-
1
-
-
34247214427
-
Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA
-
Alami, M., Dalal, K., Lelj-Garolla, B., Sligar, S., Duong, F., Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA. EMBO J. 26 (2007), 1995–2004.
-
(2007)
EMBO J.
, vol.26
, pp. 1995-2004
-
-
Alami, M.1
Dalal, K.2
Lelj-Garolla, B.3
Sligar, S.4
Duong, F.5
-
2
-
-
2442626615
-
Implications of the allosteric kinetics of cytochrome P450s
-
Atkins, W., Implications of the allosteric kinetics of cytochrome P450s. Drug Discov. Today 9 (2004), 478–484.
-
(2004)
Drug Discov. Today
, vol.9
, pp. 478-484
-
-
Atkins, W.1
-
3
-
-
0022539462
-
Recombinant lipoproteins—Implications for structure and assembly of native lipoproteins
-
Atkinson, D., Small, D., Recombinant lipoproteins—Implications for structure and assembly of native lipoproteins. Annu. Rev. Biophys. Biol. 15 (1986), 403–456.
-
(1986)
Annu. Rev. Biophys. Biol.
, vol.15
, pp. 403-456
-
-
Atkinson, D.1
Small, D.2
-
4
-
-
0019494948
-
Cell-substrate contacts illuminated by total internal reflection fluorescence
-
Axelrod, D., Cell-substrate contacts illuminated by total internal reflection fluorescence. J. Cell Biol. 89 (1981), 141–145.
-
(1981)
J. Cell Biol.
, vol.89
, pp. 141-145
-
-
Axelrod, D.1
-
5
-
-
4444297536
-
Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment
-
Baas, B., Denisov, I., Sligar, S., Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment. Arch. Biochem. Biophys. 430 (2004), 218–228.
-
(2004)
Arch. Biochem. Biophys.
, vol.430
, pp. 218-228
-
-
Baas, B.1
Denisov, I.2
Sligar, S.3
-
6
-
-
67650564177
-
Hydrogen production by a hyperthermophilic membrane-bound hydrogenase in water-soluble nanolipoprotein particles
-
Baker, S., Hopkins, R., Blanchette, C., Walsworth, V., Sumbad, R., Fischer, N., Kuhn, E., Coleman, M., Chromy, B., Letant, S., Hoeprich, P., Adams, M., et al. Hydrogen production by a hyperthermophilic membrane-bound hydrogenase in water-soluble nanolipoprotein particles. J. Am. Chem. Soc. 131 (2009), 7508–7509.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7508-7509
-
-
Baker, S.1
Hopkins, R.2
Blanchette, C.3
Walsworth, V.4
Sumbad, R.5
Fischer, N.6
Kuhn, E.7
Coleman, M.8
Chromy, B.9
Letant, S.10
Hoeprich, P.11
Adams, M.12
-
7
-
-
77951903021
-
Membrane protein assembly into Nanodiscs
-
Bayburt, T., Sligar, S., Membrane protein assembly into Nanodiscs. FEBS Lett., 2009, 10.1016/j.febslet.2009.10.024.
-
(2009)
FEBS Lett.
-
-
Bayburt, T.1
Sligar, S.2
-
8
-
-
0043007514
-
Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins
-
Bayburt, T.H., Grinkova, Y.V., Sligar, S.G., Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins. Nano Lett. 2 (2002), 853–856.
-
(2002)
Nano Lett.
, vol.2
, pp. 853-856
-
-
Bayburt, T.H.1
Grinkova, Y.V.2
Sligar, S.G.3
-
9
-
-
33744928866
-
Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs
-
Bayburt, T., Grinkova, Y., Sligar, S., Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs. Arch. Biochem. Biophys. 450 (2006), 215–222.
-
(2006)
Arch. Biochem. Biophys.
, vol.450
, pp. 215-222
-
-
Bayburt, T.1
Grinkova, Y.2
Sligar, S.3
-
10
-
-
4444313551
-
tRNA dynamics on the ribosome during translation
-
Blanchard, S., Kim, H., Gonzalez, R., Puglisi, J., Chu, S., tRNA dynamics on the ribosome during translation. Proc. Natl. Acad. Sci. USA 101 (2004), 12893–12898.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12893-12898
-
-
Blanchard, S.1
Kim, H.2
Gonzalez, R.3
Puglisi, J.4
Chu, S.5
-
11
-
-
33746856934
-
Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties
-
Boldog, T., Grimme, S., Li, M., Sligar, S., Hazelbauer, G., Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties. Proc. Natl. Acad. Sci. USA 103 (2006), 11509–11514.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11509-11514
-
-
Boldog, T.1
Grimme, S.2
Li, M.3
Sligar, S.4
Hazelbauer, G.5
-
12
-
-
34250854730
-
Using Nanodiscs to create water-soluble transmembrane chemoreceptors inserted in lipid bilayers
-
Boldog, T., Li, M., Hazelbauer, G., Using Nanodiscs to create water-soluble transmembrane chemoreceptors inserted in lipid bilayers. Methods Enzymol. 423 (2007), 317–335.
-
(2007)
Methods Enzymol.
, vol.423
, pp. 317-335
-
-
Boldog, T.1
Li, M.2
Hazelbauer, G.3
-
13
-
-
33746894560
-
Inter-helix distances in lysophospholipid micelle-bound alpha-synuclein from pulsed ESR measurements
-
Borbat, P., Ramlall, T., Freed, J., Eliezer, D., Inter-helix distances in lysophospholipid micelle-bound alpha-synuclein from pulsed ESR measurements. J. Am. Chem. Soc. 128 (2006), 10004–10005.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 10004-10005
-
-
Borbat, P.1
Ramlall, T.2
Freed, J.3
Eliezer, D.4
-
14
-
-
67650759736
-
Single-molecule studies of the neuronal SNARE fusion machinery
-
Brunger, A., Weninger, K., Bowen, M., Chu, S., Single-molecule studies of the neuronal SNARE fusion machinery. Annu. Rev. Biochem. 78 (2009), 903–928.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 903-928
-
-
Brunger, A.1
Weninger, K.2
Bowen, M.3
Chu, S.4
-
15
-
-
0038054286
-
A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins
-
Bussell, R., Eliezer, D., A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins. J. Mol. Biol. 329 (2003), 763–778.
-
(2003)
J. Mol. Biol.
, vol.329
, pp. 763-778
-
-
Bussell, R.1
Eliezer, D.2
-
16
-
-
0038341134
-
A broken alpha-helix in folded alpha-synuclein
-
Chandra, S., Chen, X., Rizo, J., Jahn, R., Sudhof, T., A broken alpha-helix in folded alpha-synuclein. J. Biol. Chem. 278 (2003), 15313–15318.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15313-15318
-
-
Chandra, S.1
Chen, X.2
Rizo, J.3
Jahn, R.4
Sudhof, T.5
-
17
-
-
22244442489
-
The biochemistry of Parkinson's disease
-
Cookson, M., The biochemistry of Parkinson's disease. Annu. Rev. Biochem. 74 (2005), 29–52.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 29-52
-
-
Cookson, M.1
-
18
-
-
0032540327
-
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
-
Davidson, W., Jonas, A., Clayton, D., George, J., Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J. Biol. Chem. 273 (1998), 9443–9449.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9443-9449
-
-
Davidson, W.1
Jonas, A.2
Clayton, D.3
George, J.4
-
19
-
-
58149199796
-
Allosteric P450 mechanisms: Multiple binding sites, multiple conformers or both?
-
Davydov, D., Halpert, J., Allosteric P450 mechanisms: Multiple binding sites, multiple conformers or both?. Expert Opin. Drug Met. 4 (2008), 1523–1535.
-
(2008)
Expert Opin. Drug Met.
, vol.4
, pp. 1523-1535
-
-
Davydov, D.1
Halpert, J.2
-
20
-
-
27144459868
-
Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: Heterogeneity of the enzyme caused by its oligomerization
-
Davydov, D., Fernando, H., Baas, B., Sligar, S., Halpert, J., Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: Heterogeneity of the enzyme caused by its oligomerization. Biochemistry 44 (2005), 13902–13913.
-
(2005)
Biochemistry
, vol.44
, pp. 13902-13913
-
-
Davydov, D.1
Fernando, H.2
Baas, B.3
Sligar, S.4
Halpert, J.5
-
21
-
-
34347326224
-
Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: Pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket
-
Davydov, D., Baas, B., Sligar, S., Halpert, J., Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: Pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket. Biochemistry 46 (2007), 7852–7864.
-
(2007)
Biochemistry
, vol.46
, pp. 7852-7864
-
-
Davydov, D.1
Baas, B.2
Sligar, S.3
Halpert, J.4
-
22
-
-
1642382983
-
Directed self-assembly of monodisperse phospholipid bilayer nanodiscs with controlled size
-
Denisov, I., Grinkova, Y., Lazarides, A., Sligar, S., Directed self-assembly of monodisperse phospholipid bilayer nanodiscs with controlled size. J. Am. Chem. Soc. 126 (2004), 3477–3487.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 3477-3487
-
-
Denisov, I.1
Grinkova, Y.2
Lazarides, A.3
Sligar, S.4
-
23
-
-
24344483500
-
Thermotropic phase transition in soluble nanoscale lipid bilayers
-
Denisov, I., McLean, M., Shaw, A., Grinkova, Y., Sligar, S., Thermotropic phase transition in soluble nanoscale lipid bilayers. J. Phys. Chem. B 109 (2005), 15580–15588.
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 15580-15588
-
-
Denisov, I.1
McLean, M.2
Shaw, A.3
Grinkova, Y.4
Sligar, S.5
-
24
-
-
34147112191
-
Cooperativity in cytochrome P450 3A4: Linkages in substrate binding, spin state, uncoupling, and product formation
-
Denisov, I., Baas, B., Grinkova, Y., Sligar, S., Cooperativity in cytochrome P450 3A4: Linkages in substrate binding, spin state, uncoupling, and product formation. J. Biol. Chem. 282 (2007), 7066–7076.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7066-7076
-
-
Denisov, I.1
Baas, B.2
Grinkova, Y.3
Sligar, S.4
-
25
-
-
69249241970
-
Cooperative properties of cytochromes P450
-
Denisov, I., Frank, D., Sligar, S., Cooperative properties of cytochromes P450. Pharmacol. Therapeut. 124 (2009), 151–167.
-
(2009)
Pharmacol. Therapeut.
, vol.124
, pp. 151-167
-
-
Denisov, I.1
Frank, D.2
Sligar, S.3
-
26
-
-
9144238054
-
Proton-powered subunit rotation in single membrane-bound F0F1-ATP synthase
-
Diez, M., Zimmermann, B., Borsch, M., Konig, M., Schweinberger, E., Steigmiller, S., Reuter, R., Felekyan, S., Kudryavtsev, V., Seidel, C., Graber, P., Proton-powered subunit rotation in single membrane-bound F0F1-ATP synthase. Nat. Struct. Mol. Biol. 11 (2004), 135–141.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 135-141
-
-
Diez, M.1
Zimmermann, B.2
Borsch, M.3
Konig, M.4
Schweinberger, E.5
Steigmiller, S.6
Reuter, R.7
Felekyan, S.8
Kudryavtsev, V.9
Seidel, C.10
Graber, P.11
-
27
-
-
45749089759
-
Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein
-
Drescher, M., Veldhuis, G., van Rooijen, B., Milikisyants, S., Subramaniam, V., Huber, M., Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein. J. Am. Chem. Soc. 130 (2008), 7796–7797.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 7796-7797
-
-
Drescher, M.1
Veldhuis, G.2
van Rooijen, B.3
Milikisyants, S.4
Subramaniam, V.5
Huber, M.6
-
28
-
-
33947595805
-
Role of subunit interactions in P450 oligomers in the loss of homotropic cooperativity in the cytochrome P450 3A4 mutant L211F/D214E/F304W
-
Fernando, H., Davydov, D., Chin, C., Halpert, J., Role of subunit interactions in P450 oligomers in the loss of homotropic cooperativity in the cytochrome P450 3A4 mutant L211F/D214E/F304W. Arch. Biochem. Biophys. 460 (2007), 129–140.
-
(2007)
Arch. Biochem. Biophys.
, vol.460
, pp. 129-140
-
-
Fernando, H.1
Davydov, D.2
Chin, C.3
Halpert, J.4
-
29
-
-
65249185574
-
Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence
-
Ferreon, A., Gambin, Y., Lemke, E., Deniz, A., Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proc. Natl. Acad. Sci. USA 106 (2009), 5645–5650.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5645-5650
-
-
Ferreon, A.1
Gambin, Y.2
Lemke, E.3
Deniz, A.4
-
30
-
-
33646041015
-
Probing lipid vesicles by bimolecular association and dissociation trajectories of single molecules
-
Gao, F., Mei, E., Lim, M., Hochstrasser, R., Probing lipid vesicles by bimolecular association and dissociation trajectories of single molecules. J. Am. Chem. Soc. 128 (2006), 4814–4822.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 4814-4822
-
-
Gao, F.1
Mei, E.2
Lim, M.3
Hochstrasser, R.4
-
31
-
-
34547133736
-
Single molecule techniques for the study of membrane proteins
-
Garcia-Saez, A., Schwille, P., Single molecule techniques for the study of membrane proteins. Appl. Microbiol. Biotechnol. 76 (2007), 257–266.
-
(2007)
Appl. Microbiol. Biotechnol.
, vol.76
, pp. 257-266
-
-
Garcia-Saez, A.1
Schwille, P.2
-
32
-
-
33751271800
-
Handbook of Single Molecule Fluorescence Spectroscopy
-
Oxford University Press Oxford, NY
-
Gell, C., Brockwell, D., Smith, A., Handbook of Single Molecule Fluorescence Spectroscopy. 2006, Oxford University Press, Oxford, NY.
-
(2006)
-
-
Gell, C.1
Brockwell, D.2
Smith, A.3
-
33
-
-
0029127954
-
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
-
George, J., Jin, H., Woods, W., Clayton, D., Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15 (1995), 361–372.
-
(1995)
Neuron
, vol.15
, pp. 361-372
-
-
George, J.1
Jin, H.2
Woods, W.3
Clayton, D.4
-
34
-
-
58149173445
-
Membrane-bound alpha-synuclein forms an extended helix: Long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles
-
Georgieva, E., Ramlall, T., Borbat, P., Freed, J., Eliezer, D., Membrane-bound alpha-synuclein forms an extended helix: Long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles. J. Am. Chem. Soc. 130 (2008), 12856–12857.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 12856-12857
-
-
Georgieva, E.1
Ramlall, T.2
Borbat, P.3
Freed, J.4
Eliezer, D.5
-
35
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert, M., Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2 (2001), 492–501.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
36
-
-
50049094961
-
Structure and composition of self-assembled discoidal phospholipid bilayer nanoparticles formed with different membrane scaffold proteins
-
Grinkova, Y., Denisov, I., Bayburt, T., Sligar, S., Structure and composition of self-assembled discoidal phospholipid bilayer nanoparticles formed with different membrane scaffold proteins. Biophys. J., 86, 2004, 252A.
-
(2004)
Biophys. J.
, vol.86
, pp. 252A
-
-
Grinkova, Y.1
Denisov, I.2
Bayburt, T.3
Sligar, S.4
-
37
-
-
0034973773
-
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
-
Guengerich, F., Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem. Res. Toxicol. 14 (2001), 611–650.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 611-650
-
-
Guengerich, F.1
-
38
-
-
67650325176
-
The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: Insights from type II diabetes
-
Hebda, J., Miranker, A., The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: Insights from type II diabetes. Annu. Rev. Biophys. 38 (2009), 125–152.
-
(2009)
Annu. Rev. Biophys.
, vol.38
, pp. 125-152
-
-
Hebda, J.1
Miranker, A.2
-
39
-
-
0027976593
-
Deconvolutions based on singular-value decomposition and the pseudoinverse—A guide for beginners
-
Hendler, R., Shrager, R., Deconvolutions based on singular-value decomposition and the pseudoinverse—A guide for beginners. J. Biochem. Biophys. Methods 28 (1994), 1–33.
-
(1994)
J. Biochem. Biophys. Methods
, vol.28
, pp. 1-33
-
-
Hendler, R.1
Shrager, R.2
-
40
-
-
36849048228
-
Intrinsic motions along an enzymatic reaction trajectory
-
Henzler-Wildman, K., Thai, V., Lei, M., Ott, M., Wolf-Watz, M., Fenn, T., Pozharski, E., Wilson, M., Petsko, G., Karplus, M., Hubner, C., Kern, D., Intrinsic motions along an enzymatic reaction trajectory. Nature 450 (2007), 838–844.
-
(2007)
Nature
, vol.450
, pp. 838-844
-
-
Henzler-Wildman, K.1
Thai, V.2
Lei, M.3
Ott, M.4
Wolf-Watz, M.5
Fenn, T.6
Pozharski, E.7
Wilson, M.8
Petsko, G.9
Karplus, M.10
Hubner, C.11
Kern, D.12
-
41
-
-
34250346536
-
Multiple sequential steps involved in the binding of inhibitors to cytochrome p450 3A4
-
Isin, E., Guengerich, F., Multiple sequential steps involved in the binding of inhibitors to cytochrome p450 3A4. J. Biol. Chem. 282 (2007), 6863–6874.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6863-6874
-
-
Isin, E.1
Guengerich, F.2
-
42
-
-
2942555022
-
Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling
-
Jao, C., Der-Sarkissian, A., Chen, J., Langen, R., Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling. Proc. Natl. Acad. Sci. USA 101 (2004), 8331–8336.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8331-8336
-
-
Jao, C.1
Der-Sarkissian, A.2
Chen, J.3
Langen, R.4
-
43
-
-
58149380718
-
Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement
-
Jao, C., Hegde, B., Chen, J., Haworth, I., Langen, R., Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement. Proc. Natl. Acad. Sci. USA 105 (2008), 19666–19671.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19666-19671
-
-
Jao, C.1
Hegde, B.2
Chen, J.3
Haworth, I.4
Langen, R.5
-
44
-
-
0034602296
-
Alpha-synuclein membrane interactions and lipid specificity
-
Jo, E., McLaurin, J., Yip, C., St George-Hyslop, P., Fraser, P., Alpha-synuclein membrane interactions and lipid specificity. J. Biol. Chem. 275 (2000), 34328–34334.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34328-34334
-
-
Jo, E.1
McLaurin, J.2
Yip, C.3
St George-Hyslop, P.4
Fraser, P.5
-
45
-
-
23744500479
-
SciPy: Open Source Scientific Tools for Python
-
Jones, E., Oliphant, T., Peterson, P., SciPy: Open Source Scientific Tools for Python. http://scipy.org, 2001.
-
(2001)
-
-
Jones, E.1
Oliphant, T.2
Peterson, P.3
-
46
-
-
36849083490
-
Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4
-
Kijac, A., Li, Y., Sligar, S., Rienstra, C., Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4. Biochemistry 46 (2007), 13696–13703.
-
(2007)
Biochemistry
, vol.46
, pp. 13696-13703
-
-
Kijac, A.1
Li, Y.2
Sligar, S.3
Rienstra, C.4
-
47
-
-
58849094579
-
Single-molecule fluorescence studies of a PH domain: New insights into the membrane docking reaction
-
Knight, J., Falke, J., Single-molecule fluorescence studies of a PH domain: New insights into the membrane docking reaction. Biophys. J. 96 (2007), 566–582.
-
(2007)
Biophys. J.
, vol.96
, pp. 566-582
-
-
Knight, J.1
Falke, J.2
-
48
-
-
4143094106
-
Phospholipid catalysis of diabetic amyloid assembly
-
Knight, J., Miranker, A., Phospholipid catalysis of diabetic amyloid assembly. J. Mol. Biol. 341 (2004), 1175–1187.
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 1175-1187
-
-
Knight, J.1
Miranker, A.2
-
49
-
-
33747119677
-
Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide
-
Knight, J., Hebda, J., Miranker, A., Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide. Biochemistry 45 (2006), 9496–9508.
-
(2006)
Biochemistry
, vol.45
, pp. 9496-9508
-
-
Knight, J.1
Hebda, J.2
Miranker, A.3
-
50
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
Koshland, D., Nemethy, G., Filmer, D., Comparison of experimental binding data and theoretical models in proteins containing subunits. Biochemistry 5 (1966), 365–385.
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland, D.1
Nemethy, G.2
Filmer, D.3
-
51
-
-
33644897629
-
Dynamic polymorphism of single actin molecules in the actin filament
-
Kozuka, J., Yokota, H., Arai, Y., Ishii, Y., Yanagida, T., Dynamic polymorphism of single actin molecules in the actin filament. Nat. Chem. Biol. 2 (2006), 83–86.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 83-86
-
-
Kozuka, J.1
Yokota, H.2
Arai, Y.3
Ishii, Y.4
Yanagida, T.5
-
52
-
-
70350381113
-
Purification and functional reconstitution of monomeric mu-opioid receptors: Allosteric modulation of agonist binding by Gi2
-
Kuszak, A., Pitchiaya, S., Anand, J., Mosberg, H., Walter, N., Sunahara, R., Purification and functional reconstitution of monomeric mu-opioid receptors: Allosteric modulation of agonist binding by Gi2. J. Biol. Chem. 284 (2009), 26732–26741.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26732-26741
-
-
Kuszak, A.1
Pitchiaya, S.2
Anand, J.3
Mosberg, H.4
Walter, N.5
Sunahara, R.6
-
53
-
-
77953865084
-
Principles of fluorescence spectroscopy
-
Springer New York; Berlin
-
Lakowicz, J.R., Principles of fluorescence spectroscopy. 2006, Springer, New York; Berlin.
-
(2006)
-
-
Lakowicz, J.R.1
-
54
-
-
33749521872
-
Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4
-
Lampe, J., Atkins, W., Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4. Biochemistry 45 (2006), 12204–12215.
-
(2006)
Biochemistry
, vol.45
, pp. 12204-12215
-
-
Lampe, J.1
Atkins, W.2
-
55
-
-
38849187174
-
Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4
-
Lampe, J., Fernandez, C., Nath, A., Atkins, W., Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4. Biochemistry 47 (2008), 509–516.
-
(2008)
Biochemistry
, vol.47
, pp. 509-516
-
-
Lampe, J.1
Fernandez, C.2
Nath, A.3
Atkins, W.4
-
56
-
-
33745511381
-
Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology
-
Leitz, A., Bayburt, T., Barnakov, A., Springer, B., Sligar, S., Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology. Biotechniques 40 (2006), 601–612.
-
(2006)
Biotechniques
, vol.40
, pp. 601-612
-
-
Leitz, A.1
Bayburt, T.2
Barnakov, A.3
Springer, B.4
Sligar, S.5
-
57
-
-
65249173508
-
Two-dimensional infrared spectroscopy provides evidence of an intermediate in the membrane-catalyzed assembly of diabetic amyloid
-
Ling, Y., Strasfeld, D., Shim, S., Raleigh, D., Zanni, M., Two-dimensional infrared spectroscopy provides evidence of an intermediate in the membrane-catalyzed assembly of diabetic amyloid. J. Phys. Chem. B 113 (2009), 2498–2505.
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 2498-2505
-
-
Ling, Y.1
Strasfeld, D.2
Shim, S.3
Raleigh, D.4
Zanni, M.5
-
58
-
-
0036797552
-
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
-
Lotharius, J., Brundin, P., Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. Hum. Mol. Genet. 11 (2002), 2395–2407.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2395-2407
-
-
Lotharius, J.1
Brundin, P.2
-
59
-
-
0032484096
-
Single-molecule enzymatic dynamics
-
Lu, H., Xun, L., Xie, X., Single-molecule enzymatic dynamics. Science 282 (1998), 1877–1882.
-
(1998)
Science
, vol.282
, pp. 1877-1882
-
-
Lu, H.1
Xun, L.2
Xie, X.3
-
60
-
-
35949038838
-
Thermodynamic fluctuations in a reacting system—Measurement by fluorescence correlation spectroscopy
-
Magde, D., Webb, W., Elson, E., Thermodynamic fluctuations in a reacting system—Measurement by fluorescence correlation spectroscopy. Phys. Rev. Lett. 29 (1972), 705–708.
-
(1972)
Phys. Rev. Lett.
, vol.29
, pp. 705-708
-
-
Magde, D.1
Webb, W.2
Elson, E.3
-
61
-
-
60349096360
-
Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol
-
Mishra, R., Sellin, D., Radovan, D., Gohlke, A., Winter, R., Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol. ChemBioChem 10 (2009), 445–449.
-
(2009)
ChemBioChem
, vol.10
, pp. 445-449
-
-
Mishra, R.1
Sellin, D.2
Radovan, D.3
Gohlke, A.4
Winter, R.5
-
62
-
-
78651189765
-
On nature of allosteric transitions—A plausible model
-
Monod, J., Wyman, J., Changeux, J., On nature of allosteric transitions—A plausible model. J. Mol. Biol. 12 (1965), 88–118.
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.3
-
63
-
-
48449100432
-
Blood clotting reactions on nanoscale phospholipid bilayers
-
Morrissey, J., Pureza, V., Davis-Harrison, R., Sligar, S., Ohkubo, Y., Tajkhorshid, E., Blood clotting reactions on nanoscale phospholipid bilayers. Thromb. Res. 122:Suppl 1 (2008), S23–S26.
-
(2008)
Thromb. Res.
, vol.122
, pp. S23-S26
-
-
Morrissey, J.1
Pureza, V.2
Davis-Harrison, R.3
Sligar, S.4
Ohkubo, Y.5
Tajkhorshid, E.6
-
64
-
-
2442538177
-
Single-molecule imaging analysis of Ras activation in living cells
-
Murakoshi, H., Iino, R., Kobayashi, T., Fujiwara, T., Ohshima, C., Yoshimura, A., Kusumi, A., Single-molecule imaging analysis of Ras activation in living cells. Proc. Natl. Acad. Sci. USA 101 (2004), 7317–7322.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7317-7322
-
-
Murakoshi, H.1
Iino, R.2
Kobayashi, T.3
Fujiwara, T.4
Ohshima, C.5
Yoshimura, A.6
Kusumi, A.7
-
65
-
-
57049174009
-
Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy
-
Nanga, R., Brender, J., Xu, J., Veglia, G., Ramamoorthy, A., Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy. Biochemistry 47 (2008), 12689–12697.
-
(2008)
Biochemistry
, vol.47
, pp. 12689-12697
-
-
Nanga, R.1
Brender, J.2
Xu, J.3
Veglia, G.4
Ramamoorthy, A.5
-
66
-
-
33847639732
-
Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins
-
Nath, A., Atkins, W., Sligar, S., Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins. Biochemistry 46 (2007), 2059–2069.
-
(2007)
Biochemistry
, vol.46
, pp. 2059-2069
-
-
Nath, A.1
Atkins, W.2
Sligar, S.3
-
67
-
-
35349009104
-
Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: The effect of model membranes
-
Nath, A., Grinkova, Y., Sligar, S., Atkins, W., Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: The effect of model membranes. J. Biol. Chem. 282 (2007), 28309–28320.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 28309-28320
-
-
Nath, A.1
Grinkova, Y.2
Sligar, S.3
Atkins, W.4
-
68
-
-
43949143494
-
Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4
-
Nath, A., Fernández, C., Lampe, J., Atkins, W., Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4. Arch. Biochem. Biophys. 474 (2008), 198–204.
-
(2008)
Arch. Biochem. Biophys.
, vol.474
, pp. 198-204
-
-
Nath, A.1
Fernández, C.2
Lampe, J.3
Atkins, W.4
-
69
-
-
56749165088
-
Allosteric effects on substrate dissociation from cytochrome P450 3A4 in Nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy
-
Nath, A., Koo, P., Rhoades, E., Atkins, W., Allosteric effects on substrate dissociation from cytochrome P450 3A4 in Nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy. J. Am. Chem. Soc. 130 (2008), 15746–15747.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 15746-15747
-
-
Nath, A.1
Koo, P.2
Rhoades, E.3
Atkins, W.4
-
70
-
-
30444447501
-
Reverse cholesterol transport and cholesterol efflux in atherosclerosis
-
Ohashi, R., Mu, H., Wang, X., Yao, Q., Chen, C., Reverse cholesterol transport and cholesterol efflux in atherosclerosis. QJM—Int. J. Med. 98 (2005), 845–856.
-
(2005)
QJM—Int. J. Med.
, vol.98
, pp. 845-856
-
-
Ohashi, R.1
Mu, H.2
Wang, X.3
Yao, Q.4
Chen, C.5
-
71
-
-
34548359230
-
Single-molecule fluorescence to study molecular motors
-
Park, H., Toprak, E., Selvin, P., Single-molecule fluorescence to study molecular motors. Q. Rev. Biophys. 40 (2007), 87–111.
-
(2007)
Q. Rev. Biophys.
, vol.40
, pp. 87-111
-
-
Park, H.1
Toprak, E.2
Selvin, P.3
-
72
-
-
3342942688
-
Single-molecule fluorescence spectroscopy and microscopy of biomolecular motors
-
Peterman, E., Sosa, H., Moerner, W., Single-molecule fluorescence spectroscopy and microscopy of biomolecular motors. Annu. Rev. Phys. Chem. 55 (2004), 79–96.
-
(2004)
Annu. Rev. Phys. Chem.
, vol.55
, pp. 79-96
-
-
Peterman, E.1
Sosa, H.2
Moerner, W.3
-
73
-
-
58049205423
-
Image sequence denoising via sparse and redundant representations
-
Protter, M., Elad, M., Image sequence denoising via sparse and redundant representations. IEEE Trans. Image Proc. 18 (2009), 27–35.
-
(2009)
IEEE Trans. Image Proc.
, vol.18
, pp. 27-35
-
-
Protter, M.1
Elad, M.2
-
74
-
-
0037452963
-
Watching proteins fold one molecule at a time
-
Rhoades, E., Gussakovsky, E., Haran, G., Watching proteins fold one molecule at a time. Proc. Natl. Acad. Sci. USA 100 (2003), 3197–3202.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3197-3202
-
-
Rhoades, E.1
Gussakovsky, E.2
Haran, G.3
-
75
-
-
33744788870
-
Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy
-
Rhoades, E., Ramlall, T., Webb, W., Eliezer, D., Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy. Biophys. J. 90 (2006), 4692–4700.
-
(2006)
Biophys. J.
, vol.90
, pp. 4692-4700
-
-
Rhoades, E.1
Ramlall, T.2
Webb, W.3
Eliezer, D.4
-
76
-
-
71549142855
-
Chapter 11—Reconstitution of membrane proteins in phospholipid bilayer nanodiscs
-
Ritchie, T., Grinkova, Y., Bayburt, T., Denisov, I., Zolnerciks, J., Atkins, W., Sligar, S., Chapter 11—Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods Enzymol. 464 (2009), 211–231.
-
(2009)
Methods Enzymol.
, vol.464
, pp. 211-231
-
-
Ritchie, T.1
Grinkova, Y.2
Bayburt, T.3
Denisov, I.4
Zolnerciks, J.5
Atkins, W.6
Sligar, S.7
-
77
-
-
34249951075
-
Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4
-
Roberts, A., Atkins, W., Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4. Arch. Biochem. Biophys. 463 (2007), 89–101.
-
(2007)
Arch. Biochem. Biophys.
, vol.463
, pp. 89-101
-
-
Roberts, A.1
Atkins, W.2
-
78
-
-
44449134820
-
A practical guide to single-molecule FRET
-
Roy, R., Hohng, S., Ha, T., A practical guide to single-molecule FRET. Nat. Methods 5 (2008), 507–516.
-
(2008)
Nat. Methods
, vol.5
, pp. 507-516
-
-
Roy, R.1
Hohng, S.2
Ha, T.3
-
79
-
-
34548170559
-
Interaction of high density lipoprotein particles with membranes containing cholesterol
-
Sanchez, S., Tricerri, M., Gratton, E., Interaction of high density lipoprotein particles with membranes containing cholesterol. J. Lipid Res. 48 (2007), 1689–1700.
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1689-1700
-
-
Sanchez, S.1
Tricerri, M.2
Gratton, E.3
-
80
-
-
0033527736
-
A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein
-
Segrest, J., Jones, M., Klon, A., Sheldahl, C., Hellinger, M., De Loof, H., Harvey, S., A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein. J. Biol. Chem. 274 (1999), 31755–31758.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31755-31758
-
-
Segrest, J.1
Jones, M.2
Klon, A.3
Sheldahl, C.4
Hellinger, M.5
De Loof, H.6
Harvey, S.7
-
81
-
-
34250365394
-
The local phospholipid environment modulates the activation of blood clotting
-
Shaw, A., Pureza, V., Sligar, S., Morrissey, J., The local phospholipid environment modulates the activation of blood clotting. J. Biol. Chem. 282 (2007), 6556–6563.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6556-6563
-
-
Shaw, A.1
Pureza, V.2
Sligar, S.3
Morrissey, J.4
-
82
-
-
67650809065
-
CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis
-
(in press)
-
Subramanian, M., Low, M., Locuson, C., Tracy, T., CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis. Drug Metab. Dispos., 2009, 10.1124/dmd.109.026500 (in press).
-
(2009)
Drug Metab. Dispos.
-
-
Subramanian, M.1
Low, M.2
Locuson, C.3
Tracy, T.4
-
83
-
-
0031748173
-
In vitro and in vivo drug interactions involving human CYP3A
-
Thummel, K., Wilkinson, G., In vitro and in vivo drug interactions involving human CYP3A. Annu. Rev. Pharmacol. 38 (1998), 389–430.
-
(1998)
Annu. Rev. Pharmacol.
, vol.38
, pp. 389-430
-
-
Thummel, K.1
Wilkinson, G.2
-
84
-
-
34547348810
-
Measuring conformational dynamics: A new FCS-FRET approach
-
Torres, T., Levitus, M., Measuring conformational dynamics: A new FCS-FRET approach. J. Phys. Chem. B 111 (2007), 7392–7400.
-
(2007)
J. Phys. Chem. B
, vol.111
, pp. 7392-7400
-
-
Torres, T.1
Levitus, M.2
-
85
-
-
64849109238
-
Alpha-synuclein binds large unilamellar vesicles as an extended helix
-
Trexler, A., Rhoades, E., Alpha-synuclein binds large unilamellar vesicles as an extended helix. Biochemistry 48 (2009), 2304–2306.
-
(2009)
Biochemistry
, vol.48
, pp. 2304-2306
-
-
Trexler, A.1
Rhoades, E.2
-
86
-
-
33846135094
-
Mechanism of interactions of alpha-naphthoflavone with cytochrome p450 3A4 explored with an engineered enzyme bearing a fluorescent probe
-
Tsalkova, T., Davydova, N., Halpert, J., Davydov, D., Mechanism of interactions of alpha-naphthoflavone with cytochrome p450 3A4 explored with an engineered enzyme bearing a fluorescent probe. Biochemistry 46 (2007), 106–119.
-
(2007)
Biochemistry
, vol.46
, pp. 106-119
-
-
Tsalkova, T.1
Davydova, N.2
Halpert, J.3
Davydov, D.4
-
87
-
-
0027489773
-
Molecular-cloning of cDNA-encoding an unrecognized component of amyloid in Alzheimer-disease
-
Ueda, K., Fukushima, H., Masliah, E., Xia, Y., Iwai, A., Yoshimoto, M., Otero, D., Kondo, J., Ihara, Y., Saitoh, T., Molecular-cloning of cDNA-encoding an unrecognized component of amyloid in Alzheimer-disease. Proc. Natl. Acad. Sci. USA 90 (1993), 11282–11286.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
88
-
-
34247843089
-
Subunit counting in membrane-bound proteins
-
Ulbrich, M., Isacoff, E., Subunit counting in membrane-bound proteins. Nat. Methods 4 (2007), 319–321.
-
(2007)
Nat. Methods
, vol.4
, pp. 319-321
-
-
Ulbrich, M.1
Isacoff, E.2
-
89
-
-
15744362063
-
Structure and dynamics of micelle-bound human alpha-synuclein
-
Ulmer, T., Bax, A., Cole, N., Nussbaum, R., Structure and dynamics of micelle-bound human alpha-synuclein. J. Biol. Chem. 280 (2005), 9595–9603.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9595-9603
-
-
Ulmer, T.1
Bax, A.2
Cole, N.3
Nussbaum, R.4
-
90
-
-
66249142313
-
Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy
-
Vogelsang, J., Cordes, T., Forthmann, C., Steinhauer, C., Tinnefeld, P., Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy. Proc. Natl. Acad. Sci. USA 106 (2009), 8107–8112.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8107-8112
-
-
Vogelsang, J.1
Cordes, T.2
Forthmann, C.3
Steinhauer, C.4
Tinnefeld, P.5
-
91
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb, P., Zhen, W., Poon, A., Conway, K., Lansbury, P., NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35 (1996), 13709–13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.1
Zhen, W.2
Poon, A.3
Conway, K.4
Lansbury, P.5
-
92
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton, M., Bokoch, M., Rasmussen, S., Huang, B., Zare, R., Kobilka, B., Sunahara, R., A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc. Natl. Acad. Sci. USA 104 (2007), 7682–7687.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.1
Bokoch, M.2
Rasmussen, S.3
Huang, B.4
Zare, R.5
Kobilka, B.6
Sunahara, R.7
-
93
-
-
3442896773
-
Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone
-
Williams, P., Cosme, J., Vinkovic, D., Ward, A., Angove, H., Day, P., Vonrhein, C., Tickle, I., Jhoti, H., Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. Science 305 (2004), 683–686.
-
(2004)
Science
, vol.305
, pp. 683-686
-
-
Williams, P.1
Cosme, J.2
Vinkovic, D.3
Ward, A.4
Angove, H.5
Day, P.6
Vonrhein, C.7
Tickle, I.8
Jhoti, H.9
-
94
-
-
0346025675
-
Pharmacological and therapeutic properties of ritonavir-boosted protease inhibitor therapy in HIV-infected patients
-
Zeldin, R., Petruschke, R., Pharmacological and therapeutic properties of ritonavir-boosted protease inhibitor therapy in HIV-infected patients. J. Antimicrob. Chemoth. 53 (2004), 4–9.
-
(2004)
J. Antimicrob. Chemoth.
, vol.53
, pp. 4-9
-
-
Zeldin, R.1
Petruschke, R.2
|