Accelerated dephosphorylation of the β2-adrenergic receptor by mutation of the C-terminal lysines: Effects on ubiquitination, intracellular trafficking, and degradation

Biochemistry

Volumn 47, Issue 45, 2008, Pages 11750-11762

  Liang, Wei ^a   Hoang, Quang ^a   Clark, Richard B ^b   Fishman, Peter H ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINO ACIDS; ANIMAL CELL CULTURE; ARGON; ASSAYS; CELLS; CHEMICAL REACTIONS; CYTOLOGY; DEGRADATION; PHOSPHORYLATION; PORT TERMINALS; RECYCLING;

ADRENERGIC RECEPTORS; COUPLED RECEPTORS; DEPHOSPHORYLATION; G PROTEINS; IN CELLS; INTRACELLULAR TRAFFICKING; OKADAIC ACIDS; PHOSPHATASE INHIBITORS; PLASMA MEMBRANES; RECEPTOR ENDOCYTOSISES; RECEPTOR TRAFFICKING; STIMULATED CELLS; TRANSLATIONAL MODIFICATIONS; UBIQUITINATION; WHOLE CELLS;

CELL MEMBRANES;

ARGININE DERIVATIVE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; LYSINE DERIVATIVE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; LYSINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FREE SYSTEM; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; GENE MUTATION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LYSOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; UBIQUITINATION; WILD TYPE; CELL LINE; CHEMISTRY; CONFOCAL MICROSCOPY; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

CELL LINE; HUMANS; LYSINE; MICROSCOPY, CONFOCAL; MUTATION; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 55849100391     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800219q     Document Type: Article

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