메뉴 건너뛰기




Volumn 316, Issue 10, 2010, Pages 1662-1680

Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin

Author keywords

Cellular senescence; Chaetocin; Chromatin condensation; Chromatin reorganization; Nuclear architecture; Thioredoxin

Indexed keywords

CHETOCIN; HISTONE; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 77953231674     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.03.008     Document Type: Article
Times cited : (20)

References (62)
  • 1
    • 0014725912 scopus 로고
    • Isolation and configuration of Chaetocin
    • Hauser D., Weber H.P., Sigg H.P. Isolation and configuration of Chaetocin. Helv. Chim. Acta 1970, 53:1061-1073.
    • (1970) Helv. Chim. Acta , vol.53 , pp. 1061-1073
    • Hauser, D.1    Weber, H.P.2    Sigg, H.P.3
  • 2
    • 30644474460 scopus 로고    scopus 로고
    • Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
    • Greiner D., Bonaldi T., Eskeland R., Roemer E., Imhof A. Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat. Chem. Biol. 2005, 1:143-145.
    • (2005) Nat. Chem. Biol. , vol.1 , pp. 143-145
    • Greiner, D.1    Bonaldi, T.2    Eskeland, R.3    Roemer, E.4    Imhof, A.5
  • 3
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007, 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 4
    • 33947214077 scopus 로고    scopus 로고
    • Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress
    • Isham C.R., Tibodeau J.D., Jin W., Xu R., Timm M.M., Bible K.C. Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress. Blood 2007, 109:2579-2588.
    • (2007) Blood , vol.109 , pp. 2579-2588
    • Isham, C.R.1    Tibodeau, J.D.2    Jin, W.3    Xu, R.4    Timm, M.M.5    Bible, K.C.6
  • 5
    • 64549104648 scopus 로고    scopus 로고
    • The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase
    • Tibodeau J., Benson L., Isham C., Owen W., Bible K. The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase. Antioxid. Redox Signal. 2009, 11:1097-1106.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 1097-1106
    • Tibodeau, J.1    Benson, L.2    Isham, C.3    Owen, W.4    Bible, K.5
  • 10
    • 52949133457 scopus 로고    scopus 로고
    • The meaning of gene positioning
    • Takizawa T., Meaburn K.J., Misteli T. The meaning of gene positioning. Cell 2008, 135:9-13.
    • (2008) Cell , vol.135 , pp. 9-13
    • Takizawa, T.1    Meaburn, K.J.2    Misteli, T.3
  • 11
    • 30044435641 scopus 로고    scopus 로고
    • Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones
    • Zinner R., Albiez H., Walter J., Peters A.H., Cremer T., Cremer M. Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones. Histochem. Cell Biol. 2006, 125:3-19.
    • (2006) Histochem. Cell Biol. , vol.125 , pp. 3-19
    • Zinner, R.1    Albiez, H.2    Walter, J.3    Peters, A.H.4    Cremer, T.5    Cremer, M.6
  • 13
    • 0037071535 scopus 로고    scopus 로고
    • Spatial organization of active and inactive genes and noncoding DNA within chromosome territories
    • Mahy N.L., Perry P.E., Gilchrist S., Baldock R.A., Bickmore W.A. Spatial organization of active and inactive genes and noncoding DNA within chromosome territories. J. Cell Biol. 2002, 157:579-589.
    • (2002) J. Cell Biol. , vol.157 , pp. 579-589
    • Mahy, N.L.1    Perry, P.E.2    Gilchrist, S.3    Baldock, R.A.4    Bickmore, W.A.5
  • 14
    • 0026724301 scopus 로고
    • Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2
    • Lengauer C., Riethman H.C., Speicher M.R., Taniwaki M., Konecki D., Green E.D., Becher R., Olson M.V., Cremer T. Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2. Cancer Res. 1992, 52:2590-2596.
    • (1992) Cancer Res. , vol.52 , pp. 2590-2596
    • Lengauer, C.1    Riethman, H.C.2    Speicher, M.R.3    Taniwaki, M.4    Konecki, D.5    Green, E.D.6    Becher, R.7    Olson, M.V.8    Cremer, T.9
  • 15
    • 11844291918 scopus 로고    scopus 로고
    • UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery
    • Mais C., Wright J.E., Prieto J.L., Raggett S.L., McStay B. UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery. Genes Dev. 2005, 19:50-64.
    • (2005) Genes Dev. , vol.19 , pp. 50-64
    • Mais, C.1    Wright, J.E.2    Prieto, J.L.3    Raggett, S.L.4    McStay, B.5
  • 17
    • 0035141289 scopus 로고    scopus 로고
    • Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells
    • Schermelleh L., Solovei I., Zink D., Cremer T. Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells. Chromosome Res. 2001, 9:77-80.
    • (2001) Chromosome Res. , vol.9 , pp. 77-80
    • Schermelleh, L.1    Solovei, I.2    Zink, D.3    Cremer, T.4
  • 19
    • 0036354627 scopus 로고    scopus 로고
    • Synergistic induction of the senescence-associated genes by 5-bromodeoxyuridine and AT-binding ligands in HeLa cells
    • Suzuki T., Michishita E., Ogino H., Fujii M., Ayusawa D. Synergistic induction of the senescence-associated genes by 5-bromodeoxyuridine and AT-binding ligands in HeLa cells. Exp. Cell Res. 2002, 276:174-184.
    • (2002) Exp. Cell Res. , vol.276 , pp. 174-184
    • Suzuki, T.1    Michishita, E.2    Ogino, H.3    Fujii, M.4    Ayusawa, D.5
  • 21
    • 0036665581 scopus 로고    scopus 로고
    • Quantitative profiling of proteins in complex mixtures using liquid chromatography and mass spectrometry
    • Chelius D., Bondarenko P.V. Quantitative profiling of proteins in complex mixtures using liquid chromatography and mass spectrometry. J. Proteome Res. 2002, 1:317-323.
    • (2002) J. Proteome Res. , vol.1 , pp. 317-323
    • Chelius, D.1    Bondarenko, P.V.2
  • 23
    • 67651158792 scopus 로고    scopus 로고
    • Chromosome shattering: a mitotic catastrophe due to chromosome condensation failure
    • B. Hübner, H. Strickfaden, S. Müller, M. Cremer, T. Cremer, Chromosome shattering: a mitotic catastrophe due to chromosome condensation failure, Eur. Biophys. J. 38 (2009) 729-747.
    • (2009) Eur. Biophys. J. , vol.38 , pp. 729-747
    • Hübner, B.1    Strickfaden, H.2    Müller, S.3    Cremer, M.4    Cremer, T.5
  • 25
    • 0028852858 scopus 로고
    • Activation of osmium ammine by SO2-generating chemicals for EM Feulgen-type staining of DNA
    • Vazquez-Nin G.H., Biggiogera M., Echeverria O.M. Activation of osmium ammine by SO2-generating chemicals for EM Feulgen-type staining of DNA. Eur. J. Histochem. 1995, 39:101-106.
    • (1995) Eur. J. Histochem. , vol.39 , pp. 101-106
    • Vazquez-Nin, G.H.1    Biggiogera, M.2    Echeverria, O.M.3
  • 26
    • 0031440380 scopus 로고    scopus 로고
    • Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods
    • Lecoeur H., Ledru E., Prevost M.C., Gougeon M.L. Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods. J. Immunol. Methods 1997, 209:111-123.
    • (1997) J. Immunol. Methods , vol.209 , pp. 111-123
    • Lecoeur, H.1    Ledru, E.2    Prevost, M.C.3    Gougeon, M.L.4
  • 27
    • 0034660087 scopus 로고    scopus 로고
    • The Ki-67 protein: fascinating forms and an unknown function
    • Endl E., Gerdes J. The Ki-67 protein: fascinating forms and an unknown function. Exp. Cell Res. 2000, 257:231-237.
    • (2000) Exp. Cell Res. , vol.257 , pp. 231-237
    • Endl, E.1    Gerdes, J.2
  • 28
    • 0141613756 scopus 로고    scopus 로고
    • Phosphorylation of serine 10 in histone H3, what for?
    • Prigent C., Dimitrov S. Phosphorylation of serine 10 in histone H3, what for?. J. Cell Sci. 2003, 116:3677-3685.
    • (2003) J. Cell Sci. , vol.116 , pp. 3677-3685
    • Prigent, C.1    Dimitrov, S.2
  • 29
    • 34248155774 scopus 로고    scopus 로고
    • Evolutionarily conserved, cell type and species-specific higher order chromatin arrangements in interphase nuclei of primates
    • Neusser M., Schubel V., Koch A., Cremer T., Muller S. Evolutionarily conserved, cell type and species-specific higher order chromatin arrangements in interphase nuclei of primates. Chromosoma 2007, 116:307-320.
    • (2007) Chromosoma , vol.116 , pp. 307-320
    • Neusser, M.1    Schubel, V.2    Koch, A.3    Cremer, T.4    Muller, S.5
  • 30
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E.S. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 31
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • Grewal S.I., Moazed D. Heterochromatin and epigenetic control of gene expression. Science 2003, 301:798-802.
    • (2003) Science , vol.301 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 32
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther M.G., Levine S.S., Boyer L.A., Jaenisch R., Young R.A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130:77-88.
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 33
    • 33746457753 scopus 로고    scopus 로고
    • Enhanced histone acetylation and transcription: a dynamic perspective
    • Clayton A.L., Hazzalin C.A., Mahadevan L.C. Enhanced histone acetylation and transcription: a dynamic perspective. Mol. Cell 2006, 23:289-296.
    • (2006) Mol. Cell , vol.23 , pp. 289-296
    • Clayton, A.L.1    Hazzalin, C.A.2    Mahadevan, L.C.3
  • 36
    • 33947236204 scopus 로고    scopus 로고
    • Molecular dissection of formation of senescence-associated heterochromatin foci
    • Zhang R., Chen W., Adams P.D. Molecular dissection of formation of senescence-associated heterochromatin foci. Mol. Cell. Biol. 2007, 27:2343-2358.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2343-2358
    • Zhang, R.1    Chen, W.2    Adams, P.D.3
  • 38
    • 0037166937 scopus 로고    scopus 로고
    • Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome
    • Chadwick B.P., Willard H.F. Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome. J. Cell Biol. 2002, 157:1113-1123.
    • (2002) J. Cell Biol. , vol.157 , pp. 1113-1123
    • Chadwick, B.P.1    Willard, H.F.2
  • 39
    • 67349120863 scopus 로고    scopus 로고
    • Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions
    • Arner E.S. Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions. Biochim. Biophys. Acta 2009, 1790:495-526.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 495-526
    • Arner, E.S.1
  • 40
    • 0031985249 scopus 로고    scopus 로고
    • Effect of l-buthionine-(S, R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure
    • Cuzzocrea S., Zingarelli B., O'Connor M., Salzman A.L., Szabo C. Effect of l-buthionine-(S, R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure. Br. J. Pharmacol. 1998, 123:525-537.
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 525-537
    • Cuzzocrea, S.1    Zingarelli, B.2    O'Connor, M.3    Salzman, A.L.4    Szabo, C.5
  • 41
    • 34547644483 scopus 로고    scopus 로고
    • Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
    • Lu J., Chew E.H., Holmgren A. Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:12288-12293.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 12288-12293
    • Lu, J.1    Chew, E.H.2    Holmgren, A.3
  • 42
    • 10044296098 scopus 로고    scopus 로고
    • Multidrug-resistant hela cells overexpressing MRP1 exhibit sensitivity to cell killing by hyperthermia: interactions with etoposide
    • Souslova T., Averill-Bates D.A. Multidrug-resistant hela cells overexpressing MRP1 exhibit sensitivity to cell killing by hyperthermia: interactions with etoposide. Int. J. Radiat. Oncol. Biol. Phys. 2004, 60:1538-1551.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.60 , pp. 1538-1551
    • Souslova, T.1    Averill-Bates, D.A.2
  • 44
    • 14644410453 scopus 로고    scopus 로고
    • The signals and pathways activating cellular senescence
    • Ben-Porath I., Weinberg R.A. The signals and pathways activating cellular senescence. Int. J. Biochem. Cell Biol. 2005, 37:961-976.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 961-976
    • Ben-Porath, I.1    Weinberg, R.A.2
  • 45
    • 34648816970 scopus 로고    scopus 로고
    • Cellular senescence and chromatin structure
    • Funayama R., Ishikawa F. Cellular senescence and chromatin structure. Chromosoma 2007, 116:431-440.
    • (2007) Chromosoma , vol.116 , pp. 431-440
    • Funayama, R.1    Ishikawa, F.2
  • 46
    • 33846135791 scopus 로고    scopus 로고
    • Oncogenes and senescence: breaking down in the fast lane
    • Hemann M.T., Narita M. Oncogenes and senescence: breaking down in the fast lane. Genes Dev. 2007, 21:1-5.
    • (2007) Genes Dev. , vol.21 , pp. 1-5
    • Hemann, M.T.1    Narita, M.2
  • 47
    • 12144283456 scopus 로고    scopus 로고
    • The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway
    • Chan H.M., Narita M., Lowe S.W., Livingston D.M. The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway. Genes Dev. 2005, 19:196-201.
    • (2005) Genes Dev. , vol.19 , pp. 196-201
    • Chan, H.M.1    Narita, M.2    Lowe, S.W.3    Livingston, D.M.4
  • 48
  • 50
    • 33746752125 scopus 로고    scopus 로고
    • A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
    • Narita M., Narita M., Krizhanovsky V., Nunez S., Chicas A., Hearn S.A., Myers M.P., Lowe S.W. A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell 2006, 126:503-514.
    • (2006) Cell , vol.126 , pp. 503-514
    • Narita, M.1    Narita, M.2    Krizhanovsky, V.3    Nunez, S.4    Chicas, A.5    Hearn, S.A.6    Myers, M.P.7    Lowe, S.W.8
  • 51
    • 49149099329 scopus 로고    scopus 로고
    • BMI-1026 treatment can induce SAHF formation by activation of Erk1/2
    • Seo H.J., Park H.J., Choi H.S., Hwang S.Y., Park J.S., Seong Y.S. BMI-1026 treatment can induce SAHF formation by activation of Erk1/2. BMB Rep. 2008, 41:523-528.
    • (2008) BMB Rep. , vol.41 , pp. 523-528
    • Seo, H.J.1    Park, H.J.2    Choi, H.S.3    Hwang, S.Y.4    Park, J.S.5    Seong, Y.S.6
  • 52
    • 11144284688 scopus 로고    scopus 로고
    • Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts
    • Ukekawa R., Maegawa N., Mizutani E., Fujii M., Ayusawa D. Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts. Biosci. Biotechnol. Biochem. 2004, 68:2395-2397.
    • (2004) Biosci. Biotechnol. Biochem. , vol.68 , pp. 2395-2397
    • Ukekawa, R.1    Maegawa, N.2    Mizutani, E.3    Fujii, M.4    Ayusawa, D.5
  • 54
    • 26244436644 scopus 로고    scopus 로고
    • SA beta Gal staining: biomarker or delusion
    • Cristofalo V.J. SA beta Gal staining: biomarker or delusion. Exp. Gerontol. 2005, 40:836-838.
    • (2005) Exp. Gerontol. , vol.40 , pp. 836-838
    • Cristofalo, V.J.1
  • 56
    • 33847703331 scopus 로고    scopus 로고
    • Cellular senescence and chromatin organisation
    • Narita M. Cellular senescence and chromatin organisation. Br. J. Cancer 2007, 96:686-691.
    • (2007) Br. J. Cancer , vol.96 , pp. 686-691
    • Narita, M.1
  • 59
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • Cremer T., Cremer C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat. Rev. Genet. 2001, 2:292-301.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 292-301
    • Cremer, T.1    Cremer, C.2
  • 60
    • 35649020707 scopus 로고    scopus 로고
    • The perichromatin region: a functional compartment in the nucleus that determines large-scale chromatin folding
    • Fakan S., van Driel R. The perichromatin region: a functional compartment in the nucleus that determines large-scale chromatin folding. Semin. Cell Dev. Biol. 2007, 18:676-681.
    • (2007) Semin. Cell Dev. Biol. , vol.18 , pp. 676-681
    • Fakan, S.1    van Driel, R.2
  • 61
    • 33646729244 scopus 로고    scopus 로고
    • Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations
    • Branco M.R., Pombo A. Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLoS Biol. 2006, 4:e138.
    • (2006) PLoS Biol. , vol.4
    • Branco, M.R.1    Pombo, A.2
  • 62
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner E.S., Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur. J. Biochem. 2000, 267:6102-6109.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.