Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: Inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells

American Journal of Pathology

Volumn 167, Issue 4, 2005, Pages 969-980

  Lin, Quan ^a   Lai, Raymond ^b   Chirieac, Lucian R ^a   Li, Changping ^a   Thomazy, Vilmos A ^a   Grammatikakis, Ioannis ^a   Rassidakis, George Z ^a   Zhang, Wei ^a   Fujio, Yasushi ^c   Kunisada, Keita ^c   Hamilton, Stanley R ^a   Amin, Hesham M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D2; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; JANUS KINASE 3; MESSENGER RNA; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CARCINOGENESIS; CELL CYCLE; CELL VIABILITY; CLINICAL ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 26244463218     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61187-X     Document Type: Article

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