Adventures in time and space: Nonlinearity and complexity of cytokine effects on stem cell fate decisions

Biotechnology and Bioengineering

Volumn 106, Issue 2, 2010, Pages 173-182

  Audet, Julie ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Factorial design experiments; Growth factors; Multivariate analysis; Process optimization; Stem cells

Indexed keywords

FACTORIAL DESIGN; FACTORIAL DESIGN EXPERIMENTS; GROWTH FACTOR; MULTI VARIATE ANALYSIS; PROCESS OPTIMIZATION;

ASSOCIATION REACTIONS; BIOACTIVITY; CELL CULTURE; CELL PROLIFERATION; DECISION MAKING; DESIGN; EXPERIMENTS; LINEAR REGRESSION; MULTIVARIANT ANALYSIS; OPTIMIZATION; PEPTIDES; PROCESS CONTROL; SIGNALING;

STEM CELLS;

ACTIVIN A; BONE MORPHOGENETIC PROTEIN; CYTOKINE; CYTOKINE RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 4; FIBRONECTIN; INTERLEUKIN 3; LEUKEMIA INHIBITORY FACTOR; MATRIX PROTEIN; STEM CELL FACTOR RECEPTOR; THROMBOPOIETIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

CELL CULTURE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CYTOKINE PRODUCTION; ECTODERM; EMBRYONIC STEM CELL; ERYTHROBLAST; ERYTHROCYTE; ERYTHROID CELL; EXPERIMENTAL DESIGN; EXTRACELLULAR MATRIX; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIPID RAFT; LOG RANK TEST; MATHEMATICAL MODEL; MEGAKARYOCYTE ERYTHROID PROGENITOR; MULTIPLE LINEAR REGRESSION ANALYSIS; NONHUMAN; PLEIOTROPY; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL EXPANSION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; HUMANS; MODELS, IMMUNOLOGICAL; NONLINEAR DYNAMICS; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 77953056530     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22708     Document Type: Review

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