Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding

FEBS Journal

Volumn 272, Issue 15, 2005, Pages 3960-3966

  Su, Zhengding ^c   Wu, Jiun Ming ^a   Fang, Huey Jen ^a   Tsong, Tian Yow ^b,c   Chen, Hueih Min ^a  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b INSTITUTE OF PHYSICS   (Taiwan)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Aromatic amino acid; Refolding; Stability; Staphylococcal nuclease

Indexed keywords

ALANINE; BACTERIAL ENZYME; LYSINE; NUCLEASE; STAPHYLOCOCCAL NUCLEASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DENATURATION; DIFFERENTIAL SCANNING CALORIMETRY; ENTHALPY; ENZYME STABILITY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMOSTABILITY;

CIRCULAR DICHROISM; ENZYME STABILITY; LYSINE; MICROCOCCAL NUCLEASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN RENATURATION; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; TRYPTOPHAN;

EID: 23644462394     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04814.x     Document Type: Article

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