Structural analysis of a helical peptide unfolding pathway

Chemistry - A European Journal

Volumn 16, Issue 18, 2010, Pages 5400-5407

  Diana, Donatella ^a   Ziaco, Barbara ^a   Scarabelli, Guido ^b   Pedone, Carlo ^c   Colombo, Giorgio ^b   D'Andrea, Luca D ^a   Fattorusso, Roberto ^a,d  

^a CNR   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Molecular dynamics; NMR spectroscopy; Protein design; Protein folding; Thermal stability

Indexed keywords

ATOMIC RESOLUTION; COMPUTATIONAL ANALYSIS; CONFORMATIONAL PREFERENCES; EXPERIMENTAL OBSERVATION; FOLDING MECHANISM; HELICAL PEPTIDE; HELIX NUCLEATION; HIGH RESOLUTION; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR SCAFFOLDS; NMR SPECTROSCOPY; PROPAGATION MODELS; PROTEIN DESIGN; SECOND PHASE; SECONDARY STRUCTURES; TARGET PROTEINS; TEMPERATURE DEPENDENCIES; TERMINAL REGIONS; THERMAL STABILITY; THERMAL UNFOLDING; VASCULAR ENDOTHELIAL GROWTH FACTOR;

DATA FLOW ANALYSIS; DESIGN; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEATION; PROTEIN FOLDING; STRUCTURAL ANALYSIS; THERMODYNAMIC STABILITY; THERMOGRAVIMETRIC ANALYSIS;

PEPTIDES;

AMINO ACID; OLIGOPEPTIDE; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; COMPUTER SIMULATION; HYDROGEN BOND; METHODOLOGY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SYNTHESIS; THERMODYNAMICS;

AMINO ACID SEQUENCE; AMINO ACIDS; CIRCULAR DICHROISM; COMPUTER SIMULATION; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; OLIGOPEPTIDES; PEPTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

EID: 77952111077     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200903428     Document Type: Article

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