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Volumn 84, Issue 10, 2010, Pages 4946-4959

The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B;

EID: 77951456833     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00060-10     Document Type: Article
Times cited : (17)

References (56)
  • 1
    • 34547728114 scopus 로고    scopus 로고
    • Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication
    • Allen, R. D., III, M. N. DeZalia, and S. H. Speck. 2007. Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication. Virology 365:250-259.
    • (2007) Virology , vol.365 , pp. 250-259
    • Allen III, R.D.1    DeZalia, M.N.2    Speck, S.H.3
  • 2
    • 32444444817 scopus 로고    scopus 로고
    • Identification of spliced gammaherpesvirus 68 LANA and v-cyclin transcripts and analysis of their expression in vivo during latent infection
    • Allen, R. D., III, S. Dickerson, and S. H. Speck. 2006. Identification of spliced gammaherpesvirus 68 LANA and v-cyclin transcripts and analysis of their expression in vivo during latent infection. J. Virol. 80:2055-2062.
    • (2006) J. Virol. , vol.80 , pp. 2055-2062
    • Allen III, R.D.1    Dickerson, S.2    Speck, S.H.3
  • 4
    • 0019410144 scopus 로고
    • Activation of the Epstein-Barr virus genome by 5-aza-cytidine in latently infected human lymphoid lines
    • Ben-Sasson, S. A., and G. Klein. 1981. Activation of the Epstein-Barr virus genome by 5-aza-cytidine in latently infected human lymphoid lines. Int. J. Cancer 28:131-135.
    • (1981) Int. J. Cancer , vol.28 , pp. 131-135
    • Ben-Sasson, S.A.1    Klein, G.2
  • 5
    • 19944397140 scopus 로고    scopus 로고
    • BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
    • Bhende, P. M., W. T. Seaman, H. J. Delecluse, and S. C. Kenney. 2005. BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J. Virol. 79:7338-7348.
    • (2005) J. Virol. , vol.79 , pp. 7338-7348
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.J.3    Kenney, S.C.4
  • 6
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: Patterns and paradigms
    • Cedar, H., and Y. Bergman. 2009. Linking DNA methylation and histone modification: patterns and paradigms. Nat. Rev. Genet. 10:295-304.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 7
    • 0034667777 scopus 로고    scopus 로고
    • Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation
    • Chang, L. K., and S. T. Liu. 2000. Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. Nucleic Acids Res. 28:3918-3925.
    • (2000) Nucleic Acids Res , vol.28 , pp. 3918-3925
    • Chang, L.K.1    Liu, S.T.2
  • 9
    • 0033609007 scopus 로고    scopus 로고
    • CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma
    • Christensen, J. P., R. D. Cardin, K. C. Branum, and P. C. Doherty. 1999. CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma. Proc. Natl. Acad. Sci. U. S. A. 96:5135-5140.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 5135-5140
    • Christensen, J.P.1    Cardin, R.D.2    Branum, K.C.3    Doherty, P.C.4
  • 10
    • 67449097822 scopus 로고    scopus 로고
    • Identification of infected B-cell populations by using a recombinant murine gammaherpesvirus 68 expressing a fluorescent protein
    • Collins, C. M., J. M. Boss, and S. H. Speck. 2009. Identification of infected B-cell populations by using a recombinant murine gammaherpesvirus 68 expressing a fluorescent protein. J. Virol. 83:6484-6493.
    • (2009) J. Virol. , vol.83 , pp. 6484-6493
    • Collins, C.M.1    Boss, J.M.2    Speck, S.H.3
  • 11
    • 43249126604 scopus 로고    scopus 로고
    • Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors
    • Countryman, J. K., L. Gradoville, and G. Miller. 2008. Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors. J. Virol. 82:4706-4719.
    • (2008) J. Virol. , vol.82 , pp. 4706-4719
    • Countryman, J.K.1    Gradoville, L.2    Miller, G.3
  • 12
    • 24044481947 scopus 로고    scopus 로고
    • Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization
    • Dodge, J. E., M. Okano, F. Dick, N. Tsujimoto, T. Chen, S. Wang, Y. Ueda, N. Dyson, and E. Li. 2005. Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J. Biol. Chem. 280:17986-17991.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17986-17991
    • Dodge, J.E.1    Okano, M.2    Dick, F.3    Tsujimoto, N.4    Chen, T.5    Wang, S.6    Ueda, Y.7    Dyson, N.8    Li, E.9
  • 13
    • 0030979780 scopus 로고    scopus 로고
    • Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: A role for CD8 T cells
    • Dutia, B. M., C. J. Clarke, D. J. Allen, and A. A. Nash. 1997. Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells. J. Virol. 71:4278-4283.
    • (1997) J. Virol. , vol.71 , pp. 4278-4283
    • Dutia, B.M.1    Clarke, C.J.2    Allen, D.J.3    Nash, A.A.4
  • 14
    • 10044252330 scopus 로고    scopus 로고
    • Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines
    • DOI 10.1128/JVI.78.24.14062-14065.2004
    • Elliott, J., E. B. Goodhew, L. T. Krug, N. Shakhnovsky, L. Yoo, and S. H. Speck. 2004. Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines. J. Virol. 78:14062-14065. (Pubitemid 39612805)
    • (2004) Journal of Virology , vol.78 , Issue.24 , pp. 14062-14065
    • Elliott, J.1    Goodhew, E.B.2    Krug, L.T.3    Shakhnovsky, N.4    Yoo, L.5    Speck, S.H.6
  • 15
    • 47749101765 scopus 로고    scopus 로고
    • Establishment of B-cell lines latently infected with reactivation- competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade
    • Forrest, J. C., and S. H. Speck. 2008. Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade. J. Virol. 82:7688-7699.
    • (2008) J. Virol. , vol.82 , pp. 7688-7699
    • Forrest, J.C.1    Speck, S.H.2
  • 16
    • 38949112498 scopus 로고    scopus 로고
    • Germinal center B-cell-associated DNA hypomethylation at transcriptional regions of the AID gene
    • Fujimura, S., T. Matsui, K. Kuwahara, K. Maeda, and N. Sakaguchi. 2008. Germinal center B-cell-associated DNA hypomethylation at transcriptional regions of the AID gene. Mol. Immunol. 45:1712-1719.
    • (2008) Mol. Immunol. , vol.45 , pp. 1712-1719
    • Fujimura, S.1    Matsui, T.2    Kuwahara, K.3    Maeda, K.4    Sakaguchi, N.5
  • 17
    • 0036827720 scopus 로고    scopus 로고
    • Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice
    • DOI 10.1128/JVI.76.22.11460-11468.2002
    • Gangappa, S., S. B. Kapadia, S. H. Speck, and H. W. Virgin IV. 2002. Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice. J. Virol. 76:11460-11468. (Pubitemid 35231302)
    • (2002) Journal of Virology , vol.76 , Issue.22 , pp. 11460-11468
    • Gangappa, S.1    Kapadia, S.B.2    Speck, S.H.3    Virgin IV, H.W.4
  • 18
    • 41949132774 scopus 로고    scopus 로고
    • Role for MyD88 signaling in murine gammaherpesvirus 68 latency
    • Gargano, L. M., J. M. Moser, and S. H. Speck. 2008. Role for MyD88 signaling in murine gammaherpesvirus 68 latency. J. Virol. 82:3853-3863.
    • (2008) J. Virol. , vol.82 , pp. 3853-3863
    • Gargano, L.M.1    Moser, J.M.2    Speck, S.H.3
  • 19
    • 58149396884 scopus 로고    scopus 로고
    • Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency
    • Gray, K. S., R. D. Allen III, M. L. Farrell, J. C. Forrest, and S. H. Speck. 2009. Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency. J. Virol. 83: 314-328.
    • (2009) J. Virol. , vol.83 , pp. 314-328
    • Gray, K.S.1    Allen III, R.D.2    Farrell, M.L.3    Forrest, J.C.4    Speck, S.H.5
  • 20
    • 0035136167 scopus 로고    scopus 로고
    • CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50
    • DOI 10.1128/JVI.75.4.1909-1917.2001
    • Gwack, Y., H. Byun, S. Hwang, C. Lim, and J. Choe. 2001. CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50. J. Virol. 75:1909-1917. (Pubitemid 32110181)
    • (2001) Journal of Virology , vol.75 , Issue.4 , pp. 1909-1917
    • Gwack, Y.1    Byun, H.2    Hwang, S.3    Lim, C.4    Choe, J.5
  • 21
    • 0037155143 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus open reading frame 50 stimulates the transcriptional activity of STAT3
    • Gwack, Y., S. Hwang, C. Lim, Y. S. Won, C. H. Lee, and J. Choe. 2002. Kaposi's sarcoma-associated herpesvirus open reading frame 50 stimulates the transcriptional activity of STAT3. J. Biol. Chem. 277:6438-6442.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6438-6442
    • Gwack, Y.1    Hwang, S.2    Lim, C.3    Won, Y.S.4    Lee, C.H.5    Choe, J.6
  • 22
    • 67649170780 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1
    • Heather, J., K. Flower, S. Isaac, and A. J. Sinclair. 2009. The Epstein-Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1. J. Gen. Virol. 90:1450-1454.
    • (2009) J. Gen. Virol. , vol.90 , pp. 1450-1454
    • Heather, J.1    Flower, K.2    Isaac, S.3    Sinclair, A.J.4
  • 23
    • 29644436321 scopus 로고    scopus 로고
    • Molecular enzymology of mammalian DNA methyltransferases
    • Jeltsch, A. 2006. Molecular enzymology of mammalian DNA methyltransferases. Curr. Top. Microbiol. Immunol. 301:203-225.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.301 , pp. 203-225
    • Jeltsch, A.1
  • 24
    • 3042584653 scopus 로고    scopus 로고
    • Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
    • DOI 10.1038/nature02633
    • Kaneda, M., M. Okano, K. Hata, T. Sado, N. Tsujimoto, E. Li, and H. Sasaki. 2004. Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429:900-903. (Pubitemid 38843304)
    • (2004) Nature , vol.429 , Issue.6994 , pp. 900-903
    • Kaneda, M.1    Okano, M.2    Hata, K.3    Sado, T.4    Tsujimoto, H.5    Li, E.6    Sasaki, H.7
  • 25
    • 42949174160 scopus 로고    scopus 로고
    • Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein
    • Karlsson, Q. H., C. Schelcher, E. Verrall, C. Petosa, and A. J. Sinclair. 2008. Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein. PLoS Pathog. 4:e1000005.
    • (2008) PLoS Pathog , vol.4
    • Karlsson, Q.H.1    Schelcher, C.2    Verrall, E.3    Petosa, C.4    Sinclair, A.J.5
  • 26
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • Klug, M., and M. Rehli. 2006. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 1:127-130.
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 27
    • 14744269431 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jκ, the major downstream effector of the notch signaling pathway
    • DOI 10.1128/JVI.79.6.3468-3478.2005
    • Lan, K., D. A. Kuppers, and E. S. Robertson. 2005. Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway. J. Virol. 79:3468-3478. (Pubitemid 40327935)
    • (2005) Journal of Virology , vol.79 , Issue.6 , pp. 3468-3478
    • Lan, K.1    Kuppers, D.A.2    Robertson, E.S.3
  • 28
    • 2642586357 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: A potential mechanism for virus-mediated control of latency
    • DOI 10.1128/JVI.78.12.6585-6594.2004
    • Lan, K., D. A. Kuppers, S. C. Verma, and E. S. Robertson. 2004. Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency. J. Virol. 78:6585-6594. (Pubitemid 38715955)
    • (2004) Journal of Virology , vol.78 , Issue.12 , pp. 6585-6594
    • Lan, K.1    Kuppers, D.A.2    Verma, S.C.3    Robertson, E.S.4
  • 29
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li, E. 2002. Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 3:662-673.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 662-673
    • Li, E.1
  • 30
    • 0033946769 scopus 로고    scopus 로고
    • Characterization of gammaherpesvirus 68 gene 50 transcription
    • Liu, S., I. V. Pavlova, H. W. Virgin IV, and S. H. Speck. 2000. Characterization of gammaherpesvirus 68 gene 50 transcription. J. Virol. 74:2029-2037.
    • (2000) J. Virol. , vol.74 , pp. 2029-2037
    • Liu, S.1    Pavlova, I.V.2    Virgin IV, H.W.3    Speck, S.H.4
  • 31
    • 0018384722 scopus 로고
    • Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate
    • DOI 10.1016/0042-6822(79)90455-0
    • Luka, J., B. Kallin, and G. Klein. 1979. Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate. Virology 94:228-231. (Pubitemid 9164800)
    • (1979) Virology , vol.94 , Issue.1 , pp. 228-231
    • Luka, J.1    Kallin, B.2    Klein, G.3
  • 32
    • 0032567394 scopus 로고    scopus 로고
    • Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein
    • Lukac, D. M., R. Renne, J. R. Kirshner, and D. Ganem. 1998. Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. Virology 252:304-312.
    • (1998) Virology , vol.252 , pp. 304-312
    • Lukac, D.M.1    Renne, R.2    Kirshner, J.R.3    Ganem, D.4
  • 33
    • 1642421746 scopus 로고    scopus 로고
    • Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68
    • May, J. S., H. M. Coleman, B. Smillie, S. Efstathiou, and P. G. Stevenson. 2004. Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68. J. Gen. Virol. 85:137-146.
    • (2004) J. Gen. Virol. , vol.85 , pp. 137-146
    • May, J.S.1    Coleman, H.M.2    Smillie, B.3    Efstathiou, S.4    Stevenson, P.G.5
  • 35
    • 63449133614 scopus 로고    scopus 로고
    • Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
    • Niller, H. H., H. Wolf, and J. Minarovits. 2009. Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia. Semin. Cancer Biol. 19:158-164.
    • (2009) Semin. Cancer Biol. , vol.19 , pp. 158-164
    • Niller, H.H.1    Wolf, H.2    Minarovits, J.3
  • 36
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano, M., D. W. Bell, D. A. Haber, and E. Li. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 37
    • 0036040932 scopus 로고    scopus 로고
    • Methylation of the EBV genome and establishment of restricted latency in low-passage EBV-infected 293 epithelial cells
    • Paulson, E. J., J. D. Fingeroth, J. L. Yates, and S. H. Speck. 2002. Methylation of the EBV genome and establishment of restricted latency in low-passage EBV-infected 293 epithelial cells. Virology 299:109-121.
    • (2002) Virology , vol.299 , pp. 109-121
    • Paulson, E.J.1    Fingeroth, J.D.2    Yates, J.L.3    Speck, S.H.4
  • 38
    • 0032752850 scopus 로고    scopus 로고
    • Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals
    • Paulson, E. J., and S. H. Speck. 1999. Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals. J. Virol. 73:9959-9968.
    • (1999) J. Virol. , vol.73 , pp. 9959-9968
    • Paulson, E.J.1    Speck, S.H.2
  • 39
    • 0037695160 scopus 로고    scopus 로고
    • Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication
    • Pavlova, I. V., H. W. Virgin IV, and S. H. Speck. 2003. Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication. J. Virol. 77:5731-5739.
    • (2003) J. Virol. , vol.77 , pp. 5731-5739
    • Pavlova, I.V.1    Virgin IV, H.W.2    Speck, S.H.3
  • 40
    • 0030818183 scopus 로고    scopus 로고
    • B lymphocyte-specific, Cre-mediated mutagenesis in mice
    • Rickert, R. C., J. Roes, and K. Rajewsky. 1997. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25:1317-1318.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1317-1318
    • Rickert, R.C.1    Roes, J.2    Rajewsky, K.3
  • 41
    • 3242886298 scopus 로고    scopus 로고
    • Regulation of activation and recombination of the murine Igkappa locus
    • Schlissel, M. S. 2004. Regulation of activation and recombination of the murine Igkappa locus. Immunol. Rev. 200:215-223.
    • (2004) Immunol. Rev. , vol.200 , pp. 215-223
    • Schlissel, M.S.1
  • 42
    • 0030606260 scopus 로고    scopus 로고
    • Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay
    • Slifka, M. K., and R. Ahmed. 1996. Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay. J. Immunol. Methods 199:37-46.
    • (1996) J. Immunol. Methods , vol.199 , pp. 37-46
    • Slifka, M.K.1    Ahmed, R.2
  • 43
    • 34249943220 scopus 로고    scopus 로고
    • The Rta/Orf50 transactivator proteins of the gamma-herpesviridae
    • Staudt, M. R., and D. P. Dittmer. 2007. The Rta/Orf50 transactivator proteins of the gamma-herpesviridae. Curr. Top. Microbiol. Immunol. 312:71-100.
    • (2007) Curr. Top. Microbiol. Immunol. , vol.312 , pp. 71-100
    • Staudt, M.R.1    Dittmer, D.P.2
  • 44
    • 0031907464 scopus 로고    scopus 로고
    • Kinetic analysis of the specific host response to a murine gammaherpesvirus
    • Stevenson, P. G., and P. C. Doherty. 1998. Kinetic analysis of the specific host response to a murine gammaherpesvirus. J. Virol. 72:943-949.
    • (1998) J. Virol. , vol.72 , pp. 943-949
    • Stevenson, P.G.1    Doherty, P.C.2
  • 45
    • 0032167919 scopus 로고    scopus 로고
    • A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus
    • Sun, R., S. F. Lin, L. Gradoville, Y. Yuan, F. Zhu, and G. Miller. 1998. A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. Proc. Natl. Acad. Sci. U. S. A. 95:10866-10871.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 10866-10871
    • Sun, R.1    Lin, S.F.2    Gradoville, L.3    Yuan, Y.4    Zhu, F.5    Miller, G.6
  • 46
    • 0022397783 scopus 로고
    • Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle
    • Szyf, M., L. Eliasson, V. Mann, G. Klein, and A. Razin. 1985. Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle. Proc. Natl. Acad. Sci. U. S. A. 82:8090-8094.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 8090-8094
    • Szyf, M.1    Eliasson, L.2    Mann, V.3    Klein, G.4    Razin, A.5
  • 47
    • 34247337999 scopus 로고    scopus 로고
    • De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
    • Tadokoro, Y., H. Ema, M. Okano, E. Li, and H. Nakauchi. 2007. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J. Exp. Med. 204:715-722.
    • (2007) J. Exp. Med. , vol.204 , pp. 715-722
    • Tadokoro, Y.1    Ema, H.2    Okano, M.3    Li, E.4    Nakauchi, H.5
  • 48
    • 0036712913 scopus 로고    scopus 로고
    • Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells
    • Tao, Q., H. Huang, T. M. Geiman, C. Y. Lim, L. Fu, G. H. Qiu, and K. D. Robertson. 2002. Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum. Mol. Genet. 11:2091-2102.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2091-2102
    • Tao, Q.1    Huang, H.2    Geiman, T.M.3    Lim, C.Y.4    Fu, L.5    Qiu, G.H.6    Robertson, K.D.7
  • 49
    • 27744535391 scopus 로고    scopus 로고
    • Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice
    • Tarakanova, V. L., F. Suarez, S. A. Tibbetts, M. A. Jacoby, K. E. Weck, J. L. Hess, S. H. Speck, and H. W. Virgin IV. 2005. Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice. J. Virol. 79:14668-14679.
    • (2005) J. Virol. , vol.79 , pp. 14668-14679
    • Tarakanova, V.L.1    Suarez, F.2    Tibbetts, S.A.3    Jacoby, M.A.4    Weck, K.E.5    Hess, J.L.6    Speck, S.H.7    Virgin IV, H.W.8
  • 50
    • 0032978606 scopus 로고    scopus 로고
    • Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice
    • Virgin, H. W., IV, R. M. Presti, X. Y. Li, C. Liu, and S. H. Speck. 1999. Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J. Virol. 73:2321-2332.
    • (1999) J. Virol. , vol.73 , pp. 2321-2332
    • Virgin IV, H.W.1    Presti, R.M.2    Li, X.Y.3    Liu, C.4    Speck, S.H.5
  • 51
    • 0029817996 scopus 로고    scopus 로고
    • Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68
    • Weck, K. E., M. L. Barkon, L. I. Yoo, S. H. Speck, and H. W. Virgin IV. 1996. Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J. Virol. 70:6775-6780.
    • (1996) J. Virol. , vol.70 , pp. 6775-6780
    • Weck, K.E.1    Barkon, M.L.2    Yoo, L.I.3    Speck, S.H.4    Virgin IV, H.W.5
  • 52
    • 0033061214 scopus 로고    scopus 로고
    • B cells regulate murine gammaherpesvirus 68 latency
    • Weck, K. E., S. S. Kim, H. W. Virgin IV, and S. H. Speck. 1999. B cells regulate murine gammaherpesvirus 68 latency. J. Virol. 73:4651-4661. (Pubitemid 29246723)
    • (1999) Journal of Virology , vol.73 , Issue.6 , pp. 4651-4661
    • Weck, K.E.1    Kim, S.S.2    Virgin IV, H.W.3    Speck, S.H.4
  • 53
    • 0038784895 scopus 로고    scopus 로고
    • Long-term latent murine gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo
    • Willer, D. O., and S. H. Speck. 2003. Long-term latent murine gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo. J. Virol. 77:8310-8321.
    • (2003) J. Virol. , vol.77 , pp. 8310-8321
    • Willer, D.O.1    Speck, S.H.2
  • 54
    • 0034842666 scopus 로고    scopus 로고
    • Function of Rta is essential for lytic replication of murine gammaherpesvirus 68
    • Wu, T. T., L. Tong, T. Rickabaugh, S. Speck, and R. Sun. 2001. Function of Rta is essential for lytic replication of murine gammaherpesvirus 68. J. Virol. 75:9262-9273.
    • (2001) J. Virol. , vol.75 , pp. 9262-9273
    • Wu, T.T.1    Tong, L.2    Rickabaugh, T.3    Speck, S.4    Sun, R.5
  • 55
    • 0034109365 scopus 로고    scopus 로고
    • Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency
    • Wu, T. T., E. J. Usherwood, J. P. Stewart, A. A. Nash, and R. Sun. 2000. Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency. J. Virol. 74:3659-3667.
    • (2000) J. Virol. , vol.74 , pp. 3659-3667
    • Wu, T.T.1    Usherwood, E.J.2    Stewart, J.P.3    Nash, A.A.4    Sun, R.5
  • 56
    • 84887212508 scopus 로고    scopus 로고
    • RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation
    • Yang, Z., H. Tang, H. Huang, and H. Deng. 2009. RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation. PLoS One 4:e4556.
    • (2009) PLoS One , vol.4
    • Yang, Z.1    Tang, H.2    Huang, H.3    Deng, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.