메뉴 건너뛰기




Volumn 7, Issue , 2007, Pages

Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

BESTATIN; GELATINASE A; METALLOPROTEINASE; MICROSOMAL AMINOPEPTIDASE; SMALL INTERFERING RNA; TRYPAN BLUE; DRUG DERIVATIVE; LEUCINE;

EID: 35148889105     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-140     Document Type: Article
Times cited : (61)

References (31)
  • 1
    • 0029785894 scopus 로고    scopus 로고
    • Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26)
    • 8863861
    • Stange T Kettmann U Holzhausen HJ: Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26). Acta Histochem 1996, 98:323-331. 8863861
    • (1996) Acta Histochem , vol.98 , pp. 323-331
    • Stange, T.1    Kettmann, U.2    Holzhausen, H.J.3
  • 2
    • 0031885821 scopus 로고    scopus 로고
    • Regulation of the expression of aminopeptidase A, aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 in renal carcinoma cells and renal tubular epithelial cells by cytokines and cAMP-increasing mediators
    • 1904914 9486416 10.1046/j.1365-2249.1998.00513.x
    • Kehlen A Gohring B Langner J Riemann D: Regulation of the expression of aminopeptidase A, aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 in renal carcinoma cells and renal tubular epithelial cells by cytokines and cAMP-increasing mediators. Clin Exp Immunol 1998, 111:435-441. 1904914 9486416 10.1046/j.1365-2249.1998.00513.x
    • (1998) Clin Exp Immunol , vol.111 , pp. 435-441
    • Kehlen, A.1    Gohring, B.2    Langner, J.3    Riemann, D.4
  • 3
    • 0028053036 scopus 로고
    • Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin
    • 501755 7907609 10.1136/jcp.47.1.43
    • Dixon J Kaklamanis L Turley H Hickson ID Leek RD Harris AL Gatter KC: Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. J Clin Pathol 1994, 47:43-47. 501755 7907609 10.1136/jcp.47.1.43
    • (1994) J Clin Pathol , vol.47 , pp. 43-47
    • Dixon, J.1    Kaklamanis, L.2    Turley, H.3    Hickson, I.D.4    Leek, R.D.5    Harris, A.L.6    Gatter, K.C.7
  • 4
    • 0027244148 scopus 로고
    • Hematopoietic differentiation antigens that are membrane-associated enzymes: Cutting is the key!
    • 8102558
    • Shipp MA Look AT: Hematopoietic differentiation antigens that are membrane-associated enzymes: Cutting is the key! Blood 1993, 82:1052-1070. 8102558
    • (1993) Blood , vol.82 , pp. 1052-1070
    • Shipp, M.A.1    Look, A.T.2
  • 5
    • 0035254206 scopus 로고    scopus 로고
    • CD13/APN is activated by angiogenic signals and is essential for capillary tube formation
    • 10.1182/blood.V97.3.652 11157481
    • Bhagwat SV Lahdenranta J Giordano R Arap W Pasqualini R Shapiro LH: CD13/ APN is activated by angiogenic signals and is essential for capillary tube formation. Blood 2001, 97:652-659. 10.1182/blood.V97.3.652 11157481
    • (2001) Blood , vol.97 , pp. 652-659
    • Bhagwat, S.V.1    Lahdenranta, J.2    Giordano, R.3    Arap, W.4    Pasqualini, R.5    Shapiro, L.H.6
  • 6
    • 0033082368 scopus 로고    scopus 로고
    • CD13--not just a marker in leukemia typing
    • 10.1016/S0167-5699(98)01398-X 10098327
    • Riemann D Kehlen A Langner J: CD13--not just a marker in leukemia typing. Immunol Today 1999, 20:83-88. 10.1016/S0167-5699(98)01398-X 10098327
    • (1999) Immunol Today , vol.20 , pp. 83-88
    • Riemann, D.1    Kehlen, A.2    Langner, J.3
  • 7
    • 0034992631 scopus 로고    scopus 로고
    • Increased expression of interleukin-8 and aminopeptidase N by cell-cell contact: Interleukin-8 is resistant to degradation by aminopeptidase N/ CD13
    • 11399521
    • Kehlen A Egbert I Thiele K Fischer K Riemann D Langner J: Increased expression of interleukin-8 and aminopeptidase N by cell-cell contact: interleukin-8 is resistant to degradation by aminopeptidase N/CD13. Eur Cytokine Netw 2001, 12:316-324. 11399521
    • (2001) Eur Cytokine Netw , vol.12 , pp. 316-324
    • Kehlen, A.1    Egbert, I.2    Thiele, K.3    Fischer, K.4    Riemann, D.5    Langner, J.6
  • 8
    • 0027195127 scopus 로고
    • Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation
    • 10.1002/ijc.2910540122 8097496
    • Saiki I Fujii H Yoneda J Abe F Nakajima M Tsuruo T Azuma I Role of aminopeptidase N: (CD13) in tumor-cell invasion and extracellular matrix degradation. Int J Cancer 1993, 54:137-143. 10.1002/ijc.2910540122 8097496
    • (1993) Int J Cancer , vol.54 , pp. 137-143
    • Saiki, I.1    Fujii, H.2    Yoneda, J.3    Abe, F.4    Nakajima, M.5    Tsuruo, T.6    Azuma, I.7
  • 9
    • 0036161112 scopus 로고    scopus 로고
    • Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer
    • 10.1053/gast.2002.31095 11832452
    • Hashida H Takabayashi A Kanai M Adachi M Kondo K Kohno N Yamaoka Y Miyake M: Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer. Gastroenterology 2002, 122:376-386. 10.1053/gast.2002.31095 11832452
    • (2002) Gastroenterology , vol.122 , pp. 376-386
    • Hashida, H.1    Takabayashi, A.2    Kanai, M.3    Adachi, M.4    Kondo, K.5    Kohno, N.6    Yamaoka, Y.7    Miyake, M.8
  • 10
    • 0344441775 scopus 로고    scopus 로고
    • Inhibitory effect of antisense aminopeptidase N (APN/CD13) cDNA transfection on the invasive potential of osteosarcoma cells
    • 10.1023/A:1027383729767 14669789
    • Kido A Krueger S Haeckel C Roessner A: Inhibitory effect of antisense aminopeptidase N (APN/CD13) cDNA transfection on the invasive potential of osteosarcoma cells. Clin Exp Metastasis 2003, 20:585-592. 10.1023/ A:1027383729767 14669789
    • (2003) Clin Exp Metastasis , vol.20 , pp. 585-592
    • Kido, A.1    Krueger, S.2    Haeckel, C.3    Roessner, A.4
  • 11
    • 0033763723 scopus 로고    scopus 로고
    • Possible contribution of aminopeptidase N (APN/CD13) to invasive potential enhanced by interleukin-6 and soluble interleukin-6 receptor in human osteosarcoma cell lines
    • 10.1023/A:1006794617406 11089884
    • Kido A Krueger S Haeckel C Roessner A: Possible contribution of aminopeptidase N (APN/CD13) to invasive potential enhanced by interleukin-6 and soluble interleukin-6 receptor in human osteosarcoma cell lines. Clin Exp Metastasis 1999, 17:857-863. 10.1023/ A:1006794617406 11089884
    • (1999) Clin Exp Metastasis , vol.17 , pp. 857-863
    • Kido, A.1    Krueger, S.2    Haeckel, C.3    Roessner, A.4
  • 12
    • 0030879306 scopus 로고    scopus 로고
    • Antisense-mediated inhibition of aminopeptidase N (CD13) markedly decreases growth rates of hematopoietic tumour cells
    • 9330681
    • Wex T Lendeckel U Reinhold D Kahne T Arndt M Frank K Ansorge S: Antisense-mediated inhibition of aminopeptidase N (CD13) markedly decreases growth rates of hematopoietic tumour cells. Adv Exp Med Biol 1997, 421:67-73. 9330681
    • (1997) Adv Exp Med Biol , vol.421 , pp. 67-73
    • Wex, T.1    Lendeckel, U.2    Reinhold, D.3    Kahne, T.4    Arndt, M.5    Frank, K.6    Ansorge, S.7
  • 13
    • 0036468937 scopus 로고    scopus 로고
    • Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
    • 11830545
    • Curnis F Arrigoni G Sacchi A Fischetti L Arap W Pasqualini R Corti A: Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells. Cancer Res 2002, 62:867-874. 11830545
    • (2002) Cancer Res , vol.62 , pp. 867-874
    • Curnis, F.1    Arrigoni, G.2    Sacchi, A.3    Fischetti, L.4    Arap, W.5    Pasqualini, R.6    Corti, A.7
  • 16
    • 0033932187 scopus 로고    scopus 로고
    • Long-term results and prognostic factors in patients with epithelial ovarian cancer
    • 10.1006/gyno.2000.5805 10873404
    • Brun JL Feyler A Chene G Saurel J Brun G Hocke C: Long-term results and prognostic factors in patients with epithelial ovarian cancer. Gynecol Oncol 2000, 78:21-27. 10.1006/gyno.2000.5805 10873404
    • (2000) Gynecol Oncol , vol.78 , pp. 21-27
    • Brun, J.L.1    Feyler, A.2    Chene, G.3    Saurel, J.4    Brun, G.5    Hocke, C.6
  • 17
    • 0033652975 scopus 로고    scopus 로고
    • Randomized trial of cisplatin and carboplatin versus cisplatin, vinblastine and bleomycin in ovarian cancer
    • 10.1159/000010330 11093052
    • Kikkawa F Matsuzawa K Arii Y Kawai M Kobayashi I Nakashima N Mizutani S: Randomized trial of cisplatin and carboplatin versus cisplatin, vinblastine and bleomycin in ovarian cancer. Gynecol Obstet Invest 2000, 50:269-274. 10.1159/000010330 11093052
    • (2000) Gynecol Obstet Invest , vol.50 , pp. 269-274
    • Kikkawa, F.1    Matsuzawa, K.2    Arii, Y.3    Kawai, M.4    Kobayashi, I.5    Nakashima, N.6    Mizutani, S.7
  • 18
    • 23144458515 scopus 로고    scopus 로고
    • Changes in placental dipeptidyl peptidase IV in preeclampsia with intrauterine growth restriction
    • 10.1055/s-2005-870229 16034711
    • Nishikawa M Itakura A Ito M Takeuchi M Sato Y Kajiyama H Mizutani S Kikkawa F: Changes in placental dipeptidyl peptidase IV in preeclampsia with intrauterine growth restriction. Horm Metab Res 2005, 37:408-413. 10.1055/s-2005-870229 16034711
    • (2005) Horm Metab Res , vol.37 , pp. 408-413
    • Nishikawa, M.1    Itakura, A.2    Ito, M.3    Takeuchi, M.4    Sato, Y.5    Kajiyama, H.6    Mizutani, S.7    Kikkawa, F.8
  • 19
    • 0037093198 scopus 로고    scopus 로고
    • Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma
    • 12019149
    • Kajiyama H Kikkawa F Suzuki T Shibata K Ino K Mizutani S: Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma. Cancer Res 2002, 62:2753-2757. 12019149
    • (2002) Cancer Res , vol.62 , pp. 2753-2757
    • Kajiyama, H.1    Kikkawa, F.2    Suzuki, T.3    Shibata, K.4    Ino, K.5    Mizutani, S.6
  • 21
    • 0037372507 scopus 로고    scopus 로고
    • The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis
    • 10.1182/blood-2002-05-1422 12406907
    • Bhagwat SV Petrovic N Okamoto Y Shapiro LH: The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis. Blood 2003, 101:1818-1826. 10.1182/ blood-2002-05-1422 12406907
    • (2003) Blood , vol.101 , pp. 1818-1826
    • Bhagwat, S.V.1    Petrovic, N.2    Okamoto, Y.3    Shapiro, L.H.4
  • 22
    • 1542782212 scopus 로고    scopus 로고
    • CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells
    • 10.1074/jbc.M308071200 14507917
    • Petrovic N Bhagwat SV Ratzan WJ Ostrowski MC Shapiro LH: CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells. J Biol Chem 2003, 278:49358-49368. 10.1074/jbc.M308071200 14507917
    • (2003) J Biol Chem , vol.278 , pp. 49358-49368
    • Petrovic, N.1    Bhagwat, S.V.2    Ratzan, W.J.3    Ostrowski, M.C.4    Shapiro, L.H.5
  • 23
    • 0347626098 scopus 로고    scopus 로고
    • Biological significance of aminopeptidase N/CD13 in thyroid carcinomas
    • 14679016
    • Kehlen A Lendeckel U Dralle H Langner J Hoang-Vu C: Biological significance of aminopeptidase N/CD13 in thyroid carcinomas. Cancer Res 2003, 63:8500-8506. 14679016
    • (2003) Cancer Res , vol.63 , pp. 8500-8506
    • Kehlen, A.1    Lendeckel, U.2    Dralle, H.3    Langner, J.4    Hoang-Vu, C.5
  • 25
    • 0035041649 scopus 로고    scopus 로고
    • Bestatin as an experimental tool in mammals
    • 10.2174/1389200013338748 11465152
    • Scornik OA Botbol V: Bestatin as an experimental tool in mammals. Curr Drug Metab 2001, 2:67-85. 10.2174/1389200013338748 11465152
    • (2001) Curr Drug Metab , vol.2 , pp. 67-85
    • Scornik, O.A.1    Botbol, V.2
  • 26
    • 0033161643 scopus 로고    scopus 로고
    • Role of alanyl aminopeptidase in growth and function of human T cells (review)
    • 10373632
    • Lendeckel U Arndt M Frank K Wex T Ansorge S: Role of alanyl aminopeptidase in growth and function of human T cells (review). Int J Mol Med 1999, 4:17-27. 10373632
    • (1999) Int J Mol Med , vol.4 , pp. 17-27
    • Lendeckel, U.1    Arndt, M.2    Frank, K.3    Wex, T.4    Ansorge, S.5
  • 27
    • 22044454982 scopus 로고    scopus 로고
    • CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells
    • 10.1002/ijc.21089 15812828
    • Chang YW Chen SC Cheng EC Ko YP Lin YC Kao YR Tsay YG Yang PC Wu CW Roffler SR: CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. Int J Cancer 2005, 116:243-252. 10.1002/ijc.21089 15812828
    • (2005) Int J Cancer , vol.116 , pp. 243-252
    • Chang, Y.W.1    Chen, S.C.2    Cheng, E.C.3    Ko, Y.P.4    Lin, Y.C.5    Kao, Y.R.6    Tsay, Y.G.7    Yang, P.C.8    Wu, C.W.9    Roffler, S.R.10
  • 28
    • 1042266693 scopus 로고    scopus 로고
    • Reduced growth, increased vascular area, and reduced response to cisplatin in CD13-overexpressing human ovarian cancer xenografts
    • 10.1158/1078-0432.CCR-0482-3 14871998
    • van Hensbergen Y Broxterman HJ Rana S van Diest PJ Duyndam MC Hoekman K Pinedo HM Boven E: Reduced growth, increased vascular area, and reduced response to cisplatin in CD13-overexpressing human ovarian cancer xenografts. Clin Cancer Res 2004, 10:1180-1191. 10.1158/ 1078-0432.CCR-0482-3 14871998
    • (2004) Clin Cancer Res , vol.10 , pp. 1180-1191
    • van Hensbergen, Y.1    Broxterman, H.J.2    Rana, S.3    van Diest, P.J.4    Duyndam, M.C.5    Hoekman, K.6    Pinedo, H.M.7    Boven, E.8
  • 31
    • 0038364080 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled trial of bestatin in patients with resected stage I squamous-cell lung carcinoma
    • 12697853
    • Ichinose Y Genka K Koike T Kato H Watanabe Y Mori T Iioka S Sakuma A Ohta M: Randomized double-blind placebo-controlled trial of bestatin in patients with resected stage I squamous-cell lung carcinoma. J Natl Cancer Inst 2003, 95:605-610. 12697853
    • (2003) J Natl Cancer Inst , vol.95 , pp. 605-610
    • Ichinose, Y.1    Genka, K.2    Koike, T.3    Kato, H.4    Watanabe, Y.5    Mori, T.6    Iioka, S.7    Sakuma, A.8    Ohta, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.