Conformational consequences of ionization of Lys, Asp, and glu buried at position 66 in staphylococcal nuclease

Biochemistry

Volumn 49, Issue 19, 2010, Pages 4138-4146

  Bertrand Garcia Moreno E ^a   Karp, Daniel A ^a   Stahley, Mary R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-BASE TITRATION; APPARENT DIELECTRIC CONSTANT; CD SPECTROSCOPY; FREE ENERGY LANDSCAPE; GLOBAL STABILITY; HIGH DIELECTRIC CONSTANTS; IONIZABLE GROUPS; MICROENVIRONMENTS; STABLE FORM; STAPHYLOCOCCAL NUCLEASE; STATIC STRUCTURES; STRUCTURAL REORGANIZATION; STRUCTURE-BASED; TRP-FLUORESCENCE; UV- AND;

IONIZATION OF LIQUIDS; PARTICLE DETECTORS; PERMITTIVITY; TITRATION;

PROTEINS;

ASPARAGINE; GLUTAMIC ACID; LYSINE; TRYPTOPHAN;

ACCURACY; AMINO ACID SEQUENCE; ARTICLE; DIELECTRIC CONSTANT; FLUORESCENCE ANALYSIS; IONIZATION; NONHUMAN; PKA; PRIORITY JOURNAL; PROTEIN STABILITY; SPECTROSCOPY; STAPHYLOCOCCAL NUCLEASE; STAPHYLOCOCCUS; ULTRAVIOLET RADIATION;

ASPARTIC ACID; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; KINETICS; LYSINE; MICROCOCCAL NUCLEASE; MODELS, MOLECULAR; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 77952354807     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902114m     Document Type: Article

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