Chromene-based synthetic chalcones as potent antileishmanial agents: Synthesis and biological activity

Chemical Biology and Drug Design

Volumn 75, Issue 6, 2010, Pages 590-596

  Foroumadi, Alireza ^a,b   Emami, Saeed ^c   Sorkhi, Maedeh ^a   Nakhjiri, Maryam ^a   Nazarian, Zohreh ^b   Heydari, Samaneh ^b   Ardestani, Sussan K ^d   Poorrajab, Fatemeh ^d   Shafiee, Abbas ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Antileishmanial activity; Chalcones; Chromene; Leishmania major; Promastigotes

Indexed keywords

1 (2 CHLOROPHENYL) 3 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 1 (2,4 DICHLOROPHENYL) 3 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 1 (3 CHLOROPHENYL) 3 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 1 (4 CHLOROPHENYL) 3 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 1 (6 METHOXY 2H CHROMEN 3 YL) 3 PHENYLPROP 2 EN 1 ONE; 1 (6 METHOXY 2H CHROMEN 3 YL) 3 PHENYLPROPEN 1 ONE DERIVATIVE; 3 (2 CHLOROPHENYL) 1 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 3 (2,4 DICHLOROPHENYL) 1 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 3 (3 CHLOROPHENYL) 1 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 3 (4 CHLOROPHENYL) 1 (6 METHOXY 2H CHROMEN 3 YL)PROP 2 EN 1 ONE; 3 (6 METHOXY 2H CHROMEN 3 YL) 1 PHENYLPROP 2 EN 1 ONE; 3 (6 METHOXY 2H CHROMEN 3 YL) 1 PHENYLPROPEN 1 ONE DERIVATIVE; ANTIFLAGELLATE AGENT; ANTILEISHMANIAL AGENT; MEGLUMINE ANTIMONATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; IN VITRO STUDY; LEISHMANIA MAJOR; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZOPYRANS; CHALCONES; LEISHMANIA MAJOR; MACROPHAGES; MICE;

LEISHMANIA MAJOR;

EID: 77951965087     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00959.x     Document Type: Article

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