Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery

Biomaterials

Volumn 28, Issue 3, 2007, Pages 540-549

  Chan, Peggy ^a   Kurisawa, Motoichi ^a   Chung, Joo Eun ^a   Yang, Yi Yan ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

Chitosan; Folate conjugation; Folate receptor targeting; Gene delivery; PEGylation; Water solubility

Indexed keywords

CHITOSAN; FOLATE CONJUGATION; FOLATE RECEPTOR TARGETING; GEL ELECTROPHORESIS; GENE DELIVERY; PEGYLATION; WATER SOLUBILITY;

DNA; GENETIC ENGINEERING; REGRESSION ANALYSIS; SYNTHESIS (CHEMICAL); TUMORS;

ORGANIC COMPOUNDS;

CHITOSAN G POLY(ETHYLENE GLYCOL) FOLATE; FOLIC ACID DERIVATIVE; PLASMID DNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; EMBRYO; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONVIRAL GENE DELIVERY SYSTEM; PH; PRIORITY JOURNAL; REGRESSION ANALYSIS; SOLUBILITY; TUMOR CELL;

CARRIER PROTEINS; CHITOSAN; DNA; DRUG CARRIERS; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; NEOPLASMS; PLASMIDS; POLYETHYLENE GLYCOLS; RECEPTORS, CELL SURFACE; SOLUBILITY; WATER;

EID: 33750185394     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.08.046     Document Type: Article

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