Pectenotoxin-2 abolishes constitutively activated NF-κB, leading to suppression of NF-κB related gene products and potentiation of apoptosis

Cancer Letters

Volumn 271, Issue 1, 2008, Pages 25-33

  Kim, Mun Ock ^a   Moon, Dong Oh ^b   Heo, Moon Soo ^b   Lee, Jae Dong ^a   Jung, Jee Hyung ^a   Kim, Se Kwon ^c   Choi, Yung Hyun ^d   Kim, Gi Young ^b  

^a Pusan National University   (South Korea)

^b Jeju National University   (South Korea)

^c Pukyong National University   (South Korea)

^d Dong Eui University   (South Korea)

Author keywords

Apoptosis; Nuclear factor kappa B; Pectenotoxin 2

Indexed keywords

ACTIN; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 3 INHIBITOR; CYCLOOXYGENASE 2; GENE PRODUCT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PECTENOTOXIN 2; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P50; PYRROLIDINE DITHIOCARBAMATE; SYNAPTOTAGMIN I; TOXIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL TYPE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DNA BINDING; RNA TRANSLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FURANS; HUMANS; NF-KAPPA B; PYRANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 53049093846     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.05.034     Document Type: Article

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