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Volumn 9, Issue 1, 2003, Pages 2-8

Response of alveolar cells to mechanical stress

Author keywords

Alveolar cells; Deformation; Lung injury; Mechanotransduction; Surfactant

Indexed keywords

CALCIUM; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; PARATHYROID HORMONE RELATED PROTEIN; SURFACTANT;

EID: 0037308350     PISSN: 10705295     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075198-200302000-00002     Document Type: Review
Times cited : (76)

References (66)
  • 1
    • 0016282065 scopus 로고
    • Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: Protection by positive end-expiratory pressure
    • Webb, HH, Tierney DF: Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: protection by positive end-expiratory pressure. Am Rev Respir Dis 1974, 110:556-565.
    • (1974) Am Rev Respir Dis , vol.110 , pp. 556-565
    • Webb, H.H.1    Tierney, D.F.2
  • 2
    • 0031942649 scopus 로고    scopus 로고
    • Ventilator-induced lung injury: Lessons from experimental studies
    • Dreyfuss D, Saumon G: Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998, 157:294-323.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 294-323
    • Dreyfuss, D.1    Saumon, G.2
  • 3
    • 0343893748 scopus 로고    scopus 로고
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
    • The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000, 342:1301-1308.
    • (2000) N Engl J Med , vol.342 , pp. 1301-1308
  • 4
    • 0036084003 scopus 로고    scopus 로고
    • Ventilation-induced lung injury and mechanotransduction: Stretching it too far?
    • Uhlig S: Ventilation-induced lung injury and mechanotransduction: stretching it too far? Am J Physiol Lung Cell Mol Physiol 2002, 282:L892-L896. This review highlights an important perceptual approach to understanding mechanotransduction mechanisms that result in inflammation of the lung. The authors separate the potential causes of inflammation into those resulting from the disruption of alveolar cell membranes and those resulting from noninjurious cellular deformation. They also emphasize that vasculature responses can differ depending on the effects of shear stress and transluminal distending pressures.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Uhlig, S.1
  • 5
    • 0034801926 scopus 로고    scopus 로고
    • A system to impose prescribed homogenous strains on cultured cells
    • Waters CM, Glucksberg MR, Lautenschlager EP, et al.: A system to impose prescribed homogenous strains on cultured cells. J Appl Physiol 2001, 91:1600-1610.
    • (2001) J Appl Physiol , vol.91 , pp. 1600-1610
    • Waters, C.M.1    Glucksberg, M.R.2    Lautenschlager, E.P.3
  • 6
    • 0035008495 scopus 로고    scopus 로고
    • Validation of a new live cell strain system: Characterization of plasma membrane stress failure
    • Stroetz RW, Vlahakis NE, Walters BJ, et al.: Validation of a new live cell strain system: characterization of plasma membrane stress failure. J Appl Physiol 2001, 90:2361-2370.
    • (2001) J Appl Physiol , vol.90 , pp. 2361-2370
    • Stroetz, R.W.1    Vlahakis, N.E.2    Walters, B.J.3
  • 8
    • 0024997680 scopus 로고
    • Spatial distribution of collagen and elastin fibers in the lungs
    • Mercer RR, Crapo JD: Spatial distribution of collagen and elastin fibers in the lungs. J Appl Physiol 1990, 69:756-765.
    • (1990) J Appl Physiol , vol.69 , pp. 756-765
    • Mercer, R.R.1    Crapo, J.D.2
  • 9
    • 0021860979 scopus 로고
    • Regional lung strain in dogs during deflation from total lung capacity
    • Rodarte JR, Hubmayr RD, Stamenovic D, et al.: Regional lung strain in dogs during deflation from total lung capacity. J Appl Physiol 1985, 58:164-172.
    • (1985) J Appl Physiol , vol.58 , pp. 164-172
    • Rodarte, J.R.1    Hubmayr, R.D.2    Stamenovic, D.3
  • 10
    • 0033061238 scopus 로고    scopus 로고
    • Alveolar epithelial surface area-volume relation in isolated rat lungs
    • Tschumperlin DJ, Margulies SS: Alveolar epithelial surface area-volume relation in isolated rat lungs. J Appl Physiol 1999, 86:2026-2033.
    • (1999) J Appl Physiol , vol.86 , pp. 2026-2033
    • Tschumperlin, D.J.1    Margulies, S.S.2
  • 11
    • 0031017220 scopus 로고    scopus 로고
    • Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    • Maniotis AJ, Chen CS, Ingber DE: Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A 1997, 94:849-854.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 849-854
    • Maniotis, A.J.1    Chen, C.S.2    Ingber, D.E.3
  • 12
    • 0034947294 scopus 로고    scopus 로고
    • Mechanical behavior in living cells consistent with the tensegrity model
    • Wang N, Naruse K, Stamenovic D, et al.: Mechanical behavior in living cells consistent with the tensegrity model. Proc Natl Acad Sci U S A 2001, 98:7765-7770.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7765-7770
    • Wang, N.1    Naruse, K.2    Stamenovic, D.3
  • 13
    • 0035516140 scopus 로고    scopus 로고
    • Transmembrane crosstalk between the extracellular matrix-cytoskeletal crosstalk
    • Geiger B, Bershadsky A, Pankov R, et al.: Transmembrane crosstalk between the extracellular matrix-cytoskeletal crosstalk. Nat Rev Mol Cell Biol 2001, 2:793-805.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 793-805
    • Geiger, B.1    Bershadsky, A.2    Pankov, R.3
  • 14
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • Dudek SM, Garcia JG: Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol 2001, 91:1487-1500.
    • (2001) J Appl Physiol , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.2
  • 15
    • 0033675578 scopus 로고    scopus 로고
    • Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury
    • Parker JC: Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury. J Appl Physiol 2000, 89:2241-2248.
    • (2000) J Appl Physiol , vol.89 , pp. 2241-2248
    • Parker, J.C.1
  • 16
    • 0031898295 scopus 로고    scopus 로고
    • Gadolinium prevents high airway pressure-induced permeability increases in isolated rat lung
    • Parker JC, Ivey CL, Tucker JA: Gadolinium prevents high airway pressure-induced permeability increases in isolated rat lung. J Appl Physiol 1998, 84:1113-1118.
    • (1998) J Appl Physiol , vol.84 , pp. 1113-1118
    • Parker, J.C.1    Ivey, C.L.2    Tucker, J.A.3
  • 17
    • 0032947845 scopus 로고    scopus 로고
    • Temporary disruption of the plasma membrane is required for c-fos expression in response to mechanical stress
    • Grembowicz KP, Sprague D, McNeil PL: Temporary disruption of the plasma membrane is required for c-fos expression in response to mechanical stress. Mol Biol Cell 1999, 10:1247-1257.
    • (1999) Mol Biol Cell , vol.10 , pp. 1247-1257
    • Grembowicz, K.P.1    Sprague, D.2    McNeil, P.L.3
  • 18
    • 0034644509 scopus 로고    scopus 로고
    • Signaling networks: The origins of cellular multitasking
    • Jordan JD, Landau EM, Iyengar R: Signaling networks: the origins of cellular multitasking. Cell 2000, 103:193-200.
    • (2000) Cell , vol.103 , pp. 193-200
    • Jordan, J.D.1    Landau, E.M.2    Iyengar, R.3
  • 19
    • 0033603352 scopus 로고    scopus 로고
    • Mechanotransduction in response to shear stress: Role of receptor tyrosine kinases, integrins and Shc
    • Chen KD, Li YS, Kim M, et al.: Mechanotransduction in response to shear stress: role of receptor tyrosine kinases, integrins and Shc. J Biol Chem 1999, 274:18393-18400.
    • (1999) J Biol Chem , vol.274 , pp. 18393-18400
    • Chen, K.D.1    Li, Y.S.2    Kim, M.3
  • 20
    • 0035983319 scopus 로고    scopus 로고
    • Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch
    • Oudin S, Pugin J: Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. Am J Respir Cell Mol Biol 2002, 27:107-114. Using a bronchial epithelial cell system, the authors demonstrate the importance of tyrosine kinase proteins in signaling the transcription of IL-8 messenger RNA after cyclic stretch. They demonstrate that the responding elements cyclic AMP responding element and activator protein 1 are activated, and, by using specific inhibitors, they showed that the production of IL-8 messenger RNA and the secretion of IL-8 protein were dependent on p38 and p44/42 MAPK pathways.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 107-114
    • Oudin, S.1    Pugin, J.2
  • 21
    • 0029616040 scopus 로고
    • Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-κB, in endothelial cells: Species and vascular bed diversity
    • Du W, Mills I, Sumpio BE: Cyclic strain causes heterogeneous induction of transcription factors, AP-1, CRE binding protein and NF-κB, in endothelial cells: species and vascular bed diversity. J Biomech 1995, 28:1485-1491.
    • (1995) J Biomech , vol.28 , pp. 1485-1491
    • Du, W.1    Mills, I.2    Sumpio, B.E.3
  • 24
    • 0032759944 scopus 로고    scopus 로고
    • Mechanical force-induced signal transduction in lung cells
    • Liu M, Tanswell AK, Post M: Mechanical force-induced signal transduction in lung cells. Am J Physiol 1999, 277:L667-L683.
    • (1999) Am J Physiol , vol.277
    • Liu, M.1    Tanswell, A.K.2    Post, M.3
  • 25
    • 0033781864 scopus 로고    scopus 로고
    • Invited review: Mechanisms of ventilator-induced lung injury: A perspective
    • Dos Santos CC, Slutsky AS: Invited review: Mechanisms of ventilator-induced lung injury: a perspective. J Appl Physiol 2000, 89:1645-1655.
    • (2000) J Appl Physiol , vol.89 , pp. 1645-1655
    • Dos Santos, C.C.1    Slutsky, A.S.2
  • 26
    • 0031738599 scopus 로고    scopus 로고
    • Phosphotyrosine phosphatase and tyrosine kinase inhibition modulate airway pressure-induced lung injury
    • Parker JC, Ivey CL, Tucker JA: Phosphotyrosine phosphatase and tyrosine kinase inhibition modulate airway pressure-induced lung injury. J Appl Physiol 1998, 85:1753-1761.
    • (1998) J Appl Physiol , vol.85 , pp. 1753-1761
    • Parker, J.C.1    Ivey, C.L.2    Tucker, J.A.3
  • 27
    • 0035076572 scopus 로고    scopus 로고
    • Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-κB and is blocked by steroids
    • Held HD, Boettcher S, Hamann L, et al.: Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-κB and is blocked by steroids. Am J Respir Crit Care Med 2001, 163:711-716.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 711-716
    • Held, H.D.1    Boettcher, S.2    Hamann, L.3
  • 28
    • 0032768453 scopus 로고    scopus 로고
    • Stretch induces cytokine release by alveolar epithelial cells in vitro
    • Vlahakis NE, Schroeder MA, Limper AH, et al.: Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol 1999, 277:L167-L173.
    • (1999) Am J Physiol , vol.277
    • Vlahakis, N.E.1    Schroeder, M.A.2    Limper, A.H.3
  • 29
    • 0032429614 scopus 로고    scopus 로고
    • Activation of human macrophages by mechanical ventilation in vitro
    • Pugin J, Dunn I, Jolliet P, et al.: Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol 1998, 275:L1040-L1050.
    • (1998) Am J Physiol , vol.275
    • Pugin, J.1    Dunn, I.2    Jolliet, P.3
  • 30
    • 0030981335 scopus 로고    scopus 로고
    • Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
    • Tremblay L, Valenza F, Ribeiro SP, et al.: Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997, 99:944-952.
    • (1997) J Clin Invest , vol.99 , pp. 944-952
    • Tremblay, L.1    Valenza, F.2    Ribeiro, S.P.3
  • 31
    • 0032823313 scopus 로고    scopus 로고
    • Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
    • Holtmann H, Winzen R, Holland P, et al.: Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol Cell Biol 1999, 19:6742-6753.
    • (1999) Mol Cell Biol , vol.19 , pp. 6742-6753
    • Holtmann, H.1    Winzen, R.2    Holland, P.3
  • 32
    • 0032778978 scopus 로고    scopus 로고
    • Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells
    • Quinn D, Tager A, Joseph PM, et al.: Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells. Chest 1999, 116(suppl):89S-90S.
    • (1999) Chest , vol.116 , Issue.SUPPL.
    • Quinn, D.1    Tager, A.2    Joseph, P.M.3
  • 33
    • 0033855335 scopus 로고    scopus 로고
    • Mechanical strain-induced proliferation and signaling in pulmonary epithelial H441 cells
    • Chess PR, Toia L, Finkelstein JN: Mechanical strain-induced proliferation and signaling in pulmonary epithelial H441 cells. Am J Physiol Lung Cell Mol Physiol 2000, 279:L43-L51.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Chess, P.R.1    Toia, L.2    Finkelstein, J.N.3
  • 34
    • 0036083814 scopus 로고    scopus 로고
    • Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells
    • Correa-Meyer E, Pesce L, Guerrero C, et al.: Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 2002, 282:L883-L891. The authors demonstrate for the first time that ERK1 and ERK2 can be activated by cyclic stretch in a G protein- and epidermal growth factor receptor-dependent fashion. This is a novel mechanotransduction pathway that is independent of the son of sevenless/growth factor receptor binding protein 2 classic MAPK pathway. In addition, they show that this signaling pathway does not involve stretch-activated calcium and sodium ion channels.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Correa-Meyer, E.1    Pesce, L.2    Guerrero, C.3
  • 35
    • 0033598131 scopus 로고    scopus 로고
    • Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways
    • Carpenter G: Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J Cell Biol 1999, 146:697-702.
    • (1999) J Cell Biol , vol.146 , pp. 697-702
    • Carpenter, G.1
  • 36
    • 0036080175 scopus 로고    scopus 로고
    • Cyclic stretch upregulates interleukin-8 and transforming growth factor-β1 production through a protein kinase C-dependent pathway in alveolar epithelial cells
    • Yamamoto H, Teramoto H, Uetani K, et al.: Cyclic stretch upregulates interleukin-8 and transforming growth factor-β1 production through a protein kinase C-dependent pathway in alveolar epithelial cells. Respirology 2002, 7:103-109.
    • (2002) Respirology , vol.7 , pp. 103-109
    • Yamamoto, H.1    Teramoto, H.2    Uetani, K.3
  • 37
    • 0034894865 scopus 로고    scopus 로고
    • Stretch induces a growth factor in alveolar cells via protein kinase
    • Yamamoto H, Teramoto H, Uetani K, et al.: Stretch induces a growth factor in alveolar cells via protein kinase. Respir Physiol 2001, 127:105-111.
    • (2001) Respir Physiol , vol.127 , pp. 105-111
    • Yamamoto, H.1    Teramoto, H.2    Uetani, K.3
  • 38
    • 0001609734 scopus 로고
    • Relation of volume history of lungs to respiratory mechanics in anesthetized dogs
    • Mead J, Collier C: Relation of volume history of lungs to respiratory mechanics in anesthetized dogs. J Appl Physiol 1959, 14:669-678.
    • (1959) J Appl Physiol , vol.14 , pp. 669-678
    • Mead, J.1    Collier, C.2
  • 39
    • 0020699638 scopus 로고
    • Morphologic evidence that large inflations of the lung stimulate secretion of surfactant
    • Massaro GD, Massaro D: Morphologic evidence that large inflations of the lung stimulate secretion of surfactant. Am Rev Respir Dis 1983, 127:235-236.
    • (1983) Am Rev Respir Dis , vol.127 , pp. 235-236
    • Massaro, G.D.1    Massaro, D.2
  • 40
    • 0020627815 scopus 로고
    • The release of surfactant in rat lung by brief periods of hyperventilation
    • Nicholas TE, Barr HA: The release of surfactant in rat lung by brief periods of hyperventilation. Respir Physiol 1983, 52:69-83.
    • (1983) Respir Physiol , vol.52 , pp. 69-83
    • Nicholas, T.E.1    Barr, H.A.2
  • 41
    • 0032847974 scopus 로고    scopus 로고
    • Mechanical ventilation of rat lung: Effect on surfactant forms
    • Savov J, Silbajoris R, Young SL: Mechanical ventilation of rat lung: effect on surfactant forms. Am J Physiol 1999, 277:L320-L326.
    • (1999) Am J Physiol , vol.277
    • Savov, J.1    Silbajoris, R.2    Young, S.L.3
  • 42
    • 0033962993 scopus 로고    scopus 로고
    • Effects of ventilation on the surtactant system in sepsis-induced lung injury
    • Malloy JL, Veldhuizen RA, Lewis JF: Effects of ventilation on the surtactant system in sepsis-induced lung injury. J Appl Physiol 2000, 88:401-408.
    • (2000) J Appl Physiol , vol.88 , pp. 401-408
    • Malloy, J.L.1    Veldhuizen, R.A.2    Lewis, J.F.3
  • 43
    • 0034911996 scopus 로고    scopus 로고
    • Mechanical ventilation of isolated septic rat lungs: Effects on surfactant and inflammatory cytokines
    • Nakamura T, Malloy J, McCaig L, et al.: Mechanical ventilation of isolated septic rat lungs: effects on surfactant and inflammatory cytokines. J Appl Physiol 2001, 91:811-820.
    • (2001) J Appl Physiol , vol.91 , pp. 811-820
    • Nakamura, T.1    Malloy, J.2    McCaig, L.3
  • 44
    • 0036089848 scopus 로고    scopus 로고
    • Mechanical ventilation of isolated rat lungs changes the structure and biophysical properties of surfactant
    • Veldhuizen RA, Welk B, Harbottle R, et al.: Mechanical ventilation of isolated rat lungs changes the structure and biophysical properties of surfactant. J Appl Physiol 2002, 92:1169-1175.
    • (2002) J Appl Physiol , vol.92 , pp. 1169-1175
    • Veldhuizen, R.A.1    Welk, B.2    Harbottle, R.3
  • 45
    • 0025605970 scopus 로고
    • Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells
    • Wirtz HR, Dobbs LG: Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells. Science 1990, 250:1266-1269.
    • (1990) Science , vol.250 , pp. 1266-1269
    • Wirtz, H.R.1    Dobbs, L.G.2
  • 46
    • 0035008472 scopus 로고    scopus 로고
    • Stretch stimulation: Its effects on alveolar type II cell function in the lung
    • Edwards YS: Stretch stimulation: its effects on alveolar type II cell function in the lung. Comp Biochem Physiol A Mol Integr Physiol 2001, 129:245-260. A concise review of the effects of mechanical strain on alveolar type II epithelial cells. The author focuses on the regulation of apoptosis, surtactant secretion, and cell proliferation and briefly highlights some implicated signal transduction pathways.
    • (2001) Comp Biochem Physiol A Mol Integr Physiol , vol.129 , pp. 245-260
    • Edwards, Y.S.1
  • 47
    • 0034916527 scopus 로고    scopus 로고
    • Mechanical stretch promotes alveolar epithelial type II cell differentiation
    • Sanchez-Esteban J, Cicchiello LA, Wang Y, et al.: Mechanical stretch promotes alveolar epithelial type II cell differentiation. J Appl Physiol 2001, 91:589-595.
    • (2001) J Appl Physiol , vol.91 , pp. 589-595
    • Sanchez-Esteban, J.1    Cicchiello, L.A.2    Wang, Y.3
  • 48
    • 0035490411 scopus 로고    scopus 로고
    • Mechanisms of surfactant exocytosis in alveolar type II cells in vitro and in vivo
    • Dietl P, Haller T, Mair N, et al.: Mechanisms of surfactant exocytosis in alveolar type II cells in vitro and in vivo. News Physiol Sci 2001, 16:239-243.
    • (2001) News Physiol Sci , vol.16 , pp. 239-243
    • Dietl, P.1    Haller, T.2    Mair, N.3
  • 49
    • 0034073046 scopus 로고    scopus 로고
    • Mechanical strain and dexamethasone selectively increase surfactant protein C and tropoelastin gene expression
    • Nakamura T, Liu M, Mourgeon E, et al.: Mechanical strain and dexamethasone selectively increase surfactant protein C and tropoelastin gene expression. Am J Physiol Lung Cell Mol Physiol 2000, 278:L974-L980.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Nakamura, T.1    Liu, M.2    Mourgeon, E.3
  • 50
    • 0035933151 scopus 로고    scopus 로고
    • Mechanical stress is communicated between different cell types to elicit matrix remodeling
    • Swartz MA, Tschumperlin DJ, Kamm RD, et al.: Mechanical stress is communicated between different cell types to elicit matrix remodeling. Proc Natl Acad Sci U S A 2001, 98:6180-6185.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6180-6185
    • Swartz, M.A.1    Tschumperlin, D.J.2    Kamm, R.D.3
  • 51
    • 0033856617 scopus 로고    scopus 로고
    • [Ca(2+](i) oscillations regulate type II cell exocytosis in the pulmonary alveolus
    • Ashino Y, Ying X, Dobbs LG, et al.: [Ca(2+](i) oscillations regulate type II cell exocytosis in the pulmonary alveolus. Am J Physiol Lung Cell Mol Physiol 2000, 279:L5-L13.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Ashino, Y.1    Ying, X.2    Dobbs, L.G.3
  • 52
    • 0036087399 scopus 로고    scopus 로고
    • Vascular regulation of type II cell exocytosis
    • Wang PM, Fujita E, Bhattacharya J: Vascular regulation of type II cell exocytosis. Am J Physiol Lung Cell Mol Physiol 2002, 282:L912-L916. Using an isolated perfused rat lung model, confocal microscopy, and fluorescent markers for calcium and lamellar bodies, the authors extend their previous work focusing on signaling between alveolar cells after alveolar deformation. In this study, they provide evidence that after hydrostatic capillary distension there is an increase in type II cell cytosolic calcium and, in turn, lamellar body exocytosis that was inhibited by calcium chelator and by gap junction function.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Wang, P.M.1    Fujita, E.2    Bhattacharya, J.3
  • 54
    • 0031709753 scopus 로고    scopus 로고
    • Paracrine mediators of mechanotransduction in lung development
    • Torday JS, Sanchez-Esterban J, Rubin LP: Paracrine mediators of mechanotransduction in lung development. Am J Med Sci 1998, 316:205-208.
    • (1998) Am J Med Sci , vol.316 , pp. 205-208
    • Torday, J.S.1    Sanchez-Esterban, J.2    Rubin, L.P.3
  • 55
    • 0036313943 scopus 로고    scopus 로고
    • Stretch-stimulated surfactant synthesis is coordinated by the paracrine actions of PTHrP and leptin
    • Torday JS, Rehan VK: Stretch-stimulated surfactant synthesis is coordinated by the paracrine actions of PTHrP and leptin. Am J Physiol Lung Cell Mol Physiol 2002, 283:L130-L135. The authors propose an epithelial-mesenchymal paracrine mechanism to explain the long-observed response of phosphatidylcholine excretion from stretched type II epithelial cells. Using primary fetal rat alveolar type II epithelial cells and lipofibroblasts, the authors provide evidence for paracrine PTHrP and leptin signaling between these two cells that is coordinated by mechanical stretch and ultimately increases surfactant secretion.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.283
    • Torday, J.S.1    Rehan, V.K.2
  • 57
    • 0032433191 scopus 로고    scopus 로고
    • Equibiaxial deformation-induced injury of alveolar epithelial cells in vitro
    • Tschumperlin DJ, Margulies SS: Equibiaxial deformation-induced injury of alveolar epithelial cells in vitro. Am J Physiol 1998, 275:L1173-L1183.
    • (1998) Am J Physiol , vol.275
    • Tschumperlin, D.J.1    Margulies, S.S.2
  • 58
    • 0026873553 scopus 로고
    • Stress failure of alveolar epithelial cells studied by scanning electron microscopy
    • Costello ML, Mathieu-Costello O, West JB: Stress failure of alveolar epithelial cells studied by scanning electron microscopy. Am Rev Respir Dis 1992, 145:1446-1455.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1446-1455
    • Costello, M.L.1    Mathieu-Costello, O.2    West, J.B.3
  • 59
    • 4244075844 scopus 로고    scopus 로고
    • Assessment of ventilator-induced plasma membrane wounding and repair in the intact lung
    • Gajic O, Lee J-H, Doerr CH, et al.: Assessment of ventilator-induced plasma membrane wounding and repair in the intact lung [abstract]. Am J Respir Crit Care Med 2002, 165:A783.
    • (2002) Am J Respir Crit Care Med , vol.165
    • Gajic, O.1    Lee, J.-H.2    Doerr, C.H.3
  • 60
    • 0033675586 scopus 로고    scopus 로고
    • Invited review: Plasma membrane stress failure in alveolar epithelial cells
    • Vlahakis NE, Hubmayr RD: Invited review: Plasma membrane stress failure in alveolar epithelial cells. J Appl Physiol 2000, 89:2490-2496.
    • (2000) J Appl Physiol , vol.89 , pp. 2490-2496
    • Vlahakis, N.E.1    Hubmayr, R.D.2
  • 61
    • 0030985763 scopus 로고    scopus 로고
    • Loss, restoration, and maintenance of plasma membrane integrity
    • McNeil PL, Steinhardt RA: Loss, restoration, and maintenance of plasma membrane integrity. J Cell Biol 1997, 137:1-4
    • (1997) J Cell Biol , vol.137 , pp. 1-4
    • McNeil, P.L.1    Steinhardt, R.A.2
  • 62
    • 0032876283 scopus 로고    scopus 로고
    • Characteristics of a membrane reservoir buffering membrane tension
    • Raucher D, Sheetz MP: Characteristics of a membrane reservoir buffering membrane tension. Biophys J 1999, 77:1992-2002.
    • (1999) Biophys J , vol.77 , pp. 1992-2002
    • Raucher, D.1    Sheetz, M.P.2
  • 63
    • 0035025267 scopus 로고    scopus 로고
    • Coping with the inevitable: How cells repair a torn surface membrane
    • McNeil PL, Terasaki M: Coping with the inevitable: how cells repair a torn surface membrane. Nat Cell Biol 2001, 3:E124-E129.
    • (2001) Nat Cell Biol , vol.3
    • McNeil, P.L.1    Terasaki, M.2
  • 64
    • 0035025806 scopus 로고    scopus 로고
    • Deformation-induced lipid trafficking in alveolar epithelial cells
    • Vlahakis NE, Schroeder MA, Pagano RE, et al.: Deformation-induced lipid trafficking in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 2001, 280:L938-L946. In an in vitro model using A549 cells, the authors demonstrate for the first time that after substratum deformation, which simulates mechanical ventilation, alveolar epithelial cells exocytose intracellular lipid to the plasma membrane in a vesicular, strain amplitude-dependent, and energy-dependent manner. This DILT serving to accommodate cell surface area increases as measured by confocal microscopy.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Vlahakis, N.E.1    Schroeder, M.A.2    Pagano, R.E.3
  • 65
    • 0036840592 scopus 로고    scopus 로고
    • Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure
    • Vlahakis NE, Schroeder MA, Pagano RE, et al.: Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. Am J Respir Crit Care Med 2002, 166:1282-1289. The authors extend their work to show that not only does DILT serve to accommodate deformation-induced increases in cell surface area but also to repair deformation-induced plasma membrane breaks in both A549 and in primary rat alveolar epithelial cells. Through manipulation of the physical properties of the lipid bilayer and cytoskeleton, they show that dynamic processes such as DILT are a greater determinant of plasma membrane breaks than the prestress state of the cell, as predicted by tensegrity. In addition, using a two-dye labeling technique, the authors were able to distinguish between wounded and resealed cells versus wounded and dead cells and highlight the experimental importance of making this distinction.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1282-1289
    • Vlahakis, N.E.1    Schroeder, M.A.2    Pagano, R.E.3
  • 66
    • 0033770910 scopus 로고    scopus 로고
    • Opposing views on tensegrity as a structural framework for understanding cell mechanics
    • Ingber DE: Opposing views on tensegrity as a structural framework for understanding cell mechanics. J Appl Physiol 2000, 89:1663-1670.
    • (2000) J Appl Physiol , vol.89 , pp. 1663-1670
    • Ingber, D.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.