CD8+ NK cells are predominant in chimpanzees, characterized by high NCR expression and cytokine production, and preserved in chronic HIV-1 infection

European Journal of Immunology

Volumn 40, Issue 5, 2010, Pages 1440-1450

  Rutjens, Erik ^a,g,h   Mazza, Stefania ^b,c   Biassoni, Roberto ^d   Koopman, Gerrit ^a   Ugolotti, Elisabetta ^d   Fogli, Manuela ^d   Dubbes, Rob ^a   Costa, Paola ^b,d   Mingari, Maria C ^c,e   Greenwood, Edward J D ^f   Moretta, Lorenzo ^b,c,d   Demaria, Andrea ^b,c,e   Heeney, Jonathan L ^a,f  

^a BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^b Centro di Eccellenza per la Ricerca Biomedica   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d G GASLINI INSTITUTE   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g PharmaCell BV   (Netherlands)

^h NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Chimpanzee; HIV; Natural cytotoxicity receptors (NCR); NK cell

Indexed keywords

CD16 ANTIGEN; CD3 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; HLA DR3 ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL POPULATION; CHIMPANZEE; CYTOKINE PRODUCTION; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; MOUSE; NATURAL KILLER T CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD56; ANTIGENS, CD8; CELLS, CULTURED; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOPHENOTYPING; INTERFERON-GAMMA; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; PAN TROGLODYTES; RECEPTORS, NATURAL KILLER CELL; UP-REGULATION;

EID: 77951742350     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940062     Document Type: Article

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