Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP levels

PLoS Genetics

Volumn 5, Issue 10, 2009, Pages

  Tang, Hei Man Vincent ^a   Siu, Kam Leung ^a   Wong, Chi Ming ^a   Jin, Dong Yan ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; CHECKPOINT KINASE 2; DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; PEROXIREDOXIN; PROTEIN RAD9; REACTIVE OXYGEN METABOLITE; RNA; UNCLASSIFIED DRUG; YEAST PEROXIREDOXIN TSA1P; NUCLEOTIDE; PEROXIDASE; SACCHAROMYCES CEREVISIAE PROTEIN; TSA1 PROTEIN, S CEREVISIAE;

ARTICLE; CELL MUTANT; DNA DAMAGE; FUNGAL STRAIN; GENE DELETION; GENE INTERACTION; GENE OVEREXPRESSION; GENETICS; GENOMIC INSTABILITY; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLASMID; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SITE DIRECTED MUTAGENESIS; STEADY STATE; YEAST; DNA REPAIR; METABOLISM; MUTATION; SACCHAROMYCES CEREVISIAE;

DNA DAMAGE; DNA REPAIR; GENOMIC INSTABILITY; MUTATION; NUCLEOTIDES; PEROXIDASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 73449116050     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000697     Document Type: Article

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