Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 3, 2003, Pages 225-231

  Fowler, Christopher J ^a   Tiger, Gunnar ^a   López Rodríguez, María L ^b   Viso, Alma ^b   Ortega Gutiérrez, Silvia ^b   Ramos, José A ^b  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Anandamide; Arachidonoyl serotonin; Cannabinoid receptors; Fatty acid amidohydrolase

Indexed keywords

AMIDE; ANANDAMIDE; CANNABINOID; ENZYME INHIBITOR; ESTER; FATTY ACID AMIDASE; N (3 FURYLMETHYL)ARACHIDONAMIDE; N (FUR 3 YLMETHYL)OLEAMIDE; SEROTONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; BINDING SITES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; ENZYME INHIBITORS; HYDROLYSIS; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, CHEMICAL; POLYUNSATURATED ALKAMIDES; RATS; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; SEROTONIN;

ANIMALIA;

EID: 0038013681     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636031000080216     Document Type: Article

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