Targeting aminopeptidase N (APN/CD13) with cyclic-imide peptidomimetics derivative CIP-13F inhibits the growth of human ovarian carcinoma cells

Cancer Letters

Volumn 292, Issue 2, 2010, Pages 153-162

  Cui, Shu Xiang ^a,b   Qu, Xian Jun ^c   Gao, Zu Hua ^d   Zhang, Yu Sheng ^c   Zhang, Xiao Fan ^c   Zhao, Cui Rong ^c   Xu, Wen Fang ^c   Li, Qian Bin ^c   Han, Jin Xiang ^a  

^a Shandong Medicinal Biotechnology Center   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

^d CALGARY LABORATORY SERVICES   (Canada)

Author keywords

Aminopeptidase N (APN CD13); Apoptosis; CIP 13F; Cyclic imide peptidomimetics; Inhibitory effect; Ovarian carcinoma (OVCA)

Indexed keywords

2 AMINO N [1 [2 (HYDROXYAMINO) 2 OXOETHYL] 2,6 DIOXOPIPERIDIN 3 YL] 3 PHENYLPROPANAMIDE; BESTATIN; CASPASE 3; MICROSOMAL AMINOPEPTIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDOMIMETIC AGENT; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG; 2 AMINO N (1 (2 (HYDROXYAMINO) 2 OXOETHYL) 2,6 DIOXOPIPERIDIN 3 YL) 3 PHENYLPROPANAMIDE; 2-AMINO-N-(1-(2-(HYDROXYAMINO)-2-OXOETHYL)-2,6-DIOXOPIPERIDIN-3-YL)-3-PHENYLPROPANAMIDE; ANTINEOPLASTIC AGENT; CYCLOPEPTIDE; IMIDE; PIPERIDINE DERIVATIVE; PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CANCER CELL CULTURE; CANCER INHIBITION; CELL GROWTH; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; QUANTITATIVE STUDY; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; MOLECULAR MIMICRY; NUDE MOUSE; OVARY TUMOR; PATHOLOGY; TUMOR CELL LINE;

MUS;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL DIVISION; CELL LINE, TUMOR; FEMALE; FLOW CYTOMETRY; HUMANS; IMIDES; MICE; MICE, INBRED BALB C; MICE, NUDE; MODELS, MOLECULAR; MOLECULAR MIMICRY; OVARIAN NEOPLASMS; PEPTIDES, CYCLIC; PIPERIDINES; PROTEASE INHIBITORS;

EID: 77951887856     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.11.021     Document Type: Article

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