Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate α11 integrin chain expression in mesenchymal cells

Matrix Biology

Volumn 25, Issue 2, 2006, Pages 118-129

  Lu, Ning ^a,b   Heuchel, Rainer ^b   Barczyk, Malgorzata ^a,b   Zhang, Wan Ming ^a   Gullberg, Donald ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Ets 1; Integrin 11; Proximal promoter analysis; Sp1 Sp3

Indexed keywords

LUCIFERASE; MITHRAMYCIN; RNA; TRANSCRIPTION FACTOR ER81; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ARTICLE; BINDING SITE; CHROMATIN; CONTROLLED STUDY; DROSOPHILA; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MESENCHYME CELL; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CELL LINE, TUMOR; HUMANS; INTEGRIN ALPHA CHAINS; MESODERM; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEIN C-ETS-1; SP3 TRANSCRIPTION FACTOR;

EID: 32544432513     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2005.10.002     Document Type: Article

References (61)

1. D.L. Baker, V. Dave, T. Reed, and M. Periasamy Multiple Sp1 binding sites in the cardiac/slow twitch muscle sarcoplasmic reticulum Ca2+-ATPase gene promoter are required for expression in Sol8 muscle cells J. Biol. Chem. 271 1996 5921 5928
2. T. Bengtsson, A. Aszodi, C. Nicolae, E.B. Hunziker, E. Lundgren-Akerlund, and R. Fassler Loss of α10β1 integrin expression leads to moderate dysfunction of growth plate chondrocytes J. Cell Sci. 118 2005 929 936
3. K.L. Block, Y. Shou, and M. Poncz An Ets/Sp1 interaction in the 5′-flanking region of the megakaryocyte-specific α IIb gene appears to stabilize Sp1 binding and is essential for expression of this TATA-less gene Blood 88 1996 2071 2080
4. S.W. Blume, R.C. Snyder, R. Ray, S. Thomas, C.A. Koller, and D.M. Miller Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo J. Clin. Invest. 88 1991 1613 1621
5. P. Bouwman, and S. Philipsen Regulation of the activity of Sp1-related transcription factors Mol. Cell. Endocrinol. 195 2002 27 38
6. P. Bouwman, H. Gollner, H.P. Elsasser, G. Eckhoff, A. Karis, F. Grosveld, S. Philipsen, and G. Suske Transcription factor Sp3 is essential for post-natal survival and late tooth development EMBO J. 19 2000 655 661
7. L. Camper, U. Hellman, and E. Lundgren-Akerlund Isolation, cloning, and sequence analysis of the integrin subunit α10, a β1-associated collagen binding integrin expressed on chondrocytes J. Biol. Chem. 273 1998 20383 20389
8. L. Camper, K. Holmvall, C. Wangnerud, A. Aszodi, and E. Lundgren-Akerlund Distribution of the collagen-binding integrin α10β1 during mouse development Cell Tissue Res. 306 2001 107 116
9. S. Chakraborti, M. Mandal, S. Das, A. Mandal, and T. Chakraborti Regulation of matrix metalloproteinases: an overview Mol. Cell. Biochem. 253 2003 269 285
10. J. Chen, T.G. Diacovo, D.G. Grenache, S.A. Santoro, and M.M. Zutter The α2 integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis Am. J. Pathol. 161 2002 337 344
11. J. Czuwara-Ladykowska, F. Shirasaki, P. Jackers, D.K. Watson, and M. Trojanowska Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway J. Biol. Chem. 276 2001 20839 20848
12. S.K. Dickeson, and S.A. Santoro Ligand recognition by the I domain-containing integrins Cell. Mol. Life Sci. 54 1998 556 566
13. J. Dittmer, C.A. Pise-Masison, K.E. Clemens, K.S. Choi, and J.N. Brady Interaction of human T-cell lymphotropic virus type I Tax, Ets1, and Sp1 in transactivation of the PTHrP P2 promoter J. Biol. Chem. 272 1997 4953 4958
14. J.L. Duband, A.M. Belkin, J. Syfrig, J.P. Thiery, and V.E. Koteliansky Expression of α1 integrin, a laminin-collagen receptor, during myogenesis and neurogenesis in the avian embryo Development 116 1992 585 600
15. H. Gardner, J. Kreidberg, V. Koteliansky, and R. Jaenisch Deletion of integrin α1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion Dev. Biol. 175 1996 301 313
16. H. Gardner, A. Broberg, A. Pozzi, M. Laato, and J. Heino Absence of integrin α1β1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis J. Cell Sci. 112 1999 263 272
17. F. Gilles, M.B. Raes, D. Stehelin, B. Vandenbunder, and V. Fafeur The c-ets-1 proto-oncogene is a new early-response gene differentially regulated by cytokines and growth factors in human fibroblasts Exp. Cell Res. 222 1996 370 378
18. M.E. Gingras, K. Larouche, N. Larouche, S. Leclerc, C. Salesse, and S.L. Guerin Regulation of the integrin subunit α5 gene promoter by the transcription factors Sp1/Sp3 is influenced by the cell density in rabbit corneal epithelial cells Invest. Ophthalmol. Vis. Sci. 44 2003 3742 3755
19. H. Gollner, C. Dani, B. Phillips, S. Philipsen, and G. Suske Impaired ossification in mice lacking the transcription factor Sp3 Mech. Dev. 106 2001 77 83
20. S. Gruner, M. Prostredna, V. Schulte, T. Krieg, B. Eckes, C. Brakebusch, and B. Nieswandt Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo Blood 102 2003 4021 4027
21. D. Gullberg, and E. Lundgren-Åkerlund Collagen-binding I domain integrins - what do they do? Prog. Histochem. Cytochem. 37 2002 3 54
22. B. Han, N. Liu, X. Yang, H.B. Sun, and Y.C. Yang MRG1 expression in fibroblasts is regulated by Sp1/Sp3 and an Ets transcription factor J. Biol. Chem. 276 2001 7937 7942
23. A.J. Hayes, M. Benjamin, and J.R. Ralphs Role of actin stress fibres in the development of the intervertebral disc: cytoskeletal control of extracellular matrix assembly Dev. Dyn. 215 1999 179 189
24. L. He, L.K. Pappan, D.G. Grenache, Z. Li, D.M. Tollefsen, S.A. Santoro, and M.M. Zutter The contributions of the α 2β1 integrin to vascular thrombosis in vivo Blood 102 2003 3652 3657
25. O. Holtkotter, B. Nieswandt, N. Smyth, W. Muller, M. Hafner, V. Schulte, T. Krieg, and B. Eckes Integrin α2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen J. Biol. Chem. 277 2002 10789 10794
26. R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
27. B. Jacquelin, D. Rozenshteyn, S. Kanaji, J.A. Koziol, A.T. Nurden, and T.J. Kunicki Characterization of inherited differences in transcription of the human integrin α2 Gene J. Biol. Chem. 276 2001 23518 23524
28. A. Kern, and E.E. Marcantonio Role of the I-domain in collagen binding specificity and activation of the integrins α1β1 and α2β1 J. Cell. Physiol. 176 1998 634 641
29. C.G. Knight, L.F. Morton, A.R. Peachey, D.S. Tuckwell, R.W. Farndale, and M.J. Barnes The collagen-binding A-domains of integrins α1β1 and α2β1 recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens J. Biol. Chem. 275 2000 35 40
30. T.J. Kunicki The influence of platelet collagen receptor polymorphisms in hemostasis and thrombotic disease Arterioscler. Thromb. Vasc. Biol. 22 2002 14 20
31. T.J. Kunicki, and D.J. Nugent The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis Vox Sang 83 Suppl 1 2002 85 90
32. W. Lee, J. Sodek, and C.A. McCulloch Role of integrins in regulation of collagen phagocytosis by human fibroblasts J. Cell. Physiol. 168 1996 695 704
33. T.T. Li, S. Larrucea, S. Souza, S.M. Leal, J.A. Lopez, E.M. Rubin, B. Nieswandt, and P.F. Bray Genetic variation responsible for mouse strain differences in integrin α2 expression is associated with altered platelet responses to collagen Blood 103 2004 3396 3402
34. M. Marin, A. Karis, P. Visser, F. Grosveld, and S. Philipsen Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation Cell 89 1997 619 628
35. W. Nishida, M. Nakamura, S. Mori, M. Takahashi, Y. Ohkawa, S. Tadokoro, K. Yoshida, K. Hiwada, K. Hayashi, and K. Sobue A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes J. Biol. Chem. 277 2002 7308 7317
36. M. Pfaff, W. Gohring, J.C. Brown, and R. Timpl Binding of purified collagen receptors α1β1, α2β1 and RGD-dependent integrins to laminins and laminin fragments Eur. J. Biochem. 225 1994 975 984
37. S.N. Popova, B. Rodriguez-Sanchez, A. Liden, C. Betsholtz, T. Van Den Bos, and D. Gullberg The mesenchymal α11β1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens Dev. Biol. 270 2004 427 442
38. A. Pozzi, K.K. Wary, F.G. Giancotti, and H.A. Gardner Integrin α1α1 mediates a unique collagen-dependent proliferation pathway in vivo J. Cell Biol. 142 1998 587 594
39. A. Pozzi, P.E. Moberg, L.A. Miles, S. Wagner, P. Soloway, and H.A. Gardner Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization Proc. Natl. Acad. Sci. U. S. A. 97 2000 2202 2207
40. G. Segal, W. Lee, P.D. Arora, M. McKee, G. Downey, and C.A. McCulloch Involvement of actin filaments and integrins in the binding step in collagen phagocytosis by human fibroblasts J. Cell Sci. 114 2001 119 129
41. D.R. Senger, K.P. Claffey, J.E. Benes, C.A. Perruzzi, A.P. Sergiou, and M. Detmar Angiogenesis promoted by vascular endothelial growth factor: regulation through α1β1 and α2β1 integrins Proc. Natl. Acad. Sci. U. S. A. 94 1997 13612 13617
42. A.D. Sharrocks The ETS-domain transcription factor family Nat. Rev., Mol. Cell Biol. 2 2001 827 837
43. F. Shirasaki, H.A. Makhluf, C. LeRoy, D.K. Watson, and M. Trojanowska Ets transcription factors cooperate with Sp1 to activate the human tenascin-C promoter Oncogene 18 1999 7755 7764
44. G. Suske The Sp-family of transcription factors Gene 238 1999 291 300
45. A. Tajima, Y. Miyamoto, H. Kadowaki, and M. Hayashi Mouse integrin av promoter is regulated by transcriptional factors Ets and Sp1 in melanoma cells Biochim. Biophys. Acta 1492 2000 377 384
46. Y. Takagi, M. Nomizu, D. Gullberg, A.J. MacKrell, D.R. Keene, Y. Yamada, and J.H. Fessler Conserved neuron promoting activity in Drosophila and vertebrate laminin α1 J. Biol. Chem 271 1996 18074 18081
47. C.-F. Tiger, F. Fougerousse, G. Grundström, T. Velling, and D. Gullberg α11β1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal non-muscle cells Dev. Biol. 237 2001 116 129
48. D. Tuckwell, D.A. Calderwood, L.J. Green, and M.J. Humphries Integrin α2 I-domain is a binding site for collagens J. Cell Sci. 108 1995 1629 1637
49. M. Tulla, O.T. Pentikainen, T. Viitasalo, J. Kapyla, U. Impola, P. Nykvist, L. Nissinen, M.S. Johnson, and J. Heino Selective binding of collagen subtypes by integrin α 1I, β 2I, and α 10I domains J. Biol. Chem. 276 2001 48206 48212
50. T. Velling, M. Kusche-Gullberg, T. Sejersen, and D. Gullberg cDNA cloning and chromosomal localization of human α11 integrin. A collagen-binding, I domain-containing, β1-associated integrin α-chain present in muscle tissues J. Biol. Chem. 274 1999 25735 25742
51. T. Velling, J. Risteli, K. Wennerberg, D.F. Mosher, and S. Johansson Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins α11β1 and α2β1 J. Biol. Chem. 277 2002 37377 37381
52. F. Verrecchia, J. Rossert, and A. Mauviel Blocking sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: implications for the treatment of tissue fibrosis J. Invest. Dermatol. 116 2001 755 763
53. V. Vlaeminck-Guillem, S. Carrere, F. Dewitte, D. Stehelin, X. Desbiens, and M. Duterque-Coquillaud The Ets family member Erg gene is expressed in mesodermal tissues and neural crests at fundamental steps during mouse embryogenesis Mech. Dev. 91 2000 331 335
54. B. Wasylyk, J. Hagman, and A. Gutierrez-Hartmann Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway Trends Biochem. Sci. 23 1998 213 216
55. D.J. White, S. Puranen, M.S. Johnson, and J. Heino The collagen receptor subfamily of the integrins Int. J. Biochem. Cell Biol. 36 2004 1405 1410
56. J.E. Wu, and S.A. Santoro Complex patterns of expression suggest extensive roles for the α2β1 integrin in murine development Dev. Dyn. 199 1994 292 314
57. W.-M. Zhang, C. Bergman, T. Velling, M. Kusche-Gullberg, and D. Gullberg Analysis of the human integrin α11 gene (ITGA11) and its promoter Matrix. Biol. 21 2002 513 523
58. W.-M. Zhang, J. Käpylä, J. Santeri Puranen, R.W. Farndale, C.-F. Tiger, O.T. Pentikäinen, M.S. Johnson, J. Heino, and D. Gullberg α11β1 integrin recognizes the GFOGER sequence in interstitial collagens J. Biol. Chem. 278 2003 7270 7277
59. M.M. Zutter, S.A. Santoro, A.S. Painter, Y.L. Tsung, and A. Gafford The human α2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression J. Biol. Chem. 269 1994 463 469
60. M.M. Zutter, E.E. Ryan, and A.D. Painter Binding of phosphorylated Sp1 protein to tandem Sp1 binding sites regulates α2 integrin gene core promoter activity Blood 90 1997 678 689
61. M.M. Zutter, A.D. Painter, and X. Yang The Megakaryocyte/Platelet- specific enhancer of the α2β1 integrin gene: two tandem AP1 sites and the mitogen-activated protein kinase signaling cascade Blood 93 1999 1600 1611