Constitutive activation of signal transducer and activator of transcription 3 regulates expression of vascular endothelial growth factor in human meningioma differentiation

Journal of Cancer Research and Clinical Oncology

Volumn 136, Issue 7, 2010, Pages 981-988

  Zhang, Mao Xiu ^a,b   Zhao, Xu ^c   Wang, Zhi Gang ^c   Zhao, Wei Ming ^a   Wang, Yun Shan ^a,b  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG UNIVERSITY   (China)

^c THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

Author keywords

Constitutive activation; Human meningioma; P STAT3; STAT3; VEGF

Indexed keywords

JANUS KINASE 1; MESSENGER RNA; ONCOPROTEIN; PHOSPHORYLATED JANUS TYROSINE KINASE 1; PHOSPHORYLATED SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER GRADING; CANCER GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MENINGIOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TUMOR DIFFERENTIATION; UPREGULATION; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; BLOTTING, WESTERN; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; JANUS KINASE 1; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; NEOPLASM STAGING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 77953231104     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-009-0743-9     Document Type: Article

References (36)

1. S Akira 1999 Functional roles of STAT family proteins: lessons from knockout mice Stem Cells 17 138 146 10.1002/stem.170138 1:CAS:528: DyaK1MXjsF2gtLk%3D 10342556
2. RA Berkman MJ Merrill WC Reinhold WT Monacci A Saxena WC Clark JT Robertson IU Ali EH Oldfield 1993 Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms J Clin Invest 91 153 159 10.1172/JCI116165 1:CAS:528: DyaK3sXpvFamuw%3D%3D 8380810
3. AC Bharti N Donato BB Aggarwal 2003 Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells J Immunol 171 3863 3871 1:CAS:528:DC%2BD3sXnvFSru7g%3D 14500688
4. T Bowman R Garcia J Turkson R Jove 2000 STATs in oncogenesis Oncogene 19 2474 2488 10.1038/sj.onc.1203527 1:CAS:528:DC%2BD3cXktVGhsb8%3D 10851046
5. N Carlesso DA Frank JD Griffin 1996 Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl J Exp Med 183 811 820 10.1084/jem.183.3.811 1:CAS:528:DyaK28XhvV2ru74%3D 8642285 (Pubitemid 26113953)
6. R Catlett-Falcone TH Landowski MM Oshiro J Turkson A Levitzki R Savino G Ciliberto L Moscinski JL Fernández-Luna G Nuñez WS Dalton R Jove 1999 Constitutive activation of STAT3 signaling confers resistance to apoptosis in human U266 myeloma cells Immunity 10 105 115 10.1016/S1074-7613(00)80011-4 1:CAS:528:DyaK1MXhtFarsbo%3D 10023775 (Pubitemid 29077388)
7. E Cattaneo L Magrassi C De-Fraja L Conti I Di Gennaro G Butti S Govoni 1998 Variations in the levels of the JAK/STAT and ShcA proteins in human brain tumors Anticancer Res 18 2381 2387 1:CAS:528:DyaK1cXlsF2jurY%3D 9703883
8. SH Chen DA Murphy W Lassoued G Thurston MD Feldman WM Lee 2008 Activated STAT3 is a mediator and biomarker of VEGF endothelial activation Cancer Biol Ther 7 1994 2003 1:CAS:528:DC%2BD1MXit1GltLc%3D 18981713
9. P Coppo S Flamant V De Mas P Jarrier M Guillier ML Bonnet C Lacout F Guilhot W Vainchenker AG Turhan 2006 BCR-ABL activates STAT3 via JAK and MEK pathways in human cells Br J Haematol 134 171 179 10.1111/j.1365-2141.2006. 06161.x 1:CAS:528:DC%2BD28Xot1ahtL4%3D 16846476 (Pubitemid 43893908)
10. C De-Fraja L Conti S Govoni F Battaini E Cattaneo 2000 STAT signalling in the mature and aging brain Int J Dev Neurosci 18 439 446 10.1016/S0736-5748(00) 00007-1 1:CAS:528:DC%2BD3cXks1Sqs70%3D 10817928 (Pubitemid 30243074)
11. N Ferrara HP Gerber J LeCouter 2003 The biology of VEGF and its receptors Nat Med 9 669 676 10.1038/nm0603-669 1:CAS:528:DC%2BD3sXktFOnur4%3D 12778165 (Pubitemid 36749215)
12. J Folkman 2001 Angiogenesis-dependent diseases Semin Oncol 28 536 542 10.1016/S0093-7754(01)90021-1 1:STN:280:DC%2BD3MnptlOguw%3D%3D 11740806
13. L Gautron V De Smedt-Peyrusse S Layé 2006 Characterization of STAT3-expressing cells in the postnatal rat brain Brain Res 1098 26 32 10.1016/j.brainres.2006.04.115 1:CAS:528:DC%2BD28XovVShsbs%3D 16764840 (Pubitemid 44277992)
14. D Guschin N Rogers J Briscoe B Witthuhn D Watling F Horn S Pellegrini K Yasukawa P Heinrich GR Stark 1995 A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6 EMBO J 14 1421 1429 1:CAS:528:DyaK2MXlsFShsrg%3D 7537214
15. V Haridas G Nishimura ZX Xu F Connolly M Hanausek Z Walaszek R Zoltaszek JU Gutterman 2009 Avicin D: a protein reactive plant isoprenoid dephosphorylates STAT3 by regulating both kinase and phosphatase activities PLoS One 4 e5578 10.1371/journal.pone.0005578 19440292
16. H Huang J Held-Feindt R Buhl HM Mehdorn R Mentlein 2005 Expression of VEGF and its receptors in different brain tumors Neurol Res 27 371 377 10.1179/016164105X39833 1:CAS:528:DC%2BD2MXlslemsL8%3D 15949234
17. ES Kim SY Hong HK Lee SW Kim MJ An TI Kim KR Lee WH Kim JH Cheon 2008 Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells Oncol Rep 20 1321 1327 1:CAS:528:DC%2BD1MXjs1Giug%3D%3D 19020709
18. L Knoops T Hornakova Y Royer SN Constantinescu JC Renauld 2008 JAK kinases overexpression promotes in vitro cell transformation Oncogene 27 1511 1519 10.1038/sj.onc.1210800 1:CAS:528:DC%2BD1cXivFyrsLg%3D 17873904 (Pubitemid 351347883)
19. CK Lee HA Bluyssen DE Levy 1997 Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity J Biol Chem 272 21872 21877 10.1074/jbc.272.35.21872 1:CAS:528:DyaK2sXlslOms70%3D 9268319 (Pubitemid 27382804)
20. S Loeffler B Fayard J Weis J Weissenberger 2005 Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1 Int J Cancer 115 202 213 10.1002/ijc.20871 1:CAS:528:DC%2BD2MXjvFWjs78%3D 15688401 (Pubitemid 40586728)
21. L Magrassi C De-Fraja L Conti G Butti L Infuso S Govoni E Cattaneo 1999 Expression of the JAK and STAT superfamilies in human meningiomas J Neurosurg 91 440 446 10.3171/jns.1999.91.3.0440 1:CAS:528:DyaK1MXmtV2rt70%3D 10470819
22. K Mahboubi F Li J Plescia NC Kirkiles-Smith M Mesri Y Du JM Carroll JA Elias DC Altieri JS Pober 2001 Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway Lab Invest 81 327 334 1:CAS:528:DC%2BD3MXivVKqsLw%3D 11310826
23. G Niu KL Wright M Huang L Song E Haura J Turkson S Zhang T Wang D Sinibaldi D Coppola R Heller LM Ellis J Karras J Bromberg D Pardoll R Jove H Yu 2002 Constitutive STAT3 activity up-regulates VEGF expression and tumor angiogenesis Oncogene 21 2000 2008 10.1038/sj.onc.1205260 1:CAS:528: DC%2BD38XivVelur4%3D 11960372
24. Y Ohta Y Endo M Tanaka J Shimizu M Oda Y Hayashi Y Watanabe T Sasaki 1996 Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer Clin Cancer Res 2 1411 1416 1:CAS:528:DyaK28XltlGqs7Y%3D 9816315 (Pubitemid 26299442)
25. M Preusser P Birner IM Ambros PF Ambros H Budka AL Harris JA Hainfellner 2005 DEC1 expression in 1p-aberrant oligodendroglial neoplasms Histol Histopathol 20 1173 1176 1:CAS:528:DC%2BD2MXht1OksLjM 16136500
26. SJ Rodig MA Meraz JM White PA Lampe JK Riley CD Arthur KL King KC Sheehan L Yin D Pennica EM Johnson Jr RD Schreiber 1998 Disruption of the JAK1 gene demonstrates obligatory and nonredundant roles of the JAKs in cytokine-induced biologic responses Cell 93 373 383 10.1016/S0092-8674(00)81166-6 1:CAS:528:DyaK1cXjtFCjtLs%3D 9590172 (Pubitemid 28232082)
27. J Rubin Grandis Q Zeng SD Drenning 2000 Epidermal growth factor receptor-mediated STAT3 signaling blocks apoptosis in head and neck cancer Laryngoscope 110 868 874 10.1097/00005537-200005000-00016 1:STN:280: DC%2BD3c3msFKntw%3D%3D 10807365
28. LK Schaefer Z Ren GN Fuller TS Schaefer 2002 Constitutive activation of STAT3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2) Oncogene 21 2058 2065 10.1038/sj.onc.1205263 1:CAS:528:DC%2BD38XivVelurg%3D 11960378
29. K Takeda K Noguchi W Shi T Tanaka M Matsumoto N Yoshida T Kishimoto S Akira 1997 Targeted disruption of the mouse STAT3 gene leads to early embryonic lethality Proc Natl Acad Sci USA 94 3801 3804 10.1073/pnas.94.8.3801 1:CAS:528:DyaK2sXis1artLc%3D 9108058 (Pubitemid 27180453)
30. L Tam LM McGlynn P Traynor R Mukherjee JM Bartlett J Edwards 2007 Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer Br J Cancer 97 378 383 10.1038/sj.bjc.6603871 1:CAS:528:DC%2BD2sXotlSgtr8%3D 17595657 (Pubitemid 47196744)
31. SS Tian P Lamb HM Seidel RB Stein J Rosen 1994 Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor Blood 84 1760 1764 1:CAS:528:DyaK2cXmt1ynsro%3D 7521688
32. J Turkson R Jove 2000 STAT proteins: novel molecular targets for cancer drug discovery Oncogene 27 6613 6626 10.1038/sj.onc.1204086 (Pubitemid 32197700)
33. H Wang H Wang W Zhang HJ Huang WS Liao GN Fuller 2004 Analysis of the activation status of Akt, NFkappaB, and STAT3 in human diffuse gliomas Lab Invest 84 941 951 10.1038/labinvest.3700123 1:CAS:528:DC%2BD2cXmvF2ksL0%3D 15184909 (Pubitemid 39025029)
34. RM Weber-Nordt C Egen J Wehinger W Ludwig V Gouilleux-Gruart R Mertelsmann J Finke 1996 Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines Blood 88 809 816 1:CAS:528:DyaK28Xks1Cjt7w%3D 8704235
35. D Wei X Le L Zheng L Wang JA Frey AC Gao Z Peng S Huang HQ Xiong JL Abbruzzese K Xie 2003 STAT3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis Oncogene 22 319 329 10.1038/sj.onc.1206122 1:CAS:528: DC%2BD3sXlsV2ltA%3D%3D 12545153 (Pubitemid 36194328)
36. Y Zhang J Turkson C Carter-Su T Smithgall A Levitzki A Kraker JJ Krolewski P Medveczky R Jove 2000 Activation of STAT3 in v-Src-transformed fibroblasts requires cooperation of JAK1 kinase activity J Biol Chem 275 24935 24944 10.1074/jbc.M002383200 1:CAS:528:DC%2BD3cXlsl2jtLk%3D 10823829 (Pubitemid 30626601)