메뉴 건너뛰기




Volumn 704, Issue 1-3, 2010, Pages 182-189

Molecular therapy in support to radiotherapy

Author keywords

Molecular therapy; Oligonucleotides; Radiotherapy; shRNA; siDNA; siRNA

Indexed keywords

ACICLOVIR; ADENOVIRUS VECTOR; ANTISENSE OLIGONUCLEOTIDE; BRCA1 PROTEIN; BRCA2 PROTEIN; CEREPRO; CETUXIMAB; CISPLATIN; CPG OLIGODEOXYNUCLEOTIDE; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROURACIL; GENCIDINE; GLIATAK; IBRITUMOMAB TIUXETAN; IODINE 131; KU ANTIGEN; LERAFAON; OLIGONUCLEOTIDE; ONYX 015; PANCATAK; PEROXIREDOXIN 1; PROSTATAK; PROTEIN P53; RAD51 PROTEIN; RAD54 PROTEIN; RAF PROTEIN; RIBONUCLEASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; SODIUM IODIDE SYMPORTER; THYMIDINE KINASE; TNFERADE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 77951977223     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrrev.2010.01.001     Document Type: Review
Times cited : (31)

References (94)
  • 2
    • 0345688619 scopus 로고    scopus 로고
    • Introduction to resistance to anticancer agents
    • Kruh G.D. Introduction to resistance to anticancer agents. Oncogene 22 (2003) 7262-7264
    • (2003) Oncogene , vol.22 , pp. 7262-7264
    • Kruh, G.D.1
  • 3
    • 1542299242 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance
    • Perona R., and Sanchez-Perez I. Control of oncogenesis and cancer therapy resistance. Br. J. Cancer 90 (2004) 573-577
    • (2004) Br. J. Cancer , vol.90 , pp. 573-577
    • Perona, R.1    Sanchez-Perez, I.2
  • 4
    • 47949097524 scopus 로고    scopus 로고
    • Biomarkers for DNA DSB inhibitors and radiotherapy clinical trials
    • Liu S.K., Olive P.L., and Bristow R.G. Biomarkers for DNA DSB inhibitors and radiotherapy clinical trials. Cancer Metastasis Rev. 27 (2008) 445-458
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 445-458
    • Liu, S.K.1    Olive, P.L.2    Bristow, R.G.3
  • 5
    • 68249108128 scopus 로고    scopus 로고
    • Targeting the DNA damage response for cancer therapy
    • Powell S.N., and Bindra R.S. Targeting the DNA damage response for cancer therapy. DNA Repair (Amst) 8 (2009) 1153-1165
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1153-1165
    • Powell, S.N.1    Bindra, R.S.2
  • 6
    • 68549087056 scopus 로고    scopus 로고
    • Viral vectors: from virology to transgene expression
    • Bouard D., Alazard-Dany D., and Cosset F.L. Viral vectors: from virology to transgene expression. Br. J. Pharmacol. 157 (2009) 153-165
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 153-165
    • Bouard, D.1    Alazard-Dany, D.2    Cosset, F.L.3
  • 7
    • 0035030198 scopus 로고    scopus 로고
    • Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors
    • Galanis E., Vile R., and Russell S.J. Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors. Crit. Rev. Oncol. Hematol. 38 (2001) 177-192
    • (2001) Crit. Rev. Oncol. Hematol. , vol.38 , pp. 177-192
    • Galanis, E.1    Vile, R.2    Russell, S.J.3
  • 8
    • 0031034030 scopus 로고    scopus 로고
    • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
    • Worgall S., Wolff G., Falck-Pedersen E., and Crystal R.G. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum. Gene Ther. 8 (1997) 37-44
    • (1997) Hum. Gene Ther. , vol.8 , pp. 37-44
    • Worgall, S.1    Wolff, G.2    Falck-Pedersen, E.3    Crystal, R.G.4
  • 9
    • 0032700656 scopus 로고    scopus 로고
    • Molecular mechanisms of action of antisense drugs
    • Crooke S.T. Molecular mechanisms of action of antisense drugs. Biochim. Biophys. Acta 1489 (1999) 31-44
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 31-44
    • Crooke, S.T.1
  • 10
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: the case for an RNase H-independent structural type
    • Summerton J. Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489 (1999) 141-158
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 141-158
    • Summerton, J.1
  • 11
    • 0033919830 scopus 로고    scopus 로고
    • Antisense peptide nucleic acids
    • Nielsen P.E. Antisense peptide nucleic acids. Curr. Opin. Mol. Ther. 2 (2000) 282-287
    • (2000) Curr. Opin. Mol. Ther. , vol.2 , pp. 282-287
    • Nielsen, P.E.1
  • 12
    • 33645808435 scopus 로고    scopus 로고
    • Locked nucleic acid: high-affinity targeting of complementary RNA for RNomics
    • Kauppinen S., Vester B., and Wengel J. Locked nucleic acid: high-affinity targeting of complementary RNA for RNomics. Handb. Exp. Pharmacol. (2006) 405-422
    • (2006) Handb. Exp. Pharmacol. , pp. 405-422
    • Kauppinen, S.1    Vester, B.2    Wengel, J.3
  • 15
    • 4344594013 scopus 로고    scopus 로고
    • Recent applications of RNAi in mammalian systems
    • Scherer L., and Rossi J.J. Recent applications of RNAi in mammalian systems. Curr. Pharm. Biotechnol. 5 (2004) 355-360
    • (2004) Curr. Pharm. Biotechnol. , vol.5 , pp. 355-360
    • Scherer, L.1    Rossi, J.J.2
  • 16
    • 0037238848 scopus 로고    scopus 로고
    • Gene silencing mediated by small interfering RNAs in mammalian cells
    • Scherr M., Morgan M.A., and Eder M. Gene silencing mediated by small interfering RNAs in mammalian cells. Curr. Med. Chem. 10 (2003) 245-256
    • (2003) Curr. Med. Chem. , vol.10 , pp. 245-256
    • Scherr, M.1    Morgan, M.A.2    Eder, M.3
  • 17
    • 25144498128 scopus 로고    scopus 로고
    • In vivo application of RNA interference: from functional genomics to therapeutics
    • Lu P.Y., Xie F., and Woodle M.C. In vivo application of RNA interference: from functional genomics to therapeutics. Adv. Genet. 54 (2005) 117-142
    • (2005) Adv. Genet. , vol.54 , pp. 117-142
    • Lu, P.Y.1    Xie, F.2    Woodle, M.C.3
  • 18
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg A.M. Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov. 5 (2006) 471-484
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 19
    • 61749098024 scopus 로고    scopus 로고
    • Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
    • Vollmer J., and Krieg A.M. Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. Adv. Drug Deliv. Rev. 61 (2009) 195-204
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 195-204
    • Vollmer, J.1    Krieg, A.M.2
  • 20
    • 11344265206 scopus 로고    scopus 로고
    • Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy
    • Mason K.A., Ariga H., Neal R., Valdecanas D., Hunter N., Krieg A.M., Whisnant J.K., and Milas L. Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy. Clin. Cancer Res. 11 (2005) 361-369
    • (2005) Clin. Cancer Res. , vol.11 , pp. 361-369
    • Mason, K.A.1    Ariga, H.2    Neal, R.3    Valdecanas, D.4    Hunter, N.5    Krieg, A.M.6    Whisnant, J.K.7    Milas, L.8
  • 22
    • 67651251435 scopus 로고    scopus 로고
    • Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response
    • Quanz M., Chassoux D., Berthault N., Agrario C., Sun J.S., and Dutreix M. Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response. PLoS One 4 (2009) e6298
    • (2009) PLoS One , vol.4
    • Quanz, M.1    Chassoux, D.2    Berthault, N.3    Agrario, C.4    Sun, J.S.5    Dutreix, M.6
  • 24
    • 0035989886 scopus 로고    scopus 로고
    • Oligonucleotide conjugates as potential antisense drugs with improved uptake, biodistribution, targeted delivery, and mechanism of action
    • Manoharan M. Oligonucleotide conjugates as potential antisense drugs with improved uptake, biodistribution, targeted delivery, and mechanism of action. Antisense Nucleic Acid Drug Dev. 12 (2002) 103-128
    • (2002) Antisense Nucleic Acid Drug Dev. , vol.12 , pp. 103-128
    • Manoharan, M.1
  • 26
    • 47249138782 scopus 로고    scopus 로고
    • Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
    • Juliano R., Alam M.R., Dixit V., and Kang H. Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res. 36 (2008) 4158-4171
    • (2008) Nucleic Acids Res. , vol.36 , pp. 4158-4171
    • Juliano, R.1    Alam, M.R.2    Dixit, V.3    Kang, H.4
  • 27
    • 34248672837 scopus 로고    scopus 로고
    • Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity
    • Akhtar S., and Benter I. Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity. Adv. Drug Deliv. Rev. 59 (2007) 164-182
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 164-182
    • Akhtar, S.1    Benter, I.2
  • 28
    • 67249096677 scopus 로고    scopus 로고
    • Nonviral methods for siRNA delivery
    • Gao K., and Huang L. Nonviral methods for siRNA delivery. Mol. Pharm. 6 (2009) 651-658
    • (2009) Mol. Pharm. , vol.6 , pp. 651-658
    • Gao, K.1    Huang, L.2
  • 29
    • 67249122712 scopus 로고    scopus 로고
    • Biological barriers to therapy with antisense and siRNA oligonucleotides
    • Juliano R., Bauman J., Kang H., and Ming X. Biological barriers to therapy with antisense and siRNA oligonucleotides. Mol. Pharm. 6 (2009) 686-695
    • (2009) Mol. Pharm. , vol.6 , pp. 686-695
    • Juliano, R.1    Bauman, J.2    Kang, H.3    Ming, X.4
  • 31
    • 0642374221 scopus 로고    scopus 로고
    • The role of glutathione-S-transferase in anti-cancer drug resistance
    • Townsend D.M., and Tew K.D. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22 (2003) 7369-7375
    • (2003) Oncogene , vol.22 , pp. 7369-7375
    • Townsend, D.M.1    Tew, K.D.2
  • 34
    • 0029777311 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature
    • Mauceri H.J., Hanna N.N., Wayne J.D., Hallahan D.E., Hellman S., and Weichselbaum R.R. Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature. Cancer Res. 56 (1996) 4311-4314
    • (1996) Cancer Res. , vol.56 , pp. 4311-4314
    • Mauceri, H.J.1    Hanna, N.N.2    Wayne, J.D.3    Hallahan, D.E.4    Hellman, S.5    Weichselbaum, R.R.6
  • 35
    • 0024561558 scopus 로고
    • The role of oxidant injury in tumor cell sensitivity to recombinant human tumor necrosis factor in vivo. Implications for mechanisms of action
    • Zimmerman R.J., Marafino Jr. B.J., Chan A., Landre P., and Winkelhake J.L. The role of oxidant injury in tumor cell sensitivity to recombinant human tumor necrosis factor in vivo. Implications for mechanisms of action. J. Immunol. 142 (1989) 1405-1409
    • (1989) J. Immunol. , vol.142 , pp. 1405-1409
    • Zimmerman, R.J.1    Marafino Jr., B.J.2    Chan, A.3    Landre, P.4    Winkelhake, J.L.5
  • 36
    • 0025359095 scopus 로고
    • The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines
    • Hallahan D.E., Beckett M.A., Kufe D., and Weichselbaum R.R. The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines. Int. J. Radiat. Oncol. Biol. Phys. 19 (1990) 69-74
    • (1990) Int. J. Radiat. Oncol. Biol. Phys. , vol.19 , pp. 69-74
    • Hallahan, D.E.1    Beckett, M.A.2    Kufe, D.3    Weichselbaum, R.R.4
  • 37
    • 0028358574 scopus 로고
    • Interaction of tumour necrosis factor-alpha and radiation against human colon tumour cells
    • Gridley D.S., Glisson W.C., and Uhm J.R. Interaction of tumour necrosis factor-alpha and radiation against human colon tumour cells. Ther. Immunol. 1 (1994) 25-31
    • (1994) Ther. Immunol. , vol.1 , pp. 25-31
    • Gridley, D.S.1    Glisson, W.C.2    Uhm, J.R.3
  • 39
    • 0023676391 scopus 로고
    • Anti-tumor effects of tumor necrosis factor alone or combined with radiotherapy
    • Sersa G., Willingham V., and Milas L. Anti-tumor effects of tumor necrosis factor alone or combined with radiotherapy. Int. J. Cancer 42 (1988) 129-134
    • (1988) Int. J. Cancer , vol.42 , pp. 129-134
    • Sersa, G.1    Willingham, V.2    Milas, L.3
  • 40
    • 0028352823 scopus 로고
    • Effects of radiolabelled murine antibody infusion on TNF-alpha, IL-1 beta, and soluble IL-2 receptor in cancer patients
    • Gridley D.S., Hammond S.N., and Slater J.M. Effects of radiolabelled murine antibody infusion on TNF-alpha, IL-1 beta, and soluble IL-2 receptor in cancer patients. J. Clin. Lab. Anal. 8 (1994) 223-227
    • (1994) J. Clin. Lab. Anal. , vol.8 , pp. 223-227
    • Gridley, D.S.1    Hammond, S.N.2    Slater, J.M.3
  • 41
    • 0025350957 scopus 로고
    • Tumor necrosis factor as an adjunct to fractionated radiotherapy in the treatment of murine tumors
    • Nishiguchi I., Willingham V., and Milas L. Tumor necrosis factor as an adjunct to fractionated radiotherapy in the treatment of murine tumors. Int. J. Radiat. Oncol. Biol. Phys. 18 (1990) 555-558
    • (1990) Int. J. Radiat. Oncol. Biol. Phys. , vol.18 , pp. 555-558
    • Nishiguchi, I.1    Willingham, V.2    Milas, L.3
  • 42
    • 67651115664 scopus 로고    scopus 로고
    • Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers
    • Weichselbaum R.R., and Kufe D. Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers. Cancer Gene Ther. 16 (2009) 609-619
    • (2009) Cancer Gene Ther. , vol.16 , pp. 609-619
    • Weichselbaum, R.R.1    Kufe, D.2
  • 43
    • 71549168293 scopus 로고    scopus 로고
    • Peroxiredoxins, a novel target in cancer radiotherapy
    • Zhang B., Wang Y., and Su Y. Peroxiredoxins, a novel target in cancer radiotherapy. Cancer Lett. (2009)
    • (2009) Cancer Lett.
    • Zhang, B.1    Wang, Y.2    Su, Y.3
  • 45
    • 0347478188 scopus 로고    scopus 로고
    • Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues
    • Kim H.J., Chae H.Z., Kim Y.J., Kim Y.H., Hwangs T.S., Park E.M., and Park Y.M. Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues. Cell Biol. Toxicol. 19 (2003) 285-298
    • (2003) Cell Biol. Toxicol. , vol.19 , pp. 285-298
    • Kim, H.J.1    Chae, H.Z.2    Kim, Y.J.3    Kim, Y.H.4    Hwangs, T.S.5    Park, E.M.6    Park, Y.M.7
  • 48
    • 37849032288 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of siRNA against peroxiredoxin I enhances the radiosensitivity of human intestinal cancer
    • Zhang B., Wang Y., Liu K., Yang X., Song M., and Bai Y. Adenovirus-mediated transfer of siRNA against peroxiredoxin I enhances the radiosensitivity of human intestinal cancer. Biochem. Pharmacol. 75 (2008) 660-667
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 660-667
    • Zhang, B.1    Wang, Y.2    Liu, K.3    Yang, X.4    Song, M.5    Bai, Y.6
  • 52
    • 0024580323 scopus 로고
    • Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma
    • Kasid U., Pfeifer A., Brennan T., Beckett M., Weichselbaum R.R., Dritschilo A., and Mark G.E. Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma. Science 243 (1989) 1354-1356
    • (1989) Science , vol.243 , pp. 1354-1356
    • Kasid, U.1    Pfeifer, A.2    Brennan, T.3    Beckett, M.4    Weichselbaum, R.R.5    Dritschilo, A.6    Mark, G.E.7
  • 53
    • 0031450606 scopus 로고    scopus 로고
    • Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer
    • Gokhale P.C., Soldatenkov V., Wang F.H., Rahman A., Dritschilo A., and Kasid U. Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer. Gene Ther. 4 (1997) 1289-1299
    • (1997) Gene Ther. , vol.4 , pp. 1289-1299
    • Gokhale, P.C.1    Soldatenkov, V.2    Wang, F.H.3    Rahman, A.4    Dritschilo, A.5    Kasid, U.6
  • 55
    • 0030894324 scopus 로고    scopus 로고
    • Inhibition of Raf-1 protein kinase by antisense phosphorothioate oligodeoxyribonucleotide is associated with sensitization of human laryngeal squamous carcinoma cells to gamma radiation
    • Soldatenkov V.A., Dritschilo A., Wang F.H., Olah Z., Anderson W.B., and Kasid U. Inhibition of Raf-1 protein kinase by antisense phosphorothioate oligodeoxyribonucleotide is associated with sensitization of human laryngeal squamous carcinoma cells to gamma radiation. Cancer J. Sci. Am. 3 (1997) 13-20
    • (1997) Cancer J. Sci. Am. , vol.3 , pp. 13-20
    • Soldatenkov, V.A.1    Dritschilo, A.2    Wang, F.H.3    Olah, Z.4    Anderson, W.B.5    Kasid, U.6
  • 57
    • 0029460645 scopus 로고
    • Gene therapy of human pancreatic carcinoma by recombinant retroviral vector expressing herpes simplex virus thymidine kinase gene
    • Li H., Liu T., and Wang Z. Gene therapy of human pancreatic carcinoma by recombinant retroviral vector expressing herpes simplex virus thymidine kinase gene. Zhonghua Bing Li Xue Za Zhi 24 (1995) 345-347
    • (1995) Zhonghua Bing Li Xue Za Zhi , vol.24 , pp. 345-347
    • Li, H.1    Liu, T.2    Wang, Z.3
  • 58
    • 0029018605 scopus 로고
    • Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter
    • Ido A., Nakata K., Kato Y., Nakao K., Murata K., Fujita M., Ishii N., Tamaoki T., Shiku H., and Nagataki S. Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter. Cancer Res. 55 (1995) 3105-3109
    • (1995) Cancer Res. , vol.55 , pp. 3105-3109
    • Ido, A.1    Nakata, K.2    Kato, Y.3    Nakao, K.4    Murata, K.5    Fujita, M.6    Ishii, N.7    Tamaoki, T.8    Shiku, H.9    Nagataki, S.10
  • 59
    • 0030906438 scopus 로고    scopus 로고
    • Preferential radiosensitization of 9L glioma cells transduced with HSV-tk gene by acyclovir
    • Kim S.H., Kim J.H., Kolozsvary A., Brown S.L., and Freytag S.O. Preferential radiosensitization of 9L glioma cells transduced with HSV-tk gene by acyclovir. J. Neurooncol. 33 (1997) 189-194
    • (1997) J. Neurooncol. , vol.33 , pp. 189-194
    • Kim, S.H.1    Kim, J.H.2    Kolozsvary, A.3    Brown, S.L.4    Freytag, S.O.5
  • 64
    • 33847212832 scopus 로고    scopus 로고
    • Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer
    • Freytag S.O., Stricker H., Peabody J., Pegg J., Paielli D., Movsas B., Barton K.N., Brown S.L., Lu M., and Kim J.H. Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer. Mol. Ther. 15 (2007) 636-642
    • (2007) Mol. Ther. , vol.15 , pp. 636-642
    • Freytag, S.O.1    Stricker, H.2    Peabody, J.3    Pegg, J.4    Paielli, D.5    Movsas, B.6    Barton, K.N.7    Brown, S.L.8    Lu, M.9    Kim, J.H.10
  • 65
    • 40949133887 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides as immunotherapy in cancer
    • Jahrsdorfer B., and Weiner G.J. CpG oligodeoxynucleotides as immunotherapy in cancer. Update Cancer Ther. 3 (2008) 27-32
    • (2008) Update Cancer Ther. , vol.3 , pp. 27-32
    • Jahrsdorfer, B.1    Weiner, G.J.2
  • 67
    • 33748146943 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides are potent enhancers of radio- and chemoresponses of murine tumors
    • Mason K.A., Neal R., Hunter N., Ariga H., Ang K., and Milas L. CpG oligodeoxynucleotides are potent enhancers of radio- and chemoresponses of murine tumors. Radiother. Oncol. 80 (2006) 192-198
    • (2006) Radiother. Oncol. , vol.80 , pp. 192-198
    • Mason, K.A.1    Neal, R.2    Hunter, N.3    Ariga, H.4    Ang, K.5    Milas, L.6
  • 69
    • 0035370172 scopus 로고    scopus 로고
    • ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture
    • Tribius S., Pidel A., and Casper D. ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture. Int. J. Radiat. Oncol. Biol. Phys. 50 (2001) 511-523
    • (2001) Int. J. Radiat. Oncol. Biol. Phys. , vol.50 , pp. 511-523
    • Tribius, S.1    Pidel, A.2    Casper, D.3
  • 74
    • 42949122558 scopus 로고    scopus 로고
    • UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer
    • Rass K., and Reichrath J. UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer. Adv. Exp. Med. Biol. 624 (2008) 162-178
    • (2008) Adv. Exp. Med. Biol. , vol.624 , pp. 162-178
    • Rass, K.1    Reichrath, J.2
  • 75
    • 36949024714 scopus 로고    scopus 로고
    • Glioblastoma multiforme: the role of DSB repair between genotype and phenotype
    • Fischer U., and Meese E. Glioblastoma multiforme: the role of DSB repair between genotype and phenotype. Oncogene 26 (2007) 7809-7815
    • (2007) Oncogene , vol.26 , pp. 7809-7815
    • Fischer, U.1    Meese, E.2
  • 76
    • 0345491859 scopus 로고    scopus 로고
    • A genotype of the polymorphic DNA repair gene MGMT is associated with de novo glioblastoma
    • Inoue R., Isono M., Abe M., Abe T., and Kobayashi H. A genotype of the polymorphic DNA repair gene MGMT is associated with de novo glioblastoma. Neurol. Res. 25 (2003) 875-879
    • (2003) Neurol. Res. , vol.25 , pp. 875-879
    • Inoue, R.1    Isono, M.2    Abe, M.3    Abe, T.4    Kobayashi, H.5
  • 77
    • 14744272755 scopus 로고    scopus 로고
    • Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death
    • Chen G.G., Sin F.L., Leung B.C., Ng H.K., and Poon W.S. Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death. J. Cell. Physiol. 203 (2005) 127-132
    • (2005) J. Cell. Physiol. , vol.203 , pp. 127-132
    • Chen, G.G.1    Sin, F.L.2    Leung, B.C.3    Ng, H.K.4    Poon, W.S.5
  • 78
    • 0032054738 scopus 로고    scopus 로고
    • Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin
    • Ruan S., Okcu M.F., Ren J.P., Chiao P., Andreeff M., Levin V., and Zhang W. Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Cancer Res. 58 (1998) 1538-1543
    • (1998) Cancer Res. , vol.58 , pp. 1538-1543
    • Ruan, S.1    Okcu, M.F.2    Ren, J.P.3    Chiao, P.4    Andreeff, M.5    Levin, V.6    Zhang, W.7
  • 79
    • 23344453535 scopus 로고    scopus 로고
    • Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin
    • Ito M., Yamamoto S., Nimura K., Hiraoka K., Tamai K., and Kaneda Y. Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin. J. Gene Med. 7 (2005) 1044-1052
    • (2005) J. Gene Med. , vol.7 , pp. 1044-1052
    • Ito, M.1    Yamamoto, S.2    Nimura, K.3    Hiraoka, K.4    Tamai, K.5    Kaneda, Y.6
  • 80
    • 41449097033 scopus 로고    scopus 로고
    • Down regulation of BRCA2 causes radio-sensitization of human tumor cells in vitro and in vivo
    • Yu D., Sekine E., Fujimori A., Ochiya T., and Okayasu R. Down regulation of BRCA2 causes radio-sensitization of human tumor cells in vitro and in vivo. Cancer Sci. 99 (2008) 810-815
    • (2008) Cancer Sci. , vol.99 , pp. 810-815
    • Yu, D.1    Sekine, E.2    Fujimori, A.3    Ochiya, T.4    Okayasu, R.5
  • 82
    • 0038407413 scopus 로고    scopus 로고
    • Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo
    • Li G.C., He F., Shao X., Urano M., Shen L., Kim D., Borrelli M., Leibel S.A., Gutin P.H., and Ling C.C. Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo. Cancer Res. 63 (2003) 3268-3274
    • (2003) Cancer Res. , vol.63 , pp. 3268-3274
    • Li, G.C.1    He, F.2    Shao, X.3    Urano, M.4    Shen, L.5    Kim, D.6    Borrelli, M.7    Leibel, S.A.8    Gutin, P.H.9    Ling, C.C.10
  • 83
    • 70350622182 scopus 로고    scopus 로고
    • APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells
    • Wang D., Xiang D.B., Yang X.Q., Chen L.S., Li M.X., Zhong Z.Y., and Zhang Y.S. APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells. Lung Cancer (2009)
    • (2009) Lung Cancer
    • Wang, D.1    Xiang, D.B.2    Yang, X.Q.3    Chen, L.S.4    Li, M.X.5    Zhong, Z.Y.6    Zhang, Y.S.7
  • 84
    • 51449094587 scopus 로고    scopus 로고
    • Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo
    • Xiang D.B., Chen Z.T., Wang D., Li M.X., Xie J.Y., Zhang Y.S., Qing Y., Li Z.P., and Xie J. Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo. Cancer Gene Ther. 15 (2008) 625-635
    • (2008) Cancer Gene Ther. , vol.15 , pp. 625-635
    • Xiang, D.B.1    Chen, Z.T.2    Wang, D.3    Li, M.X.4    Xie, J.Y.5    Zhang, Y.S.6    Qing, Y.7    Li, Z.P.8    Xie, J.9
  • 85
    • 33947380240 scopus 로고    scopus 로고
    • Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
    • Ratnam K., and Low J.A. Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology. Clin. Cancer Res. 13 (2007) 1383-1388
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1383-1388
    • Ratnam, K.1    Low, J.A.2
  • 87
    • 24944454988 scopus 로고    scopus 로고
    • Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers
    • Peng Z. Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum. Gene Ther. 16 (2005) 1016-1027
    • (2005) Hum. Gene Ther. , vol.16 , pp. 1016-1027
    • Peng, Z.1
  • 88
    • 0347719614 scopus 로고    scopus 로고
    • Adenoviral p53 gene therapy in squamous cell cancer of the head and neck region
    • Edelman J., and Nemunaitis J. Adenoviral p53 gene therapy in squamous cell cancer of the head and neck region. Curr. Opin. Mol. Ther. 5 (2003) 611-617
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , pp. 611-617
    • Edelman, J.1    Nemunaitis, J.2
  • 89
    • 0345707573 scopus 로고    scopus 로고
    • Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer
    • Kakinuma H., Bergert E.R., Spitzweg C., Cheville J.C., Lieber M.M., and Morris J.C. Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer. Cancer Res. 63 (2003) 7840-7844
    • (2003) Cancer Res. , vol.63 , pp. 7840-7844
    • Kakinuma, H.1    Bergert, E.R.2    Spitzweg, C.3    Cheville, J.C.4    Lieber, M.M.5    Morris, J.C.6
  • 93
    • 34548183510 scopus 로고    scopus 로고
    • CPG-7909 (PF-3512676, ProMune): toll-like receptor-9 agonist in cancer therapy
    • Murad Y.M., Clay T.M., Lyerly H.K., and Morse M.A. CPG-7909 (PF-3512676, ProMune): toll-like receptor-9 agonist in cancer therapy. Expert Opin. Biol. Ther. 7 (2007) 1257-1266
    • (2007) Expert Opin. Biol. Ther. , vol.7 , pp. 1257-1266
    • Murad, Y.M.1    Clay, T.M.2    Lyerly, H.K.3    Morse, M.A.4
  • 94
    • 33846663007 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions
    • He F., Li L., Kim D., Wen B., Deng X., Gutin P.H., Ling C.C., and Li G.C. Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions. Cancer Res. 67 (2007) 634-642
    • (2007) Cancer Res. , vol.67 , pp. 634-642
    • He, F.1    Li, L.2    Kim, D.3    Wen, B.4    Deng, X.5    Gutin, P.H.6    Ling, C.C.7    Li, G.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.