High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 rep and cap

Gene Therapy

Volumn 6, Issue 6, 1999, Pages 986-993

  Conway, J E ^a   Ap Rhys, C M J ^a   Zolotukhin, I ^b   Zolotukhin, S ^b   Muzyczka, N ^b   Hayward, G S ^a   Byrne, B J ^b,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Adeno associated virus; Gene therapy; Herpes simplex virus; rAAV; Vector production

Indexed keywords

CAPSID PROTEIN; HELICASE; PLASMID DNA; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; HELPER VIRUS; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROVIRUS; VIRUS PURIFICATION; VIRUS RECOMBINANT; VIRUS TITRATION;

BLOTTING, WESTERN; CELL LINE; DEPENDOVIRUS; FLUORESCENT ANTIBODY TECHNIQUE; GENE THERAPY; GENETIC VECTORS; HUMANS; SIMPLEXVIRUS; TRANSFECTION; VIROLOGY; VIRUS REPLICATION;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS 2; ANIMALIA; HERPES; HUMAN HERPESVIRUS 1; MIRIDAE; SIMPLEXVIRUS;

EID: 0033054126     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300937     Document Type: Article

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