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Volumn 4, Issue , 2010, Pages

Dynamics and Control of the Central Carbon Metabolism in Hepatoma Cells

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGEN; PHOSPHATE;

EID: 77951531555     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-4-54     Document Type: Article
Times cited : (34)

References (89)
  • 1
    • 42949164125 scopus 로고    scopus 로고
    • Formulating genome-scale kinetic models in the post-genome era
    • 10.1038/msb.2008.8, 2290940, 18319723
    • Jamshidi N, Palsson BO. Formulating genome-scale kinetic models in the post-genome era. Mol Syst Biol 2008, 4:171. 10.1038/msb.2008.8, 2290940, 18319723.
    • (2008) Mol Syst Biol , vol.4 , pp. 171
    • Jamshidi, N.1    Palsson, B.O.2
  • 2
    • 67650660306 scopus 로고    scopus 로고
    • Towards the engineering of in vitro systems
    • Hold C, Panke S. Towards the engineering of in vitro systems. J R Soc Interface 2009, 6:507-521.
    • (2009) J R Soc Interface , vol.6 , pp. 507-521
    • Hold, C.1    Panke, S.2
  • 3
    • 0037837641 scopus 로고    scopus 로고
    • Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma
    • 10.1016/S1096-7176(02)00011-3, 12749840
    • Chan C, Berthiaume F, Lee K, Yarmush ML. Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma. Metab Eng 2003, 5:1-15. 10.1016/S1096-7176(02)00011-3, 12749840.
    • (2003) Metab Eng , vol.5 , pp. 1-15
    • Chan, C.1    Berthiaume, F.2    Lee, K.3    Yarmush, M.L.4
  • 4
    • 0032788488 scopus 로고    scopus 로고
    • Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver
    • 10.1097/00004630-199907000-00004, 10425591
    • Yarmush DM, MacDonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML. Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver. J Burn Care Rehabil 1999, 20:292-302. 10.1097/00004630-199907000-00004, 10425591.
    • (1999) J Burn Care Rehabil , vol.20 , pp. 292-302
    • Yarmush, D.M.1    MacDonald, A.D.2    Foy, B.D.3    Berthiaume, F.4    Tompkins, R.G.5    Yarmush, M.L.6
  • 5
    • 0038711281 scopus 로고    scopus 로고
    • Profiling of dynamic changes in hypermetabolic livers
    • 10.1002/bit.10682, 12800135
    • Lee K, Berthiaume F, Stephanopoulos GN, Yarmush ML. Profiling of dynamic changes in hypermetabolic livers. Biotechnol Bioeng 2003, 83:400-415. 10.1002/bit.10682, 12800135.
    • (2003) Biotechnol Bioeng , vol.83 , pp. 400-415
    • Lee, K.1    Berthiaume, F.2    Stephanopoulos, G.N.3    Yarmush, M.L.4
  • 6
    • 44449113808 scopus 로고    scopus 로고
    • Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part I. Experimental observations
    • 10.1002/bit.21747, 18095337
    • Hofmann U, Maier K, Niebel A, Vacun G, Reuss M, Mauch K. Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part I. Experimental observations. Biotechnol Bioeng 2008, 100:344-354. 10.1002/bit.21747, 18095337.
    • (2008) Biotechnol Bioeng , vol.100 , pp. 344-354
    • Hofmann, U.1    Maier, K.2    Niebel, A.3    Vacun, G.4    Reuss, M.5    Mauch, K.6
  • 7
    • 44449177159 scopus 로고    scopus 로고
    • Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part II. Flux estimation
    • 10.1002/bit.21746, 18095336
    • Maier K, Hofmann U, Reuss M, Mauch K. Identification of metabolic fluxes in hepatic cells from transient 13C-labeling experiments: Part II. Flux estimation. Biotechnol Bioeng 2008, 100:355-370. 10.1002/bit.21746, 18095336.
    • (2008) Biotechnol Bioeng , vol.100 , pp. 355-370
    • Maier, K.1    Hofmann, U.2    Reuss, M.3    Mauch, K.4
  • 8
    • 0033179481 scopus 로고    scopus 로고
    • Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
    • 10.1046/j.1432-1327.1999.00534.x, 10469130
    • Ainscow EK, Brand MD. Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 1999, 263:671-685. 10.1046/j.1432-1327.1999.00534.x, 10469130.
    • (1999) Eur J Biochem , vol.263 , pp. 671-685
    • Ainscow, E.K.1    Brand, M.D.2
  • 10
    • 0026783260 scopus 로고
    • Control Analysis of Rat-Liver Glycolysis under Different Glucose-Concentrations - the Substrate Approach and the Role of Glucokinase
    • Melendezhevia E, Mateo F, Torres NV. Control Analysis of Rat-Liver Glycolysis under Different Glucose-Concentrations - the Substrate Approach and the Role of Glucokinase. Molecular and Cellular Biochemistry 1992, 115:1-9.
    • (1992) Molecular and Cellular Biochemistry , vol.115 , pp. 1-9
    • Melendezhevia, E.1    Mateo, F.2    Torres, N.V.3
  • 11
    • 0022499217 scopus 로고
    • Kinetics of Metabolic Pathways - a System Invitro to Study the Control of Flux
    • 1146541, 3707539
    • Torres NV, Mateo F, Melendezhevia E, Kacser H. Kinetics of Metabolic Pathways - a System Invitro to Study the Control of Flux. Biochemical Journal 1986, 234:169-174. 1146541, 3707539.
    • (1986) Biochemical Journal , vol.234 , pp. 169-174
    • Torres, N.V.1    Mateo, F.2    Melendezhevia, E.3    Kacser, H.4
  • 12
    • 0343907200 scopus 로고    scopus 로고
    • In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae 2. Mathematical model
    • 10.1002/(SICI)1097-0290(19970820)55:4<592::AID-BIT2>3.0.CO;2-C, 18636570
    • Rizzi M, Baltes M, Theobald U, Reuss M. In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae 2. Mathematical model. Biotechnol Bioeng 1997, 55:592-608. 10.1002/(SICI)1097-0290(19970820)55:4<592::AID-BIT2>3.0.CO;2-C, 18636570.
    • (1997) Biotechnol Bioeng , vol.55 , pp. 592-608
    • Rizzi, M.1    Baltes, M.2    Theobald, U.3    Reuss, M.4
  • 13
    • 33747171718 scopus 로고    scopus 로고
    • Monitoring and modeling of the reaction dynamics in the valine/leucine synthesis pathway in Corynebacterium glutamicum
    • Magnus JB, Hollwedel D, Oldiges M, Takors R. Monitoring and modeling of the reaction dynamics in the valine/leucine synthesis pathway in Corynebacterium glutamicum. Biotechnol Progr 2006, 22:1071-1083.
    • (2006) Biotechnol Progr , vol.22 , pp. 1071-1083
    • Magnus, J.B.1    Hollwedel, D.2    Oldiges, M.3    Takors, R.4
  • 14
    • 63649141014 scopus 로고    scopus 로고
    • Modeling metabolic networks in C. glutamicum: a comparison of rate laws in combination with various parameter optimization strategies
    • 10.1186/1752-0509-3-5, 2661887, 19144170
    • Dräger A, Kronfeld M, Ziller MJ, Supper J, Planatscher H, Magnus JB, Oldiges M, Kohlbacher O, Zell A. Modeling metabolic networks in C. glutamicum: a comparison of rate laws in combination with various parameter optimization strategies. Bmc Systems Biology 2009, 3:5. 10.1186/1752-0509-3-5, 2661887, 19144170.
    • (2009) Bmc Systems Biology , vol.3 , pp. 5
    • Dräger, A.1    Kronfeld, M.2    Ziller, M.J.3    Supper, J.4    Planatscher, H.5    Magnus, J.B.6    Oldiges, M.7    Kohlbacher, O.8    Zell, A.9
  • 17
    • 0025165019 scopus 로고
    • Hep-G2 Cells as a Resource for Metabolic Studies - Lipoprotein, Cholesterol, and Bile-Acids
    • Javitt NB. Hep-G2 Cells as a Resource for Metabolic Studies - Lipoprotein, Cholesterol, and Bile-Acids. Faseb Journal 1990, 4:161-168.
    • (1990) Faseb Journal , vol.4 , pp. 161-168
    • Javitt, N.B.1
  • 19
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • 10.1126/science.6248960, 6248960
    • Knowles BB, Howe CC, Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 1980, 209:497-499. 10.1126/science.6248960, 6248960.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 21
    • 0037025146 scopus 로고    scopus 로고
    • Dynamic Modeling of the Central Carbon Metabolism of Escherichia Coli
    • 10.1002/bit.10288, 17590932
    • Chassagnole C, Noisommit-Rizzi N, Schmid JW, Mauch K, Reuss M. Dynamic Modeling of the Central Carbon Metabolism of Escherichia Coli. Biotechnol Bioeng 2002, 79:53-73. 10.1002/bit.10288, 17590932.
    • (2002) Biotechnol Bioeng , vol.79 , pp. 53-73
    • Chassagnole, C.1    Noisommit-Rizzi, N.2    Schmid, J.W.3    Mauch, K.4    Reuss, M.5
  • 22
    • 33846849309 scopus 로고    scopus 로고
    • A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics
    • 10.1186/1471-2105-7-540, 1781081, 17184531
    • Nikerel IE, van Winden WA, van Gulik WM, Heijnen JJ. A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics. BMC Bioinformatics 2006, 7:540. 10.1186/1471-2105-7-540, 1781081, 17184531.
    • (2006) BMC Bioinformatics , vol.7 , pp. 540
    • Nikerel, I.E.1    van Winden, W.A.2    van Gulik, W.M.3    Heijnen, J.J.4
  • 24
    • 33947503169 scopus 로고    scopus 로고
    • Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry
    • 10.1016/j.chroma.2007.02.034, 17376459
    • Luo B, Groenke K, Takors R, Wandrey C, Oldiges M. Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry. Journal of Chromatography A 2007, 1147:153-164. 10.1016/j.chroma.2007.02.034, 17376459.
    • (2007) Journal of Chromatography A , vol.1147 , pp. 153-164
    • Luo, B.1    Groenke, K.2    Takors, R.3    Wandrey, C.4    Oldiges, M.5
  • 25
    • 62249146094 scopus 로고    scopus 로고
    • In Vivo Dynamics of Glycolysis in Escherichia coli Shows Need for Growth-Rate Dependent Metabolome Analysis
    • Schaub J, Reuss M. In Vivo Dynamics of Glycolysis in Escherichia coli Shows Need for Growth-Rate Dependent Metabolome Analysis. Biotechnol Progr 2008, 24:1402-1407.
    • (2008) Biotechnol Progr , vol.24 , pp. 1402-1407
    • Schaub, J.1    Reuss, M.2
  • 26
    • 0343471961 scopus 로고    scopus 로고
    • In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae 1. Experimental observations
    • 10.1002/(SICI)1097-0290(19970720)55:2<305::AID-BIT8>3.0.CO;2-M, 18636489
    • Theobald U, Mailinger W, Baltes M, Rizzi M, Reuss M. In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae 1. Experimental observations. Biotechnol Bioeng 1997, 55:305-316. 10.1002/(SICI)1097-0290(19970720)55:2<305::AID-BIT8>3.0.CO;2-M, 18636489.
    • (1997) Biotechnol Bioeng , vol.55 , pp. 305-316
    • Theobald, U.1    Mailinger, W.2    Baltes, M.3    Rizzi, M.4    Reuss, M.5
  • 27
    • 15244351549 scopus 로고    scopus 로고
    • Determination of elasticities, concentration and flux control coefficients from transient metabolite data using linlog kinetics
    • 10.1016/j.ymben.2004.12.002, 15781422
    • Kresnowati MT, van Winden WA, Heijnen JJ. Determination of elasticities, concentration and flux control coefficients from transient metabolite data using linlog kinetics. Metab Eng 2005, 7:142-153. 10.1016/j.ymben.2004.12.002, 15781422.
    • (2005) Metab Eng , vol.7 , pp. 142-153
    • Kresnowati, M.T.1    van Winden, W.A.2    Heijnen, J.J.3
  • 28
    • 0015989446 scopus 로고
    • A linear steady-state treatment of enzymatic chains. General properties, control and effector strength
    • 10.1111/j.1432-1033.1974.tb03318.x, 4830198
    • Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. Eur J Biochem 1974, 42:89-95. 10.1111/j.1432-1033.1974.tb03318.x, 4830198.
    • (1974) Eur J Biochem , vol.42 , pp. 89-95
    • Heinrich, R.1    Rapoport, T.A.2
  • 31
    • 0036526636 scopus 로고    scopus 로고
    • The mathematics of metabolic control analysis revisited
    • 10.1006/mben.2001.0216, 12009791
    • Visser D, Heijnen JJ. The mathematics of metabolic control analysis revisited. Metab Eng 2002, 4:114-123. 10.1006/mben.2001.0216, 12009791.
    • (2002) Metab Eng , vol.4 , pp. 114-123
    • Visser, D.1    Heijnen, J.J.2
  • 32
    • 0033573156 scopus 로고    scopus 로고
    • Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
    • 10.1046/j.1432-1327.1999.00856.x, 10583367
    • Ainscow EK, Brand MD. Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 1999, 266:737-749. 10.1046/j.1432-1327.1999.00856.x, 10583367.
    • (1999) Eur J Biochem , vol.266 , pp. 737-749
    • Ainscow, E.K.1    Brand, M.D.2
  • 33
    • 0033231404 scopus 로고    scopus 로고
    • The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis
    • 10.1046/j.1432-1327.1999.00820.x, 10518800
    • Ainscow EK, Brand MD. The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis. Eur J Biochem 1999, 265:1043-1055. 10.1046/j.1432-1327.1999.00820.x, 10518800.
    • (1999) Eur J Biochem , vol.265 , pp. 1043-1055
    • Ainscow, E.K.1    Brand, M.D.2
  • 34
    • 0032524049 scopus 로고    scopus 로고
    • Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis
    • 10.1046/j.1432-1327.1998.2540194.x, 9652414
    • Soboll S, Oh MH, Brown GC. Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis. Eur J Biochem 1998, 254:194-201. 10.1046/j.1432-1327.1998.2540194.x, 9652414.
    • (1998) Eur J Biochem , vol.254 , pp. 194-201
    • Soboll, S.1    Oh, M.H.2    Brown, G.C.3
  • 35
    • 0035968302 scopus 로고    scopus 로고
    • Hepatic glycogen synthesis is highly sensitive to phosphorylase activity - Evidence from metabolic control analysis
    • 10.1074/jbc.M101454200, 11309391
    • Aiston S, Hampson L, Gomez-Foix AM, Guinovart JJ, Agius L. Hepatic glycogen synthesis is highly sensitive to phosphorylase activity - Evidence from metabolic control analysis. Journal of Biological Chemistry 2001, 276:23858-23866. 10.1074/jbc.M101454200, 11309391.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 23858-23866
    • Aiston, S.1    Hampson, L.2    Gomez-Foix, A.M.3    Guinovart, J.J.4    Agius, L.5
  • 36
    • 0022877497 scopus 로고
    • Control of Gluconeogenesis in Rat-Liver Cells - Flux Control Coefficients of the Enzymes in the Gluconeogenic Pathway in the Absence and Presence of Glucagon
    • 1146997, 3800895
    • Groen AK, Vanroermund CWT, Vervoorn RC, Tager JM. Control of Gluconeogenesis in Rat-Liver Cells - Flux Control Coefficients of the Enzymes in the Gluconeogenic Pathway in the Absence and Presence of Glucagon. Biochemical Journal 1986, 237:379-389. 1146997, 3800895.
    • (1986) Biochemical Journal , vol.237 , pp. 379-389
    • Groen, A.K.1    Vanroermund, C.W.T.2    Vervoorn, R.C.3    Tager, J.M.4
  • 37
    • 0028961539 scopus 로고
    • A model of the pentose phosphate pathway in rat liver cells
    • 10.1007/BF00928908, 7753046
    • Sabate L, Franco R, Canela EI, Centelles JJ, Cascante M. A model of the pentose phosphate pathway in rat liver cells. Mol Cell Biochem 1995, 142:9-17. 10.1007/BF00928908, 7753046.
    • (1995) Mol Cell Biochem , vol.142 , pp. 9-17
    • Sabate, L.1    Franco, R.2    Canela, E.I.3    Centelles, J.J.4    Cascante, M.5
  • 38
    • 25144492110 scopus 로고    scopus 로고
    • Approximative kinetic formats used in metabolic network modeling
    • 10.1002/bit.20558, 16003779
    • Heijnen JJ. Approximative kinetic formats used in metabolic network modeling. Biotechnol Bioeng 2005, 91:534-545. 10.1002/bit.20558, 16003779.
    • (2005) Biotechnol Bioeng , vol.91 , pp. 534-545
    • Heijnen, J.J.1
  • 39
    • 60849105949 scopus 로고    scopus 로고
    • Translating biochemical network models between different kinetic formats
    • 10.1016/j.ymben.2008.10.002, 19013536
    • Hadlich F, Noack S, Wiechert W. Translating biochemical network models between different kinetic formats. Metab Eng 2009, 11:87-100. 10.1016/j.ymben.2008.10.002, 19013536.
    • (2009) Metab Eng , vol.11 , pp. 87-100
    • Hadlich, F.1    Noack, S.2    Wiechert, W.3
  • 40
    • 63449097322 scopus 로고    scopus 로고
    • In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter
    • 10.1002/ijc.24189, 19123483
    • Wu CH, Ho YS, Tsai CY, Wang YJ, Tseng H, Wei PL, Lee CH, Liu RS, Lin SY. In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter. Int J Cancer 2009, 124:2210-2219. 10.1002/ijc.24189, 19123483.
    • (2009) Int J Cancer , vol.124 , pp. 2210-2219
    • Wu, C.H.1    Ho, Y.S.2    Tsai, C.Y.3    Wang, Y.J.4    Tseng, H.5    Wei, P.L.6    Lee, C.H.7    Liu, R.S.8    Lin, S.Y.9
  • 41
    • 0029938022 scopus 로고    scopus 로고
    • Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes
    • Thorens B. Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am J Physiol 1996, 270:541-553.
    • (1996) Am J Physiol , vol.270 , pp. 541-553
    • Thorens, B.1
  • 42
    • 0002872235 scopus 로고
    • Inhibition of phosphoglucose isomerase
    • 10.1038/1781401a0, 13387725
    • Parr CW. Inhibition of phosphoglucose isomerase. Nature 1956, 178:1401. 10.1038/1781401a0, 13387725.
    • (1956) Nature , vol.178 , pp. 1401
    • Parr, C.W.1
  • 43
    • 0024536465 scopus 로고
    • Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo
    • 10.1111/j.1471-4159.1989.tb09178.x, 2709006
    • Gaitonde MK, Murray E, Cunningham VJ. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem 1989, 52:1348-1352. 10.1111/j.1471-4159.1989.tb09178.x, 2709006.
    • (1989) J Neurochem , vol.52 , pp. 1348-1352
    • Gaitonde, M.K.1    Murray, E.2    Cunningham, V.J.3
  • 44
    • 0015240540 scopus 로고
    • Phosphoglucose isomerase from human erythrocyte. Preparation and properties
    • Tsuboi KK, Fukunaga K, Chervenka CH. Phosphoglucose isomerase from human erythrocyte. Preparation and properties. J Biol Chem 1971, 246:7586-7594.
    • (1971) J Biol Chem , vol.246 , pp. 7586-7594
    • Tsuboi, K.K.1    Fukunaga, K.2    Chervenka, C.H.3
  • 45
    • 0033953279 scopus 로고    scopus 로고
    • The use of in situ haemoglobin-free perfused liver in metabolic-control analysis
    • Soboll S, Brown GC. The use of in situ haemoglobin-free perfused liver in metabolic-control analysis. Biochem Soc Trans 2000, 28:109-113.
    • (2000) Biochem Soc Trans , vol.28 , pp. 109-113
    • Soboll, S.1    Brown, G.C.2
  • 47
    • 35448961939 scopus 로고    scopus 로고
    • The Warburg effect and its cancer therapeutic implications
    • 10.1007/s10863-007-9086-x, 17551814
    • Chen Z, Lu W, Garcia-Prieto C, Huang P. The Warburg effect and its cancer therapeutic implications. J Bioenerg Biomembr 2007, 39:267-274. 10.1007/s10863-007-9086-x, 17551814.
    • (2007) J Bioenerg Biomembr , vol.39 , pp. 267-274
    • Chen, Z.1    Lu, W.2    Garcia-Prieto, C.3    Huang, P.4
  • 48
    • 0043029566 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications
    • 10.1038/sj.leu.2403043, 12886229
    • Carew JS, Zhou Y, Albitar M, Carew JD, Keating MJ, Huang P. Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia 2003, 17:1437-1447. 10.1038/sj.leu.2403043, 12886229.
    • (2003) Leukemia , vol.17 , pp. 1437-1447
    • Carew, J.S.1    Zhou, Y.2    Albitar, M.3    Carew, J.D.4    Keating, M.J.5    Huang, P.6
  • 49
    • 44949104134 scopus 로고    scopus 로고
    • Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways
    • 2447884, 18629230
    • Moreno-Sanchez R, Saavedra E, Rodriguez-Enriquez S, Olin-Sandoval V. Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. J Biomed Biotechnol 2008, 2008:597913. 2447884, 18629230.
    • (2008) J Biomed Biotechnol , vol.2008 , pp. 597913
    • Moreno-Sanchez, R.1    Saavedra, E.2    Rodriguez-Enriquez, S.3    Olin-Sandoval, V.4
  • 50
    • 0019132335 scopus 로고
    • Are growth rates of Escherichia coli in batch cultures limited by respiration?
    • 294601, 6998942
    • Andersen KB, von Meyenburg K. Are growth rates of Escherichia coli in batch cultures limited by respiration?. J Bacteriol 1980, 144:114-123. 294601, 6998942.
    • (1980) J Bacteriol , vol.144 , pp. 114-123
    • Andersen, K.B.1    von Meyenburg, K.2
  • 51
    • 0021144978 scopus 로고
    • The respiratory chains of Escherichia coli
    • 373010, 6387427
    • Ingledew WJ, Poole RK. The respiratory chains of Escherichia coli. Microbiol Rev 1984, 48:222-271. 373010, 6387427.
    • (1984) Microbiol Rev , vol.48 , pp. 222-271
    • Ingledew, W.J.1    Poole, R.K.2
  • 52
    • 0014242753 scopus 로고
    • Studies on respiration and glycolysis in transplanted hepatic tumors of the rat
    • Lo C, Cristofalo VJ, Morris HP, Weinhouse S. Studies on respiration and glycolysis in transplanted hepatic tumors of the rat. Cancer Res 1968, 28:1-10.
    • (1968) Cancer Res , vol.28 , pp. 1-10
    • Lo, C.1    Cristofalo, V.J.2    Morris, H.P.3    Weinhouse, S.4
  • 54
    • 43549121719 scopus 로고    scopus 로고
    • The Warburg effect: Why and how do cancer cells activate glycolysis in the presence of oxygen?
    • 10.2174/187152008783961932, 18393789
    • Lopez-Lazaro M. The Warburg effect: Why and how do cancer cells activate glycolysis in the presence of oxygen?. Anti-Cancer Agents in Medicinal Chemistry 2008, 8:305-312. 10.2174/187152008783961932, 18393789.
    • (2008) Anti-Cancer Agents in Medicinal Chemistry , vol.8 , pp. 305-312
    • Lopez-Lazaro, M.1
  • 55
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • 10.1038/sj.onc.1209597, 16892078
    • Pelicano H, Martin DS, Xu RH, Huang P. Glycolysis inhibition for anticancer treatment. Oncogene 2006, 25:4633-4646. 10.1038/sj.onc.1209597, 16892078.
    • (2006) Oncogene , vol.25 , pp. 4633-4646
    • Pelicano, H.1    Martin, D.S.2    Xu, R.H.3    Huang, P.4
  • 56
    • 0015377015 scopus 로고
    • Interrelationship and Control of Glucose-Metabolism and Lipogenesis in Isolated Fat-Cells - Control of Pentose Phosphate Cycle Activity by Cellular Requirement for Reduced Nicotinamide Adenine-Dinucleotide Phosphate
    • 1173996, 4404962
    • Kather H, Rivera M, Brand K. Interrelationship and Control of Glucose-Metabolism and Lipogenesis in Isolated Fat-Cells - Control of Pentose Phosphate Cycle Activity by Cellular Requirement for Reduced Nicotinamide Adenine-Dinucleotide Phosphate. Biochemical Journal 1972, 128:1089-1096. 1173996, 4404962.
    • (1972) Biochemical Journal , vol.128 , pp. 1089-1096
    • Kather, H.1    Rivera, M.2    Brand, K.3
  • 57
    • 0033107539 scopus 로고    scopus 로고
    • In vivo dynamics of the pentose phosphate pathway in Saccharomyces cerevisiae
    • 10.1006/mben.1998.0110, 10935926
    • Vaseghi S, Baumeister A, Rizzi M, Reuss M. In vivo dynamics of the pentose phosphate pathway in Saccharomyces cerevisiae. Metab Eng 1999, 1:128-140. 10.1006/mben.1998.0110, 10935926.
    • (1999) Metab Eng , vol.1 , pp. 128-140
    • Vaseghi, S.1    Baumeister, A.2    Rizzi, M.3    Reuss, M.4
  • 58
    • 0025119821 scopus 로고
    • Characterization of glucose-6-phosphate dehydrogenase isozymes from human and pig brain
    • 10.1016/0306-4522(90)90074-E, 2270145
    • Cho SW, Joshi JG. Characterization of glucose-6-phosphate dehydrogenase isozymes from human and pig brain. Neuroscience 1990, 38:819-828. 10.1016/0306-4522(90)90074-E, 2270145.
    • (1990) Neuroscience , vol.38 , pp. 819-828
    • Cho, S.W.1    Joshi, J.G.2
  • 59
    • 0025007883 scopus 로고
    • Control of Respiration and Oxidative-Phosphorylation in Isolated Rat-Liver Cells
    • 10.1111/j.1432-1033.1990.tb19234.x, 2209591
    • Brown GC, Lakinthomas PL, Brand MD. Control of Respiration and Oxidative-Phosphorylation in Isolated Rat-Liver Cells. Eur J Biochem 1990, 192:355-362. 10.1111/j.1432-1033.1990.tb19234.x, 2209591.
    • (1990) Eur J Biochem , vol.192 , pp. 355-362
    • Brown, G.C.1    Lakinthomas, P.L.2    Brand, M.D.3
  • 60
    • 0021874741 scopus 로고
    • Mathematical modelling of metabolic pathways affected by an enzyme deficiency. A mathematical model of glycolysis in normal and pyruvate-kinase-deficient red blood cells
    • 10.1111/j.1432-1033.1985.tb08899.x, 3996397
    • Holzhütter HG, Jacobasch G, Bisdorff A. Mathematical modelling of metabolic pathways affected by an enzyme deficiency. A mathematical model of glycolysis in normal and pyruvate-kinase-deficient red blood cells. Eur J Biochem 1985, 149:101-111. 10.1111/j.1432-1033.1985.tb08899.x, 3996397.
    • (1985) Eur J Biochem , vol.149 , pp. 101-111
    • Holzhütter, H.G.1    Jacobasch, G.2    Bisdorff, A.3
  • 61
    • 0001787632 scopus 로고
    • Regulatory responses and control analysis: assessment of the relative importance of internal effectors
    • CML: New York: Plenum Press, Cornish-Bowden A
    • Sauro HM. Regulatory responses and control analysis: assessment of the relative importance of internal effectors. Control of Metabolic Processes 1990, 225-230. CML: New York: Plenum Press, Cornish-Bowden A.
    • (1990) Control of Metabolic Processes , pp. 225-230
    • Sauro, H.M.1
  • 62
    • 0027605597 scopus 로고
    • The Regulatory Strength - How to Be Precise About Regulation and Homeostasis
    • 10.1007/BF00712777, 8266748
    • Kahn D, Westerhoff HV. The Regulatory Strength - How to Be Precise About Regulation and Homeostasis. Acta Biotheoretica 1993, 41:85-96. 10.1007/BF00712777, 8266748.
    • (1993) Acta Biotheoretica , vol.41 , pp. 85-96
    • Kahn, D.1    Westerhoff, H.V.2
  • 63
    • 68049129530 scopus 로고    scopus 로고
    • Quantification of statin effects on hepatic cholesterol synthesis by transient (13)C-flux analysis
    • 10.1016/j.ymben.2009.06.001, 19555774
    • Maier K, Hofmann U, Bauer A, Niebel A, Vacun G, Reuss M, Mauch K. Quantification of statin effects on hepatic cholesterol synthesis by transient (13)C-flux analysis. Metab Eng 2009, 11:292-309. 10.1016/j.ymben.2009.06.001, 19555774.
    • (2009) Metab Eng , vol.11 , pp. 292-309
    • Maier, K.1    Hofmann, U.2    Bauer, A.3    Niebel, A.4    Vacun, G.5    Reuss, M.6    Mauch, K.7
  • 64
    • 11144263646 scopus 로고    scopus 로고
    • P/O ratios of mitochondrial oxidative phosphorylation
    • 10.1016/j.bbabio.2004.09.004, 15620362
    • Hinkle PC. P/O ratios of mitochondrial oxidative phosphorylation. Biochim Biophys Acta 2005, 1706:1-11. 10.1016/j.bbabio.2004.09.004, 15620362.
    • (2005) Biochim Biophys Acta , vol.1706 , pp. 1-11
    • Hinkle, P.C.1
  • 65
    • 70349767923 scopus 로고    scopus 로고
    • Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2
    • 10.1016/j.taap.2009.07.005, 19607853
    • Niklas J, Noor F, Heinzle E. Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2. Toxicol Appl Pharmacol 2009, 240:327-336. 10.1016/j.taap.2009.07.005, 19607853.
    • (2009) Toxicol Appl Pharmacol , vol.240 , pp. 327-336
    • Niklas, J.1    Noor, F.2    Heinzle, E.3
  • 66
    • 0036081012 scopus 로고    scopus 로고
    • BRENDA, enzyme data and metabolic information
    • 10.1093/nar/30.1.47, 99121, 11752250
    • Schomburg I, Chang A, Schomburg D. BRENDA, enzyme data and metabolic information. Nucleic Acids Res 2002, 30:47-49. 10.1093/nar/30.1.47, 99121, 11752250.
    • (2002) Nucleic Acids Res , vol.30 , pp. 47-49
    • Schomburg, I.1    Chang, A.2    Schomburg, D.3
  • 67
    • 0001125440 scopus 로고
    • Detecting Strictly Detailed Balanced Subnetworks in Open Chemical-Reaction Networks
    • Schuster S, Schuster R. Detecting Strictly Detailed Balanced Subnetworks in Open Chemical-Reaction Networks. Journal of Mathematical Chemistry 1991, 6:17-40.
    • (1991) Journal of Mathematical Chemistry , vol.6 , pp. 17-40
    • Schuster, S.1    Schuster, R.2
  • 68
    • 77953694934 scopus 로고    scopus 로고
    • Metabolic egineering of the valine pathway in corynebacterium glutamicum: analysis and modelling
    • University of Stuttgart, Institute of Biochemical Engineering
    • Magnus JB. Metabolic egineering of the valine pathway in corynebacterium glutamicum: analysis and modelling. PhD thesis 2008, University of Stuttgart, Institute of Biochemical Engineering.
    • (2008) PhD thesis
    • Magnus, J.B.1
  • 69
    • 0001415147 scopus 로고
    • One Step and Extrapolation Methods for Differential- Algebraic Systems
    • Deuflard P, Hairer E, Zugck J. One Step and Extrapolation Methods for Differential- Algebraic Systems. Numer Math 1987, 51:501-516.
    • (1987) Numer Math , vol.51 , pp. 501-516
    • Deuflard, P.1    Hairer, E.2    Zugck, J.3
  • 70
    • 0141684666 scopus 로고    scopus 로고
    • Dynamic simulation and metabolic re-design of a branched pathway using linlog kinetics
    • 10.1016/S1096-7176(03)00025-9, 12948750
    • Visser D, Heijnen JJ. Dynamic simulation and metabolic re-design of a branched pathway using linlog kinetics. Metab Eng 2003, 5:164-176. 10.1016/S1096-7176(03)00025-9, 12948750.
    • (2003) Metab Eng , vol.5 , pp. 164-176
    • Visser, D.1    Heijnen, J.J.2
  • 71
    • 6044260198 scopus 로고    scopus 로고
    • Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics
    • 10.1016/j.ymben.2004.07.001, 15491866
    • Visser D, Schmid JW, Mauch K, Reuss M, Heijnen JJ. Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics. Metab Eng 2004, 6:378-390. 10.1016/j.ymben.2004.07.001, 15491866.
    • (2004) Metab Eng , vol.6 , pp. 378-390
    • Visser, D.1    Schmid, J.W.2    Mauch, K.3    Reuss, M.4    Heijnen, J.J.5
  • 73
    • 58149156532 scopus 로고    scopus 로고
    • Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws - a promising method for speeding up the kinetic modelling of complex metabolic networks
    • 10.1111/j.1742-4658.2008.06784.x, 19137631
    • Bulik S, Grimbs S, Huthmacher C, Selbig J, Holzhutter HG. Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws - a promising method for speeding up the kinetic modelling of complex metabolic networks. Febs Journal 2009, 276:410-424. 10.1111/j.1742-4658.2008.06784.x, 19137631.
    • (2009) Febs Journal , vol.276 , pp. 410-424
    • Bulik, S.1    Grimbs, S.2    Huthmacher, C.3    Selbig, J.4    Holzhutter, H.G.5
  • 74
    • 0035377566 scopus 로고    scopus 로고
    • Completely derandomized self-adaption in evolutionary strategies
    • 10.1162/106365601750190398, 11382355
    • Hansen N, Ostermeier A. Completely derandomized self-adaption in evolutionary strategies. Evolutionary Computation 2001, 9:159-195. 10.1162/106365601750190398, 11382355.
    • (2001) Evolutionary Computation , vol.9 , pp. 159-195
    • Hansen, N.1    Ostermeier, A.2
  • 76
    • 0037041034 scopus 로고    scopus 로고
    • Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase
    • 10.1074/jbc.M105984200, 11756407
    • Veiga-da-Cunha M, Van Schaftingen E. Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase. J Biol Chem 2002, 277:8466-8473. 10.1074/jbc.M105984200, 11756407.
    • (2002) J Biol Chem , vol.277 , pp. 8466-8473
    • Veiga-da-Cunha, M.1    Van Schaftingen, E.2
  • 77
    • 77956892317 scopus 로고
    • Phosphofructokinase
    • New York: Academic Press, Boyer PD, 3
    • Bloxham DP, Lardy HA. Phosphofructokinase. The Enzymes 1973, 8:239-278. New York: Academic Press, Boyer PD, 3.
    • (1973) The Enzymes , vol.8 , pp. 239-278
    • Bloxham, D.P.1    Lardy, H.A.2
  • 78
    • 0022244506 scopus 로고
    • The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol
    • 1152585, 2996495
    • Bais R, James HM, Rofe AM, Conyers RA. The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol. Biochem J 1985, 230:53-60. 1152585, 2996495.
    • (1985) Biochem J , vol.230 , pp. 53-60
    • Bais, R.1    James, H.M.2    Rofe, A.M.3    Conyers, R.A.4
  • 79
    • 0016422118 scopus 로고
    • Triosephosphate isomerase from human erythrocytes
    • full_text, 1128275
    • Gracy RW. Triosephosphate isomerase from human erythrocytes. Methods Enzymol 1975, 41:442-447. full_text, 1128275.
    • (1975) Methods Enzymol , vol.41 , pp. 442-447
    • Gracy, R.W.1
  • 80
    • 20544448672 scopus 로고    scopus 로고
    • The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol
    • 10.1093/toxsci/kfi158, 15788719
    • Gregus Z, Nemeti B. The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol. Toxicol Sci 2005, 85:859-869. 10.1093/toxsci/kfi158, 15788719.
    • (2005) Toxicol Sci , vol.85 , pp. 859-869
    • Gregus, Z.1    Nemeti, B.2
  • 81
    • 77956928348 scopus 로고
    • 3-Phosphoglycerate kinase
    • New York: Academic Press, Boyer PD, 3
    • Scopes RK. 3-Phosphoglycerate kinase. The Enzymes 1973, 8:335-351. New York: Academic Press, Boyer PD, 3.
    • (1973) The Enzymes , vol.8 , pp. 335-351
    • Scopes, R.K.1
  • 83
    • 21844468220 scopus 로고    scopus 로고
    • Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis
    • 10.1021/bi0474923, 15996096
    • Dombrauckas JD, Santarsiero BD, Mesecar AD. Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. Biochemistry 2005, 44:9417-9429. 10.1021/bi0474923, 15996096.
    • (2005) Biochemistry , vol.44 , pp. 9417-9429
    • Dombrauckas, J.D.1    Santarsiero, B.D.2    Mesecar, A.D.3
  • 84
    • 0020345764 scopus 로고
    • Pyruvate kinases from human erythrocytes and liver
    • full_text, 7154942
    • Kahn A, Marie J. Pyruvate kinases from human erythrocytes and liver. Methods Enzymol 1982, 90(Pt E):131-140. full_text, 7154942.
    • (1982) Methods Enzymol , vol.90 , pp. 131-140
    • Kahn, A.1    Marie, J.2
  • 85
    • 0025647066 scopus 로고
    • Purification and partial characterization of the phosphoglucomutase isozymes from human placenta
    • 10.1080/00327489008050198, 2149596
    • Fazi A, Piacentini MP, Piatti E, Accorsi A. Purification and partial characterization of the phosphoglucomutase isozymes from human placenta. Prep Biochem 1990, 20:219-240. 10.1080/00327489008050198, 2149596.
    • (1990) Prep Biochem , vol.20 , pp. 219-240
    • Fazi, A.1    Piacentini, M.P.2    Piatti, E.3    Accorsi, A.4
  • 86
    • 0033990449 scopus 로고    scopus 로고
    • The alpha-ketoglutarate dehydrogenase complex in neurodegeneration
    • 10.1016/S0197-0186(99)00114-X, 10676873
    • Gibson GE, Park LC, Sheu KF, Blass JP, Calingasan NY. The alpha-ketoglutarate dehydrogenase complex in neurodegeneration. Neurochem Int 2000, 36:97-112. 10.1016/S0197-0186(99)00114-X, 10676873.
    • (2000) Neurochem Int , vol.36 , pp. 97-112
    • Gibson, G.E.1    Park, L.C.2    Sheu, K.F.3    Blass, J.P.4    Calingasan, N.Y.5
  • 87
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: kyoto encyclopedia of genes and genomes
    • 10.1093/nar/28.1.27, 102409, 10592173
    • Kanehisa M, Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 2000, 28:27-30. 10.1093/nar/28.1.27, 102409, 10592173.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 88
    • 0346396231 scopus 로고    scopus 로고
    • Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase
    • 10.1074/jbc.M306178200, 14555658
    • Soundar S, Park JH, Huh TL, Colman RF. Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase. J Biol Chem 2003, 278:52146-52153. 10.1074/jbc.M306178200, 14555658.
    • (2003) J Biol Chem , vol.278 , pp. 52146-52153
    • Soundar, S.1    Park, J.H.2    Huh, T.L.3    Colman, R.F.4
  • 89
    • 0019199255 scopus 로고
    • Pyruvate dehydrogenase complex of ascites tumour. Activation by AMP and other properties of potential significance in metabolic regulation
    • 1162150, 7193456
    • Lazo PA, Sols A. Pyruvate dehydrogenase complex of ascites tumour. Activation by AMP and other properties of potential significance in metabolic regulation. Biochem J 1980, 190:705-710. 1162150, 7193456.
    • (1980) Biochem J , vol.190 , pp. 705-710
    • Lazo, P.A.1    Sols, A.2


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