Francisella tularensis ΔpyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo

Infection and Immunity

Volumn 78, Issue 6, 2010, Pages 2607-2619

  Horzempa, Joseph ^a   O'Dee, Dawn M ^a   Shanks, Robert M Q ^a   Nau, Gerard J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN PYRF; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL INVASION; CELL MUTANT; CELL STRAIN HEK293; CONTROLLED STUDY; FEMALE; FIBROBLAST; FRANCISELLA TULARENSIS; HOST CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CHICK EMBRYO; CHICKEN; DISEASE MODEL; EPITHELIUM CELL; GENE DELETION; GENETICS; LUNG; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; TULAREMIA;

ANIMALS; BACTERIAL PROTEINS; CELL LINE; CELLS, CULTURED; CHICK EMBRYO; CHICKENS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; FRANCISELLA TULARENSIS; GENE DELETION; HUMANS; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; TULAREMIA; VIRULENCE FACTORS;

EID: 77952691205     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00134-10     Document Type: Article

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