Formulation and in vitro-in vivo evaluation of black raspberry extract-loaded PLGA/PLA injectable millicylindrical implants for sustained delivery of chemopreventive anthocyanins

Pharmaceutical Research

Volumn 27, Issue 4, 2010, Pages 628-643

  Desai, Kashappa Goud H ^a   Olsen, Karl F ^a   Mallery, Susan R ^b   Stoner, Gary D ^c   Schwendeman, S P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Black raspberry anthocyanins; Cancer; Chemoprevention; Controlled release; Inclusion complex; Injectable millicylindrical implants; Microencapsulation; Oral; PLA; PLGA; Triacetyl cyclodextrin

Indexed keywords

ALCOHOL; ANTHOCYANIN; BETA CYCLODEXTRIN; CYANIDIN 3 GLUCOSIDE; CYANIDIN 3 RUTINOSIDE; CYANIDIN 3 SAMBUBIOSIDE; PHOSPHATE BUFFERED SALINE; PLANT EXTRACT; POLYGLACTIN; POLYLACTIC ACID; POLYSORBATE 80; RASPBERRY EXTRACT; UNCLASSIFIED DRUG; WATER; ANTINEOPLASTIC AGENT; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG FORMULATION; DRUG IDENTIFICATION; DRUG RELEASE; DRUG SCREENING; DRUG STABILITY; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; POROSITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RASPBERRY; RAT; SUSTAINED RELEASE FORMULATION; TEMPERATURE; ULTRAVIOLET SPECTROSCOPY; WATER TRANSPORT; X RAY DIFFRACTION; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; FRUIT; INJECTION; PROSTHESES AND ORTHOSES; ROSACEAE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTHOCYANINS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DELAYED-ACTION PREPARATIONS; FRUIT; INJECTIONS; LACTIC ACID; MALE; POLYGLYCOLIC ACID; POLYMERS; PROSTHESES AND IMPLANTS; RATS; RATS, SPRAGUE-DAWLEY; ROSACEAE;

EID: 77953163647     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-0038-5     Document Type: Article

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