Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein

PLoS Pathogens

Volumn 4, Issue 3, 2008, Pages

  Karlsson, Questa H ^a   Schelcher, Celine ^a   Verrall, Elizabeth ^a   Petosa, Carlo ^b   Sinclair, Alison J ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; CYTOSINE; GENOMIC RNA; IMMEDIATE EARLY PROTEIN BZLF1; SERINE; BZLF1 PROTEIN, HERPESVIRUS 4, HUMAN; DNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

ARTICLE; BIOCHEMISTRY; BURKITT LYMPHOMA; CELL ACTIVATION; CELL LINE; CONTROLLED STUDY; DNA DETERMINATION; DNA METHYLATION; ENZYME REGULATION; EPIGENETICS; EPSTEIN BARR VIRUS; GENE ACTIVATION; GENE INTERACTION; GENE SILENCING; GENETIC SELECTION; HUMAN; HUMAN CELL; IN VITRO SELECTION; IN VIVO STUDY; LIFE CYCLE; MOLECULAR MODEL; MONONUCLEOSIS; MUTANT; PREDICTION; PROTEIN BINDING; VIRUS LATENCY; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOGENICITY; TUMOR CELL LINE; VIRUS GENOME;

HUMAN HERPESVIRUS 4;

BASE SEQUENCE; CELL LINE, TUMOR; CYSTEINE; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, VIRAL; GENE SILENCING; GENOME, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; RESPONSE ELEMENTS; SERINE; TRANS-ACTIVATORS; VIRAL PROTEINS;

EID: 42949174160     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000005     Document Type: Article

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