COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

Journal of Clinical Investigation

Volumn 120, Issue 6, 2010, Pages 2119-2130

  Van De Sluis, Bart ^a,b   Mao, Xicheng ^c,d   Zhai, Yali ^c   Groot, Arjan J ^a   Vermeulen, Jeroen F ^a   Van Der Wall, Elsken ^a   Van Diest, Paul J ^a   Hofker, Marten H ^b   Wijmenga, Cisca ^b   Klomp, Leo W ^a   Cho, Kathleen R ^c   Fearon, Eric R ^c   Vooijs, Marc ^a,e   Burstein, Ezra ^c,d,f  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; INHIBITOR PROTEIN; PROTEIN COMM DOMAIN CONTAINING 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CANCER SURVIVAL; CHICK; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; DNA TRANSCRIPTION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG METASTASIS; MELANOMA CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL LINE; TUMOR XENOGRAFT;

ANIMALS; CARRIER PROTEINS; CELL LINE; DIMERIZATION; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASMS; NF-KAPPA B; PROTEIN MULTIMERIZATION; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS;

EID: 77953207180     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI40583     Document Type: Article

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