-
2
-
-
31344461659
-
Innate immune recognition of viral infection
-
Kawai, T.; Akira, S. Innate immune recognition of viral infection. Nat. Immunol. 2006, 7, 131-137.
-
(2006)
Nat. Immunol
, vol.7
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
3
-
-
0023159806
-
Interferons and their actions
-
Pestka, S.; Langer, J.A.; Zoon, K.C.; Samuel, C.E. Interferons and their actions. Annu. Rev. Biochem. 1987, 56, 727-777.
-
(1987)
Annu. Rev. Biochem
, vol.56
, pp. 727-777
-
-
Pestka, S.1
Langer, J.A.2
Zoon, K.C.3
Samuel, C.E.4
-
4
-
-
9644262469
-
Interferons, interferon-like cytokines, and their receptors
-
Pestka, S.; Krause, C.D.; Walter, M.R. Interferons, interferon-like cytokines, and their receptors. Immunol. Rev. 2004, 202, 8-32.
-
(2004)
Immunol. Rev
, vol.202
, pp. 8-32
-
-
Pestka, S.1
Krause, C.D.2
Walter, M.R.3
-
5
-
-
0036715591
-
Viruses and interferon: A fight for supremacy
-
Katze, M.G.; He, Y.; Gale, M. Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2002, 2, 675-687.
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 675-687
-
-
Katze, M.G.1
He, Y.2
Gale, M.3
-
6
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J.E.; Kerr, I.M.; Stark, G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264, 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
7
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
Platanias, L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 2005, 5, 375-386.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
8
-
-
31144463847
-
Cytokines as critical co-stimulatory molecules in modulating the immune response of natural killer cells
-
Young, H.A.; Ortaldo, J. Cytokines as critical co-stimulatory molecules in modulating the immune response of natural killer cells. Cell Res. 2006, 16, 20-24.
-
(2006)
Cell Res
, vol.16
, pp. 20-24
-
-
Young, H.A.1
Ortaldo, J.2
-
9
-
-
36749069393
-
Interferons at age 50: Past, current and future impact on biomedicine
-
Borden, E.C.; Sen, G.C.; Uze, G.; Silverman, R.H.; Ransohoff, R.M.; Foster, G.R.; Stark, G.R. Interferons at age 50: Past, current and future impact on biomedicine. Nat. Rev. Drug Discov. 2007, 6, 975-990.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 975-990
-
-
Borden, E.C.1
Sen, G.C.2
Uze, G.3
Silverman, R.H.4
Ransohoff, R.M.5
Foster, G.R.6
Stark, G.R.7
-
10
-
-
34547099363
-
The interferons: 50 years after their discovery, there is much more to learn
-
Pestka, S. The interferons: 50 years after their discovery, there is much more to learn. J. Biol. Chem. 2007, 282, 20047-20051.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20047-20051
-
-
Pestka, S.1
-
11
-
-
0038792224
-
Map kinase signaling pathways and hematologic malignancies
-
Platanias, L.C. Map kinase signaling pathways and hematologic malignancies. Blood 2003, 101, 4667-4679.
-
(2003)
Blood
, vol.101
, pp. 4667-4679
-
-
Platanias, L.C.1
-
12
-
-
0344304443
-
Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1
-
Nusinzon, I.; Horvath, C.M. Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1. Proc. Natl. Acad. Sci. USA 2003, 100, 14742-14747.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14742-14747
-
-
Nusinzon, I.1
Horvath, C.M.2
-
13
-
-
0035958901
-
The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells
-
Mayer, I.A.; Verma, A.; Grumbach, I.M.; Uddin, S.; Lekmine, F.; Ravandi, F.; Majchrzak, B.; Fujita, S.; Fish, E.N.; Platanias, L.C. The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells. J. Biol. Chem. 2001, 276, 28570-28577.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 28570-28577
-
-
Mayer, I.A.1
Verma, A.2
Grumbach, I.M.3
Uddin, S.4
Lekmine, F.5
Ravandi, F.6
Majchrzak, B.7
Fujita, S.8
Fish, E.N.9
Platanias, L.C.10
-
14
-
-
0742322159
-
Interferons: Mechanisms of action and clinical applications
-
Parmar, S.; Platanias, L.C. Interferons: Mechanisms of action and clinical applications. Curr. Opin. Oncol. 2003, 15, 431-439.
-
(2003)
Curr. Opin. Oncol
, vol.15
, pp. 431-439
-
-
Parmar, S.1
Platanias, L.C.2
-
15
-
-
0037204953
-
A road map for those who don't know JAK-STAT
-
Aaronson, D.S.; Horvath, C.M. A road map for those who don't know JAK-STAT. Science 2002, 296, 1653-1655.
-
(2002)
Science
, vol.296
, pp. 1653-1655
-
-
Aaronson, D.S.1
Horvath, C.M.2
-
16
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn, G.P.; Bruce, A.T.; Ikeda, H.; Old, L.J.; Schreiber, R.D. Cancer immunoediting: From immunosurveillance to tumor escape. Nat. Immunol. 2002, 3, 991-998.
-
(2002)
Nat. Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
17
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran, V.; Ikeda, H.; Bruce, A.T.; White, J.M.; Swanson, P.E.; Old, L.J.; Schreiber, R.D., IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001, 410, 1107-1111.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
Schreiber, R.D.7
-
18
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
Kaplan, D.H.; Shankaran, V.; Dighe, A.S.; Stockert, E.; Aguet, M.; Old, L.J.; Schreiber, R.D. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc. Natl. Acad. Sci. USA 1998, 95, 7556-7561.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
Stockert, E.4
Aguet, M.5
Old, L.J.6
Schreiber, R.D.7
-
19
-
-
34547097764
-
The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: Implication for the defective interferon response in cancer cells
-
Noser, J.A.; Mael, A.A.; Sakuma, R.; Ohmine, S.; Marcato, P.; Lee, P.W.; Ikeda, Y. The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: Implication for the defective interferon response in cancer cells. Mol. Ther. 2007, 15, 1531-1536.
-
(2007)
Mol. Ther
, vol.15
, pp. 1531-1536
-
-
Noser, J.A.1
Mael, A.A.2
Sakuma, R.3
Ohmine, S.4
Marcato, P.5
Lee, P.W.6
Ikeda, Y.7
-
20
-
-
10744222975
-
Jak1 deficiency leads to enhanced Abelsoninduced B-cell tumor formation
-
Sexl, V.; Kovacic, B.; Piekorz, R.; Moriggl, R.; Stoiber, D.; Hoffmeyer, A.; Liebminger, R.; Kudlacek, O.; Weisz, E.; Rothammer, K.; Ihle, J.N. Jak1 deficiency leads to enhanced Abelsoninduced B-cell tumor formation. Blood 2003, 101, 4937-4943.
-
(2003)
Blood
, vol.101
, pp. 4937-4943
-
-
Sexl, V.1
Kovacic, B.2
Piekorz, R.3
Moriggl, R.4
Stoiber, D.5
Hoffmeyer, A.6
Liebminger, R.7
Kudlacek, O.8
Weisz, E.9
Rothammer, K.10
Ihle, J.N.11
-
21
-
-
62849127652
-
Critical role for constitutive type I interferon signaling in the prevention of cellular transformation
-
Chen, H.M.; Tanaka, N.; Mitani, Y.; Oda, E.; Nozawa, H.; Chen, J.Z.; Yanai, H.; Negishi, H.; Choi, M.K.; Iwasaki, T.; Yamamoto, H.; Taniguchi, T.; Takaoka, A. Critical role for constitutive type I interferon signaling in the prevention of cellular transformation. Cancer Sci. 2009, 100, 449-456.
-
(2009)
Cancer Sci
, vol.100
, pp. 449-456
-
-
Chen, H.M.1
Tanaka, N.2
Mitani, Y.3
Oda, E.4
Nozawa, H.5
Chen, J.Z.6
Yanai, H.7
Negishi, H.8
Choi, M.K.9
Iwasaki, T.10
Yamamoto, H.11
Taniguchi, T.12
Takaoka, A.13
-
22
-
-
2542441665
-
The BCR-ABL story: Bench to bedside and back
-
Wong, S.; Witte, O.N. The BCR-ABL story: Bench to bedside and back. Annu. Rev. Immunol. 2004, 22, 247-306.
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 247-306
-
-
Wong, S.1
Witte, O.N.2
-
23
-
-
16844383633
-
Altered IFNgamma signaling and preserved susceptibility to activated natural killer cell-mediated lysis of BCR/ABL targets
-
Cebo, C.; Voutsadakis, I.A.; Da Rocha, S.; Bourhis, J.H.; Jalil, A.; Azzarone, B.; Turhan, A.G.; Chelbi-Alix, M.; Chouaib, S.; Caignard, A. Altered IFNgamma signaling and preserved susceptibility to activated natural killer cell-mediated lysis of BCR/ABL targets. Cancer Res. 2005, 65, 2914-2920.
-
(2005)
Cancer Res
, vol.65
, pp. 2914-2920
-
-
Cebo, C.1
Voutsadakis, I.A.2
da Rocha, S.3
Bourhis, J.H.4
Jalil, A.5
Azzarone, B.6
Turhan, A.G.7
Chelbi-Alix, M.8
Chouaib, S.9
Caignard, A.10
-
24
-
-
0033973215
-
Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha
-
Pansky, A.; Hildebrand, P.; Fasler-Kan, E.; Baselgia, L.; Ketterer, S.; Beglinger, C.; Heim, M.H. Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha. Int. J. Cancer 2000, 85, 720-725.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 720-725
-
-
Pansky, A.1
Hildebrand, P.2
Fasler-Kan, E.3
Baselgia, L.4
Ketterer, S.5
Beglinger, C.6
Heim, M.H.7
-
25
-
-
52949089050
-
JAKs in pathology: Role of Janus kinases in hematopoietic malignancies and immunodeficiencies
-
Vainchenker, W.; Dusa, A.; Constantinescu, S.N. JAKs in pathology: Role of Janus kinases in hematopoietic malignancies and immunodeficiencies. Semin. Cell Dev. Biol. 2008, 19, 385-393.
-
(2008)
Semin. Cell Dev. Biol
, vol.19
, pp. 385-393
-
-
Vainchenker, W.1
Dusa, A.2
Constantinescu, S.N.3
-
26
-
-
34248583886
-
MAP kinase signalling pathways in cancer
-
Dhillon, A.S.; Hagan, S.; Rath, O.; Kolch, W. MAP kinase signalling pathways in cancer. Oncogene 2007, 26, 3279-3290.
-
(2007)
Oncogene
, vol.26
, pp. 3279-3290
-
-
Dhillon, A.S.1
Hagan, S.2
Rath, O.3
Kolch, W.4
-
27
-
-
67049158197
-
Impaired interferon signaling is a common immune defect in human cancer
-
Critchley-Thorne, R.J.; Simons, D.L.; Yan, N.; Miyahira, A.K.; Dirbas, F.M.; Johnson, D.L.; Swetter, S.M.; Carlson, R.W.; Fisher, G.A.; Koong, A.; Holmes, S.; Lee, P.P. Impaired interferon signaling is a common immune defect in human cancer. Proc. Natl. Acad. Sci. USA 2009, 106, 9010-9015.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9010-9015
-
-
Critchley-Thorne, R.J.1
Simons, D.L.2
Yan, N.3
Miyahira, A.K.4
Dirbas, F.M.5
Johnson, D.L.6
Swetter, S.M.7
Carlson, R.W.8
Fisher, G.A.9
Koong, A.10
Holmes, S.11
Lee, P.P.12
-
28
-
-
61849126356
-
Human interferon-lambda3 is a potent member of the type III interferon family
-
Dellgren, C.; Gad, H.H.; Hamming, O.J.; Melchjorsen, J.; Hartmann, R. Human interferon-lambda3 is a potent member of the type III interferon family. Genes Immun. 2009, 10, 125-131.
-
(2009)
Genes Immun
, vol.10
, pp. 125-131
-
-
Dellgren, C.1
Gad, H.H.2
Hamming, O.J.3
Melchjorsen, J.4
Hartmann, R.5
-
29
-
-
0020490017
-
Structure and expression of human IFN-alpha genes
-
Weissmann, C.; Nagata, S.; Boll, W.; Fountoulakis, M.; Fujisawa, A.; Fujisawa, J.I.; Haynes, J.; Henco, K.; Mantei, N.; Ragg, H.; Schein, C.; Schmid, J.; Shaw, G.; Streuli, M.; Taira, H.; Todokoro, K.; Weidle, U. Structure and expression of human IFN-alpha genes. Philos. Trans. R. Soc. Lond. B Biol. Sci. 1982, 299, 7-28.
-
(1982)
Philos. Trans. R. Soc. Lond. B Biol. Sci
, vol.299
, pp. 7-28
-
-
Weissmann, C.1
Nagata, S.2
Boll, W.3
Fountoulakis, M.4
Fujisawa, A.5
Fujisawa, J.I.6
Haynes, J.7
Henco, K.8
Mantei, N.9
Ragg, H.10
Schein, C.11
Schmid, J.12
Shaw, G.13
Streuli, M.14
Taira, H.15
Todokoro, K.16
Weidle, U.17
-
30
-
-
0025376590
-
The regulation of beta-interferon gene expression
-
Goodbourn, S. The regulation of beta-interferon gene expression. Semin. Cancer Biol. 1990, 1, 89-95.
-
(1990)
Semin. Cancer Biol
, vol.1
, pp. 89-95
-
-
Goodbourn, S.1
-
31
-
-
0023506134
-
Multiple interferon subtypes: The phenomenon and its relevance
-
Rubinstein, M. Multiple interferon subtypes: The phenomenon and its relevance. J. Interferon Res. 1987, 7, 545-551.
-
(1987)
J. Interferon Res
, vol.7
, pp. 545-551
-
-
Rubinstein, M.1
-
32
-
-
0035858379
-
Improvements in protein PEGylation: Pegylated interferons for treatment of hepatitis C
-
Kozlowski, A.; Harris, J.M. Improvements in protein PEGylation: Pegylated interferons for treatment of hepatitis C. J. Control Release 2001, 72, 217-224.
-
(2001)
J. Control Release
, vol.72
, pp. 217-224
-
-
Kozlowski, A.1
Harris, J.M.2
-
33
-
-
51549092094
-
The impact of PEGylation on biological therapies
-
Veronese, F.M.; Mero, A. The impact of PEGylation on biological therapies. BioDrugs 2008, 22, 315-329.
-
(2008)
BioDrugs
, vol.22
, pp. 315-329
-
-
Veronese, F.M.1
Mero, A.2
-
34
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea, J.J.; Gadina, M.; Schreiber, R.D. Cytokine signaling in 2002: New surprises in the Jak/Stat pathway. Cell 2002, 109, 121-131.
-
(2002)
Cell
, vol.109
, pp. 121-131
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
35
-
-
34547116656
-
Type I interferon receptors: Biochemistry and biological functions
-
de Weerd, N.A.; Samarajiwa, S.A.; Hertzog, P.J. Type I interferon receptors: Biochemistry and biological functions. J. Biol. Chem. 2007, 282, 20053-20057.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20053-20057
-
-
de Weerd, N.A.1
Samarajiwa, S.A.2
Hertzog, P.J.3
-
36
-
-
0031424937
-
The interferon gamma (IFN-gamma) receptor: A paradigm for the multichain cytokine receptor
-
Pestka, S.; Kotenko, S.V.; Muthukumaran, G.; Izotova, L.S.; Cook, J.R.; Garotta, G. The interferon gamma (IFN-gamma) receptor: A paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 1997, 8, 189-206.
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 189-206
-
-
Pestka, S.1
Kotenko, S.V.2
Muthukumaran, G.3
Izotova, L.S.4
Cook, J.R.5
Garotta, G.6
-
37
-
-
0030889207
-
The IFN gamma receptor: A paradigm for cytokine receptor signaling
-
Bach, E.A.; Aguet, M.; Schreiber, R.D. The IFN gamma receptor: A paradigm for cytokine receptor signaling. Annu. Rev. Immunol. 1997, 15, 563-591.
-
(1997)
Annu. Rev. Immunol
, vol.15
, pp. 563-591
-
-
Bach, E.A.1
Aguet, M.2
Schreiber, R.D.3
-
38
-
-
0037243222
-
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
-
Kotenko, S.V.; Gallagher, G.; Baurin, V.V.; Lewis-Antes, A.; Shen, M.; Shah, N.K.; Langer, J.A.; Sheikh, F.; Dickensheets, H.; Donnelly, R.P. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 2003, 4, 69-77.
-
(2003)
Nat. Immunol
, vol.4
, pp. 69-77
-
-
Kotenko, S.V.1
Gallagher, G.2
Baurin, V.V.3
Lewis-Antes, A.4
Shen, M.5
Shah, N.K.6
Langer, J.A.7
Sheikh, F.8
Dickensheets, H.9
Donnelly, R.P.10
-
39
-
-
0037236826
-
IL-28, IL-29 and their class II cytokine receptor IL-28R
-
Sheppard, P.; Kindsvogel, W.; Xu, W.; Henderson, K.; Schlutsmeyer, S.; Whitmore, T.E.; Kuestner, R.; Garrigues, U.; Birks, C.; Roraback, J.; Ostrander, C.; Dong, D.; Shin, J.; Presnell, S.; Fox, B.; Haldeman, B.; Cooper, E.; Taft, D.; Gilbert, T.; Grant, F.J.; Tackett, M.; Krivan, W.; McKnight, G.; Clegg, C.; Foster, D.; Klucher, K.M. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat. Immunol. 2003, 4, 63-68.
-
(2003)
Nat. Immunol
, vol.4
, pp. 63-68
-
-
Sheppard, P.1
Kindsvogel, W.2
Xu, W.3
Henderson, K.4
Schlutsmeyer, S.5
Whitmore, T.E.6
Kuestner, R.7
Garrigues, U.8
Birks, C.9
Roraback, J.10
Ostrander, C.11
Dong, D.12
Shin, J.13
Presnell, S.14
Fox, B.15
Haldeman, B.16
Cooper, E.17
Taft, D.18
Gilbert, T.19
Grant, F.J.20
Tackett, M.21
Krivan, W.22
McKnight, G.23
Clegg, C.24
Foster, D.25
Klucher, K.M.26
more..
-
40
-
-
34147161091
-
Viral infections activate types I and III interferon genes through a common mechanism
-
Onoguchi, K.; Yoneyama, M.; Takemura, A.; Akira, S.; Taniguchi, T.; Namiki, H.; Fujita, T. Viral infections activate types I and III interferon genes through a common mechanism. J. Biol. Chem. 2007, 282, 7576-7581.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 7576-7581
-
-
Onoguchi, K.1
Yoneyama, M.2
Takemura, A.3
Akira, S.4
Taniguchi, T.5
Namiki, H.6
Fujita, T.7
-
41
-
-
34447273319
-
Type III interferon(IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases
-
Zhou, Z.; Hamming, O.J.; Ank, N.; Paludan, S.R.; Nielsen, A.L.; Hartmann, R. Type III interferon(IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases. J. Virol. 2007, 81, 7749-7758.
-
(2007)
J. Virol
, vol.81
, pp. 7749-7758
-
-
Zhou, Z.1
Hamming, O.J.2
Ank, N.3
Paludan, S.R.4
Nielsen, A.L.5
Hartmann, R.6
-
42
-
-
0032754656
-
Serum levels of soluble interferon Alfa/Beta receptor as an inhibitory factor of interferon in the patients with chronic hepatitis C
-
Mizukoshi, E.; Kaneko, S.; Kaji, K.; Terasaki, S.; Matsushita, E.; Muraguchi, M.; Ohmoto, Y.; Kobayashi, K. Serum levels of soluble interferon Alfa/Beta receptor as an inhibitory factor of interferon in the patients with chronic hepatitis C. Hepatology 1999, 30, 1325-1331.
-
(1999)
Hepatology
, vol.30
, pp. 1325-1331
-
-
Mizukoshi, E.1
Kaneko, S.2
Kaji, K.3
Terasaki, S.4
Matsushita, E.5
Muraguchi, M.6
Ohmoto, Y.7
Kobayashi, K.8
-
43
-
-
33745134040
-
Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence
-
Frodsham, A.J.; Zhang, L.; Dumpis, U.; Taib, N.A.; Best, S.; Durham, A.; Hennig, B.J.; Hellier, S.; Knapp, S.; Wright, M.; Chiaramonte, M.; Bell, J.I.; Graves, M.; Whittle, H.C.; Thomas, H.C.; Thursz, M.R.; Hill, A.V. Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence. Proc. Natl. Acad. Sci. USA 2006, 103, 9148-9153.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9148-9153
-
-
Frodsham, A.J.1
Zhang, L.2
Dumpis, U.3
Taib, N.A.4
Best, S.5
Durham, A.6
Hennig, B.J.7
Hellier, S.8
Knapp, S.9
Wright, M.10
Chiaramonte, M.11
Bell, J.I.12
Graves, M.13
Whittle, H.C.14
Thomas, H.C.15
Thursz, M.R.16
Hill, A.V.17
-
44
-
-
21044457219
-
IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response
-
Leyva, L.; Fernandez, O.; Fedetz, M.; Blanco, E.; Fernandez, V.E.; Oliver, B.; Leon, A.; Pinto- Medel, M.J.; Mayorga, C.; Guerrero, M.; Luque, G.; Alcina, A.; Matesanz, F. IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response. J. Neuroimmunol. 2005, 163, 165-171.
-
(2005)
J. Neuroimmunol
, vol.163
, pp. 165-171
-
-
Leyva, L.1
Fernandez, O.2
Fedetz, M.3
Blanco, E.4
Fernandez, V.E.5
Oliver, B.6
Leon, A.7
Pinto-Medel, M.J.8
Mayorga, C.9
Guerrero, M.10
Luque, G.11
Alcina, A.12
Matesanz, F.13
-
45
-
-
0035863894
-
The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties
-
Hardy, M.P.; Owczarek, C.M.; Trajanovska, S.; Liu, X.; Kola, I.; Hertzog, P.J. The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties. Blood 2001, 97, 473-482.
-
(2001)
Blood
, vol.97
, pp. 473-482
-
-
Hardy, M.P.1
Owczarek, C.M.2
Trajanovska, S.3
Liu, X.4
Kola, I.5
Hertzog, P.J.6
-
46
-
-
0142105396
-
SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor
-
Kumar, K.G.; Tang, W.; Ravindranath, A.K.; Clark, W.A.; Croze, E.; Fuchs, S.Y. SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor. EMBO J. 2003, 22, 5480-5490.
-
(2003)
EMBO J
, vol.22
, pp. 5480-5490
-
-
Kumar, K.G.1
Tang, W.2
Ravindranath, A.K.3
Clark, W.A.4
Croze, E.5
Fuchs, S.Y.6
-
47
-
-
22144465860
-
A critical function for type I interferons in cancer immunoediting
-
Dunn, G.P.; Bruce, A.T.; Sheehan, K.C.; Shankaran, V.; Uppaluri, R.; Bui, J.D.; Diamond, M.S.; Koebel, C.M.; Arthur, C.; White, J.M.; Schreiber, R.D. A critical function for type I interferons in cancer immunoediting. Nat. Immunol. 2005, 6, 722-729.
-
(2005)
Nat. Immunol
, vol.6
, pp. 722-729
-
-
Dunn, G.P.1
Bruce, A.T.2
Sheehan, K.C.3
Shankaran, V.4
Uppaluri, R.5
Bui, J.D.6
Diamond, M.S.7
Koebel, C.M.8
Arthur, C.9
White, J.M.10
Schreiber, R.D.11
-
48
-
-
0033128466
-
Expression of type I interferon receptor in renal cell carcinoma
-
Morell-Quadreny, L.; Fenollosa-Entrena, B.; Clar-Blanch, F.; Navarro-Fos, S.; Llombart-Bosch, A. Expression of type I interferon receptor in renal cell carcinoma. Oncol. Rep. 1999, 6, 639-642.
-
(1999)
Oncol. Rep
, vol.6
, pp. 639-642
-
-
Morell-Quadreny, L.1
Fenollosa-Entrena, B.2
Clar-Blanch, F.3
Navarro-Fos, S.4
Llombart-Bosch, A.5
-
49
-
-
42449165060
-
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
-
Steelman, L.S.; Abrams, S.L.; Whelan, J.; Bertrand, F.E.; Ludwig, D.E.; Basecke, J.; Libra, M.; Stivala, F.; Milella, M.; Tafuri, A.; Lunghi, P.; Bonati, A.; Martelli, A.M.; McCubrey, J.A. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 2008, 22, 686-707.
-
(2008)
Leukemia
, vol.22
, pp. 686-707
-
-
Steelman, L.S.1
Abrams, S.L.2
Whelan, J.3
Bertrand, F.E.4
Ludwig, D.E.5
Basecke, J.6
Libra, M.7
Stivala, F.8
Milella, M.9
Tafuri, A.10
Lunghi, P.11
Bonati, A.12
Martelli, A.M.13
McCubrey, J.A.14
-
50
-
-
41849116690
-
Roles of unphosphorylated STATs in signaling
-
Yang, J.; Stark, G.R. Roles of unphosphorylated STATs in signaling. Cell Res. 2008, 18, 443-451.
-
(2008)
Cell Res
, vol.18
, pp. 443-451
-
-
Yang, J.1
Stark, G.R.2
-
51
-
-
36849082588
-
Non-conventional signal transduction by type 1 interferons: The NF-kappaB pathway
-
Du, Z.; Wei, L.; Murti, A.; Pfeffer, S.R.; Fan, M.; Yang, C.H.; Pfeffer, L.M. Non-conventional signal transduction by type 1 interferons: The NF-kappaB pathway. J. Cell Biochem. 2007, 102, 1087-1094.
-
(2007)
J. Cell Biochem
, vol.102
, pp. 1087-1094
-
-
Du, Z.1
Wei, L.2
Murti, A.3
Pfeffer, S.R.4
Fan, M.5
Yang, C.H.6
Pfeffer, L.M.7
-
52
-
-
0026632288
-
A protein tyrosine kinase in the interferon alpha/beta signaling pathway
-
Velazquez, L.; Fellous, M.; Stark, G.R.; Pellegrini, S. A protein tyrosine kinase in the interferon alpha/beta signaling pathway. Cell 1992, 70, 313-322.
-
(1992)
Cell
, vol.70
, pp. 313-322
-
-
Velazquez, L.1
Fellous, M.2
Stark, G.R.3
Pellegrini, S.4
-
53
-
-
0035823201
-
A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130
-
Hilkens, C.M.; Is'harc, H.; Lillemeier, B.F.; Strobl, B.; Bates, P.A.; Behrmann, I.; Kerr, I.M. A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130. FEBS Lett. 2001, 505, 87-91.
-
(2001)
FEBS Lett
, vol.505
, pp. 87-91
-
-
Hilkens, C.M.1
Is'harc, H.2
Lillemeier, B.F.3
Strobl, B.4
Bates, P.A.5
Behrmann, I.6
Kerr, I.M.7
-
54
-
-
18244393495
-
Unexpected effects of FERM domain mutations on catalytic activity of Jak3: Structural implication for Janus kinases
-
Zhou, Y.J.; Chen, M.; Cusack, N.A.; Kimmel, L.H.; Magnuson, K.S.; Boyd, J.G.; Lin, W.; Roberts, J.L.; Lengi, A.; Buckley, R.H.; Geahlen, R.L.; Candotti, F.; Gadina, M.; Changelian, P.S.; O'Shea, J.J. Unexpected effects of FERM domain mutations on catalytic activity of Jak3: Structural implication for Janus kinases. Mol. Cell 2001, 8, 959-969.
-
(2001)
Mol. Cell
, vol.8
, pp. 959-969
-
-
Zhou, Y.J.1
Chen, M.2
Cusack, N.A.3
Kimmel, L.H.4
Magnuson, K.S.5
Boyd, J.G.6
Lin, W.7
Roberts, J.L.8
Lengi, A.9
Buckley, R.H.10
Geahlen, R.L.11
Candotti, F.12
Gadina, M.13
Changelian, P.S.14
O'Shea, J.J.15
-
55
-
-
0033696404
-
Partial impairment of cytokine responses in Tyk2-deficient mice
-
Karaghiosoff, M.; Neubauer, H.; Lassnig, C.; Kovarik, P.; Schindler, H.; Pircher, H.; McCoy, B.; Bogdan, C.; Decker, T.; Brem, G.; Pfeffer, K.; Muller, M. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 2000, 13, 549-560.
-
(2000)
Immunity
, vol.13
, pp. 549-560
-
-
Karaghiosoff, M.1
Neubauer, H.2
Lassnig, C.3
Kovarik, P.4
Schindler, H.5
Pircher, H.6
McCoy, B.7
Bogdan, C.8
Decker, T.9
Brem, G.10
Pfeffer, K.11
Muller, M.12
-
56
-
-
0033711641
-
Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function
-
Shimoda, K.; Kato, K.; Aoki, K.; Matsuda, T.; Miyamoto, A.; Shibamori, M.; Yamashita, M.; Numata, A.; Takase, K.; Kobayashi, S.; Shibata, S.; Asano, Y.; Gondo, H.; Sekiguchi, K.; Nakayama, K.; Nakayama, T.; Okamura, T.; Okamura, S.; Niho, Y. Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function. Immunity 2000, 13, 561-571.
-
(2000)
Immunity
, vol.13
, pp. 561-571
-
-
Shimoda, K.1
Kato, K.2
Aoki, K.3
Matsuda, T.4
Miyamoto, A.5
Shibamori, M.6
Yamashita, M.7
Numata, A.8
Takase, K.9
Kobayashi, S.10
Shibata, S.11
Asano, Y.12
Gondo, H.13
Sekiguchi, K.14
Nakayama, K.15
Nakayama, T.16
Okamura, T.17
Okamura, S.18
Niho, Y.19
-
57
-
-
0028339282
-
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
-
Johnston, J.A.; Kawamura, M.; Kirken, R.A.; Chen, Y.Q.; Blake, T.B.; Shibuya, K.; Ortaldo, J.R.; McVicar, D.W.; O'Shea, J.J. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 1994, 370, 151-153.
-
(1994)
Nature
, vol.370
, pp. 151-153
-
-
Johnston, J.A.1
Kawamura, M.2
Kirken, R.A.3
Chen, Y.Q.4
Blake, T.B.5
Shibuya, K.6
Ortaldo, J.R.7
McVicar, D.W.8
O'Shea, J.J.9
-
58
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka, T.; van Deursen, J.M.; Tripp, R.A.; Thierfelder, W.E.; Witthuhn, B.A.; McMickle, A.P.; Doherty, P.C.; Grosveld, G.C.; Ihle, J.N. Defective lymphoid development in mice lacking Jak3. Science 1995, 270, 800-802.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
van Deursen, J.M.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
Doherty, P.C.7
Grosveld, G.C.8
Ihle, J.N.9
-
59
-
-
0028244396
-
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
-
Witthuhn, B.A.; Silvennoinen, O.; Miura, O.; Lai, K.S.; Cwik, C.; Liu, E.T.; Ihle, J.N. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 1994, 370, 153-157.
-
(1994)
Nature
, vol.370
, pp. 153-157
-
-
Witthuhn, B.A.1
Silvennoinen, O.2
Miura, O.3
Lai, K.S.4
Cwik, C.5
Liu, E.T.6
Ihle, J.N.7
-
60
-
-
26244463218
-
Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: Inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells
-
Lin, Q.; Lai, R.; Chirieac, L.R.; Li, C.; Thomazy, V.A.; Grammatikakis, I.; Rassidakis, G.Z.; Zhang, W.; Fujio, Y.; Kunisada, K.; Hamilton, S.R.; Amin, H.M. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: Inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. Am. J. Pathol. 2005, 167, 969-980.
-
(2005)
Am. J. Pathol
, vol.167
, pp. 969-980
-
-
Lin, Q.1
Lai, R.2
Chirieac, L.R.3
Li, C.4
Thomazy, V.A.5
Grammatikakis, I.6
Rassidakis, G.Z.7
Zhang, W.8
Fujio, Y.9
Kunisada, K.10
Hamilton, S.R.11
Amin, H.M.12
-
61
-
-
52449119447
-
Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers
-
Jeong, E.G.; Kim, M.S.; Nam, H.K.; Min, C.K.; Lee, S.; Chung, Y.J.; Yoo, N.J.; Lee, S.H. Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers. Clin. Cancer Res. 2008, 14, 3716-3721.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 3716-3721
-
-
Jeong, E.G.1
Kim, M.S.2
Nam, H.K.3
Min, C.K.4
Lee, S.5
Chung, Y.J.6
Yoo, N.J.7
Lee, S.H.8
-
62
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters, D.K.; Mercher, T.; Gu, T.L.; O'Hare, T.; Tyner, J.W.; Loriaux, M.; Goss, V.L.; Lee, K.A.; Eide, C.A.; Wong, M.J.; Stoffregen, E.P.; McGreevey, L.; Nardone, J.; Moore, S.A.; Crispino, J.; Boggon, T.J.; Heinrich, M.C.; Deininger, M.W.; Polakiewicz, R.D.; Gilliland, D.G.; Druker, B.J. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell 2006, 10, 65-75.
-
(2006)
Cancer Cell
, vol.10
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
O'Hare, T.4
Tyner, J.W.5
Loriaux, M.6
Goss, V.L.7
Lee, K.A.8
Eide, C.A.9
Wong, M.J.10
Stoffregen, E.P.11
McGreevey, L.12
Nardone, J.13
Moore, S.A.14
Crispino, J.15
Boggon, T.J.16
Heinrich, M.C.17
Deininger, M.W.18
Polakiewicz, R.D.19
Gilliland, D.G.20
Druker, B.J.21
more..
-
63
-
-
47149115129
-
Identification of somatic JAK1 mutations in patients with acute myeloid leukemia
-
Xiang, Z.; Zhao, Y.; Mitaksov, V.; Fremont, D.H.; Kasai, Y.; Molitoris, A.; Ries, R.E.; Miner, T.L.; McLellan, M.D.; DiPersio, J.F.; Link, D.C.; Payton, J.E.; Graubert, T.A.; Watson, M.; Shannon, W.; Heath, S.E.; Nagarajan, R.; Mardis, E.R.; Wilson, R.K.; Ley, T.J.; Tomasson, M.H. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood 2008, 111, 4809-4812.
-
(2008)
Blood
, vol.111
, pp. 4809-4812
-
-
Xiang, Z.1
Zhao, Y.2
Mitaksov, V.3
Fremont, D.H.4
Kasai, Y.5
Molitoris, A.6
Ries, R.E.7
Miner, T.L.8
McLellan, M.D.9
Dipersio, J.F.10
Link, D.C.11
Payton, J.E.12
Graubert, T.A.13
Watson, M.14
Shannon, W.15
Heath, S.E.16
Nagarajan, R.17
Mardis, E.R.18
Wilson, R.K.19
Ley, T.J.20
Tomasson, M.H.21
more..
-
64
-
-
42249091014
-
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
-
Flex, E.; Petrangeli, V.; Stella, L.; Chiaretti, S.; Hornakova, T.; Knoops, L.; Ariola, C.; Fodale, V.; Clappier, E.; Paoloni, F.; Martinelli, S.; Fragale, A.; Sanchez, M.; Tavolaro, S.; Messina, M.; Cazzaniga, G.; Camera, A.; Pizzolo, G.; Tornesello, A.; Vignetti, M.; Battistini, A.; Cave, H.; Gelb, B.D.; Renauld, J.C.; Biondi, A.; Constantinescu, S.N.; Foa, R.; Tartaglia, M. Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J. Exp. Med. 2008, 205, 751-758.
-
(2008)
J. Exp. Med
, vol.205
, pp. 751-758
-
-
Flex, E.1
Petrangeli, V.2
Stella, L.3
Chiaretti, S.4
Hornakova, T.5
Knoops, L.6
Ariola, C.7
Fodale, V.8
Clappier, E.9
Paoloni, F.10
Martinelli, S.11
Fragale, A.12
Sanchez, M.13
Tavolaro, S.14
Messina, M.15
Cazzaniga, G.16
Camera, A.17
Pizzolo, G.18
Tornesello, A.19
Vignetti, M.20
Battistini, A.21
Cave, H.22
Gelb, B.D.23
Renauld, J.C.24
Biondi, A.25
Constantinescu, S.N.26
Foa, R.27
Tartaglia, M.28
more..
-
65
-
-
0038386537
-
Jak family of kinases in cancer
-
Verma, A.; Kambhampati, S.; Parmar, S.; Platanias, L.C. Jak family of kinases in cancer. Cancer Metastasis Rev. 2003, 22, 423-434.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 423-434
-
-
Verma, A.1
Kambhampati, S.2
Parmar, S.3
Platanias, L.C.4
-
66
-
-
34548240698
-
Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders. Nat
-
Levine, R.L.; Pardanani, A.; Tefferi, A.; Gilliland, D.G. Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders. Nat. Rev. Cancer 2007, 7, 673-683.
-
(2007)
Rev. Cancer
, vol.7
, pp. 673-683
-
-
Levine, R.L.1
Pardanani, A.2
Tefferi, A.3
Gilliland, D.G.4
-
67
-
-
70350494529
-
JAK2 gets histone H3 rolling
-
Sattler, M.; Griffin, J.D. JAK2 gets histone H3 rolling. Cancer Cell 2009, 16, 365-366.
-
(2009)
Cancer Cell
, vol.16
, pp. 365-366
-
-
Sattler, M.1
Griffin, J.D.2
-
68
-
-
70349975711
-
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin
-
Dawson, M.A.; Bannister, A.J.; Gottgens, B.; Foster, S.D.; Bartke, T.; Green, A.R.; Kouzarides, T. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature 2009, 461, 819-822.
-
(2009)
Nature
, vol.461
, pp. 819-822
-
-
Dawson, M.A.1
Bannister, A.J.2
Gottgens, B.3
Foster, S.D.4
Bartke, T.5
Green, A.R.6
Kouzarides, T.7
-
69
-
-
0033559793
-
Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3-receptor interaction domain
-
Cacalano, N.A.; Migone, T.S.; Bazan, F.; Hanson, E.P.; Chen, M.; Candotti, F.; O'Shea, J.J.; Johnston, J.A. Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3-receptor interaction domain. EMBO J. 1999, 18, 1549-1558.
-
(1999)
EMBO J
, vol.18
, pp. 1549-1558
-
-
Cacalano, N.A.1
Migone, T.S.2
Bazan, F.3
Hanson, E.P.4
Chen, M.5
Candotti, F.6
O'Shea, J.J.7
Johnston, J.A.8
-
70
-
-
34547108380
-
JAK-STAT signaling: From interferons to cytokines
-
Schindler, C.; Levy, D.E.; Decker, T. JAK-STAT signaling: From interferons to cytokines. J. Biol. Chem. 2007, 282, 20059-20063.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
71
-
-
30444458235
-
Stats: Multifaceted regulators of transcription
-
Brierley, M.M.; Fish, E.N. Stats: Multifaceted regulators of transcription. J. Interferon Cytokine Res. 2005, 25, 733-744.
-
(2005)
J. Interferon Cytokine Res
, vol.25
, pp. 733-744
-
-
Brierley, M.M.1
Fish, E.N.2
-
72
-
-
0037177813
-
Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727
-
Uddin, S.; Sassano, A.; Deb, D.K.; Verma, A.; Majchrzak, B.; Rahman, A.; Malik, A.B.; Fish, E.N.; Platanias, L.C. Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J. Biol. Chem. 2002, 277, 14408-14416.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 14408-14416
-
-
Uddin, S.1
Sassano, A.2
Deb, D.K.3
Verma, A.4
Majchrzak, B.5
Rahman, A.6
Malik, A.B.7
Fish, E.N.8
Platanias, L.C.9
-
73
-
-
0030670639
-
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1
-
Sekimoto, T.; Imamoto, N.; Nakajima, K.; Hirano, T.; Yoneda, Y. Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J. 1997, 16, 7067-7077.
-
(1997)
EMBO J
, vol.16
, pp. 7067-7077
-
-
Sekimoto, T.1
Imamoto, N.2
Nakajima, K.3
Hirano, T.4
Yoneda, Y.5
-
74
-
-
0037007207
-
Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha
-
McBride, K.M.; Banninger, G.; McDonald, C.; Reich, N.C. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha. EMBO J. 2002, 21, 1754-1763.
-
(2002)
EMBO J
, vol.21
, pp. 1754-1763
-
-
McBride, K.M.1
Banninger, G.2
McDonald, C.3
Reich, N.C.4
-
75
-
-
33746570647
-
Tracking STAT nuclear traffic
-
Reich, N.C.; Liu, L. Tracking STAT nuclear traffic. Nat. Rev. Immunol. 2006, 6, 602-612.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 602-612
-
-
Reich, N.C.1
Liu, L.2
-
76
-
-
0034669111
-
Nuclear export signal located within theDNA- binding domain of the STAT1transcription factor
-
McBride, K.M.; McDonald, C.; Reich, N.C. Nuclear export signal located within theDNA- binding domain of the STAT1transcription factor. EMBO J. 2000, 19, 6196-6206.
-
(2000)
EMBO J
, vol.19
, pp. 6196-6206
-
-
McBride, K.M.1
McDonald, C.2
Reich, N.C.3
-
77
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H.; Pardoll, D.; Jove, R. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 2009, 9, 798-809.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
78
-
-
0038820386
-
Signal transducer and activator of transcription proteins in leukemias
-
Benekli, M.; Baer, M.R.; Baumann, H.; Wetzler, M. Signal transducer and activator of transcription proteins in leukemias. Blood 2003, 101, 2940-2954.
-
(2003)
Blood
, vol.101
, pp. 2940-2954
-
-
Benekli, M.1
Baer, M.R.2
Baumann, H.3
Wetzler, M.4
-
79
-
-
0034658698
-
STATs in oncogenesis
-
Bowman, T.; Garcia, R.; Turkson, J.; Jove, R. STATs in oncogenesis. Oncogene 2000, 19, 2474-2488.
-
(2000)
Oncogene
, vol.19
, pp. 2474-2488
-
-
Bowman, T.1
Garcia, R.2
Turkson, J.3
Jove, R.4
-
80
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy, D.E.; Darnell, J.E. Stats: Transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 2002, 3, 651-662.
-
(2002)
Nat. Rev. Mol. Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell, J.E.2
-
81
-
-
34548167742
-
STAT1- dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha
-
Zimmerer, J.M.; Lesinski, G.B.; Radmacher, M.D.; Ruppert, A.; Carson, W.E. STAT1- dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha. Cancer Immunol. Immunother. 2007, 56, 1845-1852.
-
(2007)
Cancer Immunol. Immunother
, vol.56
, pp. 1845-1852
-
-
Zimmerer, J.M.1
Lesinski, G.B.2
Radmacher, M.D.3
Ruppert, A.4
Carson, W.E.5
-
82
-
-
0035854542
-
Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
-
Dupuis, S.; Dargemont, C.; Fieschi, C.; Thomassin, N.; Rosenzweig, S.; Harris, J.; Holland, S.M.; Schreiber, R.D.; Casanova, J.L. Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 2001, 293, 300-303.
-
(2001)
Science
, vol.293
, pp. 300-303
-
-
Dupuis, S.1
Dargemont, C.2
Fieschi, C.3
Thomassin, N.4
Rosenzweig, S.5
Harris, J.6
Holland, S.M.7
Schreiber, R.D.8
Casanova, J.L.9
-
83
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M.A.; White, J.M.; Sheehan, K.C.; Bach, E.A.; Rodig, S.J.; Dighe, A.S.; Kaplan, D.H.; Riley, J.K.; Greenlund, A.C.; Campbell, D.; Carver-Moore, K.; DuBois, R.N.; Clark, R.; Aguet, M.; Schreiber, R.D. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996, 84, 431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
Carver-Moore, K.11
Dubois, R.N.12
Clark, R.13
Aguet, M.14
Schreiber, R.D.15
-
84
-
-
0034292328
-
Distinct requirements for IFNs and STAT1 in NK cell function
-
Lee, C.K.; Rao, D.T.; Gertner, R.; Gimeno, R.; Frey, A.B.; Levy, D.E. Distinct requirements for IFNs and STAT1 in NK cell function. J. Immunol. 2000, 165, 3571-3577.
-
(2000)
J. Immunol
, vol.165
, pp. 3571-3577
-
-
Lee, C.K.1
Rao, D.T.2
Gertner, R.3
Gimeno, R.4
Frey, A.B.5
Levy, D.E.6
-
85
-
-
30344461860
-
The p38 mitogen-activated protein kinase pathway in interferon signal transduction
-
Katsoulidis, E.; Li, Y.; Mears, H.; Platanias, L.C. The p38 mitogen-activated protein kinase pathway in interferon signal transduction. J. Interferon Cytokine Res. 2005, 25, 749-756.
-
(2005)
J. Interferon Cytokine Res
, vol.25
, pp. 749-756
-
-
Katsoulidis, E.1
Li, Y.2
Mears, H.3
Platanias, L.C.4
-
86
-
-
0037406263
-
The p38 mitogen-activated protein kinase pathway and its role in interferon signaling. Pharmacol
-
Platanias, L.C. The p38 mitogen-activated protein kinase pathway and its role in interferon signaling. Pharmacol. Ther. 2003, 98, 129-142.
-
(2003)
Ther
, vol.98
, pp. 129-142
-
-
Platanias, L.C.1
-
87
-
-
0032727032
-
Signaling pathways activated by interferons
-
Platanias, L.C.; Fish, E.N. Signaling pathways activated by interferons. Exp. Hematol. 1999, 27, 1583-1592.
-
(1999)
Exp. Hematol
, vol.27
, pp. 1583-1592
-
-
Platanias, L.C.1
Fish, E.N.2
-
88
-
-
0036232326
-
Signaling via the interferon-alpha receptor in chronic myelogenous leukemia cells
-
Verma, A.; Platanias, L.C. Signaling via the interferon-alpha receptor in chronic myelogenous leukemia cells. Leuk. Lymphoma 2002, 43, 703-709.
-
(2002)
Leuk. Lymphoma
, vol.43
, pp. 703-709
-
-
Verma, A.1
Platanias, L.C.2
-
89
-
-
44849101524
-
Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells
-
Katsoulidis, E.; Sassano, A.; Majchrzak-Kita, B.; Carayol, N.; Yoon, P.; Jordan, A.; Druker, B.J.; Fish, E.N.; Platanias, L.C. Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells. J. Biol. Chem. 2008, 283, 10793-10803.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 10793-10803
-
-
Katsoulidis, E.1
Sassano, A.2
Majchrzak-Kita, B.3
Carayol, N.4
Yoon, P.5
Jordan, A.6
Druker, B.J.7
Fish, E.N.8
Platanias, L.C.9
-
90
-
-
2942558439
-
Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells
-
Parmar, S.; Katsoulidis, E.; Verma, A.; Li, Y.; Sassano, A.; Lal, L.; Majchrzak, B.; Ravandi, F.; Tallman, M.S.; Fish, E.N.; Platanias, L.C. Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells. J. Biol. Chem. 2004, 279, 25345-25352.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 25345-25352
-
-
Parmar, S.1
Katsoulidis, E.2
Verma, A.3
Li, Y.4
Sassano, A.5
Lal, L.6
Majchrzak, B.7
Ravandi, F.8
Tallman, M.S.9
Fish, E.N.10
Platanias, L.C.11
-
91
-
-
0038264431
-
Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors
-
Wong, S.; McLaughlin, J.; Cheng, D.; Witte, O.N. Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors. Blood 2003, 101, 4088-4097.
-
(2003)
Blood
, vol.101
, pp. 4088-4097
-
-
Wong, S.1
McLaughlin, J.2
Cheng, D.3
Witte, O.N.4
-
92
-
-
0036401775
-
Low expression of interferon regulatory factor-1 and identification of novel exons skipping in patients with chronic myeloid leukaemia
-
Tzoanopoulos, D.; Speletas, M.; Arvanitidis, K.; Veiopoulou, C.; Kyriaki, S.; Thyphronitis, G.; Sideras, P.; Kartalis, G.; Ritis, K. Low expression of interferon regulatory factor-1 and identification of novel exons skipping in patients with chronic myeloid leukaemia. Br. J. Haematol. 2002, 119, 46-53.
-
(2002)
Br. J. Haematol
, vol.119
, pp. 46-53
-
-
Tzoanopoulos, D.1
Speletas, M.2
Arvanitidis, K.3
Veiopoulou, C.4
Kyriaki, S.5
Thyphronitis, G.6
Sideras, P.7
Kartalis, G.8
Ritis, K.9
-
93
-
-
33751257187
-
The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe?
-
Andersen, J.B.; Hassel, B.A. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe? Cytokine Growth Factor Rev. 2006, 17, 411-421.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 411-421
-
-
Andersen, J.B.1
Hassel, B.A.2
-
94
-
-
28544435897
-
Immunity by ubiquitylation: A reversible process of modification
-
Liu, Y.C.; Penninger, J.; Karin, M. Immunity by ubiquitylation: A reversible process of modification. Nat. Rev. Immunol. 2005, 5, 941-952.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 941-952
-
-
Liu, Y.C.1
Penninger, J.2
Karin, M.3
-
95
-
-
65849226334
-
The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer
-
Bektas, N.; Noetzel, E.; Veeck, J.; Press, M.F.; Kristiansen, G.; Naami, A.; Hartmann, A.; Dimmler, A.; Beckmann, M.W.; Knuchel, R.; Fasching, P.A.; Dahl, E. The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer. Breast Cancer Res. 2008, 10, R58.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Bektas, N.1
Noetzel, E.2
Veeck, J.3
Press, M.F.4
Kristiansen, G.5
Naami, A.6
Hartmann, A.7
Dimmler, A.8
Beckmann, M.W.9
Knuchel, R.10
Fasching, P.A.11
Dahl, E.12
-
96
-
-
0027180655
-
gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme
-
Kok, K.; Hofstra, R.; Pilz, A.; van den Berg, A.; Terpstra, P.; Buys, C.H.; Carritt, B. A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme. Proc. Natl. Acad. Sci. USA 1993, 90, 6071-6075.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6071-6075
-
-
Kok, K.1
Hofstra, R.2
Pilz, A.3
van den Berg, A.4
Terpstra, P.5
Buys, C.H.6
Carritt, B.A.7
-
97
-
-
0037443090
-
Protein ISGylation modulates the JAK-STAT signaling pathway
-
Malakhova, O.A.; Yan, M.; Malakhov, M.P.; Yuan, Y.; Ritchie, K.J.; Kim, K.I.; Peterson, L.F.; Shuai, K.; Zhang, D.E. Protein ISGylation modulates the JAK-STAT signaling pathway. Genes Dev. 2003, 17, 455-460.
-
(2003)
Genes Dev
, vol.17
, pp. 455-460
-
-
Malakhova, O.A.1
Yan, M.2
Malakhov, M.P.3
Yuan, Y.4
Ritchie, K.J.5
Kim, K.I.6
Peterson, L.F.7
Shuai, K.8
Zhang, D.E.9
-
98
-
-
0035906250
-
Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH
-
Kang, D.; Jiang, H.; Wu, Q.; Pestka, S.; Fisher, P.B. Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH. Gene 2001, 267, 233-242.
-
(2001)
Gene
, vol.267
, pp. 233-242
-
-
Kang, D.1
Jiang, H.2
Wu, Q.3
Pestka, S.4
Fisher, P.B.5
-
99
-
-
42449150892
-
Role of the Akt pathway in mRNA translation of interferon-stimulated genes
-
Kaur, S.; Sassano, A.; Dolniak, B.; Joshi, S.; Majchrzak-Kita, B.; Baker, D.P.; Hay, N.; Fish, E.N.; Platanias, L.C. Role of the Akt pathway in mRNA translation of interferon-stimulated genes. Proc. Natl. Acad. Sci. USA 2008, 105, 4808-4813.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4808-4813
-
-
Kaur, S.1
Sassano, A.2
Dolniak, B.3
Joshi, S.4
Majchrzak-Kita, B.5
Baker, D.P.6
Hay, N.7
Fish, E.N.8
Platanias, L.C.9
-
100
-
-
47749140740
-
Akt and mRNA translation by interferons
-
Kaur, S.; Katsoulidis, E.; Platanias, L.C. Akt and mRNA translation by interferons. Cell Cycle 2008, 7, 2112-2116.
-
(2008)
Cell Cycle
, vol.7
, pp. 2112-2116
-
-
Kaur, S.1
Katsoulidis, E.2
Platanias, L.C.3
-
101
-
-
30344464664
-
The PI3' kinase pathway in interferon signaling
-
Kaur, S.; Uddin, S.; Platanias, L.C. The PI3' kinase pathway in interferon signaling. J. Interferon Cytokine Res. 2005, 25, 780-787.
-
(2005)
J. Interferon Cytokine Res
, vol.25
, pp. 780-787
-
-
Kaur, S.1
Uddin, S.2
Platanias, L.C.3
-
102
-
-
47649124617
-
Protein kinase C signalling in leukemia
-
Redig, A.J.; Platanias, L.C. Protein kinase C signalling in leukemia. Leuk. Lymphoma 2008, 49, 1255-1262.
-
(2008)
Leuk. Lymphoma
, vol.49
, pp. 1255-1262
-
-
Redig, A.J.1
Platanias, L.C.2
-
103
-
-
0036595049
-
Suppressors of cytokine signalling (SOCS) in the immune system. Nat
-
Alexander, W.S. Suppressors of cytokine signalling (SOCS) in the immune system. Nat. Rev. Immunol. 2002, 2, 410-416.
-
(2002)
Rev. Immunol
, vol.2
, pp. 410-416
-
-
Alexander, W.S.1
|