Leukemic cell-surface CD13/aminopeptidase N and resistance to apoptosis mediated by endothelial cells

Journal of the National Cancer Institute

Volumn 94, Issue 13, 2002, Pages 1020-1028

  Mishima, Yuji ^a   Matsumoto Mishima, Yuko ^b   Terui, Yasuhito ^c   Katsuyama, Misa ^b   Yamada, Muneo ^a   Mori, Masaki ^d   Ishizaka, Yukihito ^e   Ikeda, Kazuma ^f   Watanabe, Jun Ichiro ^b   Mizunuma, Nobuyuki ^b   Hayasawa, Hirotoshi ^a   Hatake, Kiyohiko ^b  

^a MORINAGA MILK INDUSTRY CO LTD   (Japan)

^b CANCER CHEMOTHERAPY CENTER   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

^d JICHI MEDICAL UNIVERSITY   (Japan)

^e NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^f OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BESTATIN; INTERLEUKIN 8; MESSENGER RNA; MICROSOMAL AMINOPEPTIDASE;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL SURFACE; COCULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMIA CELL LINE; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; VASCULAR ENDOTHELIUM;

EID: 0037014744     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/94.13.1020     Document Type: Article

References (39)

1. Activated endothelial cells induce apoptosis in leukemic cells by endothelial interleukin-8
2. Identification of a novel apoptosis-inducing factor derived from leukemic cells: Endothelial interleukin-8, but not monocyte-derived, induces apoptosis in leukemic cells
3. NH2-terminal pentapeptide of endothelial interleukin 8 is responsible for the induction of apoptosis in leukemic cells and has an antitumor effect in vivo
4. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)
5. Hematopoietic differentiation antigens that are membrane-associated enzymes: Cutting is the key!
6. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N
7. Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: Up- and down-regulation of CD13/aminopeptidase N
8. Transforming growth factor-beta increases the expression of aminopeptidase N/CD13 mRNA and protein in monocytes and monocytic cell lines
9. CD13/N-aminopeptidase is involved in the development of dendritic cells and macrophages from cord blood CD34(+) cells
10. Requirement for surface aminopeptidase activities during development of CD8+ fetal thymocytes
11. Dipeptidyl peptidase IV (CD 26) and aminopeptidase N (CD 13) catalyzed hydrolysis of cytokines and peptides with N-terminal cytokine sequences
12. Enkephalin metabolism by microglial aminopeptidase N (CD13)
13. Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: Predominant role of angiotensin III in the control of vasopressin release
14. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
15. Apoptosis during HL-60 cell differentiation is closely related to a G0/G1 cell cycle arrest
16. A new type of major aminopeptidase in bovine brain
17. Isolation and immunocytochemical characterization of human bone marrow stromal macrophages in hemopoietic clusters
18. Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay
19. Programmed cell death: Apoptosis and oncogenesis
20. Expression of Src-like adapter protein mRNA is induced by all-trans retinoic acid
21. Expression of MY7 antigen on myeloid precursor cells
22. Proliferation and differentiation of myelodysplastic CD34+ cells: Phenotypic subpopulations of marrow CD34+ cells
23. Classification of acute myeloid leukemias-a comparison of FAB and immunophenotyping
24. Stromal cell-mediated transcriptional regulation of the CD13/aminopeptidase N gene in leukemic cells
25. Induction of apoptosis by bestatin (ubenimex) in human leukemic cell lines
26. CD13-not just a marker in leukemia typing
27. Induction of the membrane alanyl aminopeptidase gene and surface expression in human T-cells by mitogenic activation
28. Antitumor activity of actinonin in vitro and in vivo
29. Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to gamma-interferon and tumor necrosis factor-alpha
30. Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis
31. Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
32. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
33. Tumor invasion, proteolysis, and angiogenesis
34. Matrix metalloproteinases: Biologic activity and clinical implications
35. CD13/APN is activated by angiogenic signals and is essential for capillary tube formation
36. Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer
37. Immunotherapy with bestatin for acute nonlymphocytic leukemia in adults
38. A randomized phase III study comparing Ubenimex (Bestatin) versus placebo as postoperative adjuvant treatment in patients with stage I squamous cell lung cancer
39. Review of ubenimex (Bestatin): Clinical research