Regulation of retinal function but nonrescue of vision in rpe65-deficient dogs treated with doxycycline-regulatable AAV vectors

Molecular Therapy

Volumn 18, Issue 6, 2010, Pages 1085-1093

  Lhériteau, Elsa ^a   Libeau, Lyse ^a   Mendes Madeira, Alexandra ^a   Deschamps, Jack Yves ^b   Weber, Michel ^c   Le Meur, Guylène ^c   Provost, Nathalie ^a   Guihal, Caroline ^a   Moullier, Philippe ^a,d   Rolling, Fabienne ^a  

^a UNIVERSITÉ DE NANTES   (France)

^b LUNAM UNIVERSITÉ   (France)

^c HÔTEL DIEU   (France)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; PARVOVIRUS VECTOR; RETINA PIGMENT EPITHELIUM PROTEIN 65; UNCLASSIFIED DRUG; VISUAL PIGMENT; EYE PROTEIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOG; ELECTRORETINOGRAPHY; GENE REGULATORY NETWORK; NONHUMAN; PIGMENT EPITHELIUM; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; VISION; ANIMAL; DEPENDOPARVOVIRUS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; PATHOPHYSIOLOGY; RETINA; VISION DISORDERS;

ADENO-ASSOCIATED VIRUS; CANIS FAMILIARIS; CYTOMEGALOVIRUS; PRIMATES;

ANIMALS; DEPENDOVIRUS; DOGS; DOXYCYCLINE; EYE PROTEINS; GENE EXPRESSION REGULATION; GENETIC VECTORS; RETINA; VISION DISORDERS;

EID: 77953130993     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.46     Document Type: Article

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