Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C

Oncology Reports

Volumn 24, Issue 1, 2010, Pages 271-276

  Moon, Dong Oh ^a,b   Kim, Mun Ock ^a   Nam, Taek Jeong ^c   Kim, Se Kwon ^c   Choi, Yung Hyun ^b   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Dong Eui University   (South Korea)

^c Pukyong National University   (South Korea)

Author keywords

ATM; cdc25C; Chk1 2; G2 M phase arrest; Pectenotoxin 2

Indexed keywords

ACTIN; ATM PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN B1; HYDROGEN PEROXIDE; MARINE TOXIN; PECTENOTOXIN 2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ATM PROTEIN, HUMAN; CDC25C PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHEK2 PROTEIN, HUMAN; DNA BINDING PROTEIN; FURAN DERIVATIVE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PYRAN DERIVATIVE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; DOSE RESPONSE; DOWN REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; BREAST TUMOR; CARCINOMA; CELL CYCLE; CELL DIVISION; DRUG EFFECTS; DRUG SCREENING; FEMALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL CULTURE; UPREGULATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA; CDC25 PHOSPHATASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; DNA-BINDING PROTEINS; DRUG EVALUATION, PRECLINICAL; FEMALE; FURANS; G2 PHASE; HUMANS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PYRANS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CHECKPOINT KINASE 2;

EID: 77952970159     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000856     Document Type: Article

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