • 37549034251 scopus 로고    scopus 로고
    • MR elastography of the lung with hyperpolarized 3He
    • McGee KP, Hubmayr RD, Ehman RL. MR elastography of the lung with hyperpolarized 3He. Magn. Reson. Med. 59(1), 14-18 (2008).
    • (2008) Magn. Reson. Med. , vol.59 , Issue.1 , pp. 14-18
    • McGee, K.P.1    Hubmayr, R.D.2    Ehman, R.L.3
  • 93
    • 77953258775 scopus 로고    scopus 로고
    • Preliminary study of human lung elasticity with the noninvasive surface wave technique
    • Presented at. CA USA, 2-4 June
    • Zhang X, Qiang B, Hubmayr R et al. Preliminary study of human lung elasticity with the noninvasive surface wave technique. Presented at: UFFC Meeting 2010. CA, USA, 2-4 June 2010.
    • (2010) UFFC Meeting 2010
    • Zhang, X.1    Qiang, B.2    Hubmayr, R.3
  • 94
    • 0036707825 scopus 로고    scopus 로고
    • Effects of fixatives on function of pulmonary surfactant
    • Bachofen H, Gerber U, Schurch S. Effects of fixatives on function of pulmonary surfactant. J. Appl. Physiol. 93(3), 911-916 (2002).
    • (2002) J. Appl. Physiol. , vol.93 , Issue.3 , pp. 911-916
    • Bachofen, H.1    Gerber, U.2    Schurch, S.3
  • 95
    • 0026316716 scopus 로고
    • Alveolar septal folding and lung inflation history
    • Oldmixon EH, Hoppin FG Jr. Alveolar septal folding and lung inflation history. J. Appl. Physiol. 71(6), 2369-2379 (1991).
    • (1991) J. Appl. Physiol. , vol.71 , Issue.6 , pp. 2369-2379
    • Oldmixon, E.H.1    Hoppin Jr., F.G.2
  • 96
    • 0033968262 scopus 로고    scopus 로고
    • The effects of mechanical forces on lung functions
    • Wirtz HR, Dobbs LG. The effects of mechanical forces on lung functions. Respir. Physiol. 119(1), 1-17 (2000).
    • (2000) Respir. Physiol. , vol.119 , Issue.1 , pp. 1-17
    • Wirtz, H.R.1    Dobbs, L.G.2
  • 97
    • 34548418468 scopus 로고    scopus 로고
    • Alveolar expansion imaged by optical sectioning microscopy
    • Perlman CE, Bhattacharya J. Alveolar expansion imaged by optical sectioning microscopy. J. Appl. Physiol. 103(3), 1037-1044 (2007).
    • (2007) J. Appl. Physiol. , vol.103 , Issue.3 , pp. 1037-1044
    • Perlman, C.E.1    Bhattacharya, J.2
  • 98
    • 0032742793 scopus 로고    scopus 로고
    • The mechanism of lung volume change during mechanical ventilation
    • Carney DE, Bredenberg CE, Schiller HJ et al. The mechanism of lung volume change during mechanical ventilation. Am. J. Respir. Crit. Care Med. 160(5 Pt 1), 1697-1702 (1999).
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.5 PART 1 , pp. 1697-1702
    • Carney, D.E.1    Bredenberg, C.E.2    Schiller, H.J.3
  • 99
    • 0037389442 scopus 로고    scopus 로고
    • Alveolar inflation during generation of a quasi-static pressure/volume curve in the acutely injured lung
    • Schiller HJ, Steinberg J, Halter J et al. Alveolar inflation during generation of a quasi-static pressure/volume curve in the acutely injured lung. Crit. Care Med. 31(4), 1126-1133 (2003).
    • (2003) Crit. Care Med. , vol.31 , Issue.4 , pp. 1126-1133
    • Schiller, H.J.1    Steinberg, J.2    Halter, J.3
  • 100
    • 0038128195 scopus 로고    scopus 로고
    • Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/ derecruitment
    • Halter JM, Steinberg JM, Schiller HJ et al. Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/ derecruitment. Am. J. Respir. Crit. Care Med. 167(12), 1620-1626 (2003).
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , Issue.12 , pp. 1620-1626
    • Halter, J.M.1    Steinberg, J.M.2    Schiller, H.J.3
  • 101
    • 0036884055 scopus 로고    scopus 로고
    • Tidal volume increases do not affect alveolar mechanics in normal lung but cause alveolar overdistension and exacerbate alveolar instability after surfactant deactivation
    • Steinberg J, Schiller HJ, Halter JM et al. Tidal volume increases do not affect alveolar mechanics in normal lung but cause alveolar overdistension and exacerbate alveolar instability after surfactant deactivation. Crit. Care Med. 30(12), 2675-2683 (2002).
    • (2002) Crit. Care Med. , vol.30 , Issue.12 , pp. 2675-2683
    • Steinberg, J.1    Schiller, H.J.2    Halter, J.M.3
  • 102
    • 0035016096 scopus 로고    scopus 로고
    • Altered alveolar mechanics in the acutely injured lung
    • Schiller HJ, McCann UG 2nd, Carney DE et al. Altered alveolar mechanics in the acutely injured lung. Crit. Care Med. 29(5), 1049-1055 (2001).
    • (2001) Crit. Care Med. , vol.29 , Issue.5 , pp. 1049-1055
    • Schiller, H.J.1    McCann II, U.G.2    Carney, D.E.3
  • 103
    • 34447526510 scopus 로고    scopus 로고
    • Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics
    • Pavone LA, Albert S, Carney D et al. Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics. Crit. Care 11(3), R64 (2007).
    • (2007) Crit. Care , vol.11 , Issue.3
    • Pavone, L.A.1    Albert, S.2    Carney, D.3
  • 104
    • 53449087005 scopus 로고    scopus 로고
    • Atomic force microscope elastography reveals phenotypic differences in alveolar cell stiffness
    • Azeloglu EU, Bhattacharya J, Costa KD. Atomic force microscope elastography reveals phenotypic differences in alveolar cell stiffness. J. Appl. Physiol. 105(2), 652-661 (2008).
    • (2008) J. Appl. Physiol. , vol.105 , Issue.2 , pp. 652-661
    • Azeloglu, E.U.1    Bhattacharya, J.2    Costa, K.D.3
  • 105
    • 0034972604 scopus 로고    scopus 로고
    • Mechanical properties of alveolar epithelial cells in culture
    • Berrios JC, Schroeder MA, Hubmayr RD. Mechanical properties of alveolar epithelial cells in culture. J. Appl. Physiol. 91(1), 65-73 (2001).
    • (2001) J. Appl. Physiol. , vol.91 , Issue.1 , pp. 65-73
    • Berrios, J.C.1    Schroeder, M.A.2    Hubmayr, R.D.3
  • 106
    • 0029332186 scopus 로고
    • Mechanoreception at the cellular level: The detection, interpretation, and diversity of responses to mechanical signals
    • Banes AJ, Tsuzaki M, Yamamoto J et al. Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochem. Cell. Biol. 73(7-8), 349-365 (1995).
    • (1995) Biochem. Cell. Biol. , vol.73 , pp. 7-8
    • Banes, A.J.1    Tsuzaki, M.2    Yamamoto, J.3
  • 107
    • 0027431295 scopus 로고
    • Role of tidal volume FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation
    • Dreyfuss D, Saumon G. Role of tidal volume, FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation. Am. Rev. Resp. Dis. 148(5), 1194-1203 (1993).
    • (1993) Am. Rev. Resp. Dis. , vol.148 , Issue.5 , pp. 1194-1203
    • Dreyfuss, D.1    Saumon, G.2
  • 108
    • 0019961762 scopus 로고
    • Lung inflation, lung solute permeability, and alveolar edema
    • Egan EA. Lung inflation, lung solute permeability, and alveolar edema. J. Appl. Physiol. 53(1), 121-125 (1982).
    • (1982) J. Appl. Physiol. , vol.53 , Issue.1 , pp. 121-125
    • Egan, E.A.1
  • 109
    • 0037447358 scopus 로고    scopus 로고
    • Ventilator-induced cell wounding and repair in the intact lung
    • Gajic O, Lee J, Doerr CH et al. Ventilator-induced cell wounding and repair in the intact lung. Am. J. Respir. Crit. Care Med. 167(8), 1057-1063 (2003).
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , Issue.8 , pp. 1057-1063
    • Gajic, O.1    Lee, J.2    Doerr, C.H.3
  • 110
    • 0346874411 scopus 로고    scopus 로고
    • Quantification of stretch-induced cytoskeletal remodeling in vascular endothelial cells by image processing
    • Yoshigi M, Clark EB, Yost HJ. Quantification of stretch-induced cytoskeletal remodeling in vascular endothelial cells by image processing. Cytometry A 55(2), 109-118 (2003).
    • (2003) Cytometry A , vol.55 , Issue.2 , pp. 109-118
    • Yoshigi, M.1    Clark, E.B.2    Yost, H.J.3
  • 111
    • 0028342810 scopus 로고
    • Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension
    • Wang N, Ingber DE. Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. Biophys. J. 66(6), 2181-2189 (1994).
    • (1994) Biophys. J. , vol.66 , Issue.6 , pp. 2181-2189
    • Wang, N.1    Ingber, D.E.2
  • 112
    • 1842504023 scopus 로고    scopus 로고
    • Towards a regional approach to cell mechanics
    • Heidemann SR, Wirtz D. Towards a regional approach to cell mechanics. Trends Cell Biol. 14(4), 160-166 (2004).
    • (2004) Trends Cell Biol. , vol.14 , Issue.4 , pp. 160-166
    • Heidemann, S.R.1    Wirtz, D.2
  • 113
    • 0034065138 scopus 로고    scopus 로고
    • Partners in protection: Interdependence of cytoskeleton and plasma membrane in adaptations to applied forces
    • Ko KS, McCulloch CA. Partners in protection: interdependence of cytoskeleton and plasma membrane in adaptations to applied forces. J. Membr. Biol. 174(2), 85-95 (2000).
    • (2000) J. Membr. Biol. , vol.174 , Issue.2 , pp. 85-95
    • Ko, K.S.1    McCulloch, C.A.2
  • 114
    • 0036840592 scopus 로고    scopus 로고
    • Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure
    • Vlahakis NE, Schroeder MA, Pagano RE, Hubmayr RD. Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. Am. J. Respir. Crit. Care Med. 166(9), 1282-1289 (2002).
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , Issue.9 , pp. 1282-1289
    • Vlahakis, N.E.1    Schroeder, M.A.2    Pagano, R.E.3    Hubmayr, R.D.4
  • 116
    • 54049115030 scopus 로고    scopus 로고
    • Cell wounding and repair in ventilator injured lungs
    • Oeckler RA, Hubmayr RD. Cell wounding and repair in ventilator injured lungs. Respir. Physiol. Neurobiol. 163(1-3), 44-53 (2008).
    • (2008) Respir. Physiol. Neurobiol. , vol.163 , pp. 1-3
    • Oeckler, R.A.1    Hubmayr, R.D.2
  • 117
    • 0042978564 scopus 로고    scopus 로고
    • Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice
    • Chakrabarti S, Kobayashi KS, Flavell RA et al. Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice. J. Cell Biol. 162(4), 543-549 (2003).
    • (2003) J. Cell Biol. , vol.162 , Issue.4 , pp. 543-549
    • Chakrabarti, S.1    Kobayashi, K.S.2    Flavell, R.A.3
  • 118
    • 0030981335 scopus 로고    scopus 로고
    • Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
    • Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J. Clin. Invest. 99(5), 944-952 (1997).
    • (1997) J. Clin. Invest. , vol.99 , Issue.5 , pp. 944-952
    • Tremblay, L.1    Valenza, F.2    Ribeiro, S.P.3    Li, J.4    Slutsky, A.S.5
  • 119
    • 0037394450 scopus 로고    scopus 로고
    • Molecular mechanisms of lung cell activation induced by cyclic stretch
    • Pugin J. Molecular mechanisms of lung cell activation induced by cyclic stretch. Crit. Care Med. 31(4 Suppl.), S200-S206 (2003).
    • (2003) Crit. Care Med. , vol.31 , Issue.4 SUPPL.
    • Pugin, J.1
  • 120
    • 0033781864 scopus 로고    scopus 로고
    • Invited review: Mechanisms of ventilator-induced lung injury: A perspective
    • Dos Santos CC, Slutsky AS. Invited review: mechanisms of ventilator-induced lung injury: a perspective. J. Appl. Physiol. 89(4), 1645-1655 (2000).
    • (2000) J. Appl. Physiol. , vol.89 , Issue.4 , pp. 1645-1655
    • Dos Santos, C.C.1    Slutsky, A.S.2
  • 123
    • 0030740049 scopus 로고    scopus 로고
    • High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma
    • Berg JT, Fu Z, Breen EC et al. High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma. J. Appl. Physiol. 83(1), 120-128 (1997).
    • (1997) J. Appl. Physiol. , vol.83 , Issue.1 , pp. 120-128
    • Berg, J.T.1    Fu, Z.2    Breen, E.C.3
  • 124
    • 0032429614 scopus 로고    scopus 로고
    • Activation of human macrophages by mechanical ventilation in vitro
    • Pugin J, Dunn I, Jolliet P et al. Activation of human macrophages by mechanical ventilation in vitro. Am. J. Physiol. 275(6 Pt 1), L1040-L1050 (1998).
    • (1998) Am. J. Physiol. , vol.275 , Issue.6 PART 1
    • Pugin, J.1    Dunn, I.2    Jolliet, P.3
  • 125
    • 0032768453 scopus 로고    scopus 로고
    • Stretch induces cytokine release by alveolar epithelial cells in vitro
    • Vlahakis NE, Schroeder MA, Limper AH, Hubmayr RD. Stretch induces cytokine release by alveolar epithelial cells in vitro. Am. J. Physiol. 277(1 Pt 1), L167-L173 (1999).
    • (1999) Am. J. Physiol. , vol.277 , Issue.1 PART 1
    • Vlahakis, N.E.1    Schroeder, M.A.2    Limper, A.H.3    Hubmayr, R.D.4
  • 126
    • 0042344995 scopus 로고    scopus 로고
    • Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-κB-inducing kinases
    • Li LF, Ouyang B, Choukroun G et al. Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-κB-inducing kinases. Am. J. Physiol. 285(2), L464-L475 (2003).
    • (2003) Am. J. Physiol. , vol.285 , Issue.2
    • Li, L.F.1    Ouyang, B.2    Choukroun, G.3
  • 127
    • 23044457754 scopus 로고    scopus 로고
    • Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits
    • D'Angelo E, Pecchiari M, Della Valle P, Koutsoukou A, Milic-Emili J. Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits. J. Appl. Physiol. 99(2), 433-444 (2005).
    • (2005) J. Appl. Physiol. , vol.99 , Issue.2 , pp. 433-444
    • D'Angelo, E.1    Pecchiari, M.2    Della Valle, P.3    Koutsoukou, A.4    Milic-Emili, J.5
  • 129
    • 23044432610 scopus 로고    scopus 로고
    • Ventilator-induced lung injury without biotrauma?
    • Hubmayr RD. Ventilator-induced lung injury without biotrauma? J. Appl. Physiol. 99(2), 384-385 (2005).
    • (2005) J. Appl. Physiol. , vol.99 , Issue.2 , pp. 384-385
    • Hubmayr, R.D.1
  • 130
    • 0004539015 scopus 로고    scopus 로고
    • Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients
    • Brower RG, Shanholtz CB, Fessler HE et al. Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients. Crit. Care Med. 27(8), 1492-1498 (1999).
    • (1999) Crit. Care Med. , vol.27 , Issue.8 , pp. 1492-1498
    • Brower, R.G.1    Shanholtz, C.B.2    Fessler, H.E.3
  • 131
    • 0032484918 scopus 로고    scopus 로고
    • Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome
    • Pressure- and Volume-Limited Ventilation Strategy Group
    • Stewart TE, Meade MO, Cook DJ et al. Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. Pressure- and Volume-Limited Ventilation Strategy Group. N. Engl. J. Med. 338(6), 355-361 (1998).
    • (1998) N. Engl. J. Med. , vol.338 , Issue.6 , pp. 355-361
    • Stewart, T.E.1    Meade, M.O.2    Cook, D.J.3
  • 132
    • 0032484956 scopus 로고    scopus 로고
    • Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome
    • Amato MB, Barbas CS, Medeiros DM et al. Effect of a protective- ventilation strategy on mortality in the acute respiratory distress syndrome. N. Engl. J. Med. 338(6), 347-354 (1998).
    • (1998) N. Engl. J. Med. , vol.338 , Issue.6 , pp. 347-354
    • Amato, M.B.1    Barbas, C.S.2    Medeiros, D.M.3
  • 133
    • 4444364798 scopus 로고    scopus 로고
    • Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation
    • Gajic O, Dara SI, Mendez JL et al. Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit. Care Med. 32(9), 1817-1824 (2004).
    • (2004) Crit. Care Med. , vol.32 , Issue.9 , pp. 1817-1824
    • Gajic, O.1    Dara, S.I.2    Mendez, J.L.3
  • 134
    • 37549032746 scopus 로고    scopus 로고
    • Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury
    • Wolthuis EK, Choi G, Dessing MC et al. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. Anesthesiology 108(1), 46-54 (2008).
    • (2008) Anesthesiology , vol.108 , Issue.1 , pp. 46-54
    • Wolthuis, E.K.1    Choi, G.2    Dessing, M.C.3
  • 135
    • 39149096865 scopus 로고    scopus 로고
    • Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury
    • Determann RM, Wolthuis EK, Choi G et al. Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury. Am. J. Physiol. 294(2), L344-L350 (2008).
    • (2008) Am. J. Physiol. , vol.294 , Issue.2
    • Determann, R.M.1    Wolthuis, E.K.2    Choi, G.3
  • 136
    • 34249698734 scopus 로고    scopus 로고
    • What tidal volumes should be used in patients without acute lung injury?
    • Schultz MJ, Haitsma JJ, Slutsky AS, Gajic O: What tidal volumes should be used in patients without acute lung injury? Anesthesiology 106(6), 1226-1231 (2007).
    • (2007) Anesthesiology , vol.106 , Issue.6 , pp. 1226-1231
    • Schultz, M.J.1    Haitsma, J.J.2    Slutsky, A.S.3    Gajic, O.4
  • 137
    • 33745272559 scopus 로고    scopus 로고
    • Hypercapnia: Permissive and therapeutic
    • Kavanagh BP, Laffey JG. Hypercapnia: permissive and therapeutic. Minerva Anestesiol. 72(6), 567-576 (2006).
    • (2006) Minerva Anestesiol. , vol.72 , Issue.6 , pp. 567-576
    • Kavanagh, B.P.1    Laffey, J.G.2
  • 139
    • 0033539362 scopus 로고    scopus 로고
    • Carbon dioxide and the critically ill - Too little of a good thing?
    • Laffey JG, Kavanagh BP. Carbon dioxide and the critically ill - too little of a good thing? Lancet 354(9186), 1283-1286 (1999).
    • (1999) Lancet , vol.354 , Issue.9186 , pp. 1283-1286
    • Laffey, J.G.1    Kavanagh, B.P.2
  • 140
    • 0024264995 scopus 로고
    • Acute respiratory failure following pharmacologically induced hyperventilation: An experimental animal study
    • Mascheroni D, Kolobow T, Fumagalli R et al. Acute respiratory failure following pharmacologically induced hyperventilation: an experimental animal study. Intensive Care Med. 15(1), 8-14 (1988).
    • (1988) Intensive Care Med. , vol.15 , Issue.1 , pp. 8-14
    • Mascheroni, D.1    Kolobow, T.2    Fumagalli, R.3
  • 141
    • 39049142106 scopus 로고    scopus 로고
    • Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: A randomized controlled trial
    • Meade MO, Cook DJ, Guyatt GH et al. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 299(6), 637-645 (2008).
    • (2008) JAMA , vol.299 , Issue.6 , pp. 637-645
    • Meade, M.O.1    Cook, D.J.2    Guyatt, G.H.3
  • 142
    • 33846307424 scopus 로고    scopus 로고
    • Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome
    • Terragni PP, Rosboch G, Tealdi A et al. Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 175(2), 160-166 (2007).
    • (2007) Am. J. Respir. Crit. Care Med. , vol.175 , Issue.2 , pp. 160-166
    • Terragni, P.P.1    Rosboch, G.2    Tealdi, A.3
  • 143
    • 18144420780 scopus 로고    scopus 로고
    • Effects of high versus low positive end-expiratory pressures in acute respiratory distress syndrome
    • Grasso S, Fanelli V, Cafarelli A et al. Effects of high versus low positive end-expiratory pressures in acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 171(9), 1002-1008 (2005).
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , Issue.9 , pp. 1002-1008
    • Grasso, S.1    Fanelli, V.2    Cafarelli, A.3
  • 144
    • 39049161097 scopus 로고    scopus 로고
    • Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: A randomized controlled trial
    • Mercat A, Richard JC, Vielle B et al. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 299(6), 646-655 (2008).
    • (2008) JAMA , vol.299 , Issue.6 , pp. 646-655
    • Mercat, A.1    Richard, J.C.2    Vielle, B.3
  • 145
    • 35348942240 scopus 로고    scopus 로고
    • ARDSnet ventilatory protocol and alveolar hyperinflation: Role of positive end-expiratory pressure
    • Grasso S, Stripoli T, De Michele M et al. ARDSnet ventilatory protocol and alveolar hyperinflation: role of positive end-expiratory pressure. Am. J. Respir. Crit. Care Med. 176(8), 761-767 (2007)
    • (2007) Am. J. Respir. Crit. Care Med. , vol.176 , Issue.8 , pp. 761-767
    • Grasso, S.1    Stripoli, T.2    De Michele, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.