Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas

International Journal of Cancer

Volumn 126, Issue 10, 2010, Pages 2282-2295

  Beckner, Marie E ^a,d   Fellows Mayle, Wendy ^a   Zhang, Zhe ^b,e   Agostino, Naomi R ^a   Kant, Jeffrey A ^a,b   Day, Billy W ^b   Pollack, Ian F ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d LOUISIANA STATE UNIVERSITY   (United States)

^e University of Missouri   (United States)

Author keywords

Atp citrate lyase; Cell migration; Glioblastoma; Glycolysis; Invasion

Indexed keywords

ADENOSINE TRIPHOSPHATE CITRATE LYASE; CITRIC ACID; ENOLASE; HYDROXYCITRIC ACID; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; RADICICOL; DNA BINDING PROTEIN; ENO1 PROTEIN, HUMAN; ENZYME INHIBITOR; MACROLIDE; PROTEIN TYROSINE KINASE; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BRAIN TUMOR; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; DATA BASE; DRUG ACTIVITY; ENO1 GENE; GENE; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; METABOLIC ACIDOSIS; PRIORITY JOURNAL; PSEUDOPODIUM; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; CELL MOTION; CHI SQUARE DISTRIBUTION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; POLYMERASE CHAIN REACTION; RAT; TUMOR CELL LINE;

ANIMALS; ATP CITRATE (PRO-S)-LYASE; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHI-SQUARE DISTRIBUTION; CITRATES; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; GLIOMA; GLYCOLYSIS; HUMANS; MACROLIDES; PHOSPHOPYRUVATE HYDRATASE; POLYMERASE CHAIN REACTION; PROTEIN-TYROSINE KINASES; PSEUDOPODIA; RATS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 77951239243     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24918     Document Type: Article

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