Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence

Journal of Biological Chemistry

Volumn 285, Issue 15, 2010, Pages 11326-11335

  Whibley, Catherine ^a   Odell, Adam F ^a   Nedelko, Tatiana ^c   Balaburski, Gregor ^b   Murphy, Maureen ^b   Liu, Zhipei ^d   Stevens, Louisa ^a   Walker, John H ^a   Routledge, Michael ^a   Hollstein, Monica ^a,c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b FOX CHASE CANCER CENTER   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; CULTURE CONDITIONS; DNA DAMAGES; GENETIC ALTERATIONS; GENETIC CONTROL; HUMAN TUMORS; IMMORTALIZED CELLS; MURINE EMBRYONIC FIBROBLASTS; OXYGEN LEVELS; P53 GENE; POINT MUTATIONS; TRANSACTIVATION; WILD TYPES;

FIBROBLASTS; GENETIC ENGINEERING; OXYGEN;

CELL CULTURE;

ARF PROTEIN; CYTOSINE; DNA; GLUTAMINE; OXYGEN; PROTEIN P19; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TYROSINE;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL AGING; CELL ASSAY; CELL CULTURE; CELL FUNCTION; CELL IMMORTALIZATION; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE DELETION; GENE MUTATION; GENETIC REGULATION; GENOTYPE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; STRAIN DIFFERENCE; TRANSACTIVATION; WILD TYPE; YEAST CELL;

ALLELES; ANIMALS; CELL AGING; COMET ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA DAMAGE; FIBROBLASTS; GENE DELETION; GENES, P53; MICE; MUTATION; OXYGEN; POLYMORPHISM, GENETIC; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE; MUS;

EID: 77951233870     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.064444     Document Type: Article

References (56)

1. Banito, A., Rashid, S. T., Acosta, J. C., Li, S., Pereira, C. F., Geti, I., Pinho, S., Silva, J. C., Azuara, V., Walsh, M., Vallier, L., and Gil, J. (2009) Genes Dev. 23, 2134-2139
2. Kawamura, T., Suzuki, J., Wang, Y. V., Menendez, S., Morera, L. B., Raya, A., Wahl, G. M., and Belmonte, J. C. (2009) Nature 460, 1140-1144
3. Li, H., Collado, M., Villasante, A., Strati, K., Ortega, S., Cañamero, M., Blasco, M. A., and Serrano, M. (2009) Nature 460, 1136-1139
4. Collado, M., Blasco, M. A., and Serrano, M. (2007) Cell 130, 223-233
5. Martins, C. P., Brown-Swigart, L., and Evan, G. I. (2006) Cell 127, 1323-1334
6. Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C., and Lowe, S. W. (2007) Nature 445, 656-660
7. Utikal, J., Polo, J. M., Stadtfeld, M., Maherali, N., Kulalert, W., Walsh, R. M., Khalil, A., Rheinwald, J. G., and Hochedlinger, K. (2009) Nature 460, 1145-1148
8. Harvey, D. M., and Levine, A. J. (1991) Genes Dev. 5, 2375-2385
9. Roussel, M. F. (2002) Cancer Cell 2, 434-435
10. Kamijo, T., Weber, J. D., Zambetti, G., Zindy, F., Roussel, M. F., and Sherr, C. J. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 8292-8297
11. Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., and Lowe, S. W. (1997) Cell 88, 593-602
12. Dirac, A. M., and Bernards, R. (2003) J. Biol. Chem. 278, 11731-11734
13. Leal, J. F., Fominaya, J., Cascón, A., Guijarro, M. V., Blanco-Aparicio, C., Lleonart, M., Castro, M. E., Ramon, Y., Cajal, S., Robledo, M., Beach, D. H., and Carnero, A. (2008) Oncogene 27, 1961-1970
14. Shvarts, A., Brummelkamp, T. R., Scheeren, F., Koh, E., Daley, G. Q., Spits, H., and Bernards, R. (2002) Genes Dev. 16, 681-686
15. Nogueira, V., Park, Y., Chen, C. C., Xu, P. Z., Chen, M. L., Tonic, I., Unterman, T., and Hay, N. (2008) Cancer Cell 14, 458-470
16. Hahn, W. C., and Weinberg, R. A. (2002) Nat. Rev. Cancer 2, 331-341
17. Luo, J. L., Yang, Q., Tong, W. M., Hergenhahn, M., Wang, Z. Q., and Hollstein, M. (2001) Oncogene 20, 320-328
18. Song, H., Hollstein, M., and Xu, Y. (2007) Nat. Cell Biol. 9, 573-580
19. Hergenhahn, M., Luo, J. L., and Hollstein, M. (2004) Cell Cycle 3, 738-741
20. Jaworski, M., Hailfinger, S., Buchmann, A., Hergenhahn, M., Hollstein, M., Ittrich, C., and Schwarz, M. (2005) Carcinogenesis 26, 1829-1834
21. Whibley, C., Pharoah, P. D., and Hollstein, M. (2009) Nat. Rev. Cancer 9, 95-107
22. Reinbold, M., Luo, J. L., Nedelko, T., Jerchow, B., Murphy, M. E., Whibley, C., Wei, Q., and Hollstein, M. (2008) Oncogene 27, 2788-2794
23. Hirabayashi, Y., Taniuchi, S., and Kobayashi, Y. (1985) J. Immunol. Methods 82, 253-259
24. Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I., and Pereira-Smith, O. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 9363-9367
25. Collins, A. R. (2004) Mol. Biotechnol. 26, 249-261
26. Ostling, O., and Johanson, K. J. (1984) Biochem. Biophys. Res. Commun. 123, 291-298
27. Tam, A. S., Devereux, T. R., Patel, A. C., Foley, J. F., Maronpot, R. R., and Massey, T. E. (2003) Carcinogenesis 24, 121-132
28. Parrinello, S., Samper, E., Krtolica, A., Goldstein, J., Melov, S., and Campisi, J. (2003) Nat. Cell Biol. 5, 741-747
29. Busuttil, R. A., Rubio, M., Dollé, M. E., Campisi, J., and Vijg, J. (2003) Aging Cell 2, 287-294
30. Collins, A. R., Duthie, S. J., and Dobson, V. L. (1993) Carcinogenesis 14, 1733-1735
31. Hainaut, P., and Hollstein, M. (2000) Adv. Cancer Res. 77, 81-137
32. Petitjean, A., Mathe, E., Kato, S., Ishioka, C., Tavtigian, S. V., Hainaut, P., and Olivier, M. (2007) Hum. Mutat. 28, 622-629
33. Brosh, R., and Rotter, V. (2010) Nat. Rev. Cancer 6, 17-29
34. Matheu, A., Maraver, A., and Serrano, M. (2008) Cancer Res. 68, 6031-6034
35. Bond, J. A., Blaydes, J. P., Rowson, J., Haughton, M. F., Smith, J. R., Wynford- Thomas, D., and Wyllie, F. S. (1995) Cancer Res. 55, 2404-2409
36. Wynford-Thomas, D. (1996) J. Pathol. 180, 118-121
37. Liu, Z., Hergenhahn, M., Schmeiser, H. H., Wogan, G. N., Hong, A., and Hollstein, M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 2963-2968
38. vom Brocke, J., Krais, A., Whibley, C., Hollstein, M. C., and Schmeiser, H. H. (2009) Mutagenesis 24, 17-23
39. Liu, Z., Muehlbauer, K. R., Schmeiser, H. H., Hergenhahn, M., Belharazem, D., and Hollstein, M. C. (2005) Cancer Res. 65, 2583-2587
40. Nedelko, T., Arlt, V. M., Phillips, D. H., and Hollstein, M. (2009) Int. J. Cancer 124, 987-990
41. Pfeifer, G. P., and Besaratinia, A. (2009) Hum. Genet. 125, 493-506
42. Kato, S., Han, S. Y., Liu, W., Otsuka, K., Shibata, H., Kanamaru, R., and Ishioka, C. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 8424-8429
43. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
44. Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., and Roussel, M. F. (1998) Genes Dev. 12, 2424-2433
45. Randle, D. H., Zindy, F., Sherr, C. J., and Roussel, M. F. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 9654-9659
46. Esteller, M. (2002) Oncogene 21, 5427-5440
47. Esteller, M., Tortola, S., Toyota, M., Capella, G., Peinado, M. A., Baylin, S. B., and Herman, J. G. (2000) Cancer Res. 60, 129-133
48. Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P., Davidson, N. E., Sidransky, D., and Baylin, S. B. (1995) Cancer Res. 55, 4525-4530
49. Moll, U. M., Riou, G., and Levine, A. J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 7262-7266
50. Jones, S., Zhang, X., Parsons, D. W., Lin, J. C., Leary, R. J., Angenendt, P., Mankoo, P., Carter, H., Kamiyama, H., Jimeno, A., Hong, S. M., Fu, B., Lin, M. T., Calhoun, E. S., Kamiyama, M., Walter, K., Nikolskaya, T., Nikolsky, Y., Hartigan, J., Smith, D. R., Hidalgo, M., Leach, S. D., Klein, A. P., Jaffee, E. M., Goggins, M., Maitra, A., Iacobuzio-Donahue, C., Eshleman, J. R., Kern, S. E., Hruban, R. H., Karchin, R., Papadopoulos, N., Parmigiani, G., Vogelstein, B., Velculescu, V. E., and Kinzler, K. W. (2008) Science 321, 1801-1806
51. Sjöblom, T., Jones, S., Wood, L. D., Parsons, D. W., Lin, J., Barber, T. D., Mandelker, D., Leary, R. J., Ptak, J., Silliman, N., Szabo, S., Buckhaults, P., Farrell, C., Meeh, P., Markowitz, S. D., Willis, J., Dawson, D., Willson, J. K., Gazdar, A. F., Hartigan, J., Wu, L., Liu, C., Parmigiani, G., Park, B. H., Bachman, K. E., Papadopoulos, N., Vogelstein, B., Kinzler, K. W., and Velculescu, V. E. (2006) Science 314, 268-274
52. Johnson, T. M., Meade, K., Pathak, N., Marques, M. R., and Attardi, L. D. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 1215-1220
53. Cook, W. D., and McCaw, B. J. (2000) Oncogene 19, 3434-3438
54. Maslov, A. Y., and Vijg, J. (2009) Biochim. Biophys. Acta 1790, 963-969
55. Vijg, J., and Dollé, M. E. (2002) Mech. Ageing Dev. 123, 907-915
56. Rittling, S. R., and Denhardt, D. T. (1992) Oncogene 7, 935-942