High affinity of sigma1-binding sites for sterol isomerization inhibitors: Evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase

British Journal of Pharmacology

Volumn 121, Issue 1, 1997, Pages 1-6

  Moebius, Fabian F ^a   Reiter, Raphael J ^a   Hanner, Markus ^a,b   Glossmann, Hartmut ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

AY 9944; Cholesterol; Clomiphene; ERG2; Ergosterol; Fenpropimorph; Sigma1 binding site; Sterol C8 C7 isomerase; Tamoxifen; Triparanol

Indexed keywords

1,4 BIS(2 CHLOROBENZYLAMINOMETHYL)CYCLOHEXANE; ANTIESTROGEN; CLOMIFENE; EMOPAMIL; FENPROPIMORPH; FUNGICIDE; HYPOCHOLESTEROLEMIC AGENT; ISOMERASE; MDL 28815; PENTAZOCINE; STEROL; TAMOXIFEN; TRIPARANOL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; GUINEA PIG; ISOMERISM; LIVER; NONHUMAN; PRIORITY JOURNAL;

EID: 0030933902     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701079     Document Type: Article

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