Enzyme replacement therapy for murine hypophosphatasia

Journal of Bone and Mineral Research

Volumn 23, Issue 6, 2008, Pages 777-787

  Millán, José Luis ^a   Narisawa, Sonoko ^a   Lemire, Isabelle ^b   Loisel, Thomas P ^b   Boileau, Guy ^c   Leonard, Pierre ^b   Gramatikova, Svetlana ^a   Terkeltaub, Robert ^d   Camacho, Nancy Pleshko ^e   McKee, Marc D ^f   Crine, Philippe ^b   Whyte, Michael P ^g  

^a BURNHAM INSTITUTE   (United States)

^b Enobia Pharma   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e HOSPITAL FOR SPECIAL SURGERY   (United States)

^f MCGILL UNIVERSITY   (Canada)

^g WASHINGTON UNIVERSITY   (United States)

Author keywords

Alkaline phosphatase; Calcification; Epilepsy; Osteomalacia; Rickets

Indexed keywords

ALKALINE PHOSPHATASE; ASPARTIC ACID; CALCIUM; HYDROXYAPATITE; IMMUNOGLOBULIN G; MINERAL; PYRIDOXAL; PYRIDOXAL 5 PHOSPHATE; PYRIDOXINE; PYROPHOSPHATE; PYROPHOSPHATE INHIBITOR; RECOMBINANT ENZYME; RECOMBINANT TISSUE NONSPECIFIC ALKALINE PHOSPHATASE;

AKP2 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BIOENGINEERING; BONE DISEASE; BONE MINERALIZATION; CALCIFICATION; CALCIUM BLOOD LEVEL; CARBOXY TERMINAL SEQUENCE; CLINICAL FEATURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG MEGADOSE; DRUG PURIFICATION; ENZYME ACTIVITY; ENZYME REPLACEMENT; EPILEPSY; GENE; GENE MUTATION; GROWTH RATE; HYPERCALCEMIA; HYPOPHOSPHATASIA; INBORN ERROR OF METABOLISM; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NEWBORN; NONHUMAN; OSTEOMALACIA; RADIOGRAPHY; RICKETS; SEIZURE; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; SURVIVAL RATE; TISSUE DISTRIBUTION; TNALP GENE; TOOTH DISEASE;

ALKALINE PHOSPHATASE; ANIMALS; BIOLOGICAL THERAPY; HUMANS; HYPOPHOSPHATASIA; MICE; MICE, KNOCKOUT; TIME FACTORS;

EID: 44449145465     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.071213     Document Type: Article

References (53)

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