Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits

Journal of Applied Physiology

Volumn 99, Issue 2, 2005, Pages 433-444

  D'Angelo, Edgardo ^a,e   Pecchiari, Matteo ^a   Della Valle, Patrizia ^b   Koutsoukou, Antonia ^c   Milic Emili, Joseph ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF ATHENS   (Greece)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

Exhaled vapor condensate; Interrupter resistance; Lung elastance; Proinflammatory cytokines; Viscoelasticity

Indexed keywords

ALBUMIN; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; BREATHING MECHANICS; CONTROLLED STUDY; EXPIRED AIR; LUNG COMPLIANCE; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG VOLUME; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RABBIT; TIDAL VOLUME; VISCOELASTICITY;

ANIMALS; EXHALATION; FORCED EXPIRATORY VOLUME; LUNG; NITRIC OXIDE; PNEUMONIA; PULMONARY GAS EXCHANGE; RABBITS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY MECHANICS;

EID: 23044457754     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01368.2004     Document Type: Article

References (43)

1. Bachofen H, Hildebrandt J, and Bachofen M. Pressure-volume curves of air- and liquid-filled excised lungs-surface tension in situ. J Appl Physiol 29: 422-431, 1970.
2. Barnes PJ and Belvisi MG. Nitric oxide and lung disease. Thorax 48: 1034-1043, 1993.
3. Bates JHT, Bacconier P, and Milic-Emili J. A theoretical analysis of interrupter technique for measuring respiratory mechanics. J Appl Physiol 64: 2204-2214, 1988.
4. Carlin RE, Ferrario L, Boyd JT, Camporesi EM, McGraw DJ, and Hakim TS. Determinants of nitric oxide in exhaled gas in the isolated rabbit lung. Am J Respir Crit Care Med 155: 922-927, 1997.
5. Cheng KC, Zeng H, and Slutsky AS. Ventilation with negative airway pressure induces a cytokine response in isolated mouse lung. Anesth Analg 94: 1577-1582, 2002.
6. Chu EK, Whitehead T, and Slutsky AS. Effects of cyclic opening and closing at low- and high-volume ventilation on bronchoalveolar lavage cytokines. Crit Care Med 32: 168-174, 2004.
7. Cremona G, Higenbottam T, Takao M, Hall L, and Bower EA. Exhaled nitric oxide in isolated pig lungs. J Appl Physiol 78: 59-63, 1995.
8. D'Angelo E, Bonanni MV, Michelini S, and Agostoni E. Topography of the pleural surface pressure in rabbits and dogs. Respir Physiol 8: 204-229, 1970.
9. D'Angelo E. Stress-strain relationships during uniform and non-uniform expansion of isolated lungs. Respir Physiol 23: 87-107, 1975.
10. D'Angelo E, Calderini E, Torri G, Robatto FM, Bono D, and Milic-Emili J. Respiratory mechanics in anesthetized paralyzed humans: effects of flow, volume, and time. J Appl Physiol 67: 2556-2564, 1989.
11. D'Angelo E, Pecchiari M, Baraggia P, Saetta M, Balestro E, and Milic-Emili J. Low-volume ventilation causes peripheral airway injury and increased airway resistance in normal rabbits. J Appl Physiol 92: 949-956, 2002.
12. D'Angelo E, Pecchiari M, Saetta M, Balestro E, and Milic-Emili J. Dependence of lung imjury on inflation rate during low-volume ventilation in normal open-chest rabbits. J Appl Physiol 97: 260-268, 2004.
13. Delgado M, Munoz-Elias EJ, Gomariz RP, and Ganea D. Vasoactive intestinal peptide and pituitary denylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-κB and IFN regulatory factor 1 activation. J Immunol 162: 4685-4696, 1999.
14. Dos Santos CC and Slutsky AS. Cellular responses to mechanical stress. Invited Review: Mechanisms of ventilator-induced lung injury: a perspective. J Appl Physiol 89: 1645-1655, 2000.
15. Forsberg S, Ludwigs U, and Hedenstierna G. Effects of ventilatory pattern on exhaled nitric oxide in mechanically ventilated rabbits. Acta Anesthesiol Scand 43: 464-469, 1999.
16. Glaister DH, Schroter RC, Sudlow MF, and Milic-Emili J. Transpulmonary pressure gradient and ventilation distribution in excised lungs. Respir Physiol 17: 365-385, 1973.
17. Gustafsson LE, Leone AM, Persson MG, Wiklund NP, and Moncada S. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. Biochem Biophys Res Commun 181: 852-857, 1991.
18. Haitsma JJ, Uhlig S, Göggel R, Verbrugge SJ, Lachmann U, and Lachmann B. Ventilator-induced lung injury leads to loss of alveolar and systemic compartimentalization of tumor necrosis factor-α. Intensive Care Med 26: 1515-1522, 2000.
19. Hughes JMB, Rosenzweig DY, and Kivitz PB. Site of airway closure in excised dog lungs: histologic demonstration. J Appl Physiol 29: 340-344, 1970.
20. Hunt JF, Fang K, Malik R, Snyder A, Malhotra N, Platts-Mills TAE, and Gaston B. Endogenous airway acidification. Am J Respir Crit Care Med 161: 694-699, 2000.
21. Kharitonov SA, Sapienza MM, Chung KF, and Barnes PJ. Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma. Eur Respir J 14: 1023-1027, 1999.
22. Maniscalco M, Vatrella A, Cremona G, Carratù L, and Sofia M. Exhaled nitric oxide after inhalation of isotonic and hypotonic solutions in healthy subjects. Clin Sci (Colch) 101: 645-650, 2001.
23. 2 and prostacyclin. Pharmacol Rev 30: 293-331, 1979.
24. Munford RS and Pugin J. Normal responses to injury prevent systemic inflammation and can be immunosuppressive. Am J Respir Crit Care Med 163: 316-321, 2001.
25. Muscedere JG, Mullen JBM, Gan K, Bryan AC, and Slutsky AS. Tidal ventilation at low airway pressure can augment lung injury. Am J Respir Crit Care Med 149: 1327-1334, 1994.
26. Nadel JA. Decreased neutral endopeptidases: possible role in inflammatory diseases of airways. Lung 168: 123-127, 1990.
27. Persson MG, Wiklund NP, and Gustafsson LE. Endogenous nitric oxide in single exhalations and the change during exercise. Am J Respir Crit Care Med 148: 1210-1214, 1993.
28. Proud D. Kinins as mediators of lung disease. In: The Lung, edited by Crystal RG, West JB, Weibel ER, and Barnes PJ. New York: Lippincott-Raven, 1997, p. 89-101.
29. Pugin J, Dunn I, Jolliet P, Tassaux D, Magnetat JL, Nicod LP, and Chevrolet JC. Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol Lung Cell Mol Physiol 275: L1040-L1050, 1998.
30. Ricard JD, Dreyfuss D, and Saumon G. Production of inflammatory cytokines in ventilator-induced lung injury: a reappraisal. Am J Respir Crit Care Med 163: 1176-1180, 2001.
31. Robertson B. Lung surfactant. In: Pulmonary Surfactant, edited by Robertson B, Van Goulde L, and Batenburg J. Amsterdam: Elsevier, 1984, p. 132-147.
32. Rolfe MW, Kunkel SL, Standiford TJ, Chensue SW, Allen RM, Evanoff HL, Phan SH, and Strieter RM. Pulmonary fibroblast expression of interleukin-8: a model for alveolar macrophage-derived cytokine networking. Am J Respir Cell Mol Biol 5: 493-501, 1991.
33. Said SI. Vasoactive intestinal peptide and nitric oxide: divergent roles in relation to tissue injury. Ann NY Acad Sci 805: 379-387, 1996.
34. Salazar E and Knowles JH. An analysis of the pressure-volume characteristics of the lung. J Appl Physiol 19: 97-104, 1964.
35. Strömberg S, Lönnqvist PA, Persson MG, and Gustafsson LE. Lung distension and carbon dioxide affect pulmonary nitric oxide formation in the anaesthetized rabbit. Acta Physiol Scand 159: 59-67, 1997.
36. Taskar V, John J, Evander E, Robertson B, and Jonson B. Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion. Am J Respir Crit Care Med 155: 313-320, 1997.
37. Tracey KJ, Vlassara H, and Cerami A. Cachectin/tumor necrosis factor. Lancet 1: 1122-1126, 1989.
38. Tremblay L, Valenza F, Ribeiro S, Li J, and Slutsky AS. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 99: 944-952, 1997.
39. Tschumperlin DJ, Oswari J, and Marguleis AS. Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude. Am J Respir Crit Care Med 162: 357-362, 2000.
40. Uddman R, Sundler F, Cardell LO, and Luts A. Neuropeptides in the lung. In: The Lung, edited by Crystal RG, West JB, Weibel ER, and Barnes PJ. New York: Lippincott-Raven, 1997, p. 103-115.
41. Verbrugge SJC, Uhlig S, Neggers SJCMM, Martin C, Held HD, Haitsma JJ, and Lachmann B. Different ventilation strategies affect lung function but do not increase tumor necrosis factor-α and prostacyclin production in lavaged rat lungs in vivo. Anesthesiology 91: 1834-1843, 1999.
42. Vlahakis NE, Schroder MA, Limper AH, and Hubmayr RD. Stretch induced cytokine release by alveolar epithelial cells in vitro. Am J Physiol Lung Cell Mol Physiol 277: L167-L173, 1999.
43. Waage A. Production and clearance of tumor necrosis factor in rats exposed to endotoxin and dexamethasone. Clin Immunol Immunopathol 45: 348-355, 1987.