Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer's disease neuropathology

Acta Neuropathologica

Volumn 119, Issue 5, 2010, Pages 543-554

  Hashimoto, Masakazu ^a   Bogdanovic, Nenad ^b   Volkmann, Inga ^a   Aoki, Mikio ^a,c   Winblad, Bengt ^a   Tjernberg, Lars O ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

A 40; A 42; Alzheimer's disease; ELISA; Laser capture microdissection; Purkinje neuron

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42];

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN NERVE CELL; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE PREDISPOSITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION MICROSCOPY; MALE; MICROSCOPY; NEUROPATHOLOGY; PRIORITY JOURNAL; PURKINJE CELL; PYRAMIDAL NERVE CELL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CEREBELLUM; CYTOPLASM; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MICRODISSECTION; PEPTIDE FRAGMENTS; PURKINJE CELLS; PYRAMIDAL CELLS;

EID: 77953024447     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0661-6     Document Type: Article

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