Assay format as a cSuccess factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening

Molecules

Volumn 15, Issue 5, 2010, Pages 3010-3037

  Chung, Thomas D Y ^a   Sergienko, Eduard ^a   Millán, José Luis ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Absorption spectroscopy; Alkaline phosphatase; CDP star ; molecular libraries; Chemical library; Diethanolamine (DEA); High throughput screening; Luminescence; Para nitrophenylphosphate; Tissue nonspecific alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE; ENZYME INHIBITOR; ISOENZYME;

CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; HUMAN; METHODOLOGY; MOLECULAR LIBRARY; REVIEW;

ALKALINE PHOSPHATASE; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; ISOENZYMES; SMALL MOLECULE LIBRARIES;

EID: 77952861563     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15053010     Document Type: Review

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