Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal

Stem Cells

Volumn 28, Issue 5, 2010, Pages 874-884

  Yoon, Byung Sun ^a   Jun, Eun Kyoung ^a   Park, Gyuman ^b   Yoo, Seung Jun ^a   Moon, Jai Hee ^a   Baik, Cheong Soon ^c   Kim, Aeree ^b   Kim, Hyunggee ^a   Kim, Jong Hoon ^a   Koh, Gou Young ^d   Lee, Hoon Taek ^e   You, Seungkwon ^a  

^a Korea University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Samkwang Medical Laboratories   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^e Konkuk University   (South Korea)

Author keywords

Human embryonic stem cells; Okadaic acid; Protein phosphatase 2A; Self renewal; Xeno free

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BASIC FIBROBLAST GROWTH FACTOR; GREEN FLUORESCENT PROTEIN; MYC PROTEIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; TELOMERASE; C2 CERAMIDE; CERAMIDE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL RENEWAL; CONTROLLED STUDY; DRUG INHIBITION; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL PROLIFERATION; CULTURE MEDIUM; EMBRYO; ENZYME REPRESSION; GENE OVEREXPRESSION; GERM LAYER; IN VITRO STUDY; IN VIVO STUDY; KARYOTYPE;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CULTURE MEDIA, CONDITIONED; DOWN-REGULATION; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; OKADAIC ACID; PLURIPOTENT STEM CELLS; PROTEIN PHOSPHATASE 2; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 77952396835     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.412     Document Type: Article

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