-
1
-
-
0028920576
-
Guidelines for clinical trials in systemic sclerosis (scleroderma). I. disease modifying interventions. The American College of Rheumatology Committee on Design and Outcomes in Clinical Trials in Systemic sclerosis
-
White B, Bauer E A, Goldsmith L A. Guidelines for clinical trials in systemic sclerosis (scleroderma). I. disease modifying interventions. The American College of Rheumatology Committee on Design and Outcomes in Clinical Trials in Systemic sclerosis. Arthritis Rheum 1995, 38:351-360.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 351-360
-
-
White, B.1
Bauer, E.A.2
Goldsmith, L.A.3
-
3
-
-
34248379222
-
Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
-
Walker U A, Tyndall A, Czirják L. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann Rheum Dis 2007, 66:754-763.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 754-763
-
-
Walker, U.A.1
Tyndall, A.2
Czirják, L.3
-
4
-
-
47849097487
-
The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement
-
Hunzelmann N, Genth E, Krieg T. The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement. Rheumatology (Oxford) 2008, 47:1185-1192.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 1185-1192
-
-
Hunzelmann, N.1
Genth, E.2
Krieg, T.3
-
6
-
-
66149112569
-
European League Against Rheumatism (EULAR) Scleroderma Trial and Research group (EUSTAR) recommendations for the treatment of systemic sclerosis: methods of elaboration and results of systematic literature research
-
Avouac J, Kowal-Bielecka O, Landewe R. European League Against Rheumatism (EULAR) Scleroderma Trial and Research group (EUSTAR) recommendations for the treatment of systemic sclerosis: methods of elaboration and results of systematic literature research. Ann Rheum Dis 2009, 68:629-634.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 629-634
-
-
Avouac, J.1
Kowal-Bielecka, O.2
Landewe, R.3
-
7
-
-
66149100618
-
EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR)
-
Kowal-Bielecka O, Landewé R, Avouac J. EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR). Ann Rheum Dis 2009, 68:620-628.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 620-628
-
-
Kowal-Bielecka, O.1
Landewé, R.2
Avouac, J.3
-
8
-
-
33751104764
-
Esophageal involvement in scleroderma: gastroesophageal reflux, the common problem
-
Ntoumazios S K, Voulgari P V, Potsis K, Koutis E, Tsifetaki N, Assimakopoulos D A. Esophageal involvement in scleroderma: gastroesophageal reflux, the common problem. Semin Arthritis Rheum 2006, 36:173-181.
-
(2006)
Semin Arthritis Rheum
, vol.36
, pp. 173-181
-
-
Ntoumazios, S.K.1
Voulgari, P.V.2
Potsis, K.3
Koutis, E.4
Tsifetaki, N.5
Assimakopoulos, D.A.6
-
9
-
-
62849100599
-
High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy
-
Hunzelmann N, Moinzadeh P, Genth E. High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy. Arthritis Res Ther 2009, 11:R30.
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Hunzelmann, N.1
Moinzadeh, P.2
Genth, E.3
-
10
-
-
33745227399
-
Cyclophosphamide versus placebo in scleroderma lung disease
-
Tashkin D P, Elashoff R, Clements P J. Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 2006, 354:2655-2666.
-
(2006)
N Engl J Med
, vol.354
, pp. 2655-2666
-
-
Tashkin, D.P.1
Elashoff, R.2
Clements, P.J.3
-
11
-
-
34347266509
-
Changes in causes of death in systemic sclerosis, 1972-2002
-
Steen V D, Medsger T A. Changes in causes of death in systemic sclerosis, 1972-2002. Ann Rheum Dis 2007, 66:940-944.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 940-944
-
-
Steen, V.D.1
Medsger, T.A.2
-
12
-
-
0036124419
-
Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients
-
Ferri C, Valentini G, Cozzi F. Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients. Medicine (Baltimore) 2002, 81:139-153.
-
(2002)
Medicine (Baltimore)
, vol.81
, pp. 139-153
-
-
Ferri, C.1
Valentini, G.2
Cozzi, F.3
-
13
-
-
74449085877
-
Determinants of Morbidity and Mortality of Systemic Sclerosis in Canada
-
Al-Dhaher F F, Pope J E, Ouimet J M. Determinants of Morbidity and Mortality of Systemic Sclerosis in Canada. Semin Arthritis Rheum 2010, 39:269-277.
-
(2010)
Semin Arthritis Rheum
, vol.39
, pp. 269-277
-
-
Al-Dhaher, F.F.1
Pope, J.E.2
Ouimet, J.M.3
-
14
-
-
19944427793
-
Mortality in systemic sclerosis: an international meta-analysis of individual patient data
-
Ioannidis J P, Vlachoyiannopoulos P G, Haidich A B. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med 2005, 118:2-10.
-
(2005)
Am J Med
, vol.118
, pp. 2-10
-
-
Ioannidis, J.P.1
Vlachoyiannopoulos, P.G.2
Haidich, A.B.3
-
15
-
-
42449112005
-
Scleroderma Clinical Trials Consortium co-authors. Development of a provisional core set of response measures for clinical trials of systemic sclerosis
-
Khanna D, Lovell D J, Giannini E. Scleroderma Clinical Trials Consortium co-authors. Development of a provisional core set of response measures for clinical trials of systemic sclerosis. Ann Rheum Dis 2008, 67:703-709.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 703-709
-
-
Khanna, D.1
Lovell, D.J.2
Giannini, E.3
-
16
-
-
0026604019
-
Sequential dermal microvascular and perivascular changes in the development of scleroderma
-
Prescott R J, Freemont A, Jones C. Sequential dermal microvascular and perivascular changes in the development of scleroderma. J Pathol 1992, 166:255-263.
-
(1992)
J Pathol
, vol.166
, pp. 255-263
-
-
Prescott, R.J.1
Freemont, A.2
Jones, C.3
-
17
-
-
0018843919
-
Diagnostic potential of in vivo capillary microscopy in scleroderma and related disorders
-
Maricq H, LeRoy E, Dangelo W. Diagnostic potential of in vivo capillary microscopy in scleroderma and related disorders. Arthritis Rheum 1980, 23:83-189.
-
(1980)
Arthritis Rheum
, vol.23
, pp. 83-189
-
-
Maricq, H.1
LeRoy, E.2
Dangelo, W.3
-
18
-
-
0029999963
-
Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma
-
Sgonc R, Gruschwitz M, Dietrich H. Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. J Clin Invest 1996, 98:785-792.
-
(1996)
J Clin Invest
, vol.98
, pp. 785-792
-
-
Sgonc, R.1
Gruschwitz, M.2
Dietrich, H.3
-
19
-
-
0031127473
-
Mechanism of serum mediated endothelial injury in scleroderma: identification of a granular enzyme in scleroderma skin and sera
-
Kahaleh M, Fan P S. Mechanism of serum mediated endothelial injury in scleroderma: identification of a granular enzyme in scleroderma skin and sera. Clin Immunol Immunopathol 1997, 83:32-40.
-
(1997)
Clin Immunol Immunopathol
, vol.83
, pp. 32-40
-
-
Kahaleh, M.1
Fan, P.S.2
-
20
-
-
0033850755
-
Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis
-
Hebbar M, Peyrat J P, Hornez L, Hatron P Y, Hachulla E, Devulder B. Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis. Arthritis Rheum 2000, 43:889-893.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 889-893
-
-
Hebbar, M.1
Peyrat, J.P.2
Hornez, L.3
Hatron, P.Y.4
Hachulla, E.5
Devulder, B.6
-
21
-
-
0033790892
-
Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells
-
Lunardi C. Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells. Nat Med 2000, 6:1183-1186.
-
(2000)
Nat Med
, vol.6
, pp. 1183-1186
-
-
Lunardi, C.1
-
22
-
-
32044456248
-
Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: a gene array approach
-
Lunardi C, Dolcino M, Peterlana D. Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: a gene array approach. PLoS Med 2006, 3:e2.
-
(2006)
PLoS Med
, vol.3
-
-
Lunardi, C.1
Dolcino, M.2
Peterlana, D.3
-
23
-
-
39049171830
-
Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?
-
Fleming J N, Nash R A, McLeod D O. Capillary regeneration in scleroderma: stem cell therapy reverses phenotype? PLoS ONE 2008, 16:3.
-
(2008)
PLoS ONE
, vol.16
, pp. 3
-
-
Fleming, J.N.1
Nash, R.A.2
McLeod, D.O.3
-
24
-
-
67651162069
-
Hypoxia in the pathogenesis of systemic sclerosis
-
Beyer C, Schett G, Gay S, Distler O, Distler J H. Hypoxia in the pathogenesis of systemic sclerosis. Arthritis Res Ther 2009, 11:220.
-
(2009)
Arthritis Res Ther
, vol.11
, pp. 220
-
-
Beyer, C.1
Schett, G.2
Gay, S.3
Distler, O.4
Distler, J.H.5
-
25
-
-
4143072810
-
Defective vasculogenesis in systemic sclerosis
-
Kuwana M, Okazaki Y, Yasuoka H, Kawakami Y, Ikeda Y. Defective vasculogenesis in systemic sclerosis. Lancet 2004, 364:603-610.
-
(2004)
Lancet
, vol.364
, pp. 603-610
-
-
Kuwana, M.1
Okazaki, Y.2
Yasuoka, H.3
Kawakami, Y.4
Ikeda, Y.5
-
26
-
-
17544370003
-
Soluble adhesion molecules (sVCAM-1, sE-selectin), vascular endothelial growth factor (VEGF) and endothelin-1 in patients with systemic sclerosis: relationship to organ systemic involvement
-
Kuryliszyn-Moskal A, Klimiuk P A, Sierakowski S. Soluble adhesion molecules (sVCAM-1, sE-selectin), vascular endothelial growth factor (VEGF) and endothelin-1 in patients with systemic sclerosis: relationship to organ systemic involvement. Clin Rheumatol 2005, 24:111-116.
-
(2005)
Clin Rheumatol
, vol.24
, pp. 111-116
-
-
Kuryliszyn-Moskal, A.1
Klimiuk, P.A.2
Sierakowski, S.3
-
27
-
-
33947576053
-
Levels of circulating endothelial progenitor cells in systemic sclerosis
-
Allanore Y, Batteux F, Avouac J, Assous N, Weill B, Kahan A. Levels of circulating endothelial progenitor cells in systemic sclerosis. Clin Exp Rheumatol 2007, 25:60-66.
-
(2007)
Clin Exp Rheumatol
, vol.25
, pp. 60-66
-
-
Allanore, Y.1
Batteux, F.2
Avouac, J.3
Assous, N.4
Weill, B.5
Kahan, A.6
-
28
-
-
58849152850
-
EULAR Scleroderma Trials and Research group statement and recommendations on endothelial precursor cells
-
Distler J H, Allanore Y, Avouac J. EULAR Scleroderma Trials and Research group statement and recommendations on endothelial precursor cells. Ann Rheum Dis 2009, 68:163-168.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 163-168
-
-
Distler, J.H.1
Allanore, Y.2
Avouac, J.3
-
29
-
-
55849130694
-
Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions
-
Avouac J, Wipff J, Goldman O. Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions. Arthritis Rheum 2008, 58:3550-3561.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3550-3561
-
-
Avouac, J.1
Wipff, J.2
Goldman, O.3
-
30
-
-
34247564964
-
Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers
-
Distler O, Del Rosso A, Giacomelli R. Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers. Arthritis Res 2002, 4:R11.
-
(2002)
Arthritis Res
, vol.4
-
-
Distler, O.1
Del Rosso, A.2
Giacomelli, R.3
-
31
-
-
77953141647
-
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis
-
Distler O, Distler J H, Scheid A. Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circ Res 2004, 9:95.
-
(2004)
Circ Res
, vol.9
, pp. 95
-
-
Distler, O.1
Distler, J.H.2
Scheid, A.3
-
32
-
-
30744438818
-
The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis
-
Davies C A, Jeziorska M, Freemont A J, Herrick A L. The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis. Hum Pathol 2006, 37:190-197.
-
(2006)
Hum Pathol
, vol.37
, pp. 190-197
-
-
Davies, C.A.1
Jeziorska, M.2
Freemont, A.J.3
Herrick, A.L.4
-
33
-
-
26644440414
-
Interleukin 4 and prolonged hypoxia induce a higher gene expression of lysyl hydroxylase 2 and an altered cross-link pattern: important pathogenetic steps in early and late stage of systemic scleroderma?
-
Brinckmann J, Kim S, Wu J. Interleukin 4 and prolonged hypoxia induce a higher gene expression of lysyl hydroxylase 2 and an altered cross-link pattern: important pathogenetic steps in early and late stage of systemic scleroderma? Matrix Biol 2005, 24:459-468.
-
(2005)
Matrix Biol
, vol.24
, pp. 459-468
-
-
Brinckmann, J.1
Kim, S.2
Wu, J.3
-
34
-
-
37149006718
-
Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis
-
Distler J H, Jüngel A, Pileckyte M. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. Arthritis Rheum 2007, 56:4203-4215.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4203-4215
-
-
Distler, J.H.1
Jüngel, A.2
Pileckyte, M.3
-
35
-
-
33750083588
-
Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts
-
Hong K H, Yoo S A, Kang S S, Choi J J, Kim W U, Cho C S. Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts. Clin Exp Immunol 2006, 146:362-370.
-
(2006)
Clin Exp Immunol
, vol.146
, pp. 362-370
-
-
Hong, K.H.1
Yoo, S.A.2
Kang, S.S.3
Choi, J.J.4
Kim, W.U.5
Cho, C.S.6
-
36
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
Higgins D F, Kimura K, Bernhardt W M. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 2007, 117:3810-3820.
-
(2007)
J Clin Invest
, vol.117
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt, W.M.3
-
37
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S, Derynck R. TGF-beta-induced epithelial to mesenchymal transition. Cell Res 2009, 19:156-172.
-
(2009)
Cell Res
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
38
-
-
0034837756
-
Effects of long-term cyclic iloprost therapy in systemic sclerosis with Raynaud's phenomenon. A randomized, controlled study
-
Scorza R, Caronni M, Mascagni B. Effects of long-term cyclic iloprost therapy in systemic sclerosis with Raynaud's phenomenon. A randomized, controlled study. Clin Exp Rheumatol 2001, 19:503-508.
-
(2001)
Clin Exp Rheumatol
, vol.19
, pp. 503-508
-
-
Scorza, R.1
Caronni, M.2
Mascagni, B.3
-
39
-
-
62649152815
-
Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors
-
Sunderkötter C, Herrgott I, Brückner C. Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors. Br J Dermatol 2009, 160:835-843.
-
(2009)
Br J Dermatol
, vol.160
, pp. 835-843
-
-
Sunderkötter, C.1
Herrgott, I.2
Brückner, C.3
-
40
-
-
37849012578
-
BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King T E, Behr J, Brown K K. BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008, 1:177.
-
(2008)
Am J Respir Crit Care Med
, vol.1
, pp. 177
-
-
King, T.E.1
Behr, J.2
Brown, K.K.3
-
41
-
-
18344396051
-
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
-
Zuo F, Kaminski N, Eugui E. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA 2002, 99:6292-6297.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6292-6297
-
-
Zuo, F.1
Kaminski, N.2
Eugui, E.3
-
42
-
-
72549108357
-
Tumor necrosis factor-alpha processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma
-
Terao M, Murota H, Kitaba S, Katayama I. Tumor necrosis factor-alpha processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma. Exp Dermatol 2010, 18:38-43.
-
(2010)
Exp Dermatol
, vol.18
, pp. 38-43
-
-
Terao, M.1
Murota, H.2
Kitaba, S.3
Katayama, I.4
-
43
-
-
2442694270
-
Pivotal role of cathepsin K in lung fibrosis
-
Buhling F, Rocken C, Brasch F. Pivotal role of cathepsin K in lung fibrosis. Am J Pathol 2004, 164:2203-2216.
-
(2004)
Am J Pathol
, vol.164
, pp. 2203-2216
-
-
Buhling, F.1
Rocken, C.2
Brasch, F.3
-
44
-
-
17044454221
-
Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis
-
van der Slot A J, Zuurmond A M, Bardoel A F. Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis. J Biol Chem 2003, 278:40967-40972.
-
(2003)
J Biol Chem
, vol.278
, pp. 40967-40972
-
-
van der Slot, A.J.1
Zuurmond, A.M.2
Bardoel, A.F.3
-
45
-
-
0032406845
-
Increased circulating concentrations of the type I collagen specific degradation product ICTP in systemic sclerosis reflect the extent of skin involvement: a new serum marker for clinical severity in SSc patients
-
Hunzelmann N, Risteli J, Risteli L, Sacher C, Black C M, Krieg T. Increased circulating concentrations of the type I collagen specific degradation product ICTP in systemic sclerosis reflect the extent of skin involvement: a new serum marker for clinical severity in SSc patients. Br J Dermatol 1998, 139:1020-1025.
-
(1998)
Br J Dermatol
, vol.139
, pp. 1020-1025
-
-
Hunzelmann, N.1
Risteli, J.2
Risteli, L.3
Sacher, C.4
Black, C.M.5
Krieg, T.6
-
46
-
-
12244264813
-
Correlation of serum collagen I carboxyterminal telopeptide concentrations with cutaneous and pulmonary involvement in systemic sclerosis
-
Allanore Y, Borderie D, Lemaréchal H, Cherruau B, Ekindjian O G, Kahan A. Correlation of serum collagen I carboxyterminal telopeptide concentrations with cutaneous and pulmonary involvement in systemic sclerosis. J Rheumatol 2003, 30:68-73.
-
(2003)
J Rheumatol
, vol.30
, pp. 68-73
-
-
Allanore, Y.1
Borderie, D.2
Lemaréchal, H.3
Cherruau, B.4
Ekindjian, O.G.5
Kahan, A.6
-
47
-
-
77953170845
-
Autologous peripheral blood stem cell transplantation for systemic sclerosis - C-terminal collagen telopeptide serum levels as a biomarker for reduction of fibrosis and clinical improvement
-
Kötter I, Henes J, Koch S, Kanz L, Hunzelmann N. Autologous peripheral blood stem cell transplantation for systemic sclerosis - C-terminal collagen telopeptide serum levels as a biomarker for reduction of fibrosis and clinical improvement. Ann Rheum Dis 2007, 66(Suppl. II):213.
-
(2007)
Ann Rheum Dis
, vol.66
, Issue.2 SUPPL.
, pp. 213
-
-
Kötter, I.1
Henes, J.2
Koch, S.3
Kanz, L.4
Hunzelmann, N.5
-
48
-
-
33745042859
-
Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts
-
Gardner H, Shearstone J R, Bandaru R. Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts. Arthritis Rheum 2006, 54:1961-1973.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1961-1973
-
-
Gardner, H.1
Shearstone, J.R.2
Bandaru, R.3
-
49
-
-
49949114547
-
Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin
-
Milano A, Pendergrass S A, Sargent J L. Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin. PLoS ONE 2008, 3:e2696.
-
(2008)
PLoS ONE
, vol.3
-
-
Milano, A.1
Pendergrass, S.A.2
Sargent, J.L.3
-
50
-
-
0028040486
-
Localization of endothelin-1 and its binding sites in scleroderma skin
-
Vancheeswaran R, Azam A, Black C, Dashwood M R. Localization of endothelin-1 and its binding sites in scleroderma skin. J Rheumatol 2004, 21:1268-1276.
-
(2004)
J Rheumatol
, vol.21
, pp. 1268-1276
-
-
Vancheeswaran, R.1
Azam, A.2
Black, C.3
Dashwood, M.R.4
-
51
-
-
77953173150
-
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK
-
Xu S W, Howat S L, Renzoni E A. Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK. J Biol Chem 2004, 28:279.
-
(2004)
J Biol Chem
, vol.28
, pp. 279
-
-
Xu, S.W.1
Howat, S.L.2
Renzoni, E.A.3
-
52
-
-
29144492719
-
Signalling and regulation of collagen I synthesis by ET-1 and TGF-beta 1
-
Horstmeyer A, Licht C, Scherr G, Eckes G, Krieg T. Signalling and regulation of collagen I synthesis by ET-1 and TGF-beta 1. FEBS J 2005, 272:6297-6309.
-
(2005)
FEBS J
, vol.272
, pp. 6297-6309
-
-
Horstmeyer, A.1
Licht, C.2
Scherr, G.3
Eckes, G.4
Krieg, T.5
-
53
-
-
59649083980
-
Alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?
-
Kokot A, Sindrilaru A, Schiller M. alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma? Arthritis Rheum 2009, 60:592-603.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 592-603
-
-
Kokot, A.1
Sindrilaru, A.2
Schiller, M.3
-
54
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
Iwano M, Plieth D, Danoff T M, Xue C, Okada H, Nielson E G. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002, 110:341-350.
-
(2002)
J Clin Invest
, vol.110
, pp. 341-350
-
-
Iwano, M.1
Plieth, D.2
Danoff, T.M.3
Xue, C.4
Okada, H.5
Nielson, E.G.6
-
55
-
-
34547676391
-
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
-
Zeisberg E M, Tarnavaski O, Zeisberg M. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med 2007, 13:952-961.
-
(2007)
Nat Med
, vol.13
, pp. 952-961
-
-
Zeisberg, E.M.1
Tarnavaski, O.2
Zeisberg, M.3
-
56
-
-
34247533369
-
Phenotypic transitions and fibrosis in diabetic nephropathy
-
Simonson M S. Phenotypic transitions and fibrosis in diabetic nephropathy. Kidney Int 2007, 71:846-854.
-
(2007)
Kidney Int
, vol.71
, pp. 846-854
-
-
Simonson, M.S.1
-
57
-
-
34547960749
-
The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses
-
Bellini A, Mattoli S. The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses. Lab Invest 2007, 87:858-870.
-
(2007)
Lab Invest
, vol.87
, pp. 858-870
-
-
Bellini, A.1
Mattoli, S.2
-
58
-
-
33846086980
-
Transforming growth factor-beta: innately bipolar
-
Wahl S M. Transforming growth factor-beta: innately bipolar. Curr Opin Immunol 2007, 19:55-62.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 55-62
-
-
Wahl, S.M.1
-
59
-
-
2142646426
-
TGF-beta signaling and the fibrotic response
-
Leask A, Abraham D J. TGF-beta signaling and the fibrotic response. FASEB J 2004, 18:816-827.
-
(2004)
FASEB J
, vol.18
, pp. 816-827
-
-
Leask, A.1
Abraham, D.J.2
-
60
-
-
34948826895
-
Molecular pathways as novel therapeutic targets in systemic sclerosis
-
Trojanowska M, Varga J. Molecular pathways as novel therapeutic targets in systemic sclerosis. Curr Opin Rheumatol 2007, 19:568-573.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 568-573
-
-
Trojanowska, M.1
Varga, J.2
-
61
-
-
0035089825
-
Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors
-
Ihn H, Yamane K, Kubo M, Tamaki K. Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors. Arthritis Rheum 2001, 44:474-480.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 474-480
-
-
Ihn, H.1
Yamane, K.2
Kubo, M.3
Tamaki, K.4
-
62
-
-
0031886413
-
Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype
-
Kawakami T, Ihn H, Xu W, Smith E, LeRoy C, Trojanowska M. Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype. J Invest Dermatol 1998, 110:47-51.
-
(1998)
J Invest Dermatol
, vol.110
, pp. 47-51
-
-
Kawakami, T.1
Ihn, H.2
Xu, W.3
Smith, E.4
LeRoy, C.5
Trojanowska, M.6
-
63
-
-
0029905441
-
Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
-
Isaka Y, Brees D K, Ikegaya K. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat Med 1996, 2:418-423.
-
(1996)
Nat Med
, vol.2
, pp. 418-423
-
-
Isaka, Y.1
Brees, D.K.2
Ikegaya, K.3
-
64
-
-
0033571072
-
Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma
-
McCormick L L, Zhang Y, Tootell E, Gilliam A C. Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma. J Immunol 1999, 163:5693-5699.
-
(1999)
J Immunol
, vol.163
, pp. 5693-5699
-
-
McCormick, L.L.1
Zhang, Y.2
Tootell, E.3
Gilliam, A.C.4
-
65
-
-
27144458232
-
Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis
-
Santiago B, Gutierrez-Canas I, Dotor J. Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis. J Invest Dermatol 2005, 125:450-455.
-
(2005)
J Invest Dermatol
, vol.125
, pp. 450-455
-
-
Santiago, B.1
Gutierrez-Canas, I.2
Dotor, J.3
-
66
-
-
77953150350
-
A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats
-
Hermida N, López B, González A. A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats. Cardiovasc Res 2009, 15:81.
-
(2009)
Cardiovasc Res
, vol.15
, pp. 81
-
-
Hermida, N.1
López, B.2
González, A.3
-
67
-
-
3042550759
-
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma
-
Lakos G, Takagawa S, Chen S J. Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am J Pathol 2004, 165:203-217.
-
(2004)
Am J Pathol
, vol.165
, pp. 203-217
-
-
Lakos, G.1
Takagawa, S.2
Chen, S.J.3
-
68
-
-
0041342109
-
Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery
-
Mead A L, Wong T T, Cordeiro M F, Anderson I K, Khaw P T. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci 2003, 44:3394-3401.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3394-3401
-
-
Mead, A.L.1
Wong, T.T.2
Cordeiro, M.F.3
Anderson, I.K.4
Khaw, P.T.5
-
69
-
-
34748861947
-
A phase III study of subconjunctival human anti-transforming growth factor beta (2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy
-
Khaw P, Grehn F. A phase III study of subconjunctival human anti-transforming growth factor beta (2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy. Ophthalmology 2007, 114:1822-1830.
-
(2007)
Ophthalmology
, vol.114
, pp. 1822-1830
-
-
Khaw, P.1
Grehn, F.2
-
70
-
-
33846250366
-
Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192
-
Denton C P, Merkel P A, Furst D E. Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192. Arthritis Rheum 2007, 56:323-333.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 323-333
-
-
Denton, C.P.1
Merkel, P.A.2
Furst, D.E.3
et al4
-
71
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
Heldin C-H, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999, 79:1283-1316.
-
(1999)
Physiol Rev
, vol.79
, pp. 1283-1316
-
-
Heldin, C.-H.1
Westermark, B.2
-
72
-
-
0032462002
-
Evidence for distinct signaling properties and biological responses induced by the PDGF receptor α and β subtypes
-
Rosenkranz S, Kazlauskas A. Evidence for distinct signaling properties and biological responses induced by the PDGF receptor α and β subtypes. Growth Factors 1999, 16:201-216.
-
(1999)
Growth Factors
, vol.16
, pp. 201-216
-
-
Rosenkranz, S.1
Kazlauskas, A.2
-
73
-
-
17144386566
-
Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells: only phosphatidylinositol 3′-kinase is important
-
Vantler M, Caglayan E, Zimmermann W H, Bäumer A T, Rosenkranz S. Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells: only phosphatidylinositol 3′-kinase is important. J Biol Chem 2005, 280:14168-14176.
-
(2005)
J Biol Chem
, vol.280
, pp. 14168-14176
-
-
Vantler, M.1
Caglayan, E.2
Zimmermann, W.H.3
Bäumer, A.T.4
Rosenkranz, S.5
-
74
-
-
26444540768
-
Reversal of experimental pulmonary hypertension by PDGF inhibition
-
Schermuly R T, Dony E, Ghofrani H A. Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clin Invest 2005, 115:2811-2821.
-
(2005)
J Clin Invest
, vol.115
, pp. 2811-2821
-
-
Schermuly, R.T.1
Dony, E.2
Ghofrani, H.A.3
-
75
-
-
59649093844
-
Increased PDGFRα Activation Disrupts Connective Tissue Development and Drives Systemic Fibrosis
-
Olson L E, Soriano P. Increased PDGFRα Activation Disrupts Connective Tissue Development and Drives Systemic Fibrosis. Dev Cell 2009, 16:303-313.
-
(2009)
Dev Cell
, vol.16
, pp. 303-313
-
-
Olson, L.E.1
Soriano, P.2
-
76
-
-
33745277147
-
Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis
-
Baroni S S, Santillo M, Bevilacqua F. Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis. N Engl J Med 2006, 354:2667-2676.
-
(2006)
N Engl J Med
, vol.354
, pp. 2667-2676
-
-
Baroni, S.S.1
Santillo, M.2
Bevilacqua, F.3
-
77
-
-
34347386226
-
Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease
-
Svegliati S, Olivieri A, Campelli N. Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease. Blood 2007, 1:110.
-
(2007)
Blood
, vol.1
, pp. 110
-
-
Svegliati, S.1
Olivieri, A.2
Campelli, N.3
-
78
-
-
65249166538
-
Stimulatory autoantibodies to platelet-derived growth factor receptors in systemic sclerosis: what functional autoimmunity could learn from receptor biology
-
Dragun D, Distler J H, Riemekasten G, Distler O. Stimulatory autoantibodies to platelet-derived growth factor receptors in systemic sclerosis: what functional autoimmunity could learn from receptor biology. Arthritis Rheum 2009, 60:907-911.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 907-911
-
-
Dragun, D.1
Distler, J.H.2
Riemekasten, G.3
Distler, O.4
-
79
-
-
0035064803
-
The CCN family of genes: a brief history
-
Perbal B. The CCN family of genes: a brief history. Mol Pathol 2001, 54:103-104.
-
(2001)
Mol Pathol
, vol.54
, pp. 103-104
-
-
Perbal, B.1
-
80
-
-
0029816069
-
Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
-
Frazier K, Williams S, Kothapalli D, Klapper H, Grotendorst G R. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 1996, 107:404-411.
-
(1996)
J Invest Dermatol
, vol.107
, pp. 404-411
-
-
Frazier, K.1
Williams, S.2
Kothapalli, D.3
Klapper, H.4
Grotendorst, G.R.5
-
81
-
-
0029996247
-
Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders
-
Igarashi A, Nashiro K, Kikuchi K. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 1996, 106:729-733.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 729-733
-
-
Igarashi, A.1
Nashiro, K.2
Kikuchi, K.3
-
82
-
-
0035161153
-
Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis
-
Denton C P, Abraham D J. Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis. Curr Opin Rheumatol 2001, 13:505-511.
-
(2001)
Curr Opin Rheumatol
, vol.13
, pp. 505-511
-
-
Denton, C.P.1
Abraham, D.J.2
-
83
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn T A. Cellular and molecular mechanisms of fibrosis. J Pathol 2008, 214:199-210.
-
(2008)
J Pathol
, vol.214
, pp. 199-210
-
-
Wynn, T.A.1
-
85
-
-
77953173512
-
Imatinib for the treatment of pulmonary arterial hypertension
-
Ghofrani H A, Seeger W, Grimminger F. Imatinib for the treatment of pulmonary arterial hypertension. N Engl J Med 2005, 29:353.
-
(2005)
N Engl J Med
, vol.29
, pp. 353
-
-
Ghofrani, H.A.1
Seeger, W.2
Grimminger, F.3
-
86
-
-
36348930435
-
Marrow fibrosis and its relevance during imatinib treatment of chronic myeloid leukemia
-
Buesche G, Ganser A, Schlegelberger B. Marrow fibrosis and its relevance during imatinib treatment of chronic myeloid leukemia. Leukemia 2007, 21:2420-2427.
-
(2007)
Leukemia
, vol.21
, pp. 2420-2427
-
-
Buesche, G.1
Ganser, A.2
Schlegelberger, B.3
-
87
-
-
33846209989
-
Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
-
Distler J H, Jüngel A, Huber L C. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum 2007, 56:311-322.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 311-322
-
-
Distler, J.H.1
Jüngel, A.2
Huber, L.C.3
-
88
-
-
46749154199
-
Dual inhibition of c-abl and PDGF receptor signaling by datatinib and nilotinib for the treatment of dermal fibrosis
-
Akhmetshina A, Dees C, Pileckyte M. Dual inhibition of c-abl and PDGF receptor signaling by datatinib and nilotinib for the treatment of dermal fibrosis. FASEB J 2008, 22:2214-2222.
-
(2008)
FASEB J
, vol.22
, pp. 2214-2222
-
-
Akhmetshina, A.1
Dees, C.2
Pileckyte, M.3
-
89
-
-
58249120518
-
Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of fibrosis
-
Akhmetshina A, Venalis P, Dees C. Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of fibrosis. Arthritis Rheum 2009, 60:219-224.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 219-224
-
-
Akhmetshina, A.1
Venalis, P.2
Dees, C.3
-
90
-
-
42949167686
-
Imatinib for the treatment of refractory, diffuse systemic sclerosis
-
Sfikakis P P, Gorgoulis V G, Katsiari C G. Imatinib for the treatment of refractory, diffuse systemic sclerosis. Rheumatology (Oxford) 2008, 47:735-737.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 735-737
-
-
Sfikakis, P.P.1
Gorgoulis, V.G.2
Katsiari, C.G.3
-
91
-
-
49449090687
-
Treatment of pulmonary fibrosis for twenty weeks with imatinib mesylate in a patient with mixed connective tissue disease
-
Distler J H, Manger B, Spriewald B M, Schett G, Distler O. Treatment of pulmonary fibrosis for twenty weeks with imatinib mesylate in a patient with mixed connective tissue disease. Arthritis Rheum 2008, 58:2538-2542.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2538-2542
-
-
Distler, J.H.1
Manger, B.2
Spriewald, B.M.3
Schett, G.4
Distler, O.5
-
92
-
-
77953157458
-
Imatinib mesylate as salvage therapy for refractory sclerotic chronic graft-versus-host disease
-
Magro L, Mohty M, Catteau B. Imatinib mesylate as salvage therapy for refractory sclerotic chronic graft-versus-host disease. Blood 2009, 16:114.
-
(2009)
Blood
, vol.16
, pp. 114
-
-
Magro, L.1
Mohty, M.2
Catteau, B.3
-
93
-
-
0034881149
-
D-penicillamine is not an effective treatment in systemic sclerosis
-
Furst D E, Clements P J. D-penicillamine is not an effective treatment in systemic sclerosis. Scand J Rheumatol 2001, 30:189-191.
-
(2001)
Scand J Rheumatol
, vol.30
, pp. 189-191
-
-
Furst, D.E.1
Clements, P.J.2
-
94
-
-
0034970031
-
A randomized controlled trial of methotrexate versus placebo in early diffuse scleroderma
-
Pope J, Bellamy N, Seibold J. A randomized controlled trial of methotrexate versus placebo in early diffuse scleroderma. Arthritis Rheum 2001, 44:1351-1358.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1351-1358
-
-
Pope, J.1
Bellamy, N.2
Seibold, J.3
-
95
-
-
77953146389
-
Alternate trafficking of cathepsin L in dermal fibroblasts induced by UVA radiation
-
DOI: 10.1111/j.1600-0625.2009.01014.x, (Epub ahead of print)
-
Klose A, Wilbrand-Hennes A, Brinckmann J, Hunzelmann N. Alternate trafficking of cathepsin L in dermal fibroblasts induced by UVA radiation. Exp Dermatol 2010, 10.1111/j.1600-0625.2009.01014.x, DOI, (Epub ahead of print)
-
(2010)
Exp Dermatol
-
-
Klose, A.1
Wilbrand-Hennes, A.2
Brinckmann, J.3
Hunzelmann, N.4
-
96
-
-
0035723147
-
Different patterns of collagen cross-links in two sclerotic skin diseases: lipodermatosclerosis and circumscribed scleroderma
-
Brinckmann J, Neess C M, Gaber Y. Different patterns of collagen cross-links in two sclerotic skin diseases: lipodermatosclerosis and circumscribed scleroderma. J Invest Dermatol 2001, 117:269-273.
-
(2001)
J Invest Dermatol
, vol.117
, pp. 269-273
-
-
Brinckmann, J.1
Neess, C.M.2
Gaber, Y.3
-
97
-
-
33748998739
-
Phototherapy: a promising treatment option for skin sclerosis in scleroderma?
-
Sunderkötter C, Kuhn A, Hunzelmann N, Beissert S. Phototherapy: a promising treatment option for skin sclerosis in scleroderma? Rheumatology 2006, 45:iii52-iii54.
-
(2006)
Rheumatology
, vol.45
-
-
Sunderkötter, C.1
Kuhn, A.2
Hunzelmann, N.3
Beissert, S.4
-
98
-
-
22544456889
-
Anti-B- cell-directed immunotherapy (rituximab) in the treatment of refractory pemphigus--an update
-
Arin M J, Hunzelmann N. Anti-B- cell-directed immunotherapy (rituximab) in the treatment of refractory pemphigus--an update. Eur J Dermatol 2005, 15:224-230.
-
(2005)
Eur J Dermatol
, vol.15
, pp. 224-230
-
-
Arin, M.J.1
Hunzelmann, N.2
-
99
-
-
47249144728
-
Induction of interferon-a by scleroderma sera containing autoantibodies to topoisomerase I
-
Kim D, Peck A, Santer D. Induction of interferon-a by scleroderma sera containing autoantibodies to topoisomerase I. Arthritis Rheum 2008, 58:2163-2173.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2163-2173
-
-
Kim, D.1
Peck, A.2
Santer, D.3
-
100
-
-
77953168209
-
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection
-
Dragun D, Müller D N, Bräsen J H. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med 2005, 10:352.
-
(2005)
N Engl J Med
, vol.10
, pp. 352
-
-
Dragun, D.1
Müller, D.N.2
Bräsen, J.H.3
-
101
-
-
49149112861
-
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice
-
Zhou C C, Zhang Y, Irani R A. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat Med 2008, 14:855-862.
-
(2008)
Nat Med
, vol.14
, pp. 855-862
-
-
Zhou, C.C.1
Zhang, Y.2
Irani, R.A.3
-
102
-
-
69949164465
-
Is preeclampsia an autoimmune disease?
-
Xia Y, Kellems R E. Is preeclampsia an autoimmune disease? Clin Immunol 2009, 133:1-12.
-
(2009)
Clin Immunol
, vol.133
, pp. 1-12
-
-
Xia, Y.1
Kellems, R.E.2
-
103
-
-
35148878346
-
Elevated serum APRIL levels in patients with systemic sclerosis: distinct profiles of systemic sclerosis categorized by APRIL and BAFF
-
Matsushita T, Fujimoto M, Hasegawa M. Elevated serum APRIL levels in patients with systemic sclerosis: distinct profiles of systemic sclerosis categorized by APRIL and BAFF. J Rheumatol 2007, 34:2056-2062.
-
(2007)
J Rheumatol
, vol.34
, pp. 2056-2062
-
-
Matsushita, T.1
Fujimoto, M.2
Hasegawa, M.3
-
104
-
-
34848833579
-
B cell infiltration in systemic sclerosis-associated interstitial lung disease
-
Lafyatis R, O'Hara C, Feghali-Bostwick C A, Matteson E. B cell infiltration in systemic sclerosis-associated interstitial lung disease. Arthritis Rheum 2007, 56:3167-3168.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3167-3168
-
-
Lafyatis, R.1
O'Hara, C.2
Feghali-Bostwick, C.A.3
Matteson, E.4
-
105
-
-
0036262665
-
CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse
-
Saito E, Fujimoto M, Hasegawa M. CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse. J Clin Invest 2002, 109:1453-1462.
-
(2002)
J Clin Invest
, vol.109
, pp. 1453-1462
-
-
Saito, E.1
Fujimoto, M.2
Hasegawa, M.3
-
106
-
-
33748788266
-
B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis
-
Hasegawa M, Hamaguchi Y, Yanaba K. B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. Am J Pathol 2006, 169:954-966.
-
(2006)
Am J Pathol
, vol.169
, pp. 954-966
-
-
Hasegawa, M.1
Hamaguchi, Y.2
Yanaba, K.3
-
107
-
-
41849147093
-
Discordant response to rituximab in a systemic sclerosis patient with associated myositis
-
Fabri M, Hunzelmann N, Krieg T, Rubbert A. Discordant response to rituximab in a systemic sclerosis patient with associated myositis. J Am Acad Dermatol 2008, 58(5 Suppl. 1):127-128.
-
(2008)
J Am Acad Dermatol
, vol.58
, Issue.5 SUPPL. 1
, pp. 127-128
-
-
Fabri, M.1
Hunzelmann, N.2
Krieg, T.3
Rubbert, A.4
-
108
-
-
59649109772
-
B Cell Depletion With Rituximab in Patients With Diffuse Cutaneous Systemic Sclerosis
-
Lafyatis R, Kissin E, York M. B Cell Depletion With Rituximab in Patients With Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheum 2009, 60:578-583.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 578-583
-
-
Lafyatis, R.1
Kissin, E.2
York, M.3
-
109
-
-
73449095775
-
Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study
-
Smith V, Van Praet J T, Vandooren B R. Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study. Ann Rheum Dis 2010, 69:193-197.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 193-197
-
-
Smith, V.1
Van Praet, J.T.2
Vandooren, B.R.3
-
110
-
-
56749098376
-
How to cope with pathogenic long-lived plasma cells in autoimmune diseases
-
Hoyer B F, Mumtaz I M, Yoshida T, Hiepe F, Radbruch A. How to cope with pathogenic long-lived plasma cells in autoimmune diseases. Ann Rheum Dis 2008, 67(Suppl. 3):iii87-iii89.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.3 SUPPL.
-
-
Hoyer, B.F.1
Mumtaz, I.M.2
Yoshida, T.3
Hiepe, F.4
Radbruch, A.5
-
111
-
-
34948847074
-
Adult stem cell treatment of scleroderma
-
Tyndall A, Furst D E. Adult stem cell treatment of scleroderma. Curr Opin Rheumatol 2007, 19:604-610.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 604-610
-
-
Tyndall, A.1
Furst, D.E.2
-
112
-
-
0035017415
-
Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease
-
Binks M, Passweg J R, Furst D. Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease. Ann Rheum Dis 2001, 60:577-584.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 577-584
-
-
Binks, M.1
Passweg, J.R.2
Furst, D.3
-
113
-
-
18744364686
-
Autologous bone marrow transplantation in the treatment of refractory systemic sclerosis: early results from a French multicentre phase I-II study
-
Farge D, Marolleau J P, Zohar S. Autologous bone marrow transplantation in the treatment of refractory systemic sclerosis: early results from a French multicentre phase I-II study. Br J Haematol 2002, 119:726-739.
-
(2002)
Br J Haematol
, vol.119
, pp. 726-739
-
-
Farge, D.1
Marolleau, J.P.2
Zohar, S.3
-
114
-
-
37749001089
-
Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis
-
Vonk M C, Marjanovic Z, van den Hoogen F H. Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis. Ann Rheum Dis 2008, 67:98-104.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 98-104
-
-
Vonk, M.C.1
Marjanovic, Z.2
van den Hoogen, F.H.3
-
115
-
-
33745040938
-
Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis
-
Nash R A, McSweeney P A, Nelson J L. Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis. Arthritis Rheum 2006, 54:1982-1986.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1982-1986
-
-
Nash, R.A.1
McSweeney, P.A.2
Nelson, J.L.3
|