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Volumn 73, Issue 12, 1999, Pages 9959-9968

Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; EPSTEIN BARR VIRUS; HOST CELL; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; VIRUS CELL INTERACTION; VIRUS LATENCY;

EID: 0032752850     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.12.9959-9968.1999     Document Type: Article
Times cited : (67)

References (77)
  • 1
    • 0026505622 scopus 로고
    • Host-cell-phenotype-dependent control of the BCR2/BWR1 promoter complex regulates the expression of Epstein-Barr virus nuclear antigens 2-6
    • Erratum, 89:6225
    • Altiok, E., J. Minarovits, L. F. Hu, B. Contreras-Brodin, G. Klein, and I. Ernberg. 1992. Host-cell-phenotype-dependent control of the BCR2/BWR1 promoter complex regulates the expression of Epstein-Barr virus nuclear antigens 2-6. Proc. Natl. Acad. Sci. USA 89:905-909. (Erratum, 89:6225.)
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 905-909
    • Altiok, E.1    Minarovits, J.2    Hu, L.F.3    Contreras-Brodin, B.4    Klein, G.5    Ernberg, I.6
  • 3
    • 0027280881 scopus 로고
    • Methylation and imprinting: From host defense to gene regulation?
    • Barlow, D. P. 1993. Methylation and imprinting: from host defense to gene regulation? Science 260:309-310.
    • (1993) Science , vol.260 , pp. 309-310
    • Barlow, D.P.1
  • 4
    • 0032126345 scopus 로고    scopus 로고
    • Cytosine methylation of repeated sequences in eukaryotes: The role of DNA pairing
    • Bender, J. 1998. Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing. Trends Biochem. Sci. 23:252-256.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 252-256
    • Bender, J.1
  • 5
    • 0032574859 scopus 로고    scopus 로고
    • Gene silencing. Methylation meets acetylation
    • News; comment
    • Bestor, T. H. 1998. Gene silencing. Methylation meets acetylation. Nature 393:311-312. (News; comment.)
    • (1998) Nature , vol.393 , pp. 311-312
    • Bestor, T.H.1
  • 6
    • 0030115772 scopus 로고    scopus 로고
    • Creation of genomic methylation patterns
    • Bestor, T. H., and B. Tycko. 1996. Creation of genomic methylation patterns. Nat. Genet. 12:363-367.
    • (1996) Nat. Genet. , vol.12 , pp. 363-367
    • Bestor, T.H.1    Tycko, B.2
  • 7
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya, S. K., S. Ramchandani, N. Cervoni, and M. Szyf. 1999. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397:579-583.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 8
    • 0026583975 scopus 로고
    • Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein
    • Boyes, J. and A. Bird. 1992. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein. EMBO J. 11:327-333.
    • (1992) EMBO J. , vol.11 , pp. 327-333
    • Boyes, J.1    Bird, A.2
  • 10
    • 0029067481 scopus 로고
    • A subpopulation of normal B cells latently infected with Epstein-Barr virus resembles Burkitt lymphoma cells in expressing EBNA-1 but not EBNA-2 or LMP1
    • Chen, F., J. Z. Zou, L. di Renzo, G. Winberg, L. F. Hu, E. Klein, G. Klein, and I. Ernberg. 1995. A subpopulation of normal B cells latently infected with Epstein-Barr virus resembles Burkitt lymphoma cells in expressing EBNA-1 but not EBNA-2 or LMP1. J. Virol. 69:3752-3758.
    • (1995) J. Virol. , vol.69 , pp. 3752-3758
    • Chen, F.1    Zou, J.Z.2    Di Renzo, L.3    Winberg, G.4    Hu, L.F.5    Klein, E.6    Klein, G.7    Ernberg, I.8
  • 11
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate- phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate- phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 13
    • 0033015741 scopus 로고    scopus 로고
    • Expression of EBNA-1 mRNA is regulated by cell cycle during Epstein-Barr virus type I latency
    • Davenport, M. G., and J. S. Pagano. 1999. Expression of EBNA-1 mRNA is regulated by cell cycle during Epstein-Barr virus type I latency. J. Virol. 73:3154-3161.
    • (1999) J. Virol. , vol.73 , pp. 3154-3161
    • Davenport, M.G.1    Pagano, J.S.2
  • 14
    • 0029947349 scopus 로고    scopus 로고
    • Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals
    • Decker, L. L., L. D. Klaman, and D. A. Thorley-Lawson. 1996. Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals. J. Virol. 70:3286-3289.
    • (1996) J. Virol. , vol.70 , pp. 3286-3289
    • Decker, L.L.1    Klaman, L.D.2    Thorley-Lawson, D.A.3
  • 15
    • 0025313893 scopus 로고
    • Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri
    • Efstathiou, S., Y. M. Ho, S. Hall, C. J. Styles, S. D. Scott, and U. A. Gompels. 1990. Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri. J. Gen. Virol. 71:1365-1372.
    • (1990) J. Gen. Virol. , vol.71 , pp. 1365-1372
    • Efstathiou, S.1    Ho, Y.M.2    Hall, S.3    Styles, C.J.4    Scott, S.D.5    Gompels, U.A.6
  • 16
    • 0024458683 scopus 로고
    • The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus
    • Erratum, 71:499, 1990
    • Ernberg, I., K. Falk, J. Minarovits, P. Busson, T. Tursz, M. G. Masucci, and Klein. 1989. The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus. J. Gen. Virol. 70:2989-3002. (Erratum, 71:499, 1990.)
    • (1989) J. Gen. Virol. , vol.70 , pp. 2989-3002
    • Ernberg, I.1    Falk, K.2    Minarovits, J.3    Busson, P.4    Tursz, T.5    Masucci, M.G.6    Klein7
  • 17
    • 0020435972 scopus 로고
    • Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
    • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 1044-1051
    • Gorman, C.M.1    Moffat, L.F.2    Howard, B.H.3
  • 18
    • 0019827634 scopus 로고
    • Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation
    • Groudine, M., R. Eisenman, and H. Weintraub. 1981. Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation. Nature 292:311-317.
    • (1981) Nature , vol.292 , pp. 311-317
    • Groudine, M.1    Eisenman, R.2    Weintraub, H.3
  • 19
    • 85009545299 scopus 로고
    • Enhancement of mRNA synthesis from Marek's disease virus genome in the lymphoblastoid cell line, MDCC-MSB1, by 5-azacytidine
    • Hayashi, M., T. Furuichi, S. Ren, E. Isogai, M. Nonoyama, and S. Namioka. 1994. Enhancement of mRNA synthesis from Marek's disease virus genome in the lymphoblastoid cell line, MDCC-MSB1, by 5-azacytidine. J. Vet. Med. Sci. 56:287-291.
    • (1994) J. Vet. Med. Sci. , vol.56 , pp. 287-291
    • Hayashi, M.1    Furuichi, T.2    Ren, S.3    Isogai, E.4    Nonoyama, M.5    Namioka, S.6
  • 20
    • 0014139019 scopus 로고
    • Immunofluorescence and herpes-type virus particles in the P3HR-1 Burkitt lymphoma cell line
    • Hinuma, Y., M. Konn, J. Yamaguchi, D. J. Wudarski, J. R. J. Blakeslee, and J. T. J. Grace. 1967. Immunofluorescence and herpes-type virus particles in the P3HR-1 Burkitt lymphoma cell line. J. Virol. 1:1045-1051.
    • (1967) J. Virol. , vol.1 , pp. 1045-1051
    • Hinuma, Y.1    Konn, M.2    Yamaguchi, J.3    Wudarski, D.J.4    Blakeslee, J.R.J.5    Grace, J.T.J.6
  • 21
    • 0024557192 scopus 로고
    • Deviations from expected frequencies of CpG dinucleotides in herpesvirus DNAs may be diagnostic of differences in the states of their latent genomes
    • Honess, R. W., U. A. Gompels, B. G. Barrell, M. Craxton, K. R. Cameron, R. Staden, Y. N. Chang, and G. S. Hayward. 1989. Deviations from expected frequencies of CpG dinucleotides in herpesvirus DNAs may be diagnostic of differences in the states of their latent genomes. J. Gen. Virol. 70:837-855.
    • (1989) J. Gen. Virol. , vol.70 , pp. 837-855
    • Honess, R.W.1    Gompels, U.A.2    Barrell, B.G.3    Craxton, M.4    Cameron, K.R.5    Staden, R.6    Chang, Y.N.7    Hayward, G.S.8
  • 22
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh, C. L. 1994. Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol. 14:5487-5494.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5487-5494
    • Hsieh, C.L.1
  • 23
    • 0021861476 scopus 로고
    • Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity
    • Jahner, D., and R. Jaenisch. 1985. Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity. Nature 315:594-597.
    • (1985) Nature , vol.315 , pp. 594-597
    • Jahner, D.1    Jaenisch, R.2
  • 24
  • 25
    • 0026555176 scopus 로고
    • Methylation of discrete sites within the enhancer region regulates the activity of the Epstein-Barr virus BamHI W promoter in Burkitt lymphoma lines
    • Jansson, A., M. Masucci, and L. Rymo. 1992. Methylation of discrete sites within the enhancer region regulates the activity of the Epstein-Barr virus BamHI W promoter in Burkitt lymphoma lines. J. Virol. 66:62-69.
    • (1992) J. Virol. , vol.66 , pp. 62-69
    • Jansson, A.1    Masucci, M.2    Rymo, L.3
  • 26
    • 0026576819 scopus 로고
    • Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter
    • Jin, X. W., and S. H. Speck. 1992. Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter. J. Virol. 66:2846-2852.
    • (1992) J. Virol. , vol.66 , pp. 2846-2852
    • Jin, X.W.1    Speck, S.H.2
  • 28
    • 0023111412 scopus 로고
    • Methylation of Marek's disease virus DNA in chicken T-lymphoblastoid cell lines
    • Kanamori, A., K. Ikuta, S. Ueda, S. Kato, and K. Hirai. 1987 Methylation of Marek's disease virus DNA in chicken T-lymphoblastoid cell lines. J. Gen. Virol. 68:1485-1490.
    • (1987) J. Gen. Virol. , vol.68 , pp. 1485-1490
    • Kanamori, A.1    Ikuta, K.2    Ueda, S.3    Kato, S.4    Hirai, K.5
  • 29
    • 0022489633 scopus 로고
    • Significant potential secondary structures in the Epstein-Barr virus genome
    • Karlin, S. 1986. Significant potential secondary structures in the Epstein-Barr virus genome. Proc. Natl. Acad. Sci. USA 83:6915-6919.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6915-6919
    • Karlin, S.1
  • 30
    • 0028221062 scopus 로고
    • Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?
    • Karlin, S., W. Doerfler, and L. R. Cardon. 1994. Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses? J. Virol. 68:2889-2897.
    • (1994) J. Virol. , vol.68 , pp. 2889-2897
    • Karlin, S.1    Doerfler, W.2    Cardon, L.R.3
  • 31
    • 0027958329 scopus 로고
    • Molecular evolution of herpesviruses: Genomic and protein sequence comparisons
    • Karlin, S., E. S. Mocarski, and G. A. Schachtel. 1994. Molecular evolution of herpesviruses: genomic and protein sequence comparisons. J. Virol. 68: 1886-1902.
    • (1994) J. Virol. , vol.68 , pp. 1886-1902
    • Karlin, S.1    Mocarski, E.S.2    Schachtel, G.A.3
  • 32
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a time-dependent repression of transcription initiation
    • Kass, S. U., N. Landsberger, and A. P. Wolffe. 1997. DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol. 7:157-165.
    • (1997) Curr. Biol. , vol.7 , pp. 157-165
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 33
    • 0015509615 scopus 로고
    • Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus
    • Klein, G., L. Dombos, and B. Gothoskar. 1972 Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus. Int. J. Cancer 10:44-57.
    • (1972) Int. J. Cancer , vol.10 , pp. 44-57
    • Klein, G.1    Dombos, L.2    Gothoskar, B.3
  • 34
    • 0026465280 scopus 로고
    • The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle
    • Lear, A. L., M. Rowe, M. G. Kurilla, S. Lee, S. Henderson, E. Kieff, and A. B. Rickinson. 1992. The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle. J. Virol. 66:7461-7468.
    • (1992) J. Virol. , vol.66 , pp. 7461-7468
    • Lear, A.L.1    Rowe, M.2    Kurilla, M.G.3    Lee, S.4    Henderson, S.5    Kieff, E.6    Rickinson, A.B.7
  • 35
    • 0026562711 scopus 로고
    • BHRF1 of Epstein-Barr virus, which is homologous to human proto-oncogene bcl2, is not essential for transformation of B cells or for virus replication in vitro
    • Lee, M. A., and J. L. Yates. 1992. BHRF1 of Epstein-Barr virus, which is homologous to human proto-oncogene bcl2, is not essential for transformation of B cells or for virus replication in vitro. J. Virol. 66:1899-1906.
    • (1992) J. Virol. , vol.66 , pp. 1899-1906
    • Lee, M.A.1    Yates, J.L.2
  • 37
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., T. H. Bestor, and R. Jaenisch. 1992. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 38
    • 0027960055 scopus 로고
    • Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
    • Macleod, D., J. Charlton, J. Mullins, and A. P. Bird. 1994 Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 8:2282-2292.
    • (1994) Genes Dev. , vol.8 , pp. 2282-2292
    • Macleod, D.1    Charlton, J.2    Mullins, J.3    Bird, A.P.4
  • 39
    • 0024381772 scopus 로고
    • 5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line Rael
    • Masucci, M. G., B. Contreras-Salazar, E. Ragnar, K. Falk, J. Minarorits, Ernberg, and G. Klein. 1989. 5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line Rael. J. Virol. 63:3135-3141.
    • (1989) J. Virol. , vol.63 , pp. 3135-3141
    • Masucci, M.G.1    Contreras-Salazar, B.2    Ragnar, E.3    Falk, K.4    Minarorits, J.5    Ernberg6    Klein, G.7
  • 40
    • 0031050083 scopus 로고    scopus 로고
    • Methylation analysis using bisulfite genomic sequencing: Application to small numbers of intact cells
    • McDonald, L. E., and G. F. Kay. 1997. Methylation analysis using bisulfite genomic sequencing: application to small numbers of intact cells. BioTechniques 22:272-274.
    • (1997) BioTechniques , vol.22 , pp. 272-274
    • McDonald, L.E.1    Kay, G.F.2
  • 41
    • 0028328903 scopus 로고
    • Sequence-specific methylation inhibits the activity of the Epstein-Barr virus LMP 1 and BCR2 enhancer-promoter regions
    • Minarovits, J., L. F. Hu, S. Minarovits-Kormuta, G. Klein, and I. Ernberg. 1994. Sequence-specific methylation inhibits the activity of the Epstein-Barr virus LMP 1 and BCR2 enhancer-promoter regions. Virology 200:661-667.
    • (1994) Virology , vol.200 , pp. 661-667
    • Minarovits, J.1    Hu, L.F.2    Minarovits-Kormuta, S.3    Klein, G.4    Ernberg, I.5
  • 43
    • 0031007613 scopus 로고    scopus 로고
    • Identification of the site of Epstein-Barr virus persistence in vivo as a resting B cell
    • Miyashita, E. M., B. Yang, G. J. Babcock, and D. A. Thorley-Lawson. 1997. Identification of the site of Epstein-Barr virus persistence in vivo as a resting B cell. J. Virol. 71:4882-4891.
    • (1997) J. Virol. , vol.71 , pp. 4882-4891
    • Miyashita, E.M.1    Yang, B.2    Babcock, G.J.3    Thorley-Lawson, D.A.4
  • 44
    • 0028939583 scopus 로고
    • A novel form of Epstein-Barr virus latency in normal B cells in vivo
    • Miyashita, E. M., B. Yang, K. M. Lam, D. H. Crawford, and D. A. Thorley-Lawson. 1995. A novel form of Epstein-Barr virus latency in normal B cells in vivo. Cell 80:593-601.
    • (1995) Cell , vol.80 , pp. 593-601
    • Miyashita, E.M.1    Yang, B.2    Lam, K.M.3    Crawford, D.H.4    Thorley-Lawson, D.A.5
  • 45
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan, X., H. H. Ng, C. A. Johnson, C. D. Laherty, B. M. Turner, R. N. Eisenman, and A. Bird. 1998. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 46
    • 0029656132 scopus 로고    scopus 로고
    • Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein
    • Nonkwelo, C., J. Skinner, A. Bell, A. Rickinson, and J. Sample. 1996. Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein. J. Virol. 70:623-627.
    • (1996) J. Virol. , vol.70 , pp. 623-627
    • Nonkwelo, C.1    Skinner, J.2    Bell, A.3    Rickinson, A.4    Sample, J.5
  • 47
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Letter
    • Okano, M., S. Xie, and E. Li. 1998. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19: 219-220. (Letter.)
    • (1998) Nat. Genet. , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 48
    • 0031060288 scopus 로고    scopus 로고
    • Regulation of EBNA gene transcription in lymphoblastoid cell lines: Characterization of sequences downstream of BCR2 (Cp)
    • Puglielli, M. T., N. Desai, and S. H. Speck. 1997. Regulation of EBNA gene transcription in lymphoblastoid cell lines: characterization of sequences downstream of BCR2 (Cp). J. Virol. 71:120-128.
    • (1997) J. Virol. , vol.71 , pp. 120-128
    • Puglielli, M.T.1    Desai, N.2    Speck, S.H.3
  • 49
    • 0029816091 scopus 로고    scopus 로고
    • oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines
    • Puglielli, M. T., M. Woisetschlaeger, and S. H. Speck. 1996. oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines. J. Virol. 70:5758-5768.
    • (1996) J. Virol. , vol.70 , pp. 5758-5768
    • Puglielli, M.T.1    Woisetschlaeger, M.2    Speck, S.H.3
  • 50
    • 0026764617 scopus 로고
    • Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes
    • Qu, L., and D. T. Rowe. 1992. Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes. J. Virol. 66:3715-3724.
    • (1992) J. Virol. , vol.66 , pp. 3715-3724
    • Qu, L.1    Rowe, D.T.2
  • 51
    • 0028961759 scopus 로고
    • A bisulfite method of 5-methylcytosine mapping that minimizes template degradation
    • Raizis, A. M., F. Schmitt, and J. P. Jost. 1995. A bisulfite method of 5-methylcytosine mapping that minimizes template degradation. Anal. Biochem. 226:161-166.
    • (1995) Anal. Biochem. , vol.226 , pp. 161-166
    • Raizis, A.M.1    Schmitt, F.2    Jost, J.P.3
  • 52
    • 0017712873 scopus 로고
    • Mechanism of the establishment of Epstein-Barr virus genome-containing lymphoid cell lines from infectious mononudeosis patients: Studies with phosphonoacetate
    • Rickinson, A. B., S. Finerty, and M. A. Epstein. 1977. Mechanism of the establishment of Epstein-Barr virus genome-containing lymphoid cell lines from infectious mononudeosis patients: studies with phosphonoacetate. Int. J. Cancer 20:861-868.
    • (1977) Int. J. Cancer , vol.20 , pp. 861-868
    • Rickinson, A.B.1    Finerty, S.2    Epstein, M.A.3
  • 53
    • 0000942113 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • B. N. Fields et al. (ed.), Lippincott-Raven, Philadelphia, Pa.
    • Rickinson, A. B., and E. Kieff. 1996. Epstein-Barr Virus, p. 2397-2446. In B. N. Fields et al. (ed.), Fields virology, Lippincott-Raven, Philadelphia, Pa.
    • (1996) Fields Virology , pp. 2397-2446
    • Rickinson, A.B.1    Kieff, E.2
  • 54
    • 0023800131 scopus 로고
    • The 5′ flanking region of the gene for the Epstein-Barr virus-encoded nuclear antigen 2 contains a cell type specific cis-acting regulatory element that activates transcription in transfected B-cells
    • Ricksten, A., A. Olsson, T. Andersson, and L. Rymo. 1988. The 5′ flanking region of the gene for the Epstein-Barr virus-encoded nuclear antigen 2 contains a cell type specific cis-acting regulatory element that activates transcription in transfected B-cells. Nucleic Acids Res. 16:8391-8410.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 8391-8410
    • Ricksten, A.1    Olsson, A.2    Andersson, T.3    Rymo, L.4
  • 55
    • 0030860852 scopus 로고    scopus 로고
    • Mapping promoter regions that are hypersensitive to methylation-mediated inhibition of transcription: Application of the methylation cassette assay to the Epstein-Barr virus major latency promoter
    • Robertson, K. D., and R. F. Ambinder. 1997. Mapping promoter regions that are hypersensitive to methylation-mediated inhibition of transcription: application of the methylation cassette assay to the Epstein-Barr virus major latency promoter. J. Virol. 71:6445-6454.
    • (1997) J. Virol. , vol.71 , pp. 6445-6454
    • Robertson, K.D.1    Ambinder, R.F.2
  • 56
    • 0030689030 scopus 로고    scopus 로고
    • Methylation of the Epstein-Barr virus genome in normal lymphocytes
    • Robertson, K. D., and R. F. Ambinder. 1997. Methylation of the Epstein-Barr virus genome in normal lymphocytes. Blood 90:4480-4484.
    • (1997) Blood , vol.90 , pp. 4480-4484
    • Robertson, K.D.1    Ambinder, R.F.2
  • 57
    • 0028840682 scopus 로고
    • Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: Evidence that demethylation at a single CpG site is crucial
    • Robertson, K. D., S. D. Hayward, P. D. Ling, D. Samid, and R. F. Ambinder. 1995. Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial. Mol. Cell. Biol. 15:6150-6159.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6150-6159
    • Robertson, K.D.1    Hayward, S.D.2    Ling, P.D.3    Samid, D.4    Ambinder, R.F.5
  • 58
    • 0029909374 scopus 로고    scopus 로고
    • CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease
    • Robertson, K. D., A. Manns, L. J. Swinnen, J. C. Zong, M. L. Gulley, and R. F. Ambinder. 1996. CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease. Blood 88: 3129-3136.
    • (1996) Blood , vol.88 , pp. 3129-3136
    • Robertson, K.D.1    Manns, A.2    Swinnen, L.J.3    Zong, J.C.4    Gulley, M.L.5    Ambinder, R.F.6
  • 60
    • 0030885667 scopus 로고    scopus 로고
    • DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa
    • Rountree, M. R., and E. U. Selker. 1997. DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa. Genes Dev. 11:2383-2395.
    • (1997) Genes Dev. , vol.11 , pp. 2383-2395
    • Rountree, M.R.1    Selker, E.U.2
  • 61
    • 0026642994 scopus 로고
    • The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulated
    • Sample, J., E. B. Henson, and C. Sample. 1992. The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulated. J. Virol. 66:4654-4661.
    • (1992) J. Virol. , vol.66 , pp. 4654-4661
    • Sample, J.1    Henson, E.B.2    Sample, C.3
  • 62
    • 0031046602 scopus 로고    scopus 로고
    • Con-stitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency
    • Schaefer, B. C., E. Paulson, J. L. Strominger, and S. H. Speck. 1997. Con-stitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency. Mol. Cell. Biol. 17:873-886.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 873-886
    • Schaefer, B.C.1    Paulson, E.2    Strominger, J.L.3    Speck, S.H.4
  • 63
    • 0028838781 scopus 로고
    • Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group 1 Burkitt lymphoma cell lines
    • Schaefer, B. C., J. L. Strominger, and S. H. Speck. 1995. Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group 1 Burkitt lymphoma cell lines. Proc. Natl. Acad. Sci. USA 92:10565-10569.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10565-10569
    • Schaefer, B.C.1    Strominger, J.L.2    Speck, S.H.3
  • 64
    • 0029037531 scopus 로고
    • The Epstein-Barr virus BamHI F promoter is an early lytic promoter: Lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines
    • Schaefer, B. C., J. L. Strominger, and S. H. Speck. 1995. The Epstein-Barr virus BamHI F promoter is an early lytic promoter: lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines. J. Virol. 69:5039-5047.
    • (1995) J. Virol. , vol.69 , pp. 5039-5047
    • Schaefer, B.C.1    Strominger, J.L.2    Speck, S.H.3
  • 65
    • 0031022961 scopus 로고    scopus 로고
    • Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programs
    • Schaefer, B. C., J. L. Strominger, and S. H. Speck. 1997. Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programs. Mol. Cell. Biol. 17:364-377.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 364-377
    • Schaefer, B.C.1    Strominger, J.L.2    Speck, S.H.3
  • 66
    • 0027250816 scopus 로고
    • Simian foamy virus type 3 (SFV-3) in latently infected Vero cells: Reactivation by demethylation of proviral DNA
    • Schweizer, M., U. Fleps, A. Jackle, R. Renne, R. Turek, and D. Neumann-Haefelin. 1993. Simian foamy virus type 3 (SFV-3) in latently infected Vero cells: reactivation by demethylation of proviral DNA. Virology 192:663-666.
    • (1993) Virology , vol.192 , pp. 663-666
    • Schweizer, M.1    Fleps, U.2    Jackle, A.3    Renne, R.4    Turek, R.5    Neumann-Haefelin, D.6
  • 67
    • 0000186220 scopus 로고
    • Transcription of Epstein-Barr virus in latently infected, growth-transformed lymphocytes
    • G. Klein (ed.). Raven Press, New York, N.Y.
    • Speck, S. H., and J. D. Strominger. 1989. Transcription of Epstein-Barr virus in latently infected, growth-transformed lymphocytes, p. 133-150. In G. Klein (ed.), Advances in viral oncology. Raven Press, New York, N.Y.
    • (1989) Advances in Viral Oncology , pp. 133-150
    • Speck, S.H.1    Strominger, J.D.2
  • 68
    • 0025739303 scopus 로고
    • EBNA-2 trans-activates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus
    • Sung, N. S., S. Kenney, D. Gutsch, and J. S. Pagano. 1991. EBNA-2 trans-activates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus. J. Virol. 65:2164-2169.
    • (1991) J. Virol. , vol.65 , pp. 2164-2169
    • Sung, N.S.1    Kenney, S.2    Gutsch, D.3    Pagano, J.S.4
  • 69
    • 0027945043 scopus 로고
    • Reciprocal regulation of the Epstein-Barr virus BamHI-F promoter by EBNA-1 and an E2F transcription factor
    • Sung, N. S., J. Wilson, M. Davenport, N. D. Sista, and J. S. Pagano. 1994. Reciprocal regulation of the Epstein-Barr virus BamHI-F promoter by EBNA-1 and an E2F transcription factor. Mol. Cell. Biol. 14:7144-7152.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7144-7152
    • Sung, N.S.1    Wilson, J.2    Davenport, M.3    Sista, N.D.4    Pagano, J.S.5
  • 70
    • 0032520028 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) in endemic Burkitt's lymphoma: Molecular analysis of primary tumor tissue
    • Erratum, 91:3091
    • Tao, Q., K. D. Robertson, A. Manns, A. Hildesheim, and R. F. Ambinder. 1998. Epstein-Barr virus (EBV) in endemic Burkitt's lymphoma: molecular analysis of primary tumor tissue. Blood 91:1373-1381. (Erratum, 91:3091.)
    • (1998) Blood , vol.91 , pp. 1373-1381
    • Tao, Q.1    Robertson, K.D.2    Manns, A.3    Hildesheim, A.4    Ambinder, R.F.5
  • 71
    • 0031870242 scopus 로고    scopus 로고
    • The Epstein-Barr virus major latent promoter Qp is constitutively active, hypomethylated, and methylation sensitive
    • Tao, Q., K. D. Robertson, A. Manns, A. Hildesheim, and R. F. Ambinder. 1998. The Epstein-Barr virus major latent promoter Qp is constitutively active, hypomethylated, and methylation sensitive. J. Virol. 72:7075-7083.
    • (1998) J. Virol. , vol.72 , pp. 7075-7083
    • Tao, Q.1    Robertson, K.D.2    Manns, A.3    Hildesheim, A.4    Ambinder, R.F.5
  • 72
    • 0028130271 scopus 로고
    • Epstein-Barr virus latency in blood mononuclear cells: Analysis of viral gene transcription during primary infection and in the carrier state
    • Tierney, R. J., N. Steven, L. S. Young, and A. B. Rickinson. 1994. Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier state. J. Virol. 68:7374-7385.
    • (1994) J. Virol. , vol.68 , pp. 7374-7385
    • Tierney, R.J.1    Steven, N.2    Young, L.S.3    Rickinson, A.B.4
  • 73
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Letter
    • Walsh, C. P., J. R. Chaillet, and T. H. Bestor. 1998. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat. Genet. 20:116-117. (Letter.)
    • (1998) Nat. Genet. , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 75
    • 0024407780 scopus 로고
    • Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes
    • Woisetschlaeger, M., J. L. Strominger, and S. H. Speck. 1989. Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes. Proc. Natl. Acad. Sci. USA 86:6498-6502.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6498-6502
    • Woisetschlaeger, M.1    Strominger, J.L.2    Speck, S.H.3
  • 77
    • 0030782146 scopus 로고    scopus 로고
    • B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1
    • Yoo, L. I., M. Mooney, M. T. Puglielli, and S. H. Speck. 1997. B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1. J. Virol. 71:9134-9142.
    • (1997) J. Virol. , vol.71 , pp. 9134-9142
    • Yoo, L.I.1    Mooney, M.2    Puglielli, M.T.3    Speck, S.H.4


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