-
1
-
-
0031747997
-
The role of receptor kinases and arrestins in G protein-coupled receptor regulation
-
Krupnick, J. G. and Benovic, J. L. (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu. Rev. Pharmacol. Toxicol. 38, 289-319
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 289-319
-
-
Krupnick, J.G.1
Benovic, J.L.2
-
2
-
-
0026730336
-
β-Arrestin2, a novel member of the arrestin/β-arrestin gene family
-
Attramadal, H., Arriza, J. L., Aoki, C., Dawson, T. M., Codina, J., Kwatra, M. M., Snyder, S. H., Caron, M. G. and Lefkowitz, R. J. (1992) β-Arrestin2, a novel member of the arrestin/β-arrestin gene family. J. Biol. Chem. 267, 17882-17890
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17882-17890
-
-
Attramadal, H.1
Arriza, J.L.2
Aoki, C.3
Dawson, T.M.4
Codina, J.5
Kwatra, M.M.6
Snyder, S.H.7
Caron, M.G.8
Lefkowitz, R.J.9
-
3
-
-
0025054097
-
2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase
-
2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. Br. J. Clin. Pharmacol. 30, (Suppl. 1), 3S-12S
-
(1990)
Br. J. Clin. Pharmacol.
, vol.30
, Issue.SUPPL. 1
-
-
Benovic, J.L.1
Onorato, J.2
Lohse, M.J.3
Dohlman, H.G.4
Staniszewski, C.5
Caron, M.G.6
Lefkowitz, R.J.7
-
4
-
-
33646414189
-
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
-
Gurevich, V. V. and Gurevich, E. V. (2006) The structural basis of arrestin-mediated regulation of G-protein-coupled receptors. Pharmacol. Ther. 110, 465-502
-
(2006)
Pharmacol. Ther.
, vol.110
, pp. 465-502
-
-
Gurevich, V.V.1
Gurevich, E.V.2
-
5
-
-
0030460743
-
G-protein-coupled receptor regulation: Role of G-protein-coupled receptor kinases and arrestins
-
Ferguson, S. S., Barak, L. S., Zhang, J. and Caron, M. G. (1996) G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Can. J. Physiol. Pharmacol. 74, 1095-1110
-
(1996)
Can. J. Physiol. Pharmacol.
, vol.74
, pp. 1095-1110
-
-
Ferguson, S.S.1
Barak, L.S.2
Zhang, J.3
Caron, M.G.4
-
7
-
-
0027404263
-
β-Adrenergic receptor sequestration: A potential mechanism of receptor resensitization
-
Yu, S. S., Lefkowitz, R. J. and Hausdorff, W. P. (1993) β-Adrenergic receptor sequestration: a potential mechanism of receptor resensitization. J. Biol. Chem. 268, 337-341
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 337-341
-
-
Yu, S.S.1
Lefkowitz, R.J.2
Hausdorff, W.P.3
-
8
-
-
0022885986
-
Phosphorylation/dephosphorylation of the β-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution
-
Sibley, D. R., Strasser, R. H., Benovic, J. L., Daniel, K. and Lefkowitz, R. J. (1986) Phosphorylation/dephosphorylation of the β-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. Proc. Natl. Acad. Sci. U.S.A. 83, 9408-9412
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 9408-9412
-
-
Sibley, D.R.1
Strasser, R.H.2
Benovic, J.L.3
Daniel, K.4
Lefkowitz, R.J.5
-
10
-
-
32244438409
-
355, 356
-
355, 356. Br. J. Pharmacol. 147, 249-259
-
(2006)
Br. J. Pharmacol.
, vol.147
, pp. 249-259
-
-
Iyer, V.1
Tran, T.M.2
Foster, E.3
Dai, W.4
Clark, R.B.5
Knoll, B.J.6
-
11
-
-
0029160524
-
The G-protein-coupled receptor phosphatase: A protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity
-
Pitcher, J. A., Payne, E. S., Csortos, C., DePaoli-Roach, A. A. and Lefkowitz, R. J. (1995) The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proc. Natl. Acad. Sci. U.S.A. 92, 8343-8347
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 8343-8347
-
-
Pitcher, J.A.1
Payne, E.S.2
Csortos, C.3
DePaoli-Roach, A.A.4
Lefkowitz, R.J.5
-
12
-
-
0034595860
-
Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors
-
Oakley, R. H., Laporte, S. A., Holt, J. A., Caron, M. G. and Barak, L. S. (2000) Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J. Biol. Chem. 275, 17201-17210
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Caron, M.G.4
Barak, L.S.5
-
13
-
-
0033527663
-
Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
-
Oakley, R. H., Laporte, S. A., Holt, J. A., Barak, L. S. and Caron, M. G. (1999) Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J. Biol. Chem. 274, 32248-32257
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32248-32257
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Barak, L.S.4
Caron, M.G.5
-
14
-
-
34250351916
-
Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies
-
Jones, B. W., Song, G. J., Greuber, E. K. and Hinkle, P. M. (2007) Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies. J. Biol. Chem. 282, 12893-12906
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12893-12906
-
-
Jones, B.W.1
Song, G.J.2
Greuber, E.K.3
Hinkle, P.M.4
-
15
-
-
32244432344
-
β-Arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor
-
Jones, B. W. and Hinkle, P. M. (2005) β-Arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor. J. Biol. Chem. 280, 38346-38354
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38346-38354
-
-
Jones, B.W.1
Hinkle, P.M.2
-
16
-
-
0037008771
-
Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation
-
Zhu, C. C., Cook, L. B. and Hinkle, P. M. (2002) Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation. J. Biol. Chem. 277, 28228-28237
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28228-28237
-
-
Zhu, C.C.1
Cook, L.B.2
Hinkle, P.M.3
-
17
-
-
74549177146
-
Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase
-
Gehret, A. U., Jones, B. W., Tran, P. N., Cook, L. B., Greuber, E. K. and Hinkle, P. M. (2009) Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase. Mol. Pharmacol. 77, 288-297
-
(2009)
Mol. Pharmacol.
, vol.77
, pp. 288-297
-
-
Gehret, A.U.1
Jones, B.W.2
Tran, P.N.3
Cook, L.B.4
Greuber, E.K.5
Hinkle, P.M.6
-
18
-
-
0022203120
-
Evidence for tight coupling of thyrotropin -releasing hormone receptors to stimulated inositol trisphosphate formation in rat pituitary cells
-
Imai, A. and Gershengorn, M. C. (1985) Evidence for tight coupling of thyrotropin -releasing hormone receptors to stimulated inositol trisphosphate formation in rat pituitary cells. J. Biol. Chem. 260, 10536-10540
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 10536-10540
-
-
Imai, A.1
Gershengorn, M.C.2
-
19
-
-
45749126997
-
Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences
-
Jones, B. W. and Hinkle, P. M. (2008) Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences. Mol. Pharmacol. 74, 195-202
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 195-202
-
-
Jones, B.W.1
Hinkle, P.M.2
-
20
-
-
34547793553
-
A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts
-
Chepurny, O. G. and Holz, G. G. (2007) A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts. J. Biomol. Screen. 12, 740-746
-
(2007)
J. Biomol. Screen.
, vol.12
, pp. 740-746
-
-
Chepurny, O.G.1
Holz, G.G.2
-
21
-
-
0032496280
-
Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics
-
Heding, A., Vrecl, M., Bogerd, J., McGregor, A., Sellar, R., Taylor, P. L. and Eidne, K. A. (1998) Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics. J. Biol. Chem. 273, 11472-11477
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11472-11477
-
-
Heding, A.1
Vrecl, M.2
Bogerd, J.3
McGregor, A.4
Sellar, R.5
Taylor, P.L.6
Eidne, K.A.7
-
23
-
-
0023897940
-
2-adrenergic receptor delays onset of agonist-promoted desensitization
-
2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature 333, 370-373
-
(1988)
Nature
, vol.333
, pp. 370-373
-
-
Bouvier, M.1
Hausdorff, W.P.2
De Blasi, A.3
O'Dowd, B.F.4
Kobilka, B.K.5
Caron, M.G.6
Lefkowitz, R.J.7
-
25
-
-
17644390240
-
Mass spectrometric analysis of agonist effects on posttranslational modifications of the β-2 adrenoceptor in mammalian cells
-
Trester-Zedlitz, M., Burlingame, A., Kobilka, B. and von Zastrow, M. (2005) Mass spectrometric analysis of agonist effects on posttranslational modifications of the β-2 adrenoceptor in mammalian cells. Biochemistry 44, 6133-6143
-
(2005)
Biochemistry
, vol.44
, pp. 6133-6143
-
-
Trester-Zedlitz, M.1
Burlingame, A.2
Kobilka, B.3
Von Zastrow, M.4
-
26
-
-
0033789017
-
2-adrenergic receptor by the GRK pathway
-
2-adrenergic receptor by the GRK pathway. Mol. Pharmacol. 58, 1162-1173
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1162-1173
-
-
Seibold, A.1
Williams, B.2
Huang, Z.F.3
Friedman, J.4
Moore, R.H.5
Knoll, B.J.6
Clark, R.B.7
-
28
-
-
0030664060
-
Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity
-
Gurevich, V. V., Pals-Rylaarsdam, R., Benovic, J. L., Hosey, M. M. and Onorato, J. J. (1997) Agonist-receptor - arrestin, an alternative ternary complex with high agonist affinity. J. Biol. Chem. 272, 28849-28852
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28849-28852
-
-
Gurevich, V.V.1
Pals-Rylaarsdam, R.2
Benovic, J.L.3
Hosey, M.M.4
Onorato, J.J.5
-
30
-
-
37249040944
-
2-adrenergic receptor in plasma membranes by intrinsic GRK5
-
2-adrenergic receptor in plasma membranes by intrinsic GRK5. Biochemistry 46, 14438-14449
-
(2007)
Biochemistry
, vol.46
, pp. 14438-14449
-
-
Tran, T.M.1
Jorgensen, R.2
Clark, R.B.3
-
31
-
-
0029635377
-
Phosphorylation and activation of β-adrenergic receptor kinase by protein kinase C
-
Chuang, T. T., LeVine, 3rd, H. and De Blasi, A. (1995) Phosphorylation and activation of β-adrenergic receptor kinase by protein kinase C. J. Biol. Chem. 270, 18660-18665
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18660-18665
-
-
Chuang, T.T.1
LeVine III, H.2
De Blasi, A.3
-
32
-
-
0029877815
-
Protein kinase cross-talk: Membrane targeting of the β-adrenergic receptor kinase by protein kinase C
-
Winstel, R., Freund, S., Krasel, C., Hoppe, E. and Lohse, M. J. (1996) Protein kinase cross-talk: membrane targeting of the β-adrenergic receptor kinase by protein kinase C. Proc. Natl. Acad. Sci. U.S.A. 93, 2105-2109
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 2105-2109
-
-
Winstel, R.1
Freund, S.2
Krasel, C.3
Hoppe, E.4
Lohse, M.J.5
-
33
-
-
0025820391
-
Mechanism of rhodopsin kinase activation
-
Palczewski, K., Buczyłko, J., Kaplan, M. W., Polans, A. S. and Crabb, J. W. (1991) Mechanism of rhodopsin kinase activation. J. Biol. Chem. 266, 12949-12955
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12949-12955
-
-
Palczewski, K.1
Buczyłko, J.2
Kaplan, M.W.3
Polans, A.S.4
Crabb, J.W.5
-
34
-
-
0028900858
-
Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt
-
Shi, W., Osawa, S., Dickerson, C. D. and Weiss, E. R. (1995) Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt. J. Biol. Chem. 270, 2112-2119
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2112-2119
-
-
Shi, W.1
Osawa, S.2
Dickerson, C.D.3
Weiss, E.R.4
-
35
-
-
0037799206
-
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gβγ
-
Lodowski, D. T., Pitcher, J. A., Capel, W. D., Lefkowitz, R. J. and Tesmer, J. J. (2003) Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gβγ. Science 300, 1256-1262
-
(2003)
Science
, vol.300
, pp. 1256-1262
-
-
Lodowski, D.T.1
Pitcher, J.A.2
Capel, W.D.3
Lefkowitz, R.J.4
Tesmer, J.J.5
-
36
-
-
28844463975
-
Snapshot of activated G proteins at the membrane: The Gαq-GRK2-Gβγ complex
-
Tesmer, V. M., Kawano, T., Shankaranarayanan, A., Kozasa, T. and Tesmer, J. J. (2005) Snapshot of activated G proteins at the membrane: the Gαq-GRK2-Gβγ complex. Science 310, 1686-1690
-
(2005)
Science
, vol.310
, pp. 1686-1690
-
-
Tesmer, V.M.1
Kawano, T.2
Shankaranarayanan, A.3
Kozasa, T.4
Tesmer, J.J.5
-
37
-
-
46649109793
-
Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation
-
Singh, P., Wang, B., Maeda, T., Palczewski, K. and Tesmer, J. J. (2008) Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation. J. Biol. Chem. 283, 14053-14062
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14053-14062
-
-
Singh, P.1
Wang, B.2
Maeda, T.3
Palczewski, K.4
Tesmer, J.J.5
-
38
-
-
0030593035
-
Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
Ferguson, S. S., Downey, 3rd, W. E., Colapietro, A. M., Barak, L. S., Menard, L. and Caron, M. G. (1996) Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271, 363-366
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.1
Downey III, W.E.2
Colapietro, A.M.3
Barak, L.S.4
Menard, L.5
Caron, M.G.6
-
40
-
-
0030863054
-
Internalization of the m2 muscarinic acetylcholine receptor: Arrestin-independent and -dependent pathways
-
Pals-Rylaarsdam, R., Gurevich, V. V., Lee, K. B., Ptasienski, J. A., Benovic, J. L. and Hosey, M. M. (1997) Internalization of the m2 muscarinic acetylcholine receptor: arrestin-independent and -dependent pathways. J. Biol. Chem. 272, 23682-23689
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23682-23689
-
-
Pals-Rylaarsdam, R.1
Gurevich, V.V.2
Lee, K.B.3
Ptasienski, J.A.4
Benovic, J.L.5
Hosey, M.M.6
-
41
-
-
0033638108
-
Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites
-
Mendez, A., Burns, M. E., Roca, A., Lem, J., Wu, L. W., Simon, M. I., Baylor, D. A. and Chen, J. (2000) Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron 28, 153-164
-
(2000)
Neuron
, vol.28
, pp. 153-164
-
-
Mendez, A.1
Burns, M.E.2
Roca, A.3
Lem, J.4
Wu, L.W.5
Simon, M.I.6
Baylor, D.A.7
Chen, J.8
-
42
-
-
36148992935
-
Regulation of arrestin binding by rhodopsin phosphorylation level
-
Vishnivetskiy, S. A., Raman, D., Wei, J., Kennedy, M. J., Hurley, J. B. and Gurevich, V. V. (2007) Regulation of arrestin binding by rhodopsin phosphorylation level. J. Biol. Chem. 282, 32075-32083
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32075-32083
-
-
Vishnivetskiy, S.A.1
Raman, D.2
Wei, J.3
Kennedy, M.J.4
Hurley, J.B.5
Gurevich, V.V.6
-
43
-
-
55849100391
-
2-adrenergic receptor by mutation of the C-terminal lysines: Effects on ubiquitination, intracellular trafficking, and degradation
-
2-adrenergic receptor by mutation of the C-terminal lysines: effects on ubiquitination, intracellular trafficking, and degradation. Biochemistry 47, 11750-11762
-
(2008)
Biochemistry
, vol.47
, pp. 11750-11762
-
-
Liang, W.1
Hoang, Q.2
Clark, R.B.3
Fishman, P.H.4
-
44
-
-
0030613761
-
2-adrenergic receptor to different G proteins by protein kinase A
-
2-adrenergic receptor to different G proteins by protein kinase A. Nature 390, 88-91
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
45
-
-
0034611757
-
2-adrenergic receptor complex facilitates receptor phosphorylation and signaling
-
2-adrenergic receptor complex facilitates receptor phosphorylation and signaling. Curr. Biol. 10, 409-412
-
(2000)
Curr. Biol.
, vol.10
, pp. 409-412
-
-
Fraser, I.D.1
Cong, M.2
Kim, J.3
Rollins, E.N.4
Daaka, Y.5
Lefkowitz, R.J.6
Scott, J.D.7
-
46
-
-
0032986997
-
Pharmacological inhibition of protein kinases in intact cells: Antagonism of β adrenergic receptor ligand binding by H-89 reveals limitations of usefulness
-
Penn, R. B., Parent, J. L., Pronin, A. N., Panettieri, Jr, R. A. and Benovic, J. L. (1999) Pharmacological inhibition of protein kinases in intact cells: antagonism of β adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. J. Pharmacol. Exp. Ther. 288, 428-437
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.288
, pp. 428-437
-
-
Penn, R.B.1
Parent, J.L.2
Pronin, A.N.3
Panettieri Jr., R.A.4
Benovic, J.L.5
|