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Volumn 61, Issue 6, 2010, Pages 537-546

The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice

Author keywords

Cannabinoid; Capsazepine; FAAH; N arachidonoyl serotonin; TRPV1 receptor; URB597

Indexed keywords

ANANDAMIDE; CAPSAZEPINE; CARRAGEENAN; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; FATTY ACID AMIDASE INHIBITOR; N ARACHIDONOYL SEROTONIN; SEROTONIN AGONIST; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1 ANTAGONIST;

EID: 77952885551     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.02.001     Document Type: Article
Times cited : (58)

References (51)
  • 2
    • 0038013681 scopus 로고    scopus 로고
    • Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin
    • Fowler C.J., Tiger G., Lopez-Rodriguez M.L., Viso A., Ortega-Gutierrez S., Ramos J.A. Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin. J Enzyme Inhib Med Chem 2003, 18:225-231.
    • (2003) J Enzyme Inhib Med Chem , vol.18 , pp. 225-231
    • Fowler, C.J.1    Tiger, G.2    Lopez-Rodriguez, M.L.3    Viso, A.4    Ortega-Gutierrez, S.5    Ramos, J.A.6
  • 3
    • 21344438667 scopus 로고    scopus 로고
    • Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels
    • de Lago E., Petrosini S., Valenti M., Morera E., Ortega-Gutierrez S., Fernandez-Ruiz J., et al. Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels. Biochem Pharmacol 2005, 70:446-452.
    • (2005) Biochem Pharmacol , vol.70 , pp. 446-452
    • de Lago, E.1    Petrosini, S.2    Valenti, M.3    Morera, E.4    Ortega-Gutierrez, S.5    Fernandez-Ruiz, J.6
  • 4
    • 27744526709 scopus 로고    scopus 로고
    • Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal grey and rostral ventromedial medulla
    • Suplita R.L., Farthing J.N., Gutierrez T., Hohmann A.G. Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal grey and rostral ventromedial medulla. Neuropharmacology 2005, 49:1201-1209.
    • (2005) Neuropharmacology , vol.49 , pp. 1201-1209
    • Suplita, R.L.1    Farthing, J.N.2    Gutierrez, T.3    Hohmann, A.G.4
  • 5
    • 33645832524 scopus 로고    scopus 로고
    • Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation
    • D'Argenio G., Valenti M., Scaglione G., Cosenza V., Sorrentini I., Di Marzo V. Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. FASEB J 2006, 20:568-570.
    • (2006) FASEB J , vol.20 , pp. 568-570
    • D'Argenio, G.1    Valenti, M.2    Scaglione, G.3    Cosenza, V.4    Sorrentini, I.5    Di Marzo, V.6
  • 7
    • 9444280832 scopus 로고    scopus 로고
    • A new strategy to block tumor growth by inhibiting endocannabinoid inactivation
    • Bifulco M., Laezza C., Valenti M., Ligresti A., Portella G., Di Marzo V. A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. FASEB J 2004, 18:1606-1608.
    • (2004) FASEB J , vol.18 , pp. 1606-1608
    • Bifulco, M.1    Laezza, C.2    Valenti, M.3    Ligresti, A.4    Portella, G.5    Di Marzo, V.6
  • 8
    • 33947319316 scopus 로고    scopus 로고
    • Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors
    • Maione S., De Petrocellis L., de Novellis V., Schiano Moriello A., Petrosino S., Palazzo E., et al. Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol 2007, 150:766-781.
    • (2007) Br J Pharmacol , vol.150 , pp. 766-781
    • Maione, S.1    De Petrocellis, L.2    de Novellis, V.3    Schiano Moriello, A.4    Petrosino, S.5    Palazzo, E.6
  • 9
    • 2442510225 scopus 로고    scopus 로고
    • Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
    • Lichtman A.H., Shelton C.C., Advani T., Cravatt B.F. Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain 2004, 109:319-327.
    • (2004) Pain , vol.109 , pp. 319-327
    • Lichtman, A.H.1    Shelton, C.C.2    Advani, T.3    Cravatt, B.F.4
  • 10
    • 27144431754 scopus 로고    scopus 로고
    • Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possibile involvement of cannabinoid receptors
    • Holt S., Comelli F., Costa B., Fowler C. Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possibile involvement of cannabinoid receptors. Br J Pharmacol 2005, 146:467-476.
    • (2005) Br J Pharmacol , vol.146 , pp. 467-476
    • Holt, S.1    Comelli, F.2    Costa, B.3    Fowler, C.4
  • 12
    • 33845799619 scopus 로고    scopus 로고
    • Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain
    • Jhaveri M.D., Richardson D., Kendall D.A., Barrett D.A., Chapman V. Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain. J Neurosci 2006, 26:13318-13327.
    • (2006) J Neurosci , vol.26 , pp. 13318-13327
    • Jhaveri, M.D.1    Richardson, D.2    Kendall, D.A.3    Barrett, D.A.4    Chapman, V.5
  • 13
    • 0034636441 scopus 로고    scopus 로고
    • Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
    • Davis J.B., Gray J., Gunthorpe M.J., Hatcher J.P., Davey P.T., Overend P., et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 2000, 405:183-187.
    • (2000) Nature , vol.405 , pp. 183-187
    • Davis, J.B.1    Gray, J.2    Gunthorpe, M.J.3    Hatcher, J.P.4    Davey, P.T.5    Overend, P.6
  • 14
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1
  • 15
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K.M., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988, 32:77-88.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.M.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 16
    • 33644766044 scopus 로고    scopus 로고
    • Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive payhways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors
    • Maione S., Bisogno T., de Novellis V., Palazzo E., Cristino L., Valenti M., et al. Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive payhways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. J Pharmacol Exp Ther 2006, 316:969-982.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 969-982
    • Maione, S.1    Bisogno, T.2    de Novellis, V.3    Palazzo, E.4    Cristino, L.5    Valenti, M.6
  • 17
    • 0027501457 scopus 로고
    • Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities
    • Compton D.R., Rice K.C., De Costa B.R., Razdan R.K., Melvin L.S., Johnson M.R., et al. Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities. J Pharmacol Exp Ther 1993, 265:218-226.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 218-226
    • Compton, D.R.1    Rice, K.C.2    De Costa, B.R.3    Razdan, R.K.4    Melvin, L.S.5    Johnson, M.R.6
  • 18
    • 0015445325 scopus 로고
    • The ring test: a quantitative method for assessing the cataleptic effect of cannabis in mice
    • Pertwee R.G. The ring test: a quantitative method for assessing the cataleptic effect of cannabis in mice. Br J Pharmacol 1972, 46:753-763.
    • (1972) Br J Pharmacol , vol.46 , pp. 753-763
    • Pertwee, R.G.1
  • 19
    • 35648973242 scopus 로고    scopus 로고
    • The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation
    • Comelli F., Giagnoni G., Bettoni I., Colleoni M., Costa B. The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation. Br J Pharmacol 2007, 152:787-794.
    • (2007) Br J Pharmacol , vol.152 , pp. 787-794
    • Comelli, F.1    Giagnoni, G.2    Bettoni, I.3    Colleoni, M.4    Costa, B.5
  • 20
    • 0036221971 scopus 로고    scopus 로고
    • CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
    • Clayton N., Marshall F.H., Bountra C., O'Shaughnessy C.T. CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain 2002, 96:253-260.
    • (2002) Pain , vol.96 , pp. 253-260
    • Clayton, N.1    Marshall, F.H.2    Bountra, C.3    O'Shaughnessy, C.T.4
  • 21
    • 67449119913 scopus 로고    scopus 로고
    • The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation
    • Di Marzo V. The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation. Pharmacol Res 2009, 60:77-84.
    • (2009) Pharmacol Res , vol.60 , pp. 77-84
    • Di Marzo, V.1
  • 23
    • 75349085870 scopus 로고    scopus 로고
    • Dynamic regulation of the endocannabinoid system: implications for analgesia
    • Sagar D.V., Gaw A.G., Okine B.N., Woodhams S.G., Wong A., Kendall D.A., et al. Dynamic regulation of the endocannabinoid system: implications for analgesia. Mol Pain 2009, 5:59-71.
    • (2009) Mol Pain , vol.5 , pp. 59-71
    • Sagar, D.V.1    Gaw, A.G.2    Okine, B.N.3    Woodhams, S.G.4    Wong, A.5    Kendall, D.A.6
  • 24
    • 41649118003 scopus 로고    scopus 로고
    • Prostaglandin E2 glycerol ester, and endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity
    • Hu S.S., Bradshaw H.B., Chen J.S., Tan B., Walker J.M. Prostaglandin E2 glycerol ester, and endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity. Br J Pharmacol 2008, 153:1538-1549.
    • (2008) Br J Pharmacol , vol.153 , pp. 1538-1549
    • Hu, S.S.1    Bradshaw, H.B.2    Chen, J.S.3    Tan, B.4    Walker, J.M.5
  • 25
    • 42749089148 scopus 로고    scopus 로고
    • FAAH and anandamide: is 2-AG really the odd one out?
    • Di Marzo V., Maccarrone M. FAAH and anandamide: is 2-AG really the odd one out?. Trends Pharmacol Sci 2008, 29:229-233.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 229-233
    • Di Marzo, V.1    Maccarrone, M.2
  • 26
    • 38649097877 scopus 로고    scopus 로고
    • Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
    • Maccarrone M., Rossi S., Bari M., De Chiara V., Fezza F., Musella A., et al. Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. Nat Neurosci 2008, 11:152-159.
    • (2008) Nat Neurosci , vol.11 , pp. 152-159
    • Maccarrone, M.1    Rossi, S.2    Bari, M.3    De Chiara, V.4    Fezza, F.5    Musella, A.6
  • 28
    • 0035933419 scopus 로고    scopus 로고
    • Role of vanilloid VR1 receptor in thermal allodynia and hyperalgesia in diabetic mice
    • Kamei J., Zushida K., Morita K., Sasaki M., Tanaka S. Role of vanilloid VR1 receptor in thermal allodynia and hyperalgesia in diabetic mice. Eur J Pharmacol 2001, 422:83-86.
    • (2001) Eur J Pharmacol , vol.422 , pp. 83-86
    • Kamei, J.1    Zushida, K.2    Morita, K.3    Sasaki, M.4    Tanaka, S.5
  • 29
    • 0037215646 scopus 로고    scopus 로고
    • The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain
    • Walker K.M., Urban L., Medhurst S.J., Patel S., Panesar M., Fox A.J., et al. The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 2003, 304:56-62.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 56-62
    • Walker, K.M.1    Urban, L.2    Medhurst, S.J.3    Patel, S.4    Panesar, M.5    Fox, A.J.6
  • 30
    • 41749117999 scopus 로고    scopus 로고
    • Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
    • Gavva N.R., Treanor J.S., Garami A., Fang L., Surapaneni S., Akrami A., et al. Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain 2008, 136:202-210.
    • (2008) Pain , vol.136 , pp. 202-210
    • Gavva, N.R.1    Treanor, J.S.2    Garami, A.3    Fang, L.4    Surapaneni, S.5    Akrami, A.6
  • 31
    • 0032101210 scopus 로고    scopus 로고
    • A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like substance
    • Kwak J.Y., Jung J.Y., Hwang S.W., Lee W.T., Oh U. A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like substance. Neuroscience 1998, 86:619-626.
    • (1998) Neuroscience , vol.86 , pp. 619-626
    • Kwak, J.Y.1    Jung, J.Y.2    Hwang, S.W.3    Lee, W.T.4    Oh, U.5
  • 32
    • 33749170660 scopus 로고    scopus 로고
    • Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity
    • Garcia-Martinez C., Fernandez-Carvajal A., Valenzuela B., Gomis A., Van Den Nest W., Ferroni, et al. Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity. J Pain 2006, 7:735-746.
    • (2006) J Pain , vol.7 , pp. 735-746
    • Garcia-Martinez, C.1    Fernandez-Carvajal, A.2    Valenzuela, B.3    Gomis, A.4    Van Den Nest, W.5    Ferroni6
  • 33
    • 45849106100 scopus 로고    scopus 로고
    • Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain
    • Jhaveri M.D., Richardson D., Robinson I., Garle M.J., Patel A., Sun Y., et al. Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. Neuropharmacology 2008, 55:85-93.
    • (2008) Neuropharmacology , vol.55 , pp. 85-93
    • Jhaveri, M.D.1    Richardson, D.2    Robinson, I.3    Garle, M.J.4    Patel, A.5    Sun, Y.6
  • 34
    • 0031779305 scopus 로고    scopus 로고
    • Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
    • Richardson J.D., Kilo S., Hargreaves K.M. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 1998, 75:111-119.
    • (1998) Pain , vol.75 , pp. 111-119
    • Richardson, J.D.1    Kilo, S.2    Hargreaves, K.M.3
  • 35
    • 34247470251 scopus 로고    scopus 로고
    • Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597)
    • Niforatos W., Zhang X.F., Lake M.R., Walter K.A., Neelands T., Holzman T.F., et al. Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597). Mol Pharmacol 2007, 71:1209-1216.
    • (2007) Mol Pharmacol , vol.71 , pp. 1209-1216
    • Niforatos, W.1    Zhang, X.F.2    Lake, M.R.3    Walter, K.A.4    Neelands, T.5    Holzman, T.F.6
  • 36
    • 39449102203 scopus 로고    scopus 로고
    • Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
    • Gunthorpe M.J., Szallasi A. Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms. Curr Pharm Des 2008, 14:32-41.
    • (2008) Curr Pharm Des , vol.14 , pp. 32-41
    • Gunthorpe, M.J.1    Szallasi, A.2
  • 37
    • 0034958490 scopus 로고    scopus 로고
    • Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen
    • Holt S., Nilsson J., Omeir R., Tiger G., Fowler C.J. Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. Br J Pharmacol 2001, 133:513-520.
    • (2001) Br J Pharmacol , vol.133 , pp. 513-520
    • Holt, S.1    Nilsson, J.2    Omeir, R.3    Tiger, G.4    Fowler, C.J.5
  • 38
    • 0035903191 scopus 로고    scopus 로고
    • Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1
    • Olah Z., Karai L., Iadarola M.J. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. J Biol Chem 2001, 276:31163-31170.
    • (2001) J Biol Chem , vol.276 , pp. 31163-31170
    • Olah, Z.1    Karai, L.2    Iadarola, M.J.3
  • 39
    • 35348938494 scopus 로고    scopus 로고
    • Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors
    • Morgese M.G., Cassano T., Cuomo V., Giuffrida A. Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. Exp Neurol 2007, 208:110-119.
    • (2007) Exp Neurol , vol.208 , pp. 110-119
    • Morgese, M.G.1    Cassano, T.2    Cuomo, V.3    Giuffrida, A.4
  • 40
    • 44449151954 scopus 로고    scopus 로고
    • Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex
    • Rubino T., Realini N., Castiglioni C., Guidali C., Viganò D., Marras E., et al. Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. Cereb Cortex 2008, 18:1292-1301.
    • (2008) Cereb Cortex , vol.18 , pp. 1292-1301
    • Rubino, T.1    Realini, N.2    Castiglioni, C.3    Guidali, C.4    Viganò, D.5    Marras, E.6
  • 41
    • 0020647577 scopus 로고
    • Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin
    • Foreman J.C., Jordan C.C., Oehme P., Renner H. Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin. J Physiol 1983, 335:449-465.
    • (1983) J Physiol , vol.335 , pp. 449-465
    • Foreman, J.C.1    Jordan, C.C.2    Oehme, P.3    Renner, H.4
  • 43
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: a molecular gateway to the pain pathway
    • Caterina M.J., Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Ann Rev Neurosci 2001, 24:487-517.
    • (2001) Ann Rev Neurosci , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 44
    • 0037216692 scopus 로고    scopus 로고
    • Activation of epidermal vanilloid receptor-1 induces release of pro-inflammatory mediators in human keratinocytes
    • Southall M.D., Li T., Gharibova L.S., Pei Y., Nicol G.D., Travers J.B. Activation of epidermal vanilloid receptor-1 induces release of pro-inflammatory mediators in human keratinocytes. J Pharmacol Exp Ther 2003, 304:217-222.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 217-222
    • Southall, M.D.1    Li, T.2    Gharibova, L.S.3    Pei, Y.4    Nicol, G.D.5    Travers, J.B.6
  • 45
    • 33746897302 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications
    • Okajima K., Harada N. Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications. Curr Med Chem 2006, 13:2241-2251.
    • (2006) Curr Med Chem , vol.13 , pp. 2241-2251
    • Okajima, K.1    Harada, N.2
  • 46
    • 34848828195 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid-1 mediates heat shock-induced matrix metalloproteinase-1 expression in human keratinocytes
    • Li W.H., Lee Y.M., Kim J.Y., Kang S., Kim S., Kim K.H., et al. Transient receptor potential vanilloid-1 mediates heat shock-induced matrix metalloproteinase-1 expression in human keratinocytes. J Invest Dermatol 2007, 127:2328-2335.
    • (2007) J Invest Dermatol , vol.127 , pp. 2328-2335
    • Li, W.H.1    Lee, Y.M.2    Kim, J.Y.3    Kang, S.4    Kim, S.5    Kim, K.H.6
  • 47
    • 15744378565 scopus 로고    scopus 로고
    • Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase
    • Tsuboi K., Sun Y.X., Okamoto Y., Araki N., Tonai T., Ueda N. Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase. J Biol Chem 2005, 280:11082-11092.
    • (2005) J Biol Chem , vol.280 , pp. 11082-11092
    • Tsuboi, K.1    Sun, Y.X.2    Okamoto, Y.3    Araki, N.4    Tonai, T.5    Ueda, N.6
  • 48
    • 26444525004 scopus 로고    scopus 로고
    • Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages
    • Sun Y.X., Tsuboi K., Zhao L.Y., Okamoto Y., Lambert D.M., Ueda N. Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages. Biochim Biophys Acta 2005, 1736:211-220.
    • (2005) Biochim Biophys Acta , vol.1736 , pp. 211-220
    • Sun, Y.X.1    Tsuboi, K.2    Zhao, L.Y.3    Okamoto, Y.4    Lambert, D.M.5    Ueda, N.6
  • 49
    • 1642547042 scopus 로고    scopus 로고
    • Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry
    • Weber A., Ni J., Ling K.H., Acheampong A., Tang-Liu D.D., Burk R., et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. J Lipid Res 2004, 45:757-763.
    • (2004) J Lipid Res , vol.45 , pp. 757-763
    • Weber, A.1    Ni, J.2    Ling, K.H.3    Acheampong, A.4    Tang-Liu, D.D.5    Burk, R.6
  • 50
    • 37349099085 scopus 로고    scopus 로고
    • New N-arachidonoylserotonin analogues with potential " dual" mechanism of action against pain
    • Ortar G., Cascio M.G., De Petrocellis L., Morera E., Rossi F., Schiano-Moriello A., et al. New N-arachidonoylserotonin analogues with potential " dual" mechanism of action against pain. J Med Chem 2007, 50:6554-6569.
    • (2007) J Med Chem , vol.50 , pp. 6554-6569
    • Ortar, G.1    Cascio, M.G.2    De Petrocellis, L.3    Morera, E.4    Rossi, F.5    Schiano-Moriello, A.6
  • 51
    • 54049133600 scopus 로고    scopus 로고
    • The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats
    • De Novellis V., Palazzo E., Rossi F., De Petrocellis L., Petrosino S., Giuda F., et al. The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats. Neuropharmacology 2008, 55:1105-1113.
    • (2008) Neuropharmacology , vol.55 , pp. 1105-1113
    • De Novellis, V.1    Palazzo, E.2    Rossi, F.3    De Petrocellis, L.4    Petrosino, S.5    Giuda, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.