Controlled release of a water-soluble drug, captopril, by a combination of hydrophilic and hydrophobic cyclodextrin derivatives

Journal of Controlled Release

Volumn 66, Issue 2-3, 2000, Pages 271-280

  Ikeda, Yoichi ^a   Kimura, Kenya ^b   Hirayama, Fumitoshi ^b   Arima, Hidetoshi ^b   Uekama, Kaneto ^b  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

2 Hydroxypropyl cyclodextrin; Captopril; Combination of hydrophilic and hydrophobic cyclodextrins; Controlled release; Gel formation; Perbutanoyl cyclodextrin

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BETA CYCLODEXTRIN; CAPTOPRIL; CAPTOPRIL R; CYCLODEXTRIN DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GELATIN; PERBUTANOYL BETA CYCLODEXTRIN; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DOG; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG SOLUBILITY; GEL; HYDROPHILICITY; HYDROPHOBICITY; MALE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED RELEASE PREPARATION;

ABSORPTION; ANIMALS; BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CAPTOPRIL; CYCLODEXTRINS; DELAYED-ACTION PREPARATIONS; DOGS; DRUG DELIVERY SYSTEMS; MALE; TEMPERATURE; X-RAY DIFFRACTION;

EID: 0034657894     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00286-2     Document Type: Article

References (21)

1. Saenger W. Cyclodextrin inclusion compounds in research and industry. Angew. Chem. Int. Ed. Engl. 19:1980;344-362.
2. Duchêne D., Vaution C., Glomot F. Cyclodextrins: their value in pharmaceutical technology. Drug Dev. Ind. Pharm. 12:1986;2193-2215.
3. Uekama K., Otagiri M. Cyclodextrins in drug carrier system. CRC Crit. Rev. Ther. Drug Carrier Systems. 3:1987;1-40.
4. Uekama K., Hirayama F., Irie T. Cyclodextrin drug carrier systems. Chem. Rev. 98:1998;2045-2076.
5. 7m-β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) complexation. Int. J. Pharm. 165:1998;69-78.
6. Horiuchi Y., Hirayama F., Uekama K. Slow-release characteristics of diltiazem from ethylated β-cyclodextrin complexes. J. Pharm. Sci. 79:1990;128-132.
7. Másson M., Loftsson T., Másson G., Stefánsson E. Cyclodextrins as permeation enhancers: some theoretical evaluations and in vitro testing. J. Control. Release. 59:1999;107-118.
8. Fridriksdóttir H., Loftsson T., Stefánsson E. Formulation and testing of methazolamide cyclodextrin eye drop solutions. J. Control. Release. 44:1997;95-99.
9. Soliman O.A., Kimura K., Hirayama F., et al. Controlled release of diltiazem by a combination of short- and long-chain peracylated β-cyclodextrin in dogs. Pharm. Sci. 2:1996;533-536.
10. Wang Z., Hirayama F., Ikegami K., Uekama K. Release characteristics of nifedipine from 2-hydroxypropyl-β-cyclodextrin complex during storage and its modification of hybridizing polyvinylpyrrolidone K-30. Chem. Pharm. Bull. 41:1993;1822-1826.
11. Wang Z., Horikawa T., Hirayama F., Uekama K. Design and in-vitro evaluation of a modified-release oral dosage form of nifedipine by hybridization of hydroxypropyl-β-cyclodextrin and hydroxypropylcellulose. J. Pharm. Pharmacol. 45:1993;942-946.
12. Hirayama F., Yamanaka M., Horikawa T., Uekama K. Characterization of peracylated β-cyclodextrins with different chain lengths as a novel sustained release carrier for water-soluble drugs. Chem. Pharm. Bull. 43:1995;130-136.
13. Hayashi K., Miyamoto M., Sekine Y. Determination of captopril and its mixed disulfides in plasma and urine by high-performance liquid chromatography. J. Chromatogr. 338:1985;161-169.
14. Kanaoka Y., Takahashi T., Machida M., Yamamoto K., Sekine T. N-(3-Fluoranthyl)maleimide (FAM): A medium lifetime fluorescent thiol reagent. Chem. Pharm. Bull. 24:1976;1417-1419.
15. Giordano F., Bruni G., Bettinetti G.P. Solid-state microcalorimetry on drug-cyclodextrin binary systems. J. Thermal Anal. 38:1992;2683-2691.
16. Korsmeyer R.W., Gurny R., Doelker E., Buri P., Peppas N.A. Mechanisms of solute release from porous hydrophilic polymers. Int. J. Pharm. 15:1983;25-35.
17. Seta Y., Higuchi F., Otsuka T., et al. Preparation and pharmacological evaluation of captopril sustained-release dosage forms using oily semisolid matrix. Int. J. Pharm. 41:1988;255-262.
18. Ogata H., Aoyagi N., Kaniwa N., et al. Evaluation of beagle dogs as an animal model for bioavailability testing of cinnarizine capsules. Int. J. Pharm. 29:1986;121-126.
19. Mizuta H., Kawazoe Y., Haga K., Ogawa K. Effect of meals on gastric emptying and small intestinal transit times of a suspension in the beagle dog assessed using acetaminophen and salicylazosulfapyridine as markers. Chem. Pharm. Bull. 38:1990;2224-2227.
20. Yuasa H., Ozeki T., Kanaya Y., Oishi K., Oyake T. Application of the solid dispersion method to controlled release of medicine. I. Controlled release of water soluble medicine by using solid dispersion. Chem. Pharm. Bull. 39:1991;465-467.
21. Ozeki T., Yuasa H., Kanaya Y., Oishi K. Application of the solid dispersion method to the controlled release of medicine. V. Suppression mechanism of the medicine release rate in the three-component solid dispersion system. Chem. Pharm. Bull. 42:1994;337-343.