The effect of focal adhesion kinase gene silencing on 5-fluorouracil chemosensitivity involves an Akt/NF-κB signaling pathway in colorectal carcinomas

International Journal of Cancer

Volumn 127, Issue 1, 2010, Pages 195-206

  Chen, Yuying ^a,b   Wang, Zhanxiang ^c   Chang, Pingan ^b   Xiang, Liuxin ^b   Pan, Feng ^a   Li, Jianjun ^a   Jiang, Jinyan ^a   Zou, Lan ^a   Yang, Li ^a   Bian, Zhiheng ^a   Liang, Houjie ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Chemosensitivity; Colorectal carcinoma; Focal adhesion kinase; Multicellular resistance; Multicellular spheroids

Indexed keywords

FLUOROURACIL; FOCAL ADHESION KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B; SHORT HAIRPIN RNA; ANTINEOPLASTIC ANTIMETABOLITE; PRIMER DNA;

ADULT; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL DIFFERENTIATION; CHEMOSENSITIVITY; COLON CARCINOMA; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IC 50; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTICELLULAR SPHEROID; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; AGED; COLORECTAL TUMOR; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA PRIMERS; FEMALE; FLUOROURACIL; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 77952525651     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25025     Document Type: Article

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